Myeloid-derived suppressor cells in breast cancer

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

A novel role of hematopoietic CCL5 in promoting triple-negative mammary tumor progression by regulating generation of myeloid-derived suppressor cells

(2012) Yan Zhang et al.   CELL RESEARCH

MicroRNA-494 Is Required for the Accumulation and Functions of Tumor-Expanded Myeloid-Derived Suppressor Cells via Targeting of PTEN

(2012) Y. Liu et al.   JOURNAL OF IMMUNOLOGY

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

(2012) Mélanie Bruchard et al.   NATURE MEDICINE

IDO Is a Nodal Pathogenic Driver of Lung Cancer and Metastasis Development

(2012) Courtney Smith et al.   Cancer Discovery

A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells

(2011) S. Solito et al.   BLOOD

Phase 2 study of neoadjuvant treatment with NOV-002 in combination with doxorubicin and cyclophosphamide followed by docetaxel in patients with HER-2 negative clinical stage II–IIIc breast cancer

(2011) A. J. Montero et al.   BREAST CANCER RESEARCH AND TREATMENT

A Th1 cytokine–enriched microenvironment enhances tumor killing by activated T cells armed with bispecific antibodies and inhibits the development of myeloid-derived suppressor cells

(2011) Archana Thakur et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Myeloid-Derived Suppressor Cell Inhibition of the IFN Response in Tumor-Bearing Mice

(2011) B. L. Mundy-Bosse et al.   CANCER RESEARCH

Psychological stress is associated with altered levels of myeloid-derived suppressor cells in breast cancer patients

(2011) Bethany L. Mundy-Bosse et al.   CELLULAR IMMUNOLOGY

The role of interleukin-12 on modulating myeloid-derived suppressor cells, increasing overall survival and reducing metastasis

(2011) Catherine E. Steding et al.   IMMUNOLOGY

Critical choices for modeling breast cancer in transgenic mouse models

(2011) Isabella Caligiuri et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice

(2011) Tangying Lu et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors

(2011) Sid P. Kerkar et al.   JOURNAL OF CLINICAL INVESTIGATION

Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells

(2011) Barbara Molon et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Functional characterization of human Cd33+ And Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines

(2011) Melissa G Lechner et al.   Journal of Translational Medicine

Oncolytic Herpes Simplex Virus 1 Encoding 15-Prostaglandin Dehydrogenase Mitigates Immune Suppression and Reduces Ectopic Primary and Metastatic Breast Cancer in Mice

(2011) J. D. Walker et al.   JOURNAL OF VIROLOGY

Characterization of the MDSC Proteome Associated with Metastatic Murine Mammary Tumors Using Label-Free Mass Spectrometry and Shotgun Proteomics

(2011) Angela M. Boutté et al.   PLoS One

Characterization of Cytokine-Induced Myeloid-Derived Suppressor Cells from Normal Human Peripheral Blood Mononuclear Cells

(2010) M. G. Lechner et al.   JOURNAL OF IMMUNOLOGY

Mechanism of T Cell Tolerance Induced by Myeloid-Derived Suppressor Cells

(2010) S. Nagaraj et al.   JOURNAL OF IMMUNOLOGY

GM-CSF is one of the main breast tumor-derived soluble factors involved in the differentiation of CD11b-Gr1- bone marrow progenitor cells into myeloid-derived suppressor cells

(2009) Johanna K. Morales et al.   BREAST CANCER RESEARCH AND TREATMENT

Therapeutic targeting of myeloid-derived suppressor cells

(2009) Stefano Ugel et al.   CURRENT OPINION IN PHARMACOLOGY

Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor

(2009) Bastian Hoechst et al.   HEPATOLOGY

Mammary tumor heterogeneity in the expansion of myeloid-derived suppressor cells

(2009) Moses K. Donkor et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Radiation-Induced Mammary Carcinogenesis in Rodent Models: What's Different from Chemical Carcinogenesis?

(2009) Tatsuhiko IMAOKA et al.   JOURNAL OF RADIATION RESEARCH

Cytokine Levels Correlate with Immune Cell Infiltration after Anti-VEGF Therapy in Preclinical Mouse Models of Breast Cancer

(2009) Christina L. Roland et al.   PLoS One

Radiofrequency thermal ablation of breast tumors combined with intralesional administration of IL-7 and IL-15 augments anti-tumor immune responses and inhibits tumor development and metastasis

(2008) Mehran Habibi et al.   BREAST CANCER RESEARCH AND TREATMENT

Adoptive transfer of HER2/neu-specific T cells expanded with alternating gamma chain cytokines mediate tumor regression when combined with the depletion of myeloid-derived suppressor cells

(2008) Johanna K. Morales et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy

(2008) C. Marcela Diaz-Montero et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein

(2008) Pingyan Cheng et al.   JOURNAL OF EXPERIMENTAL MEDICINE