MHC class II–dependent B cell APC function is required for induction of CNS autoimmunity independent of myelin-specific antibodies

Demyelinating Myelin Oligodendrocyte Glycoprotein-Specific Autoantibody Response Is Focused on One Dominant Conformational Epitope Region in Rodents

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Therapeutic Decisions in Multiple Sclerosis

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Astrocyte-specific deficiency of interleukin-6 and its receptor reveal specific roles in survival, body weight and behavior

(2012) Albert Quintana et al.   BRAIN BEHAVIOR AND IMMUNITY

Conditional DC depletion does not affect priming of encephalitogenic Th cells in EAE

(2012) Magnus Isaksson et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6–producing B cells

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Setting a research agenda for progressive multiple sclerosis: The International Collaborative on Progressive MS

(2012) Robert J Fox et al.   Multiple Sclerosis Journal

Follicular Helper CD4 T Cells (TFH)

(2011) Shane Crotty   Annual Review of Immunology

B cells in multiple sclerosis: connecting the dots

(2011) H-Christian von Büdingen et al.   CURRENT OPINION IN IMMUNOLOGY

Ocrelizumab in relapsing-remitting multiple sclerosis: a phase 2, randomised, placebo-controlled, multicentre trial

(2011) Ludwig Kappos et al.   LANCET

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

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B-cell activation influences T-cell polarization and outcome of anti-CD20 B-cell depletion in central nervous system autoimmunity

(2010) Martin S. Weber et al.   ANNALS OF NEUROLOGY

Follicular Helper T Cell Differentiation Requires Continuous Antigen Presentation that Is Independent of Unique B Cell Signaling

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Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

(2009) Amit Bar-Or et al.   ANNALS OF NEUROLOGY

Depletion of B Lymphocytes From Cerebral Perivascular Spaces by Rituximab

(2009) Maria del Pilar Martin et al.   ARCHIVES OF NEUROLOGY

Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells

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Rituximab in relapsing-remitting multiple sclerosis: A 72-week, open-label, phase I trial

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Reversal of axonal loss and disability in a mouse model of progressive multiple sclerosis

(2008) Alexandre S. Basso et al.   JOURNAL OF CLINICAL INVESTIGATION

B-Cell Depletion with Rituximab in Relapsing–Remitting Multiple Sclerosis

(2008) Stephen L. Hauser et al.   NEW ENGLAND JOURNAL OF MEDICINE