Conformational Selection in Glycomimetics: Human Galectin-1 Only Recognizessyn-Ψ-Type Conformations of β-1,3-Linked Lactose and ItsC-Glycosyl Derivative

Context-dependent multifunctionality of galectin-1: a challenge for defining the lectin as therapeutic target

(2013) Karel Smetana et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The Third Dimension of Reading the Sugar Code by Lectins: Design of Glycoclusters with Cyclic Scaffolds as Tools with the Aim to Define Correlations between Spatial Presentation and Activity

(2013) Paul Murphy et al.   MOLECULES

Carbohydrate–Aromatic Interactions

(2012) Juan Luis Asensio et al.   ACCOUNTS OF CHEMICAL RESEARCH

Tumour suppressor p16INK4a- anoikis-favouring decrease in N/O-glycan/cell surface sialylation by down-regulation of enzymes in sialic acid biosynthesis in tandem in a pancreatic carcinoma model

(2012) Maho Amano et al.   FEBS Journal

Bi- to tetravalent glycoclusters: synthesis, structure–activity profiles as lectin inhibitors and impact of combining both valency and headgroup tailoring on selectivity

(2012) Guan-Nan Wang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Sensing ligand binding to a clinically relevant lectin by tryptophan fluorescence anisotropy

(2011) Antonia Göhler et al.   ANALYST

The Galβ-(syn)-gauche configuration is required for galectin-recognition disaccharides

(2011) Jun Iwaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Inhibitory potential of chemical substitutions at bioinspired sites of β-d-galactopyranose on neoglycoprotein/cell surface binding of two classes of medically relevant lectins

(2011) Denis Giguère et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Carbohydrate-Protein Interactions: A 3D View by NMR

(2011) Virginia Roldós et al.   CHEMBIOCHEM

Combining carbohydrate substitutions at bioinspired positions with multivalent presentation towards optimising lectin inhibitors: case study with calixarenes

(2011) Sabine André et al.   CHEMICAL COMMUNICATIONS

Structural aspects of binding of α-linked digalactosides to human galectin-1

(2011) Michelle C Miller et al.   GLYCOBIOLOGY

Galectins as tools for glycan mapping in histology: comparison of their binding profiles to the bovine zona pellucida by confocal laser scanning microscopy

(2011) Felix A. Habermann et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Quantitative immunohistochemical fingerprinting of adhesion/growth-regulatory galectins in salivary gland tumours: divergent profiles with diagnostic potential

(2011) Myriam Remmelink et al.   HISTOPATHOLOGY

Cyclic neoglycodecapeptides: how to increase their inhibitory activity and selectivity on lectin/toxin binding to a glycoprotein and cells

(2011) Sabine André et al.   JOURNAL OF PEPTIDE SCIENCE

Symmetric dithiodigalactoside: strategic combination of binding studies and detection of selectivity between a plant toxin and human lectins

(2011) Sonsoles Martín-Santamaría et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Structural studies on the interaction of saccharides and glycomimetics with galectin-1: A 3D perspective using a combined molecular modeling and NMR approach

(2011) Sonsoles Martín-Santamaría et al.   PURE AND APPLIED CHEMISTRY

From lectin structure to functional glycomics: principles of the sugar code

(2011) Hans-Joachim Gabius et al.   TRENDS IN BIOCHEMICAL SCIENCES

Galectin-1 sensitizes carcinoma cells to anoikis via the fibronectin receptor α5β1-integrin

(2010) H Sanchez-Ruderisch et al.   CELL DEATH AND DIFFERENTIATION

Tumor suppressor p16INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model

(2010) Hugo Sanchez-Ruderisch et al.   FEBS Journal

How adhesion/growth-regulatory galectins-1 and -3 attain cell specificity: Case study defining their target on neuroblastoma cells (SK-N-MC) and marked affinity regulation by affecting microdomain organization of the membrane

(2010) Jürgen Kopitz et al.   IUBMB LIFE

Synthesis and screening of a small glycomimetic library for inhibitory activity on medically relevant galactoside-specific lectins in assays of increasing biorelevance

(2010) Sabine André et al.   NEW JOURNAL OF CHEMISTRY

Aromatic-Carbohydrate Interactions: An NMR and Computational Study of Model Systems

(2008) Sophie Vandenbussche et al.   CHEMISTRY-A EUROPEAN JOURNAL

Galectin-1 Is a Novel Functional Receptor for Tissue Plasminogen Activator in Pancreatic Cancer

(2008) Oriol Roda et al.   GASTROENTEROLOGY