K+ channels as therapeutic targets in oncology

Kv1.3 voltage-gated K+ channel subunit as a potential diagnostic marker and therapeutic target for breast cancer

(2011) Soo-Hwa Jang et al.   BMB Reports

Expression and significance of HERG protein in gastric cancer

(2010) Xiao-Dong Shao et al.   CANCER BIOLOGY & THERAPY

Modulation of KCa channels increases anticancer drug delivery to brain tumors and prolongs survival in xenograft model

(2010) Nagendra S. Ningaraj et al.   CANCER BIOLOGY & THERAPY

The potassium channel Ether a go-go is a novel prognostic factor with functional relevance in acute myeloid leukemia

(2010) Jasmin R Agarwal et al.   Molecular Cancer

State-dependent block of HERG potassium channels by R-roscovitine: implications for cancer therapy

(2009) Sindura B. Ganapathi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Histamine hyperpolarizes human glioblastoma cells by activating the intermediate-conductance Ca2+-activated K+ channel

(2009) Bernard Fioretti et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Role of KCNMA1gene in breast cancer invasion and metastasis to brain

(2009) Divya Khaitan et al.   BMC CANCER

Estrogens and Human Papilloma Virus Oncogenes Regulate Human Ether-a-go-go-1 Potassium Channel Expression

(2009) L. Diaz et al.   CANCER RESEARCH

ATP-sensitive potassium channels control glioma cells proliferation by regulating ERK activity

(2009) Lianyan Huang et al.   CARCINOGENESIS

Intermediate conductance Ca2+-activated potassium channel (KCa3.1) in the inner mitochondrial membrane of human colon cancer cells

(2009) Umberto De Marchi et al.   CELL CALCIUM

DNA Methylation of Kv1.3 Potassium Channel Gene Promoter is Associated with Poorly Differentiated Breast Adenocarcinoma

(2009) Marie Brevet et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Expression and significance of HERG (KCNH2) potassium channels in the regulation of MDA-MB-435S melanoma cell proliferation and migration

(2009) Emad Afrasiabi et al.   CELLULAR SIGNALLING

Voltage-Dependent Potassium Channels Kv1.3 and Kv1.5 in Human Cancer

(2009) J. Bielanska et al.   CURRENT CANCER DRUG TARGETS

Prognostic Significance of hERG1 Expression in Gastric Cancer

(2009) Xiang-Wu Ding et al.   DIGESTIVE DISEASES AND SCIENCES

Calcitriol inhibits Ether-à go-go potassium channel expression and cell proliferation in human breast cancer cells

(2009) Rocío García-Becerra et al.   EXPERIMENTAL CELL RESEARCH

Voltage-gated potassium channels as therapeutic targets

(2009) Heike Wulff et al.   NATURE REVIEWS DRUG DISCOVERY

Intermediate-conductance Ca2+-activated K+ channels (IKCa1) regulate human prostate cancer cell proliferation through a close control of calcium entry

(2009) H Lallet-Daher et al.   ONCOGENE

Deregulation of 2 Potassium Channels in Pancreas Adenocarcinomas

(2009) Marie Brevet et al.   PANCREAS

hERG1 channel activators: A new anti-arrhythmic principle

(2009) Morten Grunnet et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Different effects of K Ca and K ATP agonists on brain tumor permeability between syngeneic and allogeneic rat models

(2008) Keith L. Black et al.   BRAIN RESEARCH

DNA Methylation in Tumor and Matched Normal Tissues from Non-Small Cell Lung Cancer Patients

(2008) Q. Feng et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

TREK-1 Is a Novel Molecular Target in Prostate Cancer

(2008) I. Voloshyna et al.   CANCER RESEARCH

Increase in Brain Tumor Permeability in Glioma-Bearing Rats with Nitric Oxide Donors

(2008) D. Yin et al.   CLINICAL CANCER RESEARCH

Activation of KATP channels increases anticancer drug delivery to brain tumors and survival

(2008) Nagendra S. Ningaraj et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

An Unexpected Role for Ion Channels in Brain Tumor Metastasis

(2008) Harald Sontheimer   EXPERIMENTAL BIOLOGY AND MEDICINE

Differential expression of potassium ion channels in human renal cell carcinoma

(2008) Surbhi Wadhwa et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Eag1 and Bestrophin 1 Are Up-regulated in Fast-growing Colonic Cancer Cells

(2008) Melanie Spitzner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Eag1 Expression Interferes with Hypoxia Homeostasis and Induces Angiogenesis in Tumors

(2008) Bryan R. Downie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The two-pore domain potassium channel TASK3 functionally impacts glioma cell death

(2008) Sven G. Meuth et al.   JOURNAL OF NEURO-ONCOLOGY

Identification of a Posttranslational Mechanism for the Regulation of hERG1 K+ Channel Expression and hERG1 Current Density in Tumor Cells

(2008) L. Guasti et al.   MOLECULAR AND CELLULAR BIOLOGY

Eag1 potassium channel immunohistochemistry in the CNS of adult rat and selected regions of human brain

(2008) S. Martin et al.   NEUROSCIENCE

Upregulation of colonic ion channels in APC Min/+ mice

(2008) Jiraporn Ousingsawat et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Activation of cell migration with fibroblast growth factor-2 requires calcium-sensitive potassium channels

(2008) Wolfram Kessler et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The hERG potassium channel and hERG screening for drug-induced torsades de pointes

(2008) Jules C. Hancox et al.   PHARMACOLOGY & THERAPEUTICS

Human ether-a-go-go related gene (hERG) K+ channels: Function and dysfunction

(2008) Mark J. Perrin et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Silencing of herg gene by shRNA inhibits SH-SY5Y cell growth in vitro and in vivo

(2007) Jie Zhao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY