Chromatin replication and epigenome maintenance

The role of the DNA sliding clamp in Okazaki fragment maturation in archaea and eukaryotes

(2011) Thomas R. Beattie et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Replication-Coupled Chromatin Assembly Generates a Neuronal Bilateral Asymmetry in C. elegans

(2011) Shunji Nakano et al.   CELL

Selective Bypass of a Lagging Strand Roadblock by the Eukaryotic Replicative DNA Helicase

(2011) Yu V. Fu et al.   CELL

Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development

(2011) Assaf C. Bester et al.   CELL

S. pombereplication protein Cdc18 (Cdc6) interacts with Swi6 (HP1) heterochromatin protein

(2011) Pao-Chen Li et al.   CELL CYCLE

Locking the genome: nuclear organization and cell fate

(2011) Peter Meister et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Progressive methylation of ageing histones by Dot1 functions as a timer

(2011) Dirk De Vos et al.   EMBO REPORTS

A model for mitotic inheritance of histone lysine methylation

(2011) Mo Xu et al.   EMBO REPORTS

Phosphorylation of H4 Ser 47 promotes HIRA-mediated nucleosome assembly

(2011) B. Kang et al.   GENES & DEVELOPMENT

Structure of a CENP-A-histone H4 heterodimer in complex with chaperone HJURP

(2011) H. Hu et al.   GENES & DEVELOPMENT

Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation

(2011) H. Wu et al.   GENES & DEVELOPMENT

Tight protein-DNA interactions favor gene silencing

(2011) M. Dubarry et al.   GENES & DEVELOPMENT

Analysis of protein dynamics at active, stalled, and collapsed replication forks

(2011) B. M. Sirbu et al.   GENES & DEVELOPMENT

Genome-scale analysis of metazoan replication origins reveals their organization in specific but flexible sites defined by conserved features

(2011) C. Cayrou et al.   GENOME RESEARCH

Histone Chaperone FACT Coordinates Nucleosome Interaction through Multiple Synergistic Binding Events

(2011) Duane D. Winkler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Histone Chaperone Facilitates Chromatin Transcription (FACT) Protein Maintains Normal Replication Fork Rates

(2011) Takuya Abe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sequential Establishment of Marks on Soluble Histones H3 and H4

(2011) Francisca Alvarez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload

(2011) Marjorie A. Kuipers et al.   JOURNAL OF CELL BIOLOGY

SET8 is degraded via PCNA-coupled CRL4(CDT2) ubiquitylation in S phase and after UV irradiation

(2011) Stine Jørgensen et al.   JOURNAL OF CELL BIOLOGY

Dynamics of Histone H3 Deposition In Vivo Reveal a Nucleosome Gap-Filling Mechanism for H3.3 to Maintain Chromatin Integrity

(2011) Dominique Ray-Gallet et al.   MOLECULAR CELL

Maintenance of Silent Chromatin through Replication Requires SWI/SNF-like Chromatin Remodeler SMARCAD1

(2011) Samuel P. Rowbotham et al.   MOLECULAR CELL

A Specific Function for the Histone Chaperone NASP to Fine-Tune a Reservoir of Soluble H3-H4 in the Histone Supply Chain

(2011) Adam J.L. Cook et al.   MOLECULAR CELL

RNAi promotes heterochromatic silencing through replication-coupled release of RNA Pol II

(2011) Mikel Zaratiegui et al.   NATURE

Coordination of DNA replication and histone modification by the Rik1–Dos2 complex

(2011) Fei Li et al.   NATURE

Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site

(2011) Anne Letessier et al.   NATURE

DNA replication timing and long-range DNA interactions predict mutational landscapes of cancer genomes

(2011) Subhajyoti De et al.   NATURE BIOTECHNOLOGY

Cohesin: a catenase with separate entry and exit gates?

