PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice

PD-1 deficiency results in the development of fatal myocarditis in MRL mice

(2010) Jian Wang et al.   INTERNATIONAL IMMUNOLOGY

Deficiency in activation-induced cytidine deaminase promotes systemic autoimmunity inlprmice on a C57BL/6 background

(2009) L. Chen et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Identification of QTLs that modify peripheral neuropathy in NOD.H2b-Pdcd1-/- mice

(2009) F. Jiang et al.   INTERNATIONAL IMMUNOLOGY

On the role of the inhibitory receptor LAG-3 in acute and chronic LCMV infection

(2009) Kirsten Richter et al.   INTERNATIONAL IMMUNOLOGY

Functionally Distinct LAG-3 and PD-1 Subsets on Activated and Chronically Stimulated CD8 T Cells

(2009) J. F. Grosso et al.   JOURNAL OF IMMUNOLOGY

LAG-3 Regulates Plasmacytoid Dendritic Cell Homeostasis

(2009) C. J. Workman et al.   JOURNAL OF IMMUNOLOGY

Preferential Generation of Follicular B Helper T Cells from Foxp3+ T Cells in Gut Peyer's Patches

(2009) M. Tsuji et al.   SCIENCE

PD-1 and Its Ligands in Tolerance and Immunity

(2008) Mary E. Keir et al.   Annual Review of Immunology

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

(2008) Shawn D Blackburn et al.   NATURE IMMUNOLOGY

Activation-Induced Cytidine Deaminase Deficiency Causes Organ-Specific Autoimmune Disease

(2008) Koji Hase et al.   PLoS One

PD-1 deficiency reveals various tissue-specific autoimmunity by H-2b and dose-dependent requirement of H-2g7 for diabetes in NOD mice

(2008) T. Yoshida et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CTLA-4 Control over Foxp3+ Regulatory T Cell Function

(2008) K. Wing et al.   SCIENCE