Domain structure and function of matrix metalloprotease 23 (MMP23): role in potassium channel trafficking

Perforin: structure, function, and role in human immunopathology

(2015) Ilia Voskoboinik et al.   IMMUNOLOGICAL REVIEWS

Protease-activated Receptor 2 (PAR2) Protein and Transient Receptor Potential Vanilloid 4 (TRPV4) Protein Coupling Is Required for Sustained Inflammatory Signaling

(2013) Daniel P. Poole et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intracellular Trafficking of the KV1.3 Potassium Channel Is Regulated by the Prodomain of a Matrix Metalloprotease

(2013) Hai M. Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Crystal Structure of Human α2-Macroglobulin Reveals a Unique Molecular Cage

(2012) Aniebrys Marrero et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inhibiting Matrix Metalloproteinases, an Old Story with New Potentials for Cancer Treatment

(2012) Dimitris Stellas et al.   Anti-Cancer Agents in Medicinal Chemistry

Matrix metalloproteases and PAR1 activation

(2012) K. M. Austin et al.   BLOOD

Differential Expression of Kv1.3 and Kv1.5 Voltage-Dependent K+Channels in Human Skeletal Muscle Sarcomas

(2012) Joanna Bielanska et al.   CANCER INVESTIGATION

Proteomic Identification of Matrix Metalloproteinase Substrates in the Human Vasculature

(2012) Christin Stegemann et al.   Circulation-Cardiovascular Genetics

Targeting the Voltage-Dependent K+ Channels Kv1.3 and Kv1.5 as Tumor Biomarkers for Cancer Detection and Prevention

(2012) A. Felipe et al.   CURRENT MEDICINAL CHEMISTRY

Inflammatory Mechanisms in Atherosclerosis: The Impact of Matrix Metalloproteinases

(2012) Gerasimos Siasos et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Molecular Mechanisms Regulating Matrix Metalloproteinases

(2012) Christina Piperi et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells

(2012) Luigi Leanza et al.   EMBO Molecular Medicine

Trafficking mechanisms underlying neuronal voltage-gated ion channel localization at the axon initial segment

(2012) Helene Vacher et al.   EPILEPSIA

Site-specific cellular functions of MT1-MMP

(2012) Agnieszka Koziol et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

A C-terminally amidated analogue of ShK is a potent and selective blocker of the voltage-gated potassium channel Kv1.3

(2012) Michael W. Pennington et al.   FEBS LETTERS

SH3 domain ligand binding: What's the consensus and where's the specificity?

(2012) Kalle Saksela et al.   FEBS LETTERS

Cdon and Boc: Two transmembrane proteins implicated in cell–cell communication

(2012) Luisa Sanchez-Arrones et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Molecular Characterization of Porcine MMP19 and MMP23B Genes and Its Association with Immune Traits

(2012) Shuanping Zhao et al.   International Journal of Biological Sciences

What Hydra can teach us about chemical ecology how a simple, soft organism survives in a hostile aqueous environment

(2012) Tamar Rachamim et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Plasmin and chymotrypsin have distinct preferences for channel activating cleavage sites in the γ subunit of the human epithelial sodium channel

(2012) Silke Haerteis et al.   JOURNAL OF GENERAL PHYSIOLOGY

Facile backbone structure determination of human membrane proteins by NMR spectroscopy

(2012) Christian Klammt et al.   NATURE METHODS

Proteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-S

(2012) Silke Haerteis et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Modulation of voltage-gated K+ channels by the sodium channel  1 subunit

(2012) H. M. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nuclear localization of Matrix metalloproteinases

(2012) Ferdinando Mannello et al.   PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY

The Amyloid Precursor Protein Has a Flexible Transmembrane Domain and Binds Cholesterol

(2012) P. J. Barrett et al.   SCIENCE

Protecting a serial killer: pathways for perforin trafficking and self-defence ensure sequential target cell death

(2012) Jamie A. Lopez et al.   TRENDS IN IMMUNOLOGY

KCNE Regulation of K+ Channel Trafficking – a Sisyphean Task?

