Trafficking mechanisms underlying neuronal voltage-gated ion channel localization at the axon initial segment

A Pore Residue of the KCNQ3 Potassium M-Channel Subunit Controls Surface Expression

(2013) J. C. Gomez-Posada et al.   JOURNAL OF NEUROSCIENCE

The Physiology of the Axon Initial Segment

(2012) Kevin J. Bender et al.   Annual Review of Neuroscience

The mechanism of action of retigabine (ezogabine), a first-in-class K+ channel opener for the treatment of epilepsy

(2012) Martin J. Gunthorpe et al.   EPILEPSIA

Signal Processing in the Axon Initial Segment

(2012) Maarten H.P. Kole et al.   NEURON

Kv7.1 surface expression is regulated by epithelial cell polarization

(2011) Martin N. Andersen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Protein Folding and Modification in the Mammalian Endoplasmic Reticulum

(2011) Ineke Braakman et al.   Annual Review of Biochemistry

Characterization of the axon initial segment (AIS) of motor neurons and identification of a para-AIS and a juxtapara-AIS, organized by protein 4.1B

(2011) Amandine Duflocq et al.   BMC BIOLOGY

Differential subcellular distribution of ion channels and the diversity of neuronal function

(2011) Zoltan Nusser   CURRENT OPINION IN NEUROBIOLOGY

Pure haploinsufficiency for Dravet syndrome NaV1.1 (SCN1A) sodium channel truncating mutations

(2011) Giulia Bechi et al.   EPILEPSIA

Temperature and pharmacological rescue of a folding-defective, dominantl-negative KV7.2 mutation associated with neonatal seizures

(2011) Snezana Maljevic et al.   HUMAN MUTATION

Clustering and Activity Tuning of Kv1 Channels in Myelinated Hippocampal Axons

(2011) Chen Gu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activity-dependent Phosphorylation of Neuronal Kv2.1 Potassium Channels by CDK5

(2011) Oscar Cerda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cdk-mediated phosphorylation of the Kvβ2 auxiliary subunit regulates Kv1 channel axonal targeting

(2011) Hélène Vacher et al.   JOURNAL OF CELL BIOLOGY

Mutant LGI1 inhibits seizure-induced trafficking of Kv4.2 potassium channels

(2011) Stephen E. P. Smith et al.   JOURNAL OF NEUROCHEMISTRY

Voltage-Gated Na+ Channel  1B: A Secreted Cell Adhesion Molecule Involved in Human Epilepsy

(2011) G. A. Patino et al.   JOURNAL OF NEUROSCIENCE

Short- and Long-Term Plasticity at the Axon Initial Segment

(2011) M. S. Grubb et al.   JOURNAL OF NEUROSCIENCE

Neuronal trafficking of voltage-gated potassium channels

(2011) Camilla S. Jensen et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Distribution of M-channel subunits KCNQ2 and KCNQ3 in rat hippocampus

(2011) Felicia Klinger et al.   NEUROIMAGE

Diverse roles for auxiliary subunits in phosphorylation-dependent regulation of mammalian brain voltage-gated potassium channels

(2011) Helene Vacher et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Na+ Channel ? Subunits: Overachievers of the Ion Channel Family

(2011) William J. Brackenbury et al.   Frontiers in Pharmacology

Neurological Channelopathies

(2010) Dimitri M. Kullmann   Annual Review of Neuroscience

Molecular correlates of age-dependent seizures in an inherited neonatal-infantile epilepsy

(2010) Yunxiang Liao et al.   BRAIN

Building and maintaining the axon initial segment

(2010) Matthew S Grubb et al.   CURRENT OPINION IN NEUROBIOLOGY

A New Kv1.2 Channelopathy Underlying Cerebellar Ataxia

(2010) Gang Xie et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Formation of Heteromeric Kv2 Channels in Mammalian Brain Neurons

(2010) Yoshitaka Kihira et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus

(2010) Verena C. Wimmer et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunolocalization of the voltage-gated potassium channel Kv2.2 in GABAergic neurons in the basal forebrain of rats and mice

(2010) Tracey O. Hermanstyne et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Mining recent brain proteomic databases for ion channel phosphosite nuggets

(2010) Oscar Cerda et al.   JOURNAL OF GENERAL PHYSIOLOGY

Ca2+/Calmodulin Disrupts AKAP79/150 Interactions with KCNQ (M-Type) K+ Channels

(2010) M. Bal et al.   JOURNAL OF NEUROSCIENCE

ADAM22, A Kv1 Channel-Interacting Protein, Recruits Membrane-Associated Guanylate Kinases to Juxtaparanodes of Myelinated Axons

(2010) Y. Ogawa et al.   JOURNAL OF NEUROSCIENCE

NaV1.1 channels and epilepsy

(2010) William A. Catterall et al.   JOURNAL OF PHYSIOLOGY-LONDON

Sodium channel gene family: epilepsy mutations, gene interactions and modifier effects

(2010) Miriam H. Meisler et al.   JOURNAL OF PHYSIOLOGY-LONDON

Axon initial segment dysfunction in epilepsy

(2010) Verena C. Wimmer et al.   JOURNAL OF PHYSIOLOGY-LONDON

Multisite Phosphorylation of Voltage-Gated Sodium Channel α Subunits from Rat Brain

(2010) Frank J. Berendt et al.   JOURNAL OF PROTEOME RESEARCH

Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders

(2010) Massimo Mantegazza et al.   LANCET NEUROLOGY

Activity-dependent relocation of the axon initial segment fine-tunes neuronal excitability

