Pathogen interactions with endothelial cells and the induction of innate and adaptive immunity

Protective and Pathological Immunity during Central Nervous System Infections

(2017) Robyn S. Klein et al.   IMMUNITY

pIgR and PECAM-1 bind to pneumococcal adhesins RrgA and PspC mediating bacterial brain invasion

(2017) Federico Iovino et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Endothelial TLR4 and the microbiome drive cerebral cavernous malformations

(2017) Alan T. Tang et al.   NATURE

Vascular heterogeneity and specialization in development and disease

(2017) Michael Potente et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pathogens’ toolbox to manipulate human complement

(2017) Francisco J. Fernández et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Migratory dendritic cells acquire and present lymphatic endothelial cell-archived antigens during lymph node contraction

(2017) Ross M. Kedl et al.   Nature Communications

Adhesion of Toxoplasma gondii tachyzoite-infected vehicle leukocytes to capillary endothelial cells triggers timely parasite egression

(2017) Minami Baba et al.   Scientific Reports

The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis

(2016) Carmen Gerlach et al.   IMMUNITY

How neutrophils kill fungi

(2016) Roel P. Gazendam et al.   IMMUNOLOGICAL REVIEWS

MDA-5 activation by cytoplasmic double-stranded RNA impairs endothelial function and aggravates atherosclerosis

(2016) Tobias Asdonk et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Lymphatic endothelial cells are a replicative niche for Mycobacterium tuberculosis

(2016) Thomas R. Lerner et al.   JOURNAL OF CLINICAL INVESTIGATION

Intracellular RIG-I Signaling Regulates TLR4-Independent Endothelial Inflammatory Responses to Endotoxin

(2016) Jill Moser et al.   JOURNAL OF IMMUNOLOGY

cGAS-STING Signaling Regulates Initial Innate Control of Cytomegalovirus Infection

(2016) Chan-Wang J. Lio et al.   JOURNAL OF VIROLOGY

The endothelial protein C receptor rs867186-GG genotype is associated with increased soluble EPCR and could mediate protection against severe malaria

(2016) Estela Shabani et al.   Scientific Reports

CD8+ T Cells Induce Fatal Brainstem Pathology during Cerebral Malaria via Luminal Antigen-Specific Engagement of Brain Vasculature

(2016) Phillip A. Swanson et al.   PLoS Pathogens

Endothelial cells are a replicative niche for entry of Toxoplasma gondii to the central nervous system

(2016) Christoph Konradt et al.   Nature Microbiology

Antigen archiving by lymph node stroma: A novel function for the lymphatic endothelium

(2015) Ross M. Kedl et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Dengue Virus Infection of Primary Endothelial Cells Induces Innate Immune Responses, Changes in Endothelial Cells Function and Is Restricted by Interferon-Stimulated Responses

(2015) Julie K. Calvert et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Brain Swelling and Death in Children with Cerebral Malaria

(2015) Karl B. Seydel et al.   NEW ENGLAND JOURNAL OF MEDICINE

A gut-vascular barrier controls the systemic dissemination of bacteria

(2015) Ilaria Spadoni et al.   SCIENCE

Activated Brain Endothelial Cells Cross-Present Malaria Antigen

(2015) Shanshan W. Howland et al.   PLoS Pathogens

T Lymphocyte–Endothelial Interactions: Emerging Understanding of Trafficking and Antigen-Specific Immunity

(2015) Christopher V. Carman et al.   Frontiers in Immunology

Cutting Edge: Control of Mycobacterium tuberculosis Infection by a Subset of Lung Parenchyma-Homing CD4 T Cells

(2014) S. Sakai et al.   JOURNAL OF IMMUNOLOGY

Pathogenic Neisseria meningitidis utilizes CD147 for vascular colonization

(2014) Sandra C Bernard et al.   NATURE MEDICINE

West Nile Virus-Induced Cell Adhesion Molecules on Human Brain Microvascular Endothelial Cells Regulate Leukocyte Adhesion and Modulate Permeability of the In Vitro Blood-Brain Barrier Model

(2014) Kelsey Roe et al.   PLoS One

The gut microbiota influences blood-brain barrier permeability in mice

(2014) V. Braniste et al.   Science Translational Medicine

The lane to the brain: how African trypanosomes invade the CNS

(2014) Stefan Mogk et al.   TRENDS IN PARASITOLOGY

Shear Forces Enhance Toxoplasma gondii Tachyzoite Motility on Vascular Endothelium

(2014) K. S. Harker et al.   mBio

Antigen capture and archiving by lymphatic endothelial cells following vaccination or viral infection

(2014) Beth A. Tamburini et al.   Nature Communications

IL-6 trans-Signaling-Dependent Rapid Development of Cytotoxic CD8+ T Cell Function

(2014) Jan P. Böttcher et al.   Cell Reports

Persistent C. pneumoniae infection in atherosclerotic lesions: rethinking the clinical trials

(2014) Lee Ann Campbell et al.   Frontiers in Cellular and Infection Microbiology

Nr4a1-Dependent Ly6Clow Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal

(2013) Leo M. Carlin et al.   CELL

Real-time imaging ofToxoplasma-infected human monocytes under fluidic shear stress reveals rapid translocation of intracellular parasites across endothelial barriers

(2013) Norikiyo Ueno et al.   CELLULAR MICROBIOLOGY

Molecular Signatures of Tissue-Specific Microvascular Endothelial Cell Heterogeneity in Organ Maintenance and Regeneration

(2013) Daniel J. Nolan et al.   DEVELOPMENTAL CELL

Cryptococcus neoformans Promotes Its Transmigration into the Central Nervous System by Inducing Molecular and Cellular Changes in Brain Endothelial Cells

(2013) Kiem Vu et al.   INFECTION AND IMMUNITY

CD40 Induces Anti-Toxoplasma gondii Activity in Nonhematopoietic Cells Dependent on Autophagy Proteins

(2013) Jennifer Van Grol et al.   INFECTION AND IMMUNITY

West Nile virus infection and immunity

(2013) Mehul S. Suthar et al.   NATURE REVIEWS MICROBIOLOGY

Tissue factor pathway inhibitor-alpha inhibits prothrombinase during the initiation of blood coagulation

(2013) J. P. Wood et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Meningococcal disease and the complement system

(2013) Lisa A Lewis et al.   Virulence

Brain Inositol Is a Novel Stimulator for Promoting Cryptococcus Penetration of the Blood-Brain Barrier

(2013) Tong-Bao Liu et al.   PLoS Pathogens

Functional Vascular Endothelium Derived from Human Induced Pluripotent Stem Cells

(2013) William J. Adams et al.   Stem Cell Reports

Cryptococcus neoformansphospholipase B1 activates host cell Rac1 for traversal across the blood-brain barrier

(2012) Ravi Maruvada et al.   CELLULAR MICROBIOLOGY

Hyaluronic Acid Receptor CD44 Deficiency Is Associated with Decreased Cryptococcus neoformansBrain Infection

(2012) Ambrose Jong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice

(2012) Helge Frebel et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Endothelial Cells Elicit Immune-Enhancing Responses to Dengue Virus Infection

(2012) N. A. Dalrymple et al.   JOURNAL OF VIROLOGY

Early Invasion of Brain Parenchyma by African Trypanosomes

(2012) Ute Frevert et al.   PLoS One

A Decade of Imaging Cellular Motility and Interaction Dynamics in the Immune System

(2012) R. N. Germain et al.   SCIENCE

Essential role of RIG-I in the activation of endothelial cells by dengue virus

(2012) Thaís Moraes da Conceição et al.   VIROLOGY

Endothelial Cells Are Central Orchestrators of Cytokine Amplification during Influenza Virus Infection

(2011) John R. Teijaro et al.   CELL

Invasion ofCryptococcus neoformansinto Human Brain Microvascular Endothelial Cells Is Mediated through the Lipid Rafts-Endocytic Pathway via the Dual Specificity Tyrosine Phosphorylation-regulated Kinase 3 (DYRK3)

(2011) Sheng-He Huang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blood-brain barrier invasion by Cryptococcus neoformans is enhanced by functional interactions with plasmin

(2011) J. Stie et al.   MICROBIOLOGY-SGM

Endothelium—role in regulation of coagulation and inflammation

(2011) Victor W. M. van Hinsbergh   Seminars in Immunopathology

Meningococcus Hijacks a β2-Adrenoceptor/β-Arrestin Pathway to Cross Brain Microvasculature Endothelium

(2010) Mathieu Coureuil et al.   CELL

The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells

(2010) Yuefeng Tang et al.   GENESIS

Host-cell interactions with pathogenicRickettsiaspecies

(2009) Sanjeev K Sahni et al.   Future Microbiology

Activity of trypanosome lytic factor: a novel component of innate immunity

(2009) Russell Thomson et al.   Future Microbiology

Dynamics of T Cell, Antigen-Presenting Cell, and Pathogen Interactions during Recall Responses in the Lymph Node

(2009) Tatyana Chtanova et al.   IMMUNITY

Organ- and endotheliotropism of Nipah virus infections in vivo and in vitro

(2009) james Neufeld et al.   THROMBOSIS AND HAEMOSTASIS

West Nile virus infection modulates human brain microvascular endothelial cells tight junction proteins and cell adhesion molecules: Transmigration across the in vitro blood-brain barrier

(2009) Saguna Verma et al.   VIROLOGY

Protease Activated Receptor Signaling Is Required for African Trypanosome Traversal of Human Brain Microvascular Endothelial Cells

(2009) Dennis J. Grab et al.   PLoS Neglected Tropical Diseases

Yersinia enterocolitica Targets Cells of the Innate and Adaptive Immune System by Injection of Yops in a Mouse Infection Model

(2009) Martin Köberle et al.   PLoS Pathogens

Involvement of human CD44 during Cryptococcus neoformans infection of brain microvascular endothelial cells

(2008) Ambrose Jong et al.   CELLULAR MICROBIOLOGY

Polarized response of endothelial cells to invasion byAspergillus fumigatus

(2008) Yasuki Kamai et al.   CELLULAR MICROBIOLOGY

PfEMP1: An antigen that plays a key role in the pathogenicity and immune evasion of the malaria parasite Plasmodium falciparum

(2008) Noa D. Pasternak et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis

(2008) Jiyun V. Kim et al.   NATURE

Emerging and re-emerging rickettsioses: endothelial cell infection and early disease events

(2008) David H. Walker et al.   NATURE REVIEWS MICROBIOLOGY

Complement evasion by human pathogens

(2008) John D. Lambris et al.   NATURE REVIEWS MICROBIOLOGY

Infection of Endothelial Cells with VirulentRickettsia prowazekiiIncreases the Transmigration of Leukocytes

(2007) Yassina Bechah et al.   JOURNAL OF INFECTIOUS DISEASES