Reactive oxygen species, Nox and angiotensin II in angiogenesis: implications for retinopathy

The cross-talk between NF-κB and HIF-1: further evidence for a significant liaison: Figure 1

(2015) Agnes Görlach et al.   BIOCHEMICAL JOURNAL

Rate of serious adverse effects in a series of bevacizumab and ranibizumab injections

(2013) Sanjay Sharma et al.   CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE

Angiotensin II stimulates superoxide production in the thick ascending limb by activating NOX4

(2012) Katherine J. Massey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Angiotensin II enhances AT1-Nox1 binding and stimulates arterial smooth muscle cell migration and proliferation through AT1, Nox1, and interleukin-18

(2012) Anthony J. Valente et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Oxidative stress, Noxs, and hypertension: Experimental evidence and clinical controversies

(2012) Augusto C. Montezano et al.   ANNALS OF MEDICINE

NADPH Oxidases as Regulators of Tumor Angiogenesis: Current and Emerging Concepts

(2012) Sanja Coso et al.   ANTIOXIDANTS & REDOX SIGNALING

Targeting NOX enzymes in the central nervous system: therapeutic opportunities

(2012) Silvia Sorce et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

ROS homeostasis during development: an evolutionary conserved strategy

(2012) Jos H. M. Schippers et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

(2012) Katrin Schröder et al.   CIRCULATION RESEARCH

Global Prevalence and Major Risk Factors of Diabetic Retinopathy

(2012) J. W. Y. Yau et al.   DIABETES CARE

Update on animal models of diabetic retinopathy: from molecular approaches to mice and higher mammals

(2012) R. Robinson et al.   Disease Models & Mechanisms

Puerarin inhibits the retinal pericyte apoptosis induced by advanced glycation end products in vitro and in vivo by inhibiting NADPH oxidase-related oxidative stress

(2012) Junghyun Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Neovascularization Is Attenuated With Aldosterone Synthase Inhibition in Rats With Retinopathy

(2012) Devy Deliyanti et al.   HYPERTENSION

The HIF1 target gene NOX2 promotes angiogenesis through urotensin-II

(2012) Isabel Diebold et al.   JOURNAL OF CELL SCIENCE

Mineralocorticoid receptor is involved in rat and human ocular chorioretinopathy

(2012) Min Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

CIKS (Act1 or TRAF3IP2) mediates Angiotensin-II-induced Interleukin-18 expression, and Nox2-dependent cardiomyocyte hypertrophy

(2012) Anthony J. Valente et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Angiotensin II induces DNA damage via AT1 receptor and NADPH oxidase isoform Nox4

(2012) G. Fazeli et al.   MUTAGENESIS

The emerging role of ROS-generating NADPH oxidase NOX4 in DNA-damage responses

(2012) Urbain Weyemi et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Pathological neoangiogenesis depends on oxidative stress regulation by ATM

(2012) Yuji Okuno et al.   NATURE MEDICINE

Reduction of Retinopathy of Prematurity in Extremely Low Gestational Age Newborns Treated with Recombinant Human Cu/Zn Superoxide Dismutase

(2012) Richard B. Parad et al.   Neonatology

The retinal renin–angiotensin system: Roles of angiotensin II and aldosterone

(2012) Jennifer L. Wilkinson-Berka et al.   PEPTIDES

Time-Dependent Stabilization of Hypoxia Inducible Factor-1α by Different Intracellular Sources of Reactive Oxygen Species

(2012) Maura Calvani et al.   PLoS One

Interleukin-6 promotes destabilized angiogenesis by modulating angiopoietin expression in rheumatoid arthritis

(2012) K. Kayakabe et al.   RHEUMATOLOGY

Prolyl Hydroxylase Domain Protein 2 (PHD2) Mediates Oxygen-Induced Retinopathy in Neonatal Mice

(2011) Li-Juan Duan et al.   AMERICAN JOURNAL OF PATHOLOGY

Nuclear Factor-κB: a Key Regulator in Health and Disease of Lungs

(2011) Sanjay Batra et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

NADPH Oxidase 4 Promotes Endothelial Angiogenesis Through Endothelial Nitric Oxide Synthase Activation

(2011) Siobhan M. Craige et al.   CIRCULATION

Pathophysiological Roles of NADPH Oxidase/Nox Family Proteins in the Vascular System

(2011) Tetsuro Ago et al.   CIRCULATION JOURNAL

The Nox Family of NADPH Oxidases: Friend or Foe of the Vascular System?

