Heterochromatin and the DNA damage response: the need to relaxThis paper is one of a selection of papers in a Special Issue entitled 31st Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal’s usual peer review process.

Why cells respond differently to DNA damage: A chromatin perspective

(2011) Oscar Fernandez-Capetillo et al.   CELL CYCLE

DNA damage response activation in mouse embryonic fibroblasts undergoing replicative senescence and following spontaneous immortalization

(2011) Raffaella Di Micco et al.   CELL CYCLE

Mobilization and recruitment of HP1β: A bimodal response to DNA breakage

(2011) Nabieh Ayoub et al.   CELL CYCLE

γH2AX foci analysis for monitoring DNA double-strand break repair: Strengths, limitations and optimization

(2011) Markus Löbrich et al.   CELL CYCLE

Tip60: Connecting chromatin to DNA damage signaling

(2011) Yingli Sun et al.   CELL CYCLE

Physical interaction between the histone acetyl transferase Tip60 and the DNA double-strand breaks sensor MRN complex

(2010) Catherine Chailleux et al.   BIOCHEMICAL JOURNAL

Residual γH2AX foci as an indication of lethal DNA lesions

(2010) Judit P Banáth et al.   BMC CANCER

Paving the way for H2AX phosphorylation: Chromatin changes in the DNA damage response

(2010) Nabieh Ayoub et al.   CELL CYCLE

High resolution imaging of changes in the structure and spatial organization of chromatin, γ-H2A.X and the MRN complex within etoposide-induced DNA repair foci

(2010) Graham Dellaire et al.   CELL CYCLE

Higher-order chromatin structure in DSB induction, repair and misrepair

(2010) Martin Falk et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair

(2010) Angela T. Noon et al.   NATURE CELL BIOLOGY

Chromosome Territories

(2010) T. Cremer et al.   Cold Spring Harbor Perspectives in Biology

The impact of heterochromatin on DSB repair

(2009) Aaron A. Goodarzi et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

The RIDDLE Syndrome Protein Mediates a Ubiquitin-Dependent Signaling Cascade at Sites of DNA Damage

(2009) Grant S. Stewart et al.   CELL

γ-radiation-induced γH2AX formation occurs preferentially in actively transcribing euchromatic loci

(2009) Raja S. Vasireddy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The nuclear envelope—a scaffold for silencing?

(2009) Benjamin D Towbin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Recruitment of heterochromatin protein 1 to DNA repair sites

(2009) Miroslaw Zarebski et al.   CYTOMETRY PART A

Regulatory ubiquitylation in response to DNA double-strand breaks

(2009) Stephanie Panier et al.   DNA REPAIR

ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2

(2009) Andrea Beucher et al.   EMBO JOURNAL

DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions

(2009) Suhasni Gopalakrishnan et al.   HUMAN MOLECULAR GENETICS

Role of A-type lamins in signaling, transcription, and chromatin organization

(2009) Vicente Andrés et al.   JOURNAL OF CELL BIOLOGY

Heterochromatin protein 1 is recruited to various types of DNA damage

(2009) Martijn S. Luijsterburg et al.   JOURNAL OF CELL BIOLOGY

The Emerging Role of HP1 in the DNA Damage Response

(2009) C. Dinant et al.   MOLECULAR AND CELLULAR BIOLOGY

Monomethylation of Histone H4-Lysine 20 Is Involved in Chromosome Structure and Stability and Is Essential for Mouse Development

(2009) H. Oda et al.   MOLECULAR AND CELLULAR BIOLOGY

Type II topoisomerases--inhibitors, repair mechanisms and mutations

(2009) P. Heisig   MUTAGENESIS

Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60

(2009) Yingli Sun et al.   NATURE CELL BIOLOGY

The emerging role of nuclear architecture in DNA repair and genome maintenance

(2009) Tom Misteli et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chromatin remodelling beyond transcription: the INO80 and SWR1 complexes

(2009) Ashby J Morrison et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Heterochromatic Genome Stability Requires Regulators of Histone H3 K9 Methylation

(2009) Jamy C. Peng et al.   PLoS Genetics

Histones: Annotating Chromatin

(2008) Eric I. Campos et al.   Annual Review of Genetics

ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation

(2008) Melanie Ehrlich et al.   AUTOIMMUNITY

Chromatin structure influences the sensitivity of DNA to γ-radiation

(2008) Martin Falk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Growth of persistent foci of DNA damage checkpoint factors is essential for amplification of G1 checkpoint signaling

(2008) Motohiro Yamauchi et al.   DNA REPAIR

PP4 is a γH2AX phosphatase required for recovery from the DNA damage checkpoint

(2008) Shinichiro Nakada et al.   EMBO REPORTS

Epigenetics regulate centromere formation and kinetochore function

(2008) Randall S. Gieni et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin

(2008) Aaron A. Goodarzi et al.   MOLECULAR CELL

FACT-Mediated Exchange of Histone Variant H2AX Regulated by Phosphorylation of H2AX and ADP-Ribosylation of Spt16

(2008) Kyu Heo et al.   MOLECULAR CELL

Linking Heterochromatin Protein 1 (HP1) to cancer progression

(2008) George K. Dialynas et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Perturbation of HP1 localization and chromatin binding ability causes defects in sister-chromatid cohesion

(2008) Akira Inoue et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

HP1-β mobilization promotes chromatin changes that initiate the DNA damage response

(2008) Nabieh Ayoub et al.   NATURE

Structural insights into human KAP1 PHD finger–bromodomain and its role in gene silencing

(2008) Lei Zeng et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Putting a KAP on Transcription and Stress

(2008) Mark D. Alter et al.   NEURON