The multiple faces of leukocyte interstitial migration

Neutrophil migration: moving from zebrafish models to human autoimmunity

(2014) Miriam A. Shelef et al.   IMMUNOLOGICAL REVIEWS

Migration of dendritic cells: physical principles, molecular mechanisms, and functional implications

(2014) Mélina L. Heuzé et al.   IMMUNOLOGICAL REVIEWS

Lymphocyte Electrotaxis In Vitro and In Vivo

(2014) F. Lin et al.   JOURNAL OF IMMUNOLOGY

Wiskott-Aldrich syndrome: a comprehensive review

(2013) Michel J. Massaad et al.   Annals of the New York Academy of Sciences

The integrin coactivator Kindlin-3 is not required for lymphocyte diapedesis

(2013) S. J. Cohen et al.   BLOOD

DOCK8 is critical for the survival and function of NKT cells

(2013) G. Crawford et al.   BLOOD

Matrix metalloproteinases modulate ameboid-like migration of neutrophils through inflamed interstitial tissue

(2013) M. Lerchenberger et al.   BLOOD

Dimensions in cell migration

(2013) Andrew D Doyle et al.   CURRENT OPINION IN CELL BIOLOGY

DOCK8 Immune Deficiency as a Model for Primary Cytoskeletal Dysfunction

(2013) Sean A. McGhee et al.   DISEASE MARKERS

A role for LFA-1 in delaying T-lymphocyte egress from lymph nodes

(2013) Peter Reichardt et al.   EMBO JOURNAL

Defects of leukocyte migration in primary immunodeficiencies

(2013) Raffaele Badolato   EUROPEAN JOURNAL OF IMMUNOLOGY

The future of immunoimaging - Deeper, bigger, more precise, and definitively more colorful

(2013) Jianyong Tang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The Transcription Factor NFAT Exhibits Signal Memory during Serial T Cell Interactions with Antigen-Presenting Cells

(2013) Francesco Marangoni et al.   IMMUNITY

Distinct signaling mechanisms regulate migration in unconfined versus confined spaces

(2013) Wei-Chien Hung et al.   JOURNAL OF CELL BIOLOGY

Physical limits of cell migration: Control by ECM space and nuclear deformation and tuning by proteolysis and traction force

(2013) Katarina Wolf et al.   JOURNAL OF CELL BIOLOGY

Dermal Regulatory T Cells Display Distinct Migratory Behavior That Is Modulated during Adaptive and Innate Inflammation

(2013) Z. Chow et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cells Regulate High-Speed Interstitial T Cell Migration in the Lymph Node via LFA-1/ICAM-1

(2013) T. Katakai et al.   JOURNAL OF IMMUNOLOGY

Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo

(2013) Tim Lämmermann et al.   NATURE

Matrix geometry determines optimal cancer cell migration strategy and modulates response to interventions

(2013) Melda Tozluoğlu et al.   NATURE CELL BIOLOGY

Inflammation-induced interstitial migration of effector CD4+ T cells is dependent on integrin αV

(2013) Michael G Overstreet et al.   NATURE IMMUNOLOGY

Real-time in vivo analysis of T cell activation in the central nervous system using a genetically encoded calcium indicator

(2013) Marsilius Mues et al.   NATURE MEDICINE

A combination of fluorescent NFAT and H2B sensors uncovers dynamics of T cell activation in real time during CNS autoimmunity

(2013) Dmitri Lodygin et al.   NATURE MEDICINE

Geometric Friction Directs Cell Migration

(2013) M. Le Berre et al.   PHYSICAL REVIEW LETTERS

Intravital Immunofluorescence for Visualizing the Microcirculatory and Immune Microenvironments in the Mouse Ear Dermis

(2013) Witold W. Kilarski et al.   PLoS One

Filamin-A Regulates Neutrophil Uropod Retraction through RhoA during Chemotaxis

(2013) Chunxiang Sun et al.   PLoS One

Biased migration of confined neutrophil-like cells in asymmetric hydraulic environments

(2013) H. V. Prentice-Mott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interstitial Dendritic Cell Guidance by Haptotactic Chemokine Gradients

(2013) M. Weber et al.   SCIENCE

Mechanisms of leading edge protrusion in interstitial migration

(2013) Kerry Wilson et al.   Nature Communications

DOCK8 deficiency

(2012) Helen C. Su et al.   Annals of the New York Academy of Sciences

Differential requirement for ROCK in dendritic cell migration within lymphatic capillaries in steady-state and inflammation

(2012) M. Nitschke et al.   BLOOD

Cdc42 regulates neutrophil migration via crosstalk between WASp, CD11b, and microtubules

