MTA family of proteins in DNA damage response: mechanistic insights and potential applications

Mta2 promotes Tipin-dependent maintenance of replication fork integrity

(2014) Alessia Errico et al.   CELL CYCLE

The Chromatin Response to DNA Breaks: Leaving a Mark on Genome Integrity

(2013) Godelieve Smeenk et al.   Annual Review of Biochemistry

CHD4 in the DNA-damage response and cell cycle progression: not so NuRDy now

(2013) Aoife O’Shaughnessy et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice

(2013) O. M. Dovey et al.   BLOOD

Chromatin Remodeling at DNA Double-Strand Breaks

(2013) Brendan D. Price et al.   CELL

Repression of NR4A1 by a chromatin modifier promotes docetaxel resistance in PC-3 human prostate cancer cells

(2013) Liang Yu et al.   FEBS LETTERS

Checkpoint kinases and the INO80 nucleosome remodeling complex enhance global chromatin mobility in response to DNA damage

(2013) A. Seeber et al.   GENES & DEVELOPMENT

Connecting Chromatin Modifying Factors to DNA Damage Response

(2013) Weiwei Lai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Histone Deacetylase Regulation of ATM-Mediated DNA Damage Signaling

(2013) K. T. Thurn et al.   MOLECULAR CANCER THERAPEUTICS

SIRT6 Recruits SNF2H to DNA Break Sites, Preventing Genomic Instability through Chromatin Remodeling

(2013) Debra Toiber et al.   MOLECULAR CELL

The ATM protein kinase: regulating the cellular response to genotoxic stress and more

(2013) Yosef Shiloh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nuclear Localization of the Transcriptional Regulator MIER1α Requires Interaction with HDAC1/2 in Breast Cancer Cells

(2013) Shengnan Li et al.   PLoS One

Landscape of somatic single-nucleotide and copy-number mutations in uterine serous carcinoma

(2013) S. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylases 1 and 2 maintain S-phase chromatin and DNA replication fork progression

(2013) Srividya Bhaskara et al.   Epigenetics & Chromatin

The MTA family proteins as novel histone H3 binding proteins

(2013) Meng Wu et al.   Cell and Bioscience

Metastasis-Associated Protein 1/Nucleosome Remodeling and Histone Deacetylase Complex in Cancer

(2012) D.-Q. Li et al.   CANCER RESEARCH

Structure and function of the BAH domain in chromatin biology

(2012) Na Yang et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Close encounters of the RNF8th kind: when chromatin meets DNA repair

(2012) Martijn S Luijsterburg et al.   CURRENT OPINION IN CELL BIOLOGY

A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

(2012) Martijn S Luijsterburg et al.   EMBO JOURNAL

Chromodomain Helicase DNA-binding Protein 4 (CHD4) Regulates Homologous Recombination DNA Repair, and Its Deficiency Sensitizes Cells to Poly(ADP-ribose) Polymerase (PARP) Inhibitor Treatment

(2012) Mei-Ren Pan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prime, Repair, Restore: The Active Role of Chromatin in the DNA Damage Response

(2012) Gaston Soria et al.   MOLECULAR CELL

The BAH domain of ORC1 links H4K20me2 to DNA replication licensing and Meier–Gorlin syndrome

(2012) Alex J. Kuo et al.   NATURE

ATP-dependent chromatin remodeling in the DNA-damage response

(2012) Hannes Lans et al.   Epigenetics & Chromatin

Heterochromatin and the DNA damage response: the need to relaxThis paper is one of a selection of papers in a Special Issue entitled 31st Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal’s usual peer review process.

