Macrophage Mesenchymal Migration Requires Podosome Stabilization by Filamin A

Degrading Devices: Invadosomes in Proteolytic Cell Invasion

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Molecular Genetics of Neuronal Migration Disorders

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Extracellular proteolysis in macrophage migration: Losing grip for a breakthrough

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Podosomal proteins as causes of human syndromes: A role in craniofacial development?

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The filamins

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The plasticity of cytoskeletal dynamics underlying neoplastic cell migration

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Macrophage podosomes go 3D

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Filamin A mediates interactions between cytoskeletal proteins that control cell adhesion

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Dendritic cell podosomes are protrusive and invade the extracellular matrix using metalloproteinase MMP-14

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Filamin A regulates focal adhesion disassembly and suppresses breast cancer cell migration and invasion

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HIV-1 Nef Triggers Macrophage Fusion in a p61Hck- and Protease-Dependent Manner

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Loss of Klotho during melanoma progression leads to increased filamin cleavage, increased Wnt5A expression, and enhanced melanoma cell motility

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Dynamics of podosome stiffness revealed by atomic force microscopy

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Filamins in cell signaling, transcription and organ development

(2010) Alex-Xianghua Zhou et al.   TRENDS IN CELL BIOLOGY

Three-dimensional migration of macrophages requires Hck for podosome organization and extracellular matrix proteolysis

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TGF -induced endothelial podosomes mediate basement membrane collagen degradation in arterial vessels

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Podosome-like structures of non-invasive carcinoma cells are replaced in epithelial-mesenchymal transition by actin comet-embedded invadopodia

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Matrix Architecture Dictates Three-Dimensional Migration Modes of Human Macrophages: Differential Involvement of Proteases and Podosome-Like Structures

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Filamin A–β1 Integrin Complex Tunes Epithelial Cell Response to Matrix Tension

(2009) Scott Gehler et al.   MOLECULAR BIOLOGY OF THE CELL

ASB2 targets filamins A and B to proteasomal degradation

(2008) M. L. Heuze et al.   BLOOD

Hematopoietic cell kinase (Hck) isoforms and phagocyte duties – From signaling and actin reorganization to migration and phagocytosis

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Lifeact: a versatile marker to visualize F-actin

(2008) Julia Riedl et al.   NATURE METHODS

Trouble making the first move: interpreting arrested neuronal migration in the cerebral cortex

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Paxillin Phosphorylation Controls Invadopodia/Podosomes Spatiotemporal Organization

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The Tyrosine Kinase Activity of c-Src Regulates Actin Dynamics and Organization of Podosomes in Osteoclasts

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