RB-pathway disruption in breast cancer

RB status governs differential sensitivity to cytotoxic and molecularly-targeted therapeutic agents

(2011) Kristy R. Stengel et al.   CELL CYCLE

Prolactin Inhibits BCL6 Expression in Breast Cancer through a Stat5a-Dependent Mechanism

(2010) T. H. Tran et al.   CANCER RESEARCH

Regulation of RB Transcription In Vivo by RB Family Members

(2010) D. L. Burkhart et al.   MOLECULAR AND CELLULAR BIOLOGY

Amplification of LAPTM4B and YWHAZ contributes to chemotherapy resistance and recurrence of breast cancer

(2010) Yang Li et al.   NATURE MEDICINE

Therapeutic CDK4/6 inhibition in breast cancer: key mechanisms of response and failure

(2010) J L Dean et al.   ONCOGENE

Most Basal-like Breast Carcinomas Demonstrate the Same Rb−/p16+ Immunophenotype as the HPV-related Poorly Differentiated Squamous Cell Carcinomas Which They Resemble Morphologically

(2009) Andrea Proctor Subhawong et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

High prevalence of retinoblastoma protein loss in triple-negative breast cancers and its association with a good prognosis in patients treated with adjuvant chemotherapy

(2009) D. Trere et al.   ANNALS OF ONCOLOGY

Loss of Phosphatase and Tensin Homologue Deleted on Chromosome 10 Engages ErbB3 and Insulin-Like Growth Factor-I Receptor Signaling to Promote Antiestrogen Resistance in Breast Cancer

(2009) T. W. Miller et al.   CANCER RESEARCH

Human and mouse switch-like genes share common transcriptional regulatory mechanisms for bimodality

(2008) Adam Ertel et al.   BMC GENOMICS

Development of Resistance to Targeted Therapies Transforms the Clinically Associated Molecular Profile Subtype of Breast Tumor Xenografts

(2008) C. J. Creighton et al.   CANCER RESEARCH

Loss of Retinoblastoma Tumor Suppressor Protein Makes Human Breast Cancer Cells More Sensitive to Antimetabolite Exposure

(2008) M. Derenzini et al.   CLINICAL CANCER RESEARCH

Triple-Negative Breast Cancer: Risk Factors to Potential Targets

(2008) B. P. Schneider et al.   CLINICAL CANCER RESEARCH