(2011) Ina Takac et al.   CURRENT HYPERTENSION REPORTS

Anti-Angiogenesis Drugs in Diabetic Retinopathy

(2011) V. Swetha E. Jeganathan   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

The formation of an angiogenic astrocyte template is regulated by the neuroretina in a HIF-1-dependent manner

(2011) Ayako Nakamura-Ishizu et al.   DEVELOPMENTAL BIOLOGY

Retinal Microglial Activation and Inflammation Induced by Amadori-Glycated Albumin in a Rat Model of Diabetes

(2011) A. S. Ibrahim et al.   DIABETES

Intervention With an Erythropoietin-Derived Peptide Protects Against Neuroglial and Vascular Degeneration During Diabetic Retinopathy

(2011) Carmel M. McVicar et al.   DIABETES

Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology

(2011) A. K. Berner et al.   DIABETOLOGIA

Aliskiren reduces vascular pathology in diabetic retinopathy and oxygen-induced retinopathy in the transgenic (mRen-2)27 rat

(2011) J. L. Wilkinson-Berka et al.   DIABETOLOGIA

Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo

(2011) Alison C. Brewer et al.   FREE RADICAL BIOLOGY AND MEDICINE

T Regulatory Lymphocytes Prevent Aldosterone-Induced Vascular Injury

(2011) Daniel A. Kasal et al.   HYPERTENSION

Anti-inflammatory therapy for diabetic retinopathy

(2011) Wenbo Zhang et al.   Immunotherapy

The E-loop Is Involved in Hydrogen Peroxide Formation by the NADPH Oxidase Nox4

(2011) Ina Takac et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NADPH oxidase 4 mediates upregulation of type 4 phosphodiesterases in human endothelial cells

(2011) Saima Muzaffar et al.   JOURNAL OF CELLULAR PHYSIOLOGY

IL-8-mediated angiogenic responses of endothelial cells to lipid antigen activation of iNKT cells depend on EGFR transactivation

(2011) Emmanouil Kyriakakis et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Astroglial NF-κB mediates oxidative stress by regulation of NADPH oxidase in a model of retinal ischemia reperfusion injury

(2011) David J. Barakat et al.   JOURNAL OF NEUROCHEMISTRY

Retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina

(2011) Viswanathan Sivakumar et al.   JOURNAL OF PATHOLOGY

Differential regulation of Nox1, Nox2 and Nox4 in vascular smooth muscle cells from WKY and SHR

(2011) Ana M. Briones et al.   Journal of the American Society of Hypertension

Bone marrow-derived monocyte lineage cells recruited by MIP-1β promote physiological revascularization in mouse model of oxygen-induced retinopathy

(2011) Keijiro Ishikawa et al.   LABORATORY INVESTIGATION

Targeting Vascular NADPH Oxidase 1 Blocks Tumor Angiogenesis through a PPARα Mediated Mechanism

(2011) Sarah Garrido-Urbani et al.   PLoS One

Inflammation in diabetic retinopathy

(2011) Johnny Tang et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Perinatal infection, inflammation, and retinopathy of prematurity

(2011) Jennifer Lee et al.   Seminars in Fetal & Neonatal Medicine

NOX2 is the primary source of angiotensin II-induced superoxide in the macula densa

(2010) Yiling Fu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Hepatocyte Growth Factor Induces a Proangiogenic Phenotype and Mobilizes Endothelial Progenitor Cells by Activating Nox2

(2010) Katrin Schröder et al.   ANTIOXIDANTS & REDOX SIGNALING

Protein kinase C-δ is involved in induction of NOX1 gene expression by aldosterone in rat vascular smooth muscle cells

(2010) Haiyan Wei et al.   BIOCHEMISTRY-MOSCOW

Hypoxia and mitochondrial oxidative metabolism

(2010) Giancarlo Solaini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Pigment epithelium-derived factor inhibits advanced glycation end products-induced retinal vascular permeability

(2010) Sardarpasha Sheikpranbabu et al.   BIOCHIMIE

Nicotinamide Adenine Dinucleotide Phosphate Reduced Oxidase 5 (Nox5) Regulation by Angiotensin II and Endothelin-1 Is Mediated via Calcium/Calmodulin-Dependent, Rac-1-Independent Pathways in Human Endothelial Cells

(2010) Augusto C. Montezano et al.   CIRCULATION RESEARCH

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Inflammatory and Angiogenic Factors in the Aqueous Humor and the Relationship to Diabetic Retinopathy

(2010) In Kyung Oh et al.   CURRENT EYE RESEARCH

Candesartan Attenuates Diabetic Retinal Vascular Pathology by Restoring Glyoxalase-I Function

(2010) A. G. Miller et al.   DIABETES

Inhibition of Reactive Oxygen Species by Lovastatin Downregulates Vascular Endothelial Growth Factor Expression and Ameliorates Blood-Retinal Barrier Breakdown in db/db Mice: Role of NADPH Oxidase 4

(2010) J. Li et al.   DIABETES

Muller Cell-Derived VEGF Is Essential for Diabetes-Induced Retinal Inflammation and Vascular Leakage

(2010) J. Wang et al.   DIABETES

Müller glial dysfunction during diabetic retinopathy in rats is linked to accumulation of advanced glycation end-products and advanced lipoxidation end-products

(2010) T. M. Curtis et al.   DIABETOLOGIA

HIF-1α signaling is augmented during intermittent hypoxia by induction of the Nrf2 pathway in NOX1-expressing adenocarcinoma A549 cells

(2010) Viktor Malec et al.   FREE RADICAL BIOLOGY AND MEDICINE

Inactivation of Adenosine A2AReceptor Attenuates Basal and Angiotensin II-induced ROS Production by Nox2 in Endothelial Cells

(2010) Sapna Thakur et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neovascularization in an arterio-venous loop-containing tissue engineering chamber: role of NADPH oxidase

(2010) F. Jiang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Interleukin-1β induces angiogenesis and innervation in human intervertebral disc degeneration

(2010) Jae Man Lee et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

The NADPH Oxidase Subunit NOX4 Is a New Target Gene of the Hypoxia-inducible Factor-1

(2010) Isabel Diebold et al.   MOLECULAR BIOLOGY OF THE CELL

NADPH oxidase-4 mediates protection against chronic load-induced stress in mouse hearts by enhancing angiogenesis

(2010) M. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NADPH OxidaseversusMitochondria-Derived ROS in Glucose-Induced Apoptosis of Pericytes in Early Diabetic Retinopathy

(2010) Nik M. Mustapha et al.   Journal of Ophthalmology

Repeated intravitreal bevacizumab (Avastin®) treatment of persistent new vessels in proliferative diabetic retinopathy after complete panretinal photocoagulation

(2009) Gerald Schmidinger et al.   ACTA OPHTHALMOLOGICA

The Hypoxia-Inducible Factor-2α Is Stabilized by Oxidative Stress Involving NOX4

(2009) Isabel Diebold et al.   ANTIOXIDANTS & REDOX SIGNALING

Nox2-Containing NADPH Oxidase Deficiency Confers Protection From Hindlimb Ischemia in Conditions of Increased Oxidative Stress

(2009) Paola Haddad et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The role of advanced glycation end products in retinal ageing and disease

(2009) Josephine V. Glenn et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Expression and Distribution of NADPH Oxidase Isoforms in Human Myometrium—Role in Angiotensin II-induced Hypertrophy1

(2009) Xiao-Lan Cui et al.   BIOLOGY OF REPRODUCTION

Promise and potential pitfalls of anti-VEGF drugs in retinopathy of prematurity

(2009) B A Darlow et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

Phosphodiesterase 2 Mediates Redox-Sensitive Endothelial Cell Proliferation and Angiogenesis by Thrombin via Rac1 and NADPH Oxidase 2

(2009) Isabel Diebold et al.   CIRCULATION RESEARCH

Involvement of Angiotensin II-Dependent Vascular Endothelial Growth Factor Gene Expression via NADPH Oxidase in the Retina in a Type 2 Diabetic Rat Model

(2009) Masanori Fukumoto et al.   CURRENT EYE RESEARCH

Antivascular endothelial growth factor for retinopathy of prematurity

(2009) Helen A Mintz-Hittner et al.   CURRENT OPINION IN PEDIATRICS

The development of the rat model of retinopathy of prematurity

(2009) Joshua M. Barnett et al.   DOCUMENTA OPHTHALMOLOGICA

Inactivation of astroglial NF-κB promotes survival of retinal neurons following ischemic injury

(2009) Galina Dvoriantchikova et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Critical Role of Apoptosis Signal-Regulating Kinase 1 in Aldosterone/Salt-Induced Cardiac Inflammation and Fibrosis

(2009) Taishi Nakamura et al.   HYPERTENSION

Interleukin 10 inhibits interferon γ- and tumor necrosis factor α-stimulated activation of NADPH oxidase 1 in human colonic epithelial cells and the mouse colon

(2009) Mai Kamizato et al.   JOURNAL OF GASTROENTEROLOGY

Müller cell-derived VEGF is a significant contributor to retinal neovascularization

(2009) Yanyan Bai et al.   JOURNAL OF PATHOLOGY

Early Intervention of Tyrosine Nitration Prevents Vaso-Obliteration and Neovascularization in Ischemic Retinopathy

(2009) M. A. Abdelsaid et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

NADPH oxidase isoform selective regulation of endothelial cell proliferation and survival

(2009) Hitesh Peshavariya et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Neuronal and glial cell expression of angiotensin II type 1 (AT1) and type 2 (AT2) receptors in the rat retina