(2012) Vikram A. Kanda et al.   Frontiers in Physiology

Vascular remodelling in human skeletal muscle

(2011) Thomas Gustafsson   BIOCHEMICAL SOCIETY TRANSACTIONS

KCNE1 and KCNE2 Provide a Checkpoint Governing Voltage-Gated Potassium Channel α-Subunit Composition

(2011) Vikram A. Kanda et al.   BIOPHYSICAL JOURNAL

Matrix metalloproteinases in tumorigenesis: an evolving paradigm

(2011) Hui Hua et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Proteolytic activation of the epithelial sodium channel and therapeutic application of a serine protease inhibitor for the treatment of salt-sensitive hypertension

(2011) Kenichiro Kitamura et al.   Clinical and Experimental Nephrology

Roles of Metalloproteases in Metastatic Niche

(2011) N. Rucci et al.   CURRENT MOLECULAR MEDICINE

Working model for the structural basis for KCNE1 modulation of the KCNQ1 potassium channel

(2011) Wade D Van Horn et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Matrix metalloproteinases: protective roles in cancer

(2011) Julie Decock et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Human matrix metalloproteinases: An ubiquitarian class of enzymes involved in several pathological processes

(2011) Diego Sbardella et al.   MOLECULAR ASPECTS OF MEDICINE

LIM kinase1 modulates function of membrane type matrix metalloproteinase 1: implication in invasion of prostate cancer cells

(2011) Tenekua Tapia et al.   Molecular Cancer

Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases

(2011) Victor Chi et al.   TOXICON

Tissue inhibitors of metalloproteinases

(2011) Gillian Murphy   GENOME BIOLOGY

Physiology and pathophysiology of matrix metalloproteases

(2010) T. Klein et al.   AMINO ACIDS

The tissue inhibitors of metalloproteinases (TIMPs): An ancient family with structural and functional diversity

(2010) Keith Brew et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Matrix Metalloproteinases

(2010) O. Zitka et al.   CURRENT MEDICINAL CHEMISTRY

MT1-MMP Is Required for Myeloid Cell Fusion via Regulation of Rac1 Signaling

(2010) Pilar Gonzalo et al.   DEVELOPMENTAL CELL

Regulation of matrix metalloproteinase activity in health and disease

(2010) Elin Hadler-Olsen et al.   FEBS Journal

Golgi reassembly stacking protein 55 interacts with membrane-type (MT) 1-matrix metalloprotease (MMP) and furin and plays a role in the activation of the MT1-MMP zymogen

(2010) Christian Roghi et al.   FEBS Journal

Localizing matrix metalloproteinase activities in the pericellular environment

(2010) Gillian Murphy et al.   FEBS Journal

Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting

(2010) Chrisostomi Gialeli et al.   FEBS Journal

K+ channels as therapeutic targets in oncology

(2010) Walter Stühmer et al.   Future Medicinal Chemistry

Mmp23b promotes liver development and hepatocyte proliferation through the tumor necrosis factor pathway in zebrafish

(2010) Fei Qi et al.   HEPATOLOGY

Abl Kinases Are Required for Invadopodia Formation and Chemokine-induced Invasion

(2010) Pameeka S. Smith-Pearson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proenzyme Structure and Activation of Astacin Metallopeptidase

(2010) Tibisay Guevara et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Membrane Protease Regulates Energy Production in Macrophages by Activating Hypoxia-inducible Factor-1 via a Non-proteolytic Mechanism

(2010) Takeharu Sakamoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structural basis for membrane binding and pore formation by lymphocyte perforin

(2010) Ruby H. P. Law et al.   NATURE

Electrophysiology and beyond: Multiple roles of Na+ channel β subunits in development and disease

(2010) Gustavo A. Patino et al.   NEUROSCIENCE LETTERS

The metzincins - Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc-peptidases

(2010) Walter Stöcker et al.   PROTEIN SCIENCE

Matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs): Positive and negative regulators in tumor cell adhesion