(2011) Kim Nasmyth   NATURE CELL BIOLOGY

Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer

(2011) Raffaella Di Micco et al.   NATURE CELL BIOLOGY

Increased methylation variation in epigenetic domains across cancer types

(2011) Kasper Daniel Hansen et al.   NATURE GENETICS

The structural basis for MCM2–7 helicase activation by GINS and Cdc45

(2011) Alessandro Costa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role for hACF1 in the G2/M damage checkpoint

(2011) Sara Sánchez-Molina et al.   NUCLEIC ACIDS RESEARCH

How dormant origins promote complete genome replication

(2011) J. Julian Blow et al.   TRENDS IN BIOCHEMICAL SCIENCES

Heterochromatin establishment in the context of genome-wide epigenetic reprogramming

(2011) Aline V. Probst et al.   TRENDS IN GENETICS

Proliferating cell nuclear antigen is required for loading of the SMCX/KMD5C histone demethylase onto chromatin

(2011) Zhihui Liang et al.   Epigenetics & Chromatin

DNA mediated chromatin pull-down for the study of chromatin replication

(2011) Anna E. Kliszczak et al.   Scientific Reports

Patterns and Mechanisms of Ancestral Histone Protein Inheritance in Budding Yeast

(2011) Marta Radman-Livaja et al.   PLOS BIOLOGY

PcG Complexes Set the Stage for Epigenetic Inheritance of Gene Silencing in Early S Phase before Replication

(2011) Chiara Lanzuolo et al.   PLoS Genetics

Replication stress, a source of epigenetic aberrations in cancer?

(2010) Zuzana Jasencakova et al.   BIOESSAYS

Hdac3 Is Essential for the Maintenance of Chromatin Structure and Genome Stability

(2010) Srividya Bhaskara et al.   CANCER CELL

Inhibition of Histone Deacetylase in Cancer Cells Slows Down Replication Forks, Activates Dormant Origins, and Induces DNA Damage

(2010) Chiara Conti et al.   CANCER RESEARCH

Systematic Protein Location Mapping Reveals Five Principal Chromatin Types in Drosophila Cells

(2010) Guillaume J. Filion et al.   CELL

Clusters, factories and domains

(2010) Peter J. Gillespie et al.   CELL CYCLE

The Rtt109 histone acetyltransferase facilitates error-free replication to prevent CAG/CTG repeat contractions

(2010) Jiahui H. Yang et al.   DNA REPAIR

RNAi-based screening identifies the Mms22L–Nfkbil2 complex as a novel regulator of DNA replication in human cells

(2010) Wojciech Piwko et al.   EMBO JOURNAL

Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns

(2010) Alessia Errico et al.   EMBO REPORTS

Cohesin organizes chromatin loops at DNA replication factories

(2010) E. Guillou et al.   GENES & DEVELOPMENT

Heterochromatin protein 1 (HP1) modulates replication timing of the Drosophila genome

(2010) M. Schwaiger et al.   GENOME RESEARCH

Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types

(2010) T. Ryba et al.   GENOME RESEARCH

Kinetics of Re-establishing H3K79 Methylation Marks in Global Human Chromatin

(2010) Steve M. M. Sweet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Replication factory activation can be decoupled from the replication timing program by modulating Cdk levels

(2010) Alexander M. Thomson et al.   JOURNAL OF CELL BIOLOGY

Cyclin A Promotes S-Phase Entry via Interaction with the Replication Licensing Factor Mcm7

(2010) T. Chibazakura et al.   MOLECULAR AND CELLULAR BIOLOGY

Epigenetic Instability due to Defective Replication of Structured DNA

(2010) Peter Sarkies et al.   MOLECULAR CELL

The MMS22L-TONSL Complex Mediates Recovery from Replication Stress and Homologous Recombination

(2010) Lara O'Donnell et al.   MOLECULAR CELL

Identification of the MMS22L-TONSL Complex that Promotes Homologous Recombination

(2010) Eris Duro et al.   MOLECULAR CELL

Replication Stress Interferes with Histone Recycling and Predeposition Marking of New Histones

(2010) Zuzana Jasencakova et al.   MOLECULAR CELL

HBO1 Histone Acetylase Activity Is Essential for DNA Replication Licensing and Inhibited by Geminin