(2012) S. Kumar et al.   BLOOD

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

(2012) Y. Harada et al.   BLOOD

Microfluidic kit-on-a-lid: a versatile platform for neutrophil chemotaxis assays

(2012) E. K. Sackmann et al.   BLOOD

Blood leukocytes and macrophages of various phenotypes have distinct abilities to form podosomes and to migrate in 3D environments

(2012) Céline Cougoule et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Podoplanin-Rich Stromal Networks Induce Dendritic Cell Motility via Activation of the C-type Lectin Receptor CLEC-2

(2012) Sophie E. Acton et al.   IMMUNITY

Uropod elongation is a common final step in leukocyte extravasation through inflamed vessels

(2012) Young-Min Hyun et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Rho-Family GTPase Cdc42 Controls Migration of Langerhans Cells In Vivo

(2012) N. Luckashenak et al.   JOURNAL OF IMMUNOLOGY

Nanotopography-Guided Migration of T Cells

(2012) K. W. Kwon et al.   JOURNAL OF IMMUNOLOGY

PI3Ks and small GTPases in neutrophil migration: Two sides of the same coin

(2012) Giulia Germena et al.   MOLECULAR IMMUNOLOGY

Visualization of splenic marginal zone B-cell shuttling and follicular B-cell egress

(2012) Tal I. Arnon et al.   NATURE

Body-barrier surveillance by epidermal γδ TCRs

(2012) Grzegorz Chodaczek et al.   NATURE IMMUNOLOGY

Capillary and arteriolar pericytes attract innate leukocytes exiting through venules and 'instruct' them with pattern-recognition and motility programs

(2012) Konstantin Stark et al.   NATURE IMMUNOLOGY

Dynamic migration of    intraepithelial lymphocytes requires occludin

(2012) K. L. Edelblum et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo

(2012) M. R. Gaiser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tissue-resident memory CD8+ T cells continuously patrol skin epithelia to quickly recognize local antigen

(2012) S. Ariotti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Decade of Imaging Cellular Motility and Interaction Dynamics in the Immune System

(2012) R. N. Germain et al.   SCIENCE

Dissecting T Cell Contraction In Vivo Using a Genetically Encoded Reporter of Apoptosis

(2012) Kym R. Garrod et al.   Cell Reports

The human cytokine TSLP triggers a cell-autonomous dendritic cell migration in confined environments

(2011) M.-I. Fernandez et al.   BLOOD

Constitutively active ezrin increases membrane tension, slows migration, and impedes endothelial transmigration of lymphocytes in vivo in mice

(2011) Y. Liu et al.   BLOOD

Drosophila embryonic hemocytes

(2011) Iwan Robert Evans et al.   CURRENT BIOLOGY

DOCK8 is essential for T-cell survival and the maintenance of CD8+ T-cell memory

(2011) Teresa Lambe et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Intravital Imaging Reveals Limited Antigen Presentation and T Cell Effector Function in Mycobacterial Granulomas

(2011) Jackson G. Egen et al.   IMMUNITY

The Signaling Adaptor Eps8 Is an Essential Actin Capping Protein for Dendritic Cell Migration

(2011) Emanuela Frittoli et al.   IMMUNITY

Cortactin deficiency is associated with reduced neutrophil recruitment but increased vascular permeability in vivo

(2011) Michael Schnoor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

DC mobilization from the skin requires docking to immobilized CCL21 on lymphatic endothelium and intralymphatic crawling

(2011) Orna Tal et al.   JOURNAL OF EXPERIMENTAL MEDICINE

DOCK8 deficiency impairs CD8 T cell survival and function in humans and mice

(2011) Katrina L. Randall et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Identification of a Motile IL-17-Producing    T Cell Population in the Dermis

(2011) E. E. Gray et al.   JOURNAL OF IMMUNOLOGY

Sphingosine 1-Phosphate-Induced Motility and Endocytosis of Dendritic Cells Is Regulated by SWAP-70 through RhoA

(2011) C. Ocana-Morgner et al.   JOURNAL OF IMMUNOLOGY

In Vivo Analysis of Uropod Function during Physiological T Cell Trafficking

(2011) S. F. Soriano et al.   JOURNAL OF IMMUNOLOGY

Fascin1 Promotes Cell Migration of Mature Dendritic Cells

(2011) Y. Yamakita et al.   JOURNAL OF IMMUNOLOGY

In Vivo Imaging of T-Cell Motility in the Elicitation Phase of Contact Hypersensitivity Using Two-Photon Microscopy

(2011) Gyohei Egawa et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Different patterns of peripheral migration by memory CD4+ and CD8+ T cells

(2011) Thomas Gebhardt et al.   NATURE

Lyn is a redox sensor that mediates leukocyte wound attraction in vivo

(2011) Sa Kan Yoo et al.   NATURE

Afferent lymph–derived T cells and DCs use different chemokine receptor CCR7–dependent routes for entry into the lymph node and intranodal migration