(2011) Kendra L. Cann et al.   Biochemistry and Cell Biology

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Mi-2/NuRD complex function is required for normal S phase progression and assembly of pericentric heterochromatin

(2011) Jennifer K. Sims et al.   MOLECULAR BIOLOGY OF THE CELL

Chromatin and the DNA damage response: The cancer connection

(2011) Martijn S. Luijsterburg et al.   Molecular Oncology

The MRE11 complex: starting from the ends

(2011) Travis H. Stracker et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Activation of Hif1α by the Prolylhydroxylase Inhibitor Dimethyoxalyglycine Decreases Radiosensitivity

(2011) Marina K. Ayrapetov et al.   PLoS One

Chromatin response to DNA double-strand break damage

(2011) Yunhe Bao   Epigenomics

NuRD alert! NuRD regulates the DNA damage response

(2011) Godelieve Smeenk et al.   Epigenomics

Hdac3 Is Essential for the Maintenance of Chromatin Structure and Genome Stability

(2010) Srividya Bhaskara et al.   CANCER CELL

Mi-2/NuRD complex making inroads into DNA-damage response pathway

(2010) Da-Qiang Li et al.   CELL CYCLE

Histone Post-Translational Modifications in DNA Damage Response

(2010) L. Méndez-Acuña et al.   CYTOGENETIC AND GENOME RESEARCH

Regulation of DNA-damage responses and cell-cycle progression by the chromatin remodelling factor CHD4

(2010) Sophie E Polo et al.   EMBO JOURNAL

A cooperative activation loop among SWI/SNF, γ-H2AX and H3 acetylation for DNA double-strand break repair

(2010) Han-Sae Lee et al.   EMBO JOURNAL

Chromatin dynamics coupled to DNA repair

(2010) Dori Huertas et al.   Epigenetics

Revelation of p53-independent Function of MTA1 in DNA Damage Response via Modulation of the p21WAF1-Proliferating Cell Nuclear Antigen Pathway

(2010) Da-Qiang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Requirement of MTA1 in ATR-mediated DNA Damage Checkpoint Function

(2010) Da-Qiang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The p400 ATPase regulates nucleosome stability and chromatin ubiquitination during DNA repair

(2010) Ye Xu et al.   JOURNAL OF CELL BIOLOGY

The NuRD chromatin–remodeling complex regulates signaling and repair of DNA damage

(2010) Godelieve Smeenk et al.   JOURNAL OF CELL BIOLOGY

The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damage

(2010) Dorthe Helena Larsen et al.   JOURNAL OF CELL BIOLOGY

The DNA Damage Response: Making It Safe to Play with Knives

(2010) Alberto Ciccia et al.   MOLECULAR CELL

Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining

(2010) Kyle M Miller et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage

(2010) D. M. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Biology of Chromatin Remodeling Complexes

(2009) Cedric R. Clapier et al.   Annual Review of Biochemistry

MTA1 Coregulator Regulates p53 Stability and Function

(2009) Da-Qiang Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CBP/p300-mediated acetylation of histone H3 on lysine 56

(2009) Chandrima Das et al.   NATURE

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Chromatin remodeling finds its place in the DNA double-strand break response

(2009) T. K. Pandita et al.   NUCLEIC ACIDS RESEARCH

E3 ubiquitin ligase COP1 regulates the stability and functions of MTA1

(2009) D.-Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice

(2008) Rui-Hong Wang et al.   CANCER CELL

Acetylated Lysine 56 on Histone H3 Drives Chromatin Assembly after Repair and Signals for the Completion of Repair

(2008) Chin-Chuan Chen et al.   CELL

Mammalian SWI/SNF chromatin remodeling complexes are required to prevent apoptosis after DNA damage

(2008) Ji-Hye Park et al.   DNA REPAIR

Atrophin recruits HDAC1/2 and G9a to modify histone H3K9 and to determine cell fates

(2008) Lei Wang et al.   EMBO REPORTS

ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin

(2008) Aaron A. Goodarzi et al.   MOLECULAR CELL

ATR: an essential regulator of genome integrity

(2008) Karlene A. Cimprich et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

 -H2AX in recognition and signaling of DNA double-strand breaks in the context of chromatin

(2008) A. Kinner et al.   NUCLEIC ACIDS RESEARCH