(2010) Benoit Miotto et al.   MOLECULAR CELL

A WD-Repeat Protein Stabilizes ORC Binding to Chromatin

(2010) Zhen Shen et al.   MOLECULAR CELL

A Genome-wide Camptothecin Sensitivity Screen Identifies a Mammalian MMS22L-NFKBIL2 Complex Required for Genomic Stability

(2010) Brenda C. O'Connell et al.   MOLECULAR CELL

A Role for Gcn5 in Replication-Coupled Nucleosome Assembly

(2010) Rebecca J. Burgess et al.   MOLECULAR CELL

The Histone Chaperone Nap1 Promotes Nucleosome Assembly by Eliminating Nonnucleosomal Histone DNA Interactions

(2010) Andrew J. Andrews et al.   MOLECULAR CELL

Elevated Histone Expression Promotes Life Span Extension

(2010) Jason Feser et al.   MOLECULAR CELL

CRL4Cdt2-Mediated Destruction of the Histone Methyltransferase Set8 Prevents Premature Chromatin Compaction in S Phase

(2010) Richard C. Centore et al.   MOLECULAR CELL

CENP-B preserves genome integrity at replication forks paused by retrotransposon LTR

(2010) Mikel Zaratiegui et al.   NATURE

Regulation of heterochromatic DNA replication by histone H3 lysine 27 methyltransferases

(2010) Yannick Jacob et al.   NATURE

Ubiquitin-dependent DNA damage bypass is separable from genome replication

(2010) Yasukazu Daigaku et al.   NATURE

The histone H4 Lys 20 methyltransferase PR-Set7 regulates replication origins in mammalian cells

(2010) Mathieu Tardat et al.   NATURE CELL BIOLOGY

Chromatin structure and the inheritance of epigenetic information

(2010) Raphaël Margueron et al.   NATURE REVIEWS GENETICS

Eukaryotic DNA replication origins: many choices for appropriate answers

(2010) Marcel Méchali   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Maintaining genome stability at the replication fork

(2010) Dana Branzei et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Accessibility of the Drosophila genome discriminates PcG repression, H4K16 acetylation and replication timing

(2010) Oliver Bell et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The program for processing newly synthesized histones H3.1 and H4

(2010) Eric I Campos et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres

(2010) Roderick J O'Sullivan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Pre-replication complex proteins assemble at regions of low nucleosome occupancy within the Chinese hamster dihydrofolate reductase initiation zone

(2010) Yoav Lubelsky et al.   NUCLEIC ACIDS RESEARCH

Human origin recognition complex is essential for HP1 binding to chromatin and heterochromatin organization

(2010) S. G. Prasanth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Partitioning of Histone H3-H4 Tetramers During DNA Replication-Dependent Chromatin Assembly

(2010) M. Xu et al.   SCIENCE

Replicating chromatin: a tale of histonesThis paper is one of a selection of papers published in this Special Issue, entitled CSBMCB’s 51st Annual Meeting – Epigenetics and Chromatin Dynamics, and has undergone the Journal’s usual peer review process.

(2009) Anja Groth   Biochemistry and Cell Biology

Epigenetics in cancer

(2009) S. Sharma et al.   CARCINOGENESIS

Polycomb Proteins Remain Bound to Chromatin and DNA during DNA Replication In Vitro

(2009) Nicole J. Francis et al.   CELL

Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing

(2009) Dirk Remus et al.   CELL

Eukaryotic DNA replication control: Lock and load, then fire

(2009) Dirk Remus et al.   CURRENT OPINION IN CELL BIOLOGY

Chromatin assembly controls replication fork stability

(2009) Marta Clemente-Ruiz et al.   EMBO REPORTS

The HP1α–CAF1–SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin

(2009) Alejandra Loyola et al.   EMBO REPORTS

Chromatin state marks cell-type- and gender-specific replication of the Drosophila genome

(2009) M. Schwaiger et al.   GENES & DEVELOPMENT

Drosophila ORC localizes to open chromatin and marks sites of cohesin complex loading

(2009) H. K. MacAlpine et al.   GENOME RESEARCH

Acetylation of Dna2 Endonuclease/Helicase and Flap Endonuclease 1 by p300 Promotes DNA Stability by Creating Long Flap Intermediates

