Endothelium—role in regulation of coagulation and inflammation

Protective cross talk between activated protein C and TNF signaling in vascular endothelial cells: implication of EPCR, noncanonical NF-κB, and ERK1/2 MAP kinases

(2011) Christophe Guitton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Functional architecture of Weibel-Palade bodies

(2011) K. M. Valentijn et al.   BLOOD

Factor VIIa bound to endothelial cell protein C receptor activates protease activated receptor-1 and mediates cell signaling and barrier protection

(2011) P. Sen et al.   BLOOD

Cell-Derived Microparticles in the Pathogenesis of Cardiovascular Disease

(2010) Maarten E. Tushuizen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Many Faces of Endothelial Microparticles

(2010) Françoise Dignat-George et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Thrombotic thrombocytopenic purpura directly linked with ADAMTS13 inhibition in the baboon (Papio ursinus)

(2010) H. B. Feys et al.   BLOOD

Endothelial-derived tissue factor pathway inhibitor regulates arterial thrombosis but is not required for development or hemostasis

(2010) T. A. White et al.   BLOOD

Shiga toxin B subunits induce VWF secretion by human endothelial cells and thrombotic microangiopathy in ADAMTS13-deficient mice

(2010) J. Huang et al.   BLOOD

Selective abrogation of the uPA-uPAR interaction in vivo reveals a novel role in suppression of fibrin-associated inflammation

(2010) B. M. Connolly et al.   BLOOD

Multigranular exocytosis of Weibel-Palade bodies in vascular endothelial cells

(2010) K. M. Valentijn et al.   BLOOD

Endothelium-derived but not platelet-derived protein disulfide isomerase is required for thrombus formation in vivo

(2010) R. Jasuja et al.   BLOOD

The Balance between von-Willebrand Factor and its Cleaving Protease ADAMTS13: Biomarker in Systemic Inflammation and Development of Organ Failure?

(2010) R. Claus et al.   CURRENT MOLECULAR MEDICINE

TRAF3 Controls Activation of the Canonical and Alternative NFκB by the Lymphotoxin Beta Receptor

(2010) Pradeep Bista et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activated protein C targets CD8+ dendritic cells to reduce the mortality of endotoxemia in mice

(2010) Edward Kerschen et al.   JOURNAL OF CLINICAL INVESTIGATION

The efficacy of activated protein C in murine endotoxemia is dependent on integrin CD11b

(2010) Chunzhang Cao et al.   JOURNAL OF CLINICAL INVESTIGATION

Antiphospholipid antibodies promote leukocyte–endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2

(2010) Sangeetha Ramesh et al.   JOURNAL OF CLINICAL INVESTIGATION

Vascular Responses to Hypoxia and Ischemia

(2009) Gregg L. Semenza   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Endogenous EPCR/aPC-PAR1 signaling prevents inflammation-induced vascular leakage and lethality

(2009) F. Niessen et al.   BLOOD

Activation of endothelial intrinsic NF- B pathway impairs protein C anticoagulation mechanism and promotes coagulation in endotoxemic mice

(2009) D. Song et al.   BLOOD

C-terminal ADAMTS-18 fragment induces oxidative platelet fragmentation, dissolves platelet aggregates, and protects against carotid artery occlusion and cerebral stroke

(2009) Z. Li et al.   BLOOD

Endothelial cell ADAMTS-13 and VWF: production, release, and VWF string cleavage

(2009) N. A. Turner et al.   BLOOD

Endothelial cell lumen and vascular guidance tunnel formation requires MT1-MMP-dependent proteolysis in 3-dimensional collagen matrices

(2009) A. N. Stratman et al.   BLOOD

Endogenous activated protein C limits cancer cell extravasation through sphingosine-1-phosphate receptor 1-mediated vascular endothelial barrier enhancement

(2009) G. L. Van Sluis et al.   BLOOD

The prototype endothelial marker PAL-E is a leukocyte trafficking molecule

(2009) J. Keuschnigg et al.   BLOOD

Regulation of Angiogenesis by Oxygen and Metabolism

(2009) Peter Fraisl et al.   DEVELOPMENTAL CELL

The urokinase receptor: Focused cell surface proteolysis, cell adhesion and signaling

(2009) Francesco Blasi et al.   FEBS LETTERS

ADAMTS13 Bound to Endothelial Cells Exhibits Enhanced Cleavage of von Willebrand Factor

(2009) Anthony N. Vomund et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effect of Intravenous FX06 as an Adjunct to Primary Percutaneous Coronary Intervention for Acute ST-Segment Elevation Myocardial Infarction

(2009) Dan Atar et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Soluble Thrombomodulin Protects Ischemic Kidneys

(2009) A. A. Sharfuddin et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Inflammatory mechanisms in atherosclerosis

(2009) G. K. HANSSON   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

von Willebrand factor assembly and secretion

(2009) J. E. SADLER   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

The many faces of tissue factor

(2009) N. MACKMAN   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Riboflavin kinase couples TNF receptor 1 to NADPH oxidase

(2009) Benjamin Yazdanpanah et al.   NATURE

Thrombomodulin Mutations in Atypical Hemolytic–Uremic Syndrome

(2009) Mieke Delvaeye et al.   NEW ENGLAND JOURNAL OF MEDICINE

Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1

(2009) Gregg L. Semenza   PHYSIOLOGY

Caveolae are required for protease-selective signaling by protease-activated receptor-1

(2009) A. Russo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural organization of Weibel-Palade bodies revealed by cryo-EM of vitrified endothelial cells

(2009) J. A. Berriman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysophosphatidic acid stimulates thrombomodulin lectin-like domain shedding in human endothelial cells

(2008) Hua-Lin Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Basal secretion of von Willebrand factor from human endothelial cells

(2008) J. P. Giblin et al.   BLOOD

Caveolin-1-dependent apoptosis induced by fibrin degradation products

(2008) Y.-H. Guo et al.   BLOOD

Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity

(2008) Wineke Bakker et al.   CELL AND TISSUE RESEARCH

Fibrin: A Natural Biodegradable Scaffold in Vascular Tissue Engineering

(2008) Faisal M. Shaikh et al.   CELLS TISSUES ORGANS

Divergent roles of endothelial NF-κB in multiple organ injury and bacterial clearance in mouse models of sepsis

(2008) Xiaobing Ye et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ADAMTS13: a new link between thrombosis and inflammation

(2008) Anil K. Chauhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseases

(2008) J. M. van Gils et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Inflammatory cytokines inhibit ADAMTS13 synthesis in hepatic stellate cells and endothelial cells

(2008) W. J. CAO et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation

(2008) Frank Niessen et al.   NATURE

Molecular basis of ADAMTS13 dysfunction in thrombotic thrombocytopenic purpura

(2008) Minola Manea et al.   PEDIATRIC NEPHROLOGY

ADAMTS13 binds to CD36: a potential mechanism for platelet and endothelial localization of ADAMTS13

(2008) Amanda K. Davis et al.   TRANSFUSION

Platelet-VWF complexes are preferred substrates of ADAMTS13 under fluid shear stress

(2007) K. Shim et al.   BLOOD