IL-1R/TLR2 through MyD88 Divergently Modulates Osteoclastogenesis through Regulation of Nuclear Factor of Activated T Cells c1 (NFATc1) and B Lymphocyte-induced Maturation Protein-1 (