(2010) Matthew S. Grubb et al.   NATURE

Presynaptic activity regulates Na+ channel distribution at the axon initial segment

(2010) Hiroshi Kuba et al.   NATURE

The axon initial segment and the maintenance of neuronal polarity

(2010) Matthew N. Rasband   NATURE REVIEWS NEUROSCIENCE

Temporal lobe epilepsy induces intrinsic alterations in Na channel gating in layer II medial entorhinal cortex neurons

(2010) Nicholas J. Hargus et al.   NEUROBIOLOGY OF DISEASE

SCN2A mutation associated with neonatal epilepsy, late-onset episodic ataxia, myoclonus, and pain

(2010) Y. Liao et al.   NEUROLOGY

Visual Deprivation Suppresses L5 Pyramidal Neuron Excitability by Preventing the Induction of Intrinsic Plasticity

(2010) Kiran Nataraj et al.   NEURON

Electrophysiology and beyond: Multiple roles of Na+ channel β subunits in development and disease

(2010) Gustavo A. Patino et al.   NEUROSCIENCE LETTERS

CaV2.1 channelopathies

(2010) Daniela Pietrobon   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

KV7 channelopathies

(2010) Snezana Maljevic et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Dynamics of Kv1 Channel Transport in Axons

(2010) Yuanzheng Gu et al.   PLoS One

Determinants of voltage-gated sodium channel clustering in neurons

(2010) Christophe Leterrier et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Made for “anchorin”: Kv7.2/7.3 (KCNQ2/KCNQ3) channels and the modulation of neuronal excitability in vertebrate axons

(2010) Edward C. Cooper   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Composition, assembly, and maintenance of excitable membrane domains in myelinated axons

(2010) Matthew N. Rasband   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The Kv2.1 K+ channel targets to the axon initial segment of hippocampal and cortical neurons in culture and in situ

(2009) Patrick D Sarmiere et al.   BMC NEUROSCIENCE

Long-term increasing co-localization of SCN8A and ankyrin-G in rat hippocampal cornu ammonis 1 after pilocarpine induced status epilepticus

(2009) Ziyi Chen et al.   BRAIN RESEARCH

Episodic ataxia type 1 mutations differentially affect neuronal excitability and transmitter release

(2009) J. H. Heeroma et al.   Disease Models & Mechanisms

A rescuable folding defective Nav1.1 (SCN1A) sodium channel mutant causes GEFS+: Common mechanism in Nav1.1 related epilepsies?

(2009) Raffaella Rusconi et al.   HUMAN MUTATION

Potassium Channel Modulation by a Toxin Domain in Matrix Metalloprotease 23

(2009) Srikant Rangaraju et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calmodulin Activation Limits the Rate of KCNQ2 K+Channel Exit from the Endoplasmic Reticulum

(2009) Alessandro Alaimo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Functional Characterization of Protein Kinase A-catalyzed Phosphorylation of Potassium Channel Kv1.2 at Serine 449

(2009) Rosalyn P. Johnson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cell-Type-Dependent Molecular Composition of the Axon Initial Segment

(2009) A. Lorincz et al.   JOURNAL OF NEUROSCIENCE

A Functional Null Mutation of SCN1B in a Patient with Dravet Syndrome

(2009) G. A. Patino et al.   JOURNAL OF NEUROSCIENCE

Distinct contributions of Nav1.6 and Nav1.2 in action potential initiation and backpropagation

(2009) Wenqin Hu et al.   NATURE NEUROSCIENCE

Electrogenic Tuning of the Axon Initial Segment

(2009) Brian D. Clark et al.   NEUROSCIENTIST

Impaired NaV1.2 function and reduced cell surface expression in benign familial neonatal-infantile seizures

(2008) Sunita N. Misra et al.   EPILEPSIA

Identification of an Evolutionarily Conserved Extracellular Threonine Residue Critical for Surface Expression and Its Potential Coupling of Adjacent Voltage-sensing and Gating Domains in Voltage-gated Potassium Channels

(2008) Lynn Mckeown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein kinase CK2 contributes to the organization of sodium channels in axonal membranes by regulating their interactions with ankyrin G

(2008) Aline Bréchet et al.   JOURNAL OF CELL BIOLOGY

Postsynaptic Density-93 Clusters Kv1 Channels at Axon Initial Segments Independently of Caspr2

(2008) Y. Ogawa et al.   JOURNAL OF NEUROSCIENCE

Initial segment Kv2.2 channels mediate a slow delayed rectifier and maintain high frequency action potential firing in medial nucleus of the trapezoid body neurons

(2008) Jamie Johnston et al.   JOURNAL OF PHYSIOLOGY-LONDON

The C-terminus of Kv7 channels: a multifunctional module

(2008) Yoni Haitin et al.   JOURNAL OF PHYSIOLOGY-LONDON

Nav1.1 is predominantly expressed in nodes of Ranvier and axon initial segments

(2008) Amandine Duflocq et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Action potential initiation and propagation: Upstream influences on neurotransmission

(2008) G.J. Kress et al.   NEUROSCIENCE

Localization and Targeting of Voltage-Dependent Ion Channels in Mammalian Central Neurons

(2008) Helene Vacher et al.   PHYSIOLOGICAL REVIEWS

Calmodulin regulates the trafficking of KCNQ2 potassium channels

(2007) Ainhoa Etxeberria et al.   FASEB JOURNAL