(2010) Dimitra Bourboulia et al.   SEMINARS IN CANCER BIOLOGY

Molecular Mechanisms of TRPV4-Mediated Neural Signaling

(2009) Wolfgang Liedtke   Annals of the New York Academy of Sciences

Updated Biological Roles for Matrix Metalloproteinases and New “Intracellular” Substrates Revealed by Degradomics

(2009) Georgina S. Butler et al.   BIOCHEMISTRY

Matrix metalloproteinases: Fold and function of their catalytic domains

(2009) Cynthia Tallant et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Matrix metalloproteinases: Evolution, gene regulation and functional analysis in mouse models

(2009) Miriam Fanjul-Fernández et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Matrix metalloproteinases: What do they not do? New substrates and biological roles identified by murine models and proteomics

(2009) David Rodríguez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Voltage-Dependent Potassium Channels Kv1.3 and Kv1.5 in Human Cancer

(2009) J. Bielanska et al.   CURRENT CANCER DRUG TARGETS

Targeting Matrix Metalloproteinases in Inflammatory Conditions

(2009) A. Clutterbuck et al.   CURRENT DRUG TARGETS

Matrix metalloproteinase proteomics: substrates, targets, and therapy

(2009) Charlotte J Morrison et al.   CURRENT OPINION IN CELL BIOLOGY

Multiple Roles of the Extracellular Matrix in Inflammation

(2009) E. Korpos et al.   CURRENT PHARMACEUTICAL DESIGN

NUCLEAR LOCALIZATION OF ACTIVE MATRIX METALLOPROTEINASE-2 IN CIGARETTE SMOKE-EXPOSED APOPTOTIC ENDOTHELIAL CELLS

(2009) Aldonyte Ruta et al.   EXPERIMENTAL LUNG RESEARCH

Potassium Channel Modulation by a Toxin Domain in Matrix Metalloprotease 23

(2009) Srikant Rangaraju et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

KCNE4 suppresses Kv1.3 currents by modulating trafficking, surface expression and channel gating

(2009) L. Sole et al.   JOURNAL OF CELL SCIENCE

Increased intranuclear matrix metalloproteinase activity in neurons interferes with oxidative DNA repair in focal cerebral ischemia

(2009) Yi Yang et al.   JOURNAL OF NEUROCHEMISTRY

Structures of sea anemone toxins

(2009) Raymond S. Norton   TOXICON

Structural insight into Slit–Robo signalling

(2008) Erhard Hohenester   BIOCHEMICAL SOCIETY TRANSACTIONS

Identification of an Evolutionarily Conserved Extracellular Threonine Residue Critical for Surface Expression and Its Potential Coupling of Adjacent Voltage-sensing and Gating Domains in Voltage-gated Potassium Channels

(2008) Lynn Mckeown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Additional MDA-MB-231 breast cancer cell matrix metalloproteinases promote invasiveness

(2008) Luca Hegedüs et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Crystal Structure of the Ig1 Domain of the Neural Cell Adhesion Molecule NCAM2 Displays Domain Swapping

(2008) Kim K. Rasmussen et al.   JOURNAL OF MOLECULAR BIOLOGY

Gene expression profile analysis of primary glioblastomas and non-neoplastic brain tissue: identification of potential target genes by oligonucleotide microarray and real-time quantitative PCR

(2008) Carlos A. Scrideli et al.   JOURNAL OF NEURO-ONCOLOGY

Postsynaptic Density-93 Clusters Kv1 Channels at Axon Initial Segments Independently of Caspr2

(2008) Y. Ogawa et al.   JOURNAL OF NEUROSCIENCE

Novel Transcription Factor-Like Function of Human Matrix Metalloproteinase 3 Regulating the CTGF/CCN2 Gene

(2008) T. Eguchi et al.   MOLECULAR AND CELLULAR BIOLOGY

Tendinopathy—from basic science to treatment

(2008) Graham Riley   Nature clinical practice. Rheumatology

Metalloproteinases and their inhibitors: Regulators of wound healing

(2007) S GILL et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

RETRACTED: Activation and silencing of matrix metalloproteinases

(2007) X FU et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY