Neuritogenic Militarinone-Inspired 4-Hydroxypyridones Target the Stress Pathway Kinase MAP4K4
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Title
Neuritogenic Militarinone-Inspired 4-Hydroxypyridones Target the Stress Pathway Kinase MAP4K4
Authors
Keywords
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Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 54, Issue 42, Pages 12398-12403
Publisher
Wiley
Online
2015-04-23
DOI
10.1002/anie.201501515
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Note: Only part of the references are listed.- Fragment-based identification and optimization of a class of potent pyrrolo[2,1- f ][1,2,4]triazine MAP4K4 inhibitors
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- Combined inhibition of Cdk5 and ROCK additively increase cell survival, but not the regenerative response in regenerating retinal ganglion cells
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