(2011) Asolina Braun et al.   NATURE IMMUNOLOGY

Visualizing the innate and adaptive immune responses underlying allograft rejection by two-photon microscopy

(2011) Susanna Celli et al.   NATURE MEDICINE

A three-dimensional organotypic assay to measure target cell killing by cytotoxic T lymphocytes

(2010) Bettina Weigelin et al.   BIOCHEMICAL PHARMACOLOGY

Rho-mDia1 pathway is required for adhesion, migration, and T-cell stimulation in dendritic cells

(2010) H. Tanizaki et al.   BLOOD

Critical roles for Rac GTPases in T-cell migration to and within lymph nodes

(2010) M. Faroudi et al.   BLOOD

Comprehensive analysis of lymph node stroma-expressed Ig superfamily members reveals redundant and nonredundant roles for ICAM-1, ICAM-2, and VCAM-1 in lymphocyte homing

(2010) R. T. Boscacci et al.   BLOOD

Germinal Center Dynamics Revealed by Multiphoton Microscopy with a Photoactivatable Fluorescent Reporter

(2010) Gabriel D. Victora et al.   CELL

Breaking ranks: how leukocytes react to developmental cues and tissue injury

(2010) Francesca Peri   CURRENT OPINION IN GENETICS & DEVELOPMENT

Differential Regulation of Protrusion and Polarity by PI(3)K during Neutrophil Motility in Live Zebrafish

(2010) Sa Kan Yoo et al.   DEVELOPMENTAL CELL

Cancer Dissemination—Lessons from Leukocytes

(2010) Chris D. Madsen et al.   DEVELOPMENTAL CELL

An MEK-cofilin signalling module controls migration of human T cells in 3D but not 2D environments

(2010) Martin Klemke et al.   EMBO JOURNAL

Mechanisms of force generation and force transmission during interstitial leukocyte migration

(2010) Jörg Renkawitz et al.   EMBO REPORTS

Immobilized Chemokine Fields and Soluble Chemokine Gradients Cooperatively Shape Migration Patterns of Dendritic Cells

(2010) Kathrin Schumann et al.   IMMUNITY

Integrin-Induced PIP5K1C Kinase Polarization Regulates Neutrophil Polarization, Directionality, and In Vivo Infiltration

(2010) Wenwen Xu et al.   IMMUNITY

Trafficking of immune cells in the central nervous system

(2010) Emma H. Wilson et al.   JOURNAL OF CLINICAL INVESTIGATION

Confinement-optimized three-dimensional T cell amoeboid motility is modulated via myosin IIA–regulated adhesions

(2010) Jordan Jacobelli et al.   NATURE IMMUNOLOGY

Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II

(2010) Hyota Takamatsu et al.   NATURE IMMUNOLOGY

B cell follicles and antigen encounters of the third kind

(2010) Jason G Cyster   NATURE IMMUNOLOGY

Subcellular dynamics of T cell immunological synapses and kinapses in lymph nodes

(2010) Georges A. Azar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dictyostelium amoebae and neutrophils can swim

(2010) N. P. Barry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell-autonomous and environmental contributions to the interstitial migration of T cells

(2010) Paulus Mrass et al.   Seminars in Immunopathology

Knocking at the brain’s door: intravital two-photon imaging of autoreactive T cell interactions with CNS structures

(2010) Naoto Kawakami et al.   Seminars in Immunopathology

The Ins and Outs of Leukocyte Integrin Signaling

(2009) Clare L. Abram et al.   Annual Review of Immunology

Functional Anatomy of T Cell Activation and Synapse Formation

(2009) David R. Fooksman et al.   Annual Review of Immunology

Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration

(2009) T. Lammermann et al.   BLOOD

Cytohesin-1 controls the activation of RhoA and modulates integrin-dependent adhesion and migration of dendritic cells

(2009) T. Quast et al.   BLOOD

Distinct roles for LFA-1 affinity regulation during T-cell adhesion, diapedesis, and interstitial migration in lymph nodes

(2009) E. J. Park et al.   BLOOD

ROCK1 functions as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability

(2009) S. Vemula et al.   BLOOD

A Dynamic Map of Antigen Recognition by CD4 T Cells at the Site of Leishmania major Infection

(2009) Orchidée Filipe-Santos et al.   Cell Host & Microbe

Mechanical modes of ‘amoeboid’ cell migration

(2009) Tim Lämmermann et al.   CURRENT OPINION IN CELL BIOLOGY

Behavior of Parasite-Specific Effector CD8+ T Cells in the Brain and Visualization of a Kinesis-Associated System of Reticular Fibers

