Antigen archiving by lymph node stroma: A novel function for the lymphatic endothelium

Fibroblastic Reticular Cells: Organization and Regulation of the T Lymphocyte Life Cycle

(2015) Flavian D. Brown et al.   JOURNAL OF IMMUNOLOGY

Roles of lymphatic endothelial cells expressing peripheral tissue antigens in CD4 T-cell tolerance induction

(2015) Sherin J. Rouhani et al.   Nature Communications

Inflammatory lymphangiogenesis: cellular mediators and functional implications

(2014) Kar Wai Tan et al.   ANGIOGENESIS

Exosomes and other extracellular vesicles in host-pathogen interactions

(2014) J. S. Schorey et al.   EMBO REPORTS

Oral Tolerance Can Be Established via Gap Junction Transfer of Fed Antigens from CX3CR1+ Macrophages to CD103+ Dendritic Cells

(2014) Elisa Mazzini et al.   IMMUNITY

Emerging roles of lymphatic endothelium in regulating adaptive immunity

(2014) Catherine M. Card et al.   JOURNAL OF CLINICAL INVESTIGATION

Memory CD8+T cells exhibit increased antigen threshold requirements for recall proliferation

(2014) Erin R. Mehlhop-Williams et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lymph node stromal cells acquire peptide–MHCII complexes from dendritic cells and induce antigen-specific CD4+T cell tolerance

(2014) Juan Dubrot et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Organizer-Like Reticular Stromal Cell Layer Common to Adult Secondary Lymphoid Organs

(2014) T. Katakai et al.   JOURNAL OF IMMUNOLOGY

Prolonged Antigen Presentation following an Acute Virus Infection Requires Direct and Then Cross-Presentation

(2014) Erica L. Heipertz et al.   JOURNAL OF IMMUNOLOGY

Steady-State Antigen Scavenging, Cross-Presentation, and CD8+ T Cell Priming: A New Role for Lymphatic Endothelial Cells

(2014) S. Hirosue et al.   JOURNAL OF IMMUNOLOGY

Tim4- and MerTK-Mediated Engulfment of Apoptotic Cells by Mouse Resident Peritoneal Macrophages

(2014) C. Nishi et al.   MOLECULAR AND CELLULAR BIOLOGY

Dendritic cells control fibroblastic reticular network tension and lymph node expansion

(2014) Sophie E. Acton et al.   NATURE

The CLEC-2–podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture

(2014) Jillian L Astarita et al.   NATURE IMMUNOLOGY

B cell homeostasis and follicle confines are governed by fibroblastic reticular cells

(2014) Viviana Cremasco et al.   NATURE IMMUNOLOGY

Tolerogenic Properties of Lymphatic Endothelial Cells Are Controlled by the Lymph Node Microenvironment

(2014) Jarish N. Cohen et al.   PLoS One

Dendritic cell subsets require cis-activation for cytotoxic CD8 T-cell induction

(2014) A Nicole Desch et al.   Nature Communications

Antigen capture and archiving by lymphatic endothelial cells following vaccination or viral infection

(2014) Beth A. Tamburini et al.   Nature Communications

Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage

(2013) M. Iolyeva et al.   BLOOD

Endocytosis and Recycling of Immune Complexes by Follicular Dendritic Cells Enhances B Cell Antigen Binding and Activation

(2013) Balthasar A. Heesters et al.   IMMUNITY

Structural insight on the recognition of surface-bound opsonins by the integrin I domain of complement receptor 3

(2013) G. Bajic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IL-7-producing stromal cells are critical for lymph node remodeling

(2012) L. Onder et al.   BLOOD

Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells

(2012) E. F. Tewalt et al.   BLOOD

Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2

(2012) Sophie E. Acton et al.   IMMUNITY

Stromal and hematopoietic cells in secondary lymphoid organs: partners in immunity

(2012) Deepali Malhotra et al.   IMMUNOLOGICAL REVIEWS

Transcriptional profiling of stroma from inflamed and resting lymph nodes defines immunological hallmarks

(2012) Deepali Malhotra et al.   NATURE IMMUNOLOGY

Memory CD4+ T-cell-mediated protection depends on secondary effectors that are distinct from and superior to primary effectors

(2012) T. M. Strutt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VEGF-C Promotes Immune Tolerance in B16 Melanomas and Cross-Presentation of Tumor Antigen by Lymph Node Lymphatics

(2012) Amanda W. Lund et al.   Cell Reports

Lymphatic endothelial cells - key players in regulation of tolerance and immunity

(2012) Eric F. Tewalt et al.   Frontiers in Immunology

Stromal Cell–Immune Cell Interactions

(2011) Ramon Roozendaal et al.   Annual Review of Immunology

Functional architecture of Weibel-Palade bodies

(2011) K. M. Valentijn et al.   BLOOD

T Lymphocytes Negatively Regulate Lymph Node Lymphatic Vessel Formation

(2011) Raghu P. Kataru et al.   IMMUNITY

CD103+pulmonary dendritic cells preferentially acquire and present apoptotic cell–associated antigen

(2011) A. Nicole Desch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Follicular dendritic cells help establish follicle identity and promote B cell retention in germinal centers

(2011) Xiaoming Wang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

DC mobilization from the skin requires docking to immobilized CCL21 on lymphatic endothelium and intralymphatic crawling

(2011) Orna Tal et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cross-dressed dendritic cells drive memory CD8+ T-cell activation after viral infection

(2011) Linda M. Wakim et al.   NATURE

A Crystal Structure of the Complex Between Human Complement Receptor 2 and Its Ligand C3d

(2011) J. M. H. van den Elsen et al.   SCIENCE

T cell responses during influenza infection: getting and keeping control

(2011) Taeg S. Kim et al.   TRENDS IN IMMUNOLOGY

Characterizing follicular dendritic cells: A progress report

(2010) Adriano Aguzzi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immobilized Chemokine Fields and Soluble Chemokine Gradients Cooperatively Shape Migration Patterns of Dendritic Cells

(2010) Kathrin Schumann et al.   IMMUNITY

Acquisition and presentation of follicular dendritic cell–bound antigen by lymph node–resident dendritic cells

(2010) Megan L. McCloskey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antigen persistence and the control of local T cell memory by migrant respiratory dendritic cells after acute virus infection

(2010) Taeg S. Kim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The route of priming influences the ability of respiratory virus–specific memory CD8+T cells to be activated by residual antigen

(2010) Shiki Takamura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lymph node–resident lymphatic endothelial cells mediate peripheral tolerance via Aire-independent direct antigen presentation

(2010) Jarish N. Cohen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lymph node cortical sinus organization and relationship to lymphocyte egress dynamics and antigen exposure

(2010) I. L. Grigorova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Critical role of CD11b+ macrophages and VEGF in inflammatory lymphangiogenesis, antigen clearance, and inflammation resolution

(2009) R. P. Kataru et al.   BLOOD

B Lymphocytes Exit Lymph Nodes through Cortical Lymphatic Sinusoids by a Mechanism Independent of Sphingosine-1-Phosphate-Mediated Chemotaxis

(2009) Rajesh K. Sinha et al.   IMMUNITY

Visualizing B cell capture of cognate antigen from follicular dendritic cells

(2009) Kazuhiro Suzuki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

(2009) Trung H.M. Pham et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immune complex relay by subcapsular sinus macrophages and noncognate B cells drives antibody affinity maturation

(2009) Tri Giang Phan et al.   NATURE IMMUNOLOGY

The conduit system of the lymph node

(2008) R. Roozendaal et al.   INTERNATIONAL IMMUNOLOGY

Characterization of the Follicular Dendritic Cell Reservoir of Human Immunodeficiency Virus Type 1

(2008) B. F. Keele et al.   JOURNAL OF VIROLOGY

Restoration of lymphoid organ integrity through the interaction of lymphoid tissue–inducer cells with stroma of the T cell zone

(2008) Elke Scandella et al.   NATURE IMMUNOLOGY