(2009) Lata Balakrishnan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mcm Complex: Unwinding the Mechanism of a Replicative Helicase

(2009) M. L. Bochman et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Shifts in Replication Timing Actively Affect Histone Acetylation during Nucleosome Reassembly

(2009) Laura Lande-Diner et al.   MOLECULAR CELL

CBP/p300-mediated acetylation of histone H3 on lysine 56

(2009) Chandrima Das et al.   NATURE

Cohesin acetylation speeds the replication fork

(2009) Marie-Emilie Terret et al.   NATURE

Role of the polycomb protein EED in the propagation of repressive histone marks

(2009) Raphael Margueron et al.   NATURE

Large histone H3 lysine 9 dimethylated chromatin blocks distinguish differentiated from embryonic stem cells

(2009) Bo Wen et al.   NATURE GENETICS

Rethinking how DNA methylation patterns are maintained

(2009) Peter A. Jones et al.   NATURE REVIEWS GENETICS

Epigenetic inheritance during the cell cycle

(2009) Aline V. Probst et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Involvement of a chromatin remodeling complex in damage tolerance during DNA replication

(2009) Karina B Falbo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Establishment of Histone Modifications after Chromatin Assembly

(2009) Annette N. D. Scharf et al.   NUCLEIC ACIDS RESEARCH

Cyclin A-Cdk1 regulates the origin firing program in mammalian cells

(2009) Y. Katsuno et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequencing newly replicated DNA reveals widespread plasticity in human replication timing

(2009) R. S. Hansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

(2009) E. Lieberman-Aiden et al.   SCIENCE

Acetylation of Histone H3 Lysine 56 Regulates Replication-Coupled Nucleosome Assembly

(2008) Qing Li et al.   CELL

Ino80 Chromatin Remodeling Complex Promotes Recovery of Stalled Replication Forks

(2008) Kenji Shimada et al.   CURRENT BIOLOGY

RNA Interference Guides Histone Modification during the S Phase of Chromosomal Replication

(2008) Anna Kloc et al.   CURRENT BIOLOGY

HBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1

(2008) B. Miotto et al.   GENES & DEVELOPMENT

Linker Histone Phosphorylation Regulates Global Timing of Replication Origin Firing

(2008) Christophe Thiriet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Interaction between SET8 and Proliferating Cell Nuclear Antigen Couples H4-K20 Methylation with DNA Replication

(2008) Michael S. Y. Huen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The highly conserved nuclear lamin Ig-fold binds to PCNA: its role in DNA replication

(2008) Dale K. Shumaker et al.   JOURNAL OF CELL BIOLOGY

Replication fork movement sets chromatin loop size and origin choice in mammalian cells

(2008) Sylvain Courbet et al.   NATURE

Cell cycle control of centromeric repeat transcription and heterochromatin assembly

(2008) Ee Sin Chen et al.   NATURE

A model for transmission of the H3K27me3 epigenetic mark

(2008) Klaus H. Hansen et al.   NATURE CELL BIOLOGY

Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail

(2008) William F. Marzluff et al.   NATURE REVIEWS GENETICS

The HP1–p150/CAF-1 interaction is required for pericentric heterochromatin replication and S-phase progression in mouse cells

(2008) Jean-Pierre Quivy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Ino80 chromatin-remodeling enzyme regulates replisome function and stability

(2008) Manolis Papamichos-Chronakis et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Excess MCM proteins protect human cells from replicative stress by licensing backup origins of replication

(2008) Arkaitz Ibarra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interaction between HMGA1a and the origin recognition complex creates site-specific replication origins

(2008) A. W. Thomae et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Oncogene-Induced DNA Damage Model for Cancer Development

(2008) T. D. Halazonetis et al.   SCIENCE

Global Reorganization of Replication Domains During Embryonic Stem Cell Differentiation

(2008) Ichiro Hiratani et al.   PLOS BIOLOGY

Mutations in deoxyribonucleotide biosynthesis pathway cause spreading of silencing across heterochromatic barriers at the mating-type region of the fission yeast

(2007) Gurjeet Singh et al.   YEAST