(2009) L.E. Downie et al.   NEUROSCIENCE

Renal and Retinal Effects of Enalapril and Losartan in Type 1 Diabetes

(2009) Michael Mauer et al.   NEW ENGLAND JOURNAL OF MEDICINE

Suppression of Retinal Neovascularization by Small-Interference RNA Targeting Erythropoietin

(2009) Si-Qi Xiong et al.   OPHTHALMOLOGICA

Simultaneous Analyses of Vitreous Levels of 27 Cytokines in Eyes with Retinopathy of Prematurity

(2009) Tatsuhiko Sato et al.   OPHTHALMOLOGY

Micronutrients and Diabetic Retinopathy

(2009) Chee-Tin Christine Lee et al.   OPHTHALMOLOGY

Oxygen-Induced Retinopathy in Mice: Amplification by Neonatal IGF-I Deficit and Attenuation by IGF-I Administration

(2009) Sophie Vanhaesebrouck et al.   PEDIATRIC RESEARCH

Role of Nox4 and Nox2 in Hyperoxia-Induced Reactive Oxygen Species Generation and Migration of Human Lung Endothelial Cells

(2008) Srikanth Pendyala et al.   ANTIOXIDANTS & REDOX SIGNALING

Inhibition of Retinopathy and Retinal Metabolic Abnormalities in Diabetic Rats With AREDS-Based Micronutrients

(2008) Renu A. Kowluru   ARCHIVES OF OPHTHALMOLOGY

TNF-α upregulates the A 2B adenosine receptor gene: The role of NAD(P)H oxidase 4

(2008) Cynthia St. Hilaire et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reactive oxygen species and HIF-1 signalling in cancer

(2008) Alex Galanis et al.   CANCER LETTERS

Role of Nox2-Based NADPH Oxidase in Bone Marrow and Progenitor Cell Function Involved in Neovascularization Induced by Hindlimb Ischemia

(2008) Norifumi Urao et al.   CIRCULATION RESEARCH

Identification of a Retinal Aldosterone System and the Protective Effects of Mineralocorticoid Receptor Antagonism on Retinal Vascular Pathology

(2008) Jennifer L. Wilkinson-Berka et al.   CIRCULATION RESEARCH

Tumor necrosis factor α activates transcription of the NADPH oxidase organizer 1 (NOXO1) gene and upregulates superoxide production in colon epithelial cells

(2008) Yuki Kuwano et al.   FREE RADICAL BIOLOGY AND MEDICINE

Distinct roles of Nox1 and Nox4 in basal and angiotensin II-stimulated superoxide and hydrogen peroxide production

(2008) S DIKALOV et al.   FREE RADICAL BIOLOGY AND MEDICINE

AT1 receptor inhibition prevents astrocyte degeneration and restores vascular growth in oxygen-induced retinopathy

(2008) Laura E. Downie et al.   GLIA

Renal Redox-Sensitive Signaling, but Not Blood Pressure, Is Attenuated by Nox1 Knockout in Angiotensin II–Dependent Chronic Hypertension

(2008) Alvaro Yogi et al.   HYPERTENSION

Clinical practices in neonatal oxygenation: where have we failed? What can we do?

(2008) A Sola et al.   Journal of Perinatology

Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials

(2008) Nish Chaturvedi et al.   LANCET

Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): a randomised placebo-controlled trial

(2008) Anne Katrin Sjølie et al.   LANCET

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

(2008) Zoltan Arany et al.   NATURE

NADPH oxidase 1 plays a critical mediating role in oncogenic Ras-induced vascular endothelial growth factor expression

(2008) D Komatsu et al.   ONCOGENE

Effect of Intravitreal Bevacizumab Injection on Aqueous Humor Cytokine Levels in Clinically Significant Macular Edema

(2008) Mi In Roh et al.   OPHTHALMOLOGY

NADPH oxidases in the vasculature: Molecular features, roles in disease and pharmacological inhibition

(2008) Stavros Selemidis et al.   PHARMACOLOGY & THERAPEUTICS

Prolyl hydroxylase inhibition during hyperoxia prevents oxygen-induced retinopathy

(2008) J. E. Sears et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunological mechanisms in the pathogenesis of diabetic retinopathy

(2008) Anthony P. Adamis et al.   Seminars in Immunopathology

Oxidative stress in vascular disease: causes, defense mechanisms and potential therapies

(2008) Ulrich Förstermann   Nature clinical practice. Cardiovascular medicine

Influence of rosuvastatin on the NAD(P)H oxidase activity in the retina and electroretinographic response of spontaneously hypertensive rats

(2007) P Sicard et al.   BRITISH JOURNAL OF PHARMACOLOGY

Vitreous Levels of Stromal Cell–Derived Factor 1 and Vascular Endothelial Growth Factor in Patients with Retinopathy of Prematurity

(2007) Kenan Sonmez et al.   OPHTHALMOLOGY