Symmetric dithiodigalactoside: strategic combination of binding studies and detection of selectivity between a plant toxin and human lectins

Cyclic neoglycodecapeptides: how to increase their inhibitory activity and selectivity on lectin/toxin binding to a glycoprotein and cells

(2011) Sabine André et al.   JOURNAL OF PEPTIDE SCIENCE

Human galectin-3 (Mac-2 antigen): Defining molecular switches of affinity to natural glycoproteins, structural and dynamic aspects of glycan binding by flexible ligand docking and putative regulatory sequences in the proximal promoter region

(2010) Mickaël Krzeminski et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Galectin inhibitory disaccharides promote tumour immunity in a breast cancer model

(2010) Kimberley A. Stannard et al.   CANCER LETTERS

Phosphine-mediated disulfide metathesis in aqueous media

(2010) Rémi Caraballo et al.   CHEMICAL COMMUNICATIONS

Lectin-Based Drug Design: Combined Strategy to Identify Lead Compounds using STD NMR Spectroscopy, Solid-Phase Assays and Cell Binding for a Plant Toxin Model

(2010) João P. Ribeiro et al.   ChemMedChem

Towards sugar derivatives as toxin-blocking pharmaceuticals: STD NMR spectroscopy as versatile tool for affinity assessment in drug development

(2010) João P. Ribeiro et al.   COMPTES RENDUS CHIMIE

Tumor suppressor p16INK4a: Downregulation of galectin-3, an endogenous competitor of the pro-anoikis effector galectin-1, in a pancreatic carcinoma model

(2010) Hugo Sanchez-Ruderisch et al.   FEBS Journal

N-domain of human adhesion/growth-regulatory galectin-9: Preference for distinct conformers and non-sialylated N-glycans and detection of ligand-induced structural changes in crystal and solution

(2010) Dolores Solís et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Selenoglycosides in silico: ab initio-derived reparameterization of MM4, conformational analysis using histo-blood group ABH antigens and lectin docking as indication for potential of bioactivity

(2010) Francesco Strino et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Synthesis and screening of a small glycomimetic library for inhibitory activity on medically relevant galactoside-specific lectins in assays of increasing biorelevance

(2010) Sabine André et al.   NEW JOURNAL OF CHEMISTRY

Binding studies of adhesion/growth-regulatory galectins with glycoconjugates monitored by surface plasmon resonance and NMR spectroscopy

(2010) F. Javier Muñoz et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and Conformational Analysis of (α-D-Galactosyl)phenylmethane and α-,β-Difluoromethane Analogues: Interactions with the Plant Lectin Viscumin

(2009) Maria Kolympadi et al.   CHEMISTRY-A EUROPEAN JOURNAL

α-O-Linked Glycopeptide Mimetics: Synthesis, Conformation Analysis, and Interactions with Viscumin, a Galactoside-Binding Model Lectin

(2009) Jesús Jiménez-Barbero et al.   CHEMISTRY-A EUROPEAN JOURNAL

Conformational analysis of thioglycoside derivatives of histo-blood group ABH antigens using an ab initio-derived reparameterization of MM4: implications for design of non-hydrolysable mimetics

(2009) Francesco Strino et al.   JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN

Synthesis of Bivalent Lactosides Based on Terephthalamide,N,N′-Diglucosylterephthalamide, and Glycophane Scaffolds and Assessment of Their Inhibitory Capacity on Medically Relevant Lectins

(2009) Rosaria Leyden et al.   JOURNAL OF ORGANIC CHEMISTRY

Phosphorylated human galectin-3: Facile large-scale preparation of active lectin and detection of structural changes by CD spectroscopy

(2008) Dieter Kübler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Synthesis of anomeric sulfonamides and their behaviour under radical-mediated bromination conditions

(2008) Katalin Czifrák et al.   CARBOHYDRATE RESEARCH

Human galectins as sensors for apoptosis/necrosis-associated surface changes of granulocytes and lymphocytes

(2008) Alexandra Beer et al.   CYTOMETRY PART A

Domain versatility in plant AB-toxins: Evidence for a local, pH-dependent rearrangement in the 2γ lectin site of the mistletoe lectin by applying ligand derivatives and modelling

(2008) Marta Jiménez et al.   FEBS LETTERS

Galectin-1 Is a Novel Functional Receptor for Tissue Plasminogen Activator in Pancreatic Cancer

(2008) Oriol Roda et al.   GASTROENTEROLOGY