CD8+ T Cells Induce Fatal Brainstem Pathology during Cerebral Malaria via Luminal Antigen-Specific Engagement of Brain Vasculature

Access of protective antiviral antibody to neuronal tissues requires CD4 T-cell help

(2016) Norifumi Iijima et al.   NATURE

The pathogenesis of pediatric cerebral malaria: eye exams, autopsies, and neuroimaging

(2015) Terrie E. Taylor et al.   Annals of the New York Academy of Sciences

Therapeutic antiviral T cells noncytopathically clear persistently infected microglia after conversion into antigen-presenting cells

(2015) Jasmin Herz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Quantitative Assessment of Multiorgan Sequestration of Parasites in Fatal Pediatric Cerebral Malaria

(2015) Danny A. Milner et al.   JOURNAL OF INFECTIOUS DISEASES

Brain Swelling and Death in Children with Cerebral Malaria

(2015) Karl B. Seydel et al.   NEW ENGLAND JOURNAL OF MEDICINE

Specific Depletion of Ly6Chi Inflammatory Monocytes Prevents Immunopathology in Experimental Cerebral Malaria

(2015) Beatrix Schumak et al.   PLoS One

Spreading depolarization in the brainstem mediates sudden cardiorespiratory arrest in mouse SUDEP models

(2015) Isamu Aiba et al.   Science Translational Medicine

Inhibiting the Mammalian Target of Rapamycin Blocks the Development of Experimental Cerebral Malaria

(2015) Emile B. Gordon et al.   mBio

Dietary restriction protects against experimental cerebral malaria via leptin modulation and T-cell mTORC1 suppression

(2015) Pedro Mejia et al.   Nature Communications

Activated Brain Endothelial Cells Cross-Present Malaria Antigen

(2015) Shanshan W. Howland et al.   PLoS Pathogens

Perivascular Arrest of CD8+ T Cells Is a Signature of Experimental Cerebral Malaria

(2015) Tovah N. Shaw et al.   PLoS Pathogens

Olfactory Plays a Key Role in Spatiotemporal Pathogenesis of Cerebral Malaria

(2014) Hong Zhao et al.   Cell Host & Microbe

Granzyme B Promotes Cytotoxic Lymphocyte Transmigration via Basement Membrane Remodeling

(2014) Monica D. Prakash et al.   IMMUNITY

The Subcellular Location of Ovalbumin in Plasmodium berghei Blood Stages Influences the Magnitude of T-Cell Responses

(2014) Jing-Wen Lin et al.   INFECTION AND IMMUNITY

Endothelial Glycocalyx on Brain Endothelial Cells is Lost in Experimental Cerebral Malaria

(2014) Casper Hempel et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Chemokine Gene Expression during Fatal Murine Cerebral Malaria and Protection Due to CXCR3 Deficiency

(2014) J. Miu et al.   JOURNAL OF IMMUNOLOGY

Development of an Immunologically Tolerated Combination of Fluorescent Proteins for In vivo Two-photon Imaging

(2014) Selamawit Gossa et al.   Scientific Reports

Real-Time Imaging Reveals the Dynamics of Leukocyte Behaviour during Experimental Cerebral Malaria Pathogenesis

(2014) Saparna Pai et al.   PLoS Pathogens

Experimental Cerebral Malaria Pathogenesis—Hemodynamics at the Blood Brain Barrier

(2014) Adéla Nacer et al.   PLoS Pathogens

Loss of endothelial protein C receptors links coagulation and inflammation to parasite sequestration in cerebral malaria in African children

(2013) C. A. Moxon et al.   BLOOD

CXCL4 and CXCL10 Predict Risk of Fatal Cerebral Malaria

(2013) Nana O. Wilson et al.   DISEASE MARKERS

Brain microvessel cross-presentation is a hallmark of experimental cerebral malaria

(2013) Shanshan W. Howland et al.   EMBO Molecular Medicine

Prognostic indicators in adults hospitalized with falciparum malaria in Western Thailand

