JNK: A Stress-Activated Protein Kinase Therapeutic Strategies and Involvement in Alzheimer’s and Various Neurodegenerative Abnormalities

Amelioration of intracerebroventricular streptozotocin induced cognitive dysfunction and oxidative stress by vinpocetine — a PDE1 inhibitor

(2009) Rahul Deshmukh et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Activation of c-Jun-N-terminal kinase and decline of mitochondrial pyruvate dehydrogenase activity during brain aging

(2009) Qiongqiong Zhou et al.   FEBS LETTERS

Specific activities of individual c-Jun N-terminal kinases in the brain

(2009) W. Haeusgen et al.   NEUROSCIENCE

JNK1 regulates histone acetylation in trigeminal neurons following chemical stimulation

(2008) Jing Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Insulin resistance and amyloidogenesis as common molecular foundation for type 2 diabetes and Alzheimer's disease

(2008) Wei-Qin Zhao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The JIP1 Scaffold Protein Regulates Axonal Development in Cortical Neurons

(2008) Federico Dajas-Bailador et al.   CURRENT BIOLOGY

c-Jun N-terminal kinase 1 is deleterious to the function and survival of murine pancreatic islets

(2008) J. L. Varona-Santos et al.   DIABETOLOGIA

Rapid and bi-directional regulation of AMPA receptor phosphorylation and trafficking by JNK

(2008) Gareth M Thomas et al.   EMBO JOURNAL

Toll-like receptor-4 mediates neuronal apoptosis induced by amyloid β-peptide and the membrane lipid peroxidation product 4-hydroxynonenal

(2008) Sung-Chun Tang et al.   EXPERIMENTAL NEUROLOGY

Low-density lipoprotein receptors regulate microglial inflammation through c-Jun N-terminal kinase

(2008) Ana Pocivavsek et al.   GLIA

The β-Arrestin-2 Scaffold Protein Promotes c-Jun N-terminal Kinase-3 Activation by Binding to Its Nonconserved N Terminus

(2008) Chun Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hydrogen Peroxide Promotes Aβ Production through JNK-dependent Activation of γ-Secretase

(2008) Chengyong Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Crystal Structure of JNK2 Reveals Conformational Flexibility in the MAP Kinase Insert and Indicates Its Involvement in the Regulation of Catalytic Activity

(2008) David Shaw et al.   JOURNAL OF MOLECULAR BIOLOGY

c-Jun N-terminal kinases trigger both degeneration and neurite outgrowth in primary hippocampal and cortical neurons

(2008) S. Eminel et al.   JOURNAL OF NEUROCHEMISTRY

Neuron-microglia crosstalk up-regulates neuronal FGF-2 expression which mediates neuroprotection against excitotoxicity via JNK1/2

(2008) Catarina Figueiredo et al.   JOURNAL OF NEUROCHEMISTRY

The scaffold protein JSAP1 regulates proliferation and differentiation of cerebellar granule cell precursors by modulating JNK signaling

(2008) Tokiharu Sato et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

D-JNKi, a peptide inhibitor of c-Jun N-terminal kinase, promotes functional recovery after transient focal cerebral ischemia in rats

(2008) E. Esneault et al.   NEUROSCIENCE

c-Jun N-terminal kinase binding domain–dependent phosphorylation of mitogen-activated protein kinase kinase 4 and mitogen-activated protein kinase kinase 7 and balancing cross-talk between c-Jun N-terminal kinase and extracellular signal-regulated kinase pathways in cortical neurons

(2008) M. Repici et al.   NEUROSCIENCE

Luteolin reduces IL-6 production in microglia by inhibiting JNK phosphorylation and activation of AP-1

(2008) S. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AS601245, a c-Jun NH2-terminal kinase (JNK) inhibitor, reduces axon/dendrite damage and cognitive deficits after global cerebral ischaemia in gerbils

(2007) S Carboni et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activating transcription factor 3 up-regulated by c-Jun NH2-terminal kinase/c-Jun contributes to apoptosis induced by potassium deprivation in cerebellar granule neurons

(2007) Y. Mei et al.   NEUROSCIENCE