(2009) Emma H. Wilson et al.   IMMUNITY

Large deletions and point mutations involving the dedicator of cytokinesis 8 (DOCK8) in the autosomal-recessive form of hyper-IgE syndrome

(2009) Karin R. Engelhardt et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Regulation of Immature Dendritic Cell Migration by RhoA Guanine Nucleotide Exchange Factor Arhgef5

(2009) Zhenglong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plasticity of cell migration: a multiscale tuning model

(2009) Peter Friedl et al.   JOURNAL OF CELL BIOLOGY

Preformed portals facilitate dendritic cell entry into afferent lymphatic vessels

(2009) Holger Pflicke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Myosin-IIA and ICAM-1 Regulate the Interchange between Two Distinct Modes of T Cell Migration

(2009) J. Jacobelli et al.   JOURNAL OF IMMUNOLOGY

The mDial Formin Is Required for Neutrophil Polarization, Migration, and Activation of the LARG/RhoA/ROCK Signaling Axis during Chemotaxis

(2009) Y. Shi et al.   JOURNAL OF IMMUNOLOGY

Matrix Architecture Dictates Three-Dimensional Migration Modes of Human Macrophages: Differential Involvement of Proteases and Podosome-Like Structures

(2009) E. Van Goethem et al.   JOURNAL OF IMMUNOLOGY

Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions

(2009) Ingo Bartholomäus et al.   NATURE

Adaptive force transmission in amoeboid cell migration

(2009) Jörg Renkawitz et al.   NATURE CELL BIOLOGY

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production

(2009) Katrina L Randall et al.   NATURE IMMUNOLOGY

Combined Immunodeficiency Associated withDOCK8Mutations

(2009) Qian Zhang et al.   NEW ENGLAND JOURNAL OF MEDICINE

In Vivo Imaging and Quantitative Analysis of Leukocyte Directional Migration and Polarization in Inflamed Tissue

(2009) Alexander Georg Khandoga et al.   PLoS One

ITAM Signaling by Vav Family Rho Guanine Nucleotide Exchange Factors Regulates Interstitial Transit Rates of Neutrophils In Vivo

(2009) Daniel B. Graham et al.   PLoS One

Sequential Regulation of DOCK2 Dynamics by Two Phospholipids During Neutrophil Chemotaxis

(2009) A. Nishikimi et al.   SCIENCE

Collagen-based cell migration models in vitro and in vivo

(2009) Katarina Wolf et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Imaging of Effector Memory T Cells during a Delayed-Type Hypersensitivity Reaction and Suppression by Kv1.3 Channel Block

(2008) Melanie P. Matheu et al.   IMMUNITY

Macrophage and T Cell Dynamics during the Development and Disintegration of Mycobacterial Granulomas

(2008) Jackson G. Egen et al.   IMMUNITY

The microanatomy of T-cell responses

(2008) Tim Lämmermann et al.   IMMUNOLOGICAL REVIEWS

PI3K accelerates, but is not required for, neutrophil chemotaxis to fMLP

(2008) B. Heit et al.   JOURNAL OF CELL SCIENCE

A point mutation in the murineHem1gene reveals an essential role for Hematopoietic Protein 1 in lymphopoiesis and innate immunity

(2008) Heon Park et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Fibrillogenesis in Dense Collagen Solutions: A Physicochemical Study

(2008) F. Gobeaux et al.   JOURNAL OF MOLECULAR BIOLOGY

A platform for assessing chemotactic migration within a spatiotemporally defined 3D microenvironment

(2008) Vinay V. Abhyankar et al.   LAB ON A CHIP

Rapid leukocyte migration by integrin-independent flowing and squeezing

(2008) Tim Lämmermann et al.   NATURE

Amoeboid T lymphocytes require the septin cytoskeleton for cortical integrity and persistent motility

(2008) Aaron J. Tooley et al.   NATURE CELL BIOLOGY

Interstitial leukocyte migration and immune function

(2008) Peter Friedl et al.   NATURE IMMUNOLOGY

The actin regulator coronin 1A is mutant in a thymic egress–deficient mouse strain and in a patient with severe combined immunodeficiency

(2008) Lawrence R Shiow et al.   NATURE IMMUNOLOGY

Regulation of Dendritic Cell Migration by CD74, the MHC Class II-Associated Invariant Chain

(2008) G. Faure-Andre et al.   SCIENCE

Migratory Dermal Dendritic Cells Act as Rapid Sensors of Protozoan Parasites

(2008) Lai Guan Ng et al.   PLoS Pathogens

Image Correlation Spectroscopy of Multiphoton Images Correlates with Collagen Mechanical Properties

(2007) Christopher B. Raub et al.   BIOPHYSICAL JOURNAL