(2013) Paul N Newton et al.   MALARIA JOURNAL

Severe malaria is associated with parasite binding to endothelial protein C receptor

(2013) Louise Turner et al.   NATURE

CXCL10 Gene Promoter Polymorphism -1447A>G Correlates with Plasma CXCL10 Levels and is Associated with Male Susceptibility to Cerebral Malaria

(2013) Nana Wilson et al.   PLoS One

Protective role of brain water channel AQP4 in murine cerebral malaria

(2013) D. Promeneur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cerebral malaria pathogenesis: revisiting parasite and host contributions

(2012) Georges Emile Raymond Grau et al.   Future Microbiology

IFN- -Producing CD4+ T Cells Promote Experimental Cerebral Malaria by Modulating CD8+ T Cell Accumulation within the Brain

(2012) A. Villegas-Mendez et al.   JOURNAL OF IMMUNOLOGY

Novel 3D analysis of Claudin-5 reveals significant endothelial heterogeneity among CNS microvessels

(2012) Debayon Paul et al.   MICROVASCULAR RESEARCH

A restricted subset of var genes mediates adherence of Plasmodium falciparum-infected erythrocytes to brain endothelial cells

(2012) M. Avril et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroimmunological Blood Brain Barrier Opening in Experimental Cerebral Malaria

(2012) Adela Nacer et al.   PLoS Pathogens

The Neuropathology of Fatal Cerebral Malaria in Malawian Children

(2011) Katerina Dorovini-Zis et al.   AMERICAN JOURNAL OF PATHOLOGY

Migration of cytotoxic lymphocytes in cell cycle permits local MHC I–dependent control of division at sites of viral infection

(2011) Silvia S. Kang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Critical role of the neutrophil-associated high-affinity receptor for IgE in the pathogenesis of experimental cerebral malaria

(2011) Adeline Porcherie et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Granzyme B Expression by CD8+ T Cells Is Required for the Development of Experimental Cerebral Malaria

(2011) A. Haque et al.   JOURNAL OF IMMUNOLOGY

CD8+ T Cells and IFN-γ Mediate the Time-Dependent Accumulation of Infected Red Blood Cells in Deep Organs during Experimental Cerebral Malaria

(2011) Carla Claser et al.   PLoS One

Association of HLA alleles with Plasmodium falciparum severity in Malian children

(2011) K. E. Lyke et al.   TISSUE ANTIGENS

A rapid and robust tri-color flow cytometry assay for monitoring malaria parasite development

(2011) Benoît Malleret et al.   Scientific Reports

Reproducible Isolation of Lymph Node Stromal Cells Reveals Site-Dependent Differences in Fibroblastic Reticular Cells

(2011) Anne L. Fletcher et al.   Frontiers in Immunology

Thinned-skull cranial window technique for long-term imaging of the cortex in live mice

(2010) Guang Yang et al.   Nature Protocols

A Rapid Murine Coma and Behavior Scale for Quantitative Assessment of Murine Cerebral Malaria

(2010) Ryan W. Carroll et al.   PLoS One

Expression of Chemokines and Their Receptors by Human Brain Endothelium: Implications for Multiple Sclerosis

(2009) Eve A. Subileau et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

IP-10-Mediated T Cell Homing Promotes Cerebral Inflammation over Splenic Immunity to Malaria Infection

(2009) Catherine Q. Nie et al.   PLoS Pathogens

CXCR3 determines strain susceptibility to murine cerebral malaria by mediating T lymphocyte migration toward IFN-γ-induced chemokines

(2008) Philippe E. Van den Steen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Plasma IP-10, apoptotic and angiogenic factors associated with fatal cerebral malaria in India

(2008) Vidhan Jain et al.   MALARIA JOURNAL

Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis

(2008) Jiyun V. Kim et al.   NATURE

Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8 + dendritic cells

(2008) R. J. Lundie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria

(2008) G. S. V. Campanella et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA