Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells
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Title
Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells
Authors
Keywords
Cannabidiol, Memory T cells, LAG3, CD69, EGR2, T cell anergy
Journal
Journal of Neuroinflammation
Volume 12, Issue 1, Pages 52
Publisher
Springer Nature
Online
2015-03-14
DOI
10.1186/s12974-015-0273-0
References
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Note: Only part of the references are listed.- CD69+CD4+CD25- T Cells, a New Subset of Regulatory T Cells, Suppress T Cell Proliferation through Membrane-Bound TGF- 1
- (2014) Y. Han et al. JOURNAL OF IMMUNOLOGY
- Regulatory T Cells Inhibit Dendritic Cells by Lymphocyte Activation Gene-3 Engagement of MHC Class II
- (2014) Bitao Liang et al. JOURNAL OF IMMUNOLOGY
- In Vitro Induced Regulatory T Cells Are Unique from Endogenous Regulatory T Cells and Effective at Suppressing Late Stages of Ongoing Autoimmunity
- (2014) Thanh-Long M. Nguyen et al. PLoS One
- Lymphocyte Activation Gene-3 (LAG-3) Negatively Regulates Environmentally-Induced Autoimmunity
- (2014) Vibha Jha et al. PLoS One
- Egr-2 transcription factor is required for Blimp-1-mediated IL-10 production in IL-27-stimulated CD4+T cells
- (2013) Yukiko Iwasaki et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- MHC class II–dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies
- (2013) Nicolas Molnarfi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cannabinoids Decrease the Th17 Inflammatory Autoimmune Phenotype
- (2013) Ewa Kozela et al. Journal of Neuroimmune Pharmacology
- Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells
- (2013) Nicola Gagliani et al. NATURE MEDICINE
- Regulatory T cell proliferative potential is impaired in human autoimmune disease
- (2013) Fortunata Carbone et al. NATURE MEDICINE
- Microarray and Pathway Analysis Reveal Distinct Mechanisms Underlying Cannabinoid-Mediated Modulation of LPS-Induced Activation of BV-2 Microglial Cells
- (2013) Ana Juknat et al. PLoS One
- Transiently Reduced PI3K/Akt Activity Drives the Development of Regulatory Function in Antigen-Stimulated Naïve T-Cells
- (2013) Eloho Etemire et al. PLoS One
- Roles of LAG3 and EGR2 in regulatory T cells
- (2012) Tomohisa Okamura et al. ANNALS OF THE RHEUMATIC DISEASES
- Cannabidiol for neurodegenerative disorders: important new clinical applications for this phytocannabinoid?
- (2012) Javier Fernández-Ruiz et al. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
- Signal Transduction via Cannabinoid Receptors
- (2012) George Dalton et al. CNS & Neurological Disorders-Drug Targets
- Cannabinoid Modulation of Neuroinflammatory Disorders
- (2012) Viviane M. Saito et al. Current Neuropharmacology
- Transcriptional regulator early growth response gene 2 (Egr2) is required for T cell anergy in vitro and in vivo
- (2012) Yan Zheng et al. JOURNAL OF EXPERIMENTAL MEDICINE
- B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6–producing B cells
- (2012) Tom A. Barr et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Early Growth Response Gene-2 Controls IL-17 Expression and Th17 Differentiation by Negatively Regulating Batf
- (2012) T. Miao et al. JOURNAL OF IMMUNOLOGY
- Induction and molecular signature of pathogenic TH17 cells
- (2012) Youjin Lee et al. NATURE IMMUNOLOGY
- Analysis of sirtuin 1 expression reveals a molecular explanation of IL-2-mediated reversal of T-cell tolerance
- (2012) B. Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Selective inhibition of CD4+ T-cell cytokine production and autoimmunity by BET protein and c-Myc inhibitors
- (2012) H. S. Bandukwala et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rationale of anti-CD19 immunotherapy: an option to target autoreactive plasma cells in autoimmunity
- (2012) Henrik E Mei et al. ARTHRITIS RESEARCH & THERAPY
- Cannabidiol inhibits pathogenic T cells, decreases spinal microglial activation and ameliorates multiple sclerosis-like disease in C57BL/6 mice
- (2011) Ewa Kozela et al. BRITISH JOURNAL OF PHARMACOLOGY
- PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
- (2011) Taku Okazaki et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Cutting Edge: Accelerated Autoimmune Diabetes in the Absence of LAG-3
- (2011) M. Bettini et al. JOURNAL OF IMMUNOLOGY
- Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5
- (2011) Xiang-Ping Yang et al. NATURE IMMUNOLOGY
- Role of Myeloid-Derived Suppressor Cells in Amelioration of Experimental Autoimmune Hepatitis Following Activation of TRPV1 Receptors by Cannabidiol
- (2011) Venkatesh L. Hegde et al. PLoS One
- CD69: An Unexpected Regulator of TH17 Cell-Driven Inflammatory Responses
- (2011) P. Martin et al. Science Signaling
- The Th1 life cycle: molecular control of IFN-γ to IL-10 switching
- (2011) Andrew Cope et al. TRENDS IN IMMUNOLOGY
- The CD4-like molecule LAG-3, biology and therapeutic applications
- (2010) Sophie Sierro et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- CD69 Association with Jak3/Stat5 Proteins Regulates Th17 Cell Differentiation
- (2010) P. Martin et al. MOLECULAR AND CELLULAR BIOLOGY
- Hyperactivation of nuclear factor of activated T cells 1 (NFAT1) in T cells attenuates severity of murine autoimmune encephalomyelitis
- (2010) S. Ghosh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cannabinoids as novel anti-inflammatory drugs
- (2009) Prakash Nagarkatti et al. Future Medicinal Chemistry
- Cannabinoids Δ9-Tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-activated NF-κB and Interferon-β/STAT Proinflammatory Pathways in BV-2 Microglial Cells
- (2009) Ewa Kozela et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Identification and characterization of IL-10/IFN-γ–producing effector-like T cells with regulatory function in human blood
- (2009) Barbara Häringer et al. JOURNAL OF EXPERIMENTAL MEDICINE
- CD69 Gene Is Differentially Regulated in T and B Cells by Evolutionarily Conserved Promoter-Distal Elements
- (2009) B. N. Vazquez et al. JOURNAL OF IMMUNOLOGY
- CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2
- (2009) T. Okamura et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Early growth response gene 2 (Egr-2) controls the self-tolerance of T cells and prevents the development of lupuslike autoimmune disease
- (2008) Bo Zhu et al. JOURNAL OF EXPERIMENTAL MEDICINE
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