Single-Domain Antibody-SH3 Fusions for Efficient Neutralization of HIV-1 Nef Functions

Inhibition of the Nef regulatory protein of HIV-1 by a single-domain antibody

(2011) J. Bouchet et al.   BLOOD

Mechanisms of HIV-1 Nef Function and Intracellular Signaling

(2011) John L. Foster et al.   Journal of Neuroimmune Pharmacology

Molecular Design, Functional Characterization and Structural Basis of a Protein Inhibitor Against the HIV-1 Pathogenicity Factor Nef

(2011) Sebastian Breuer et al.   PLoS One

Conformation of the Dileucine-Based Sorting Motif in HIV-1 Nef Revealed by Intermolecular Domain Assembly

(2011) Florian A. Horenkamp et al.   TRAFFIC

Inhibition of phagocytosis in HIV-1-infected macrophages relies on Nef-dependent alteration of focal delivery of recycling compartments

(2010) J. Mazzolini et al.   BLOOD

Macrophage podosomes go 3D

(2010) Emeline Van Goethem et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

HIV-1 Nef Triggers Macrophage Fusion in a p61Hck- and Protease-Dependent Manner

(2010) C. Verollet et al.   JOURNAL OF IMMUNOLOGY

Human immunodeficiency virus (HIV) type-1, HIV-2 and simian immunodeficiency virus Nef proteins

(2010) Nadine Laguette et al.   MOLECULAR ASPECTS OF MEDICINE

Small Molecule Inhibition of HIV-1–Induced MHC-I Down-Regulation Identifies a Temporally Regulated Switch in Nef Action

(2010) Jimmy D. Dikeakos et al.   MOLECULAR BIOLOGY OF THE CELL

Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis

(2009) C. Cougoule et al.   BLOOD

Matrix Architecture Dictates Three-Dimensional Migration Modes of Human Macrophages: Differential Involvement of Proteases and Podosome-Like Structures

(2009) E. Van Goethem et al.   JOURNAL OF IMMUNOLOGY

Nef-Induced CD4 Endocytosis in Human Immunodeficiency Virus Type 1 Host Cells: Role of p56lck Kinase

(2009) N. Laguette et al.   JOURNAL OF VIROLOGY

Inhibition of T-Cell Receptor-Induced Actin Remodeling and Relocalization of Lck Are Evolutionarily Conserved Activities of Lentiviral Nef Proteins

(2009) J. M. Rudolph et al.   JOURNAL OF VIROLOGY

HIV-1 evades virus-specific IgG2 and IgA responses by targeting systemic and intestinal B cells via long-range intercellular conduits

(2009) Weifeng Xu et al.   NATURE IMMUNOLOGY

Molecular mediators of macrophage fusion

(2009) Laura Helming et al.   TRENDS IN CELL BIOLOGY

Hematopoietic cell kinase (Hck) isoforms and phagocyte duties – From signaling and actin reorganization to migration and phagocytosis

(2008) R GUIET et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Human Immunodeficiency Virus Type 1 Nef Incorporation into Virions Does Not Increase Infectivity

(2008) N. Laguette et al.   JOURNAL OF VIROLOGY