Nuclear Factor-κB: a Key Regulator in Health and Disease of Lungs

Morphine Induces Defects in Early Response of Alveolar Macrophages to Streptococcus pneumoniae by Modulating TLR9-NF- B Signaling

(2014) J. Wang et al.   JOURNAL OF IMMUNOLOGY

Inhibition of NF-κB Signaling Reduces Virus Load and Gammaherpesvirus-Induced Pulmonary Fibrosis

(2010) Laurie T. Krug et al.   AMERICAN JOURNAL OF PATHOLOGY

Inhibition of Urokinase Activity Reduces Primary Tumor Growth and Metastasis Formation in a Murine Lung Carcinoma Model

(2010) Ingrid Henneke et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

NF-κB targeting by way of IKK inhibition sensitizes lung cancer cells to adenovirus delivery of TRAIL

(2010) Cigdem Aydin et al.   BMC CANCER

Nuclear Factor-κB modulates cellular glutathione and prevents oxidative stress in cancer cells

(2010) Qinghang Meng et al.   CANCER LETTERS

Thiocolchicoside Exhibits Anticancer Effects through Downregulation of NF- B Pathway and Its Regulated Gene Products Linked to Inflammation and Cancer

(2010) S. Reuter et al.   Cancer Prevention Research

Effect of NF-κB Signaling on Apoptosis in Chronic Inflammation-Associated Carcinogenesis

(2010) H. Wang et al.   CURRENT CANCER DRUG TARGETS

Rhinovirus induces MUC5AC in a human infection model and in vitro via NF- B and EGFR pathways

(2010) C. A. Hewson et al.   EUROPEAN RESPIRATORY JOURNAL

Modification of Cysteine 179 of IκBα Kinase by Nimbolide Leads to Down-regulation of NF-κB-regulated Cell Survival and Proliferative Proteins and Sensitization of Tumor Cells to Chemotherapeutic Agents

(2010) Subash C. Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXCL1 Regulates Pulmonary Host Defense to Klebsiella Infection via CXCL2, CXCL5, NF- B, and MAPKs

(2010) S. Cai et al.   JOURNAL OF IMMUNOLOGY

Bortezomib Plus Gemcitabine/Carboplatin as First-Line Treatment of Advanced Non-small Cell Lung Cancer: A Phase II Southwest Oncology Group Study (S0339)

(2010) Angela M. Davies et al.   Journal of Thoracic Oncology

Benzyl Isothiocyanate-Mediated Inhibition of Histone Deacetylase Leads to NF- B Turnoff in Human Pancreatic Carcinoma Cells

(2010) S. Batra et al.   MOLECULAR CANCER THERAPEUTICS

STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

(2010) Dimitrios Iliopoulos et al.   MOLECULAR CELL

Mechanisms of Neutrophil Accumulation in the Lungs Against Bacteria

(2009) Gayathriy Balamayooran et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Molecular mechanisms involved in farnesol-induced apoptosis

(2009) Joung Hyuck Joo et al.   CANCER LETTERS

Negative regulation of NF-κB action by Set9-mediated lysine methylation of the RelA subunit

(2009) Xiao-Dong Yang et al.   EMBO JOURNAL

Cigarette Smoke Exposure Impairs Pulmonary Bacterial Clearance and Alveolar Macrophage Complement-Mediated Phagocytosis of Streptococcus pneumoniae

(2009) J. C. Phipps et al.   INFECTION AND IMMUNITY

Randomized Phase II Trial of Docetaxel Plus Cetuximab or Docetaxel Plus Bortezomib in Patients With Advanced Non–Small-Cell Lung Cancer and a Performance Status of 2: CALGB 30402

(2009) Rogerio Lilenbaum et al.   JOURNAL OF CLINICAL ONCOLOGY

Both TRIF- and MyD88-Dependent Signaling Contribute to Host Defense against Pulmonary Klebsiella Infection

(2009) S. Cai et al.   JOURNAL OF IMMUNOLOGY

Phase I trial of carboplatin/paclitaxel/bortezomib and concurrent radiotherapy followed by surgical resection in Stage III non-small cell lung cancer

(2009) Martin J. Edelman et al.   LUNG CANCER

A randomized phase II study of bortezomib and pemetrexed, in combination or alone, in patients with previously treated advanced non-small-cell lung cancer

(2009) Giorgio V. Scagliotti et al.   LUNG CANCER

Requirement for NF-κB signalling in a mouse model of lung adenocarcinoma

(2009) Etienne Meylan et al.   NATURE

Regulation of NF-κB activity through lysine monomethylation of p65

(2009) Chee-Kwee Ea et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of NF- B by NSD1/FBXL11-dependent reversible lysine methylation of p65

(2009) T. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic Ablation of NADPH Oxidase Enhances Susceptibility to Cigarette Smoke-Induced Lung Inflammation and Emphysema in Mice

(2008) Hongwei Yao et al.   AMERICAN JOURNAL OF PATHOLOGY

PPARβ/δ agonist stimulates human lung carcinoma cell growth through inhibition of PTEN expression: the involvement of PI3K and NF-κB signals

(2008) ShouWei Han et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Myeloid Differentiation Protein-2–Dependent and –Independent Neutrophil Accumulation duringEscherichia coliPneumonia

(2008) Shanshan Cai et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Streptococcus pneumoniae synergizes with nontypeable Haemophilus influenzae to induce inflammation via upregulating TLR2

(2008) Jae Lim et al.   BMC IMMUNOLOGY

Inflammation in the development of lung cancer: epidemiological evidence

(2008) Eric A Engels   Expert Review of Anticancer Therapy

Genetic deficiency of NADPH oxidase does not diminish, but rather enhances, LPS-induced acute inflammatory responses in vivo

(2008) Wei-Jian Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cigarette smoking and innate immunity

(2008) H. Mehta et al.   INFLAMMATION RESEARCH

Blockage of NF-κB by IKKβ- or RelA-siRNA rather than the NF-κB super-suppressor IκBα mutant potentiates adriamycin-induced cytotoxicity in lung cancer cells

(2008) Wenshu Chen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Proteasome Inhibitor Bortezomib in Combination with Gemcitabine and Carboplatin in Advanced Non-small Cell Lung Cancer: A California Cancer Consortium Phase I Study

(2008) Angela M. Davies et al.   Journal of Thoracic Oncology

Acute Lower Respiratory Tract Infection

(2008) Joseph P. Mizgerd   NEW ENGLAND JOURNAL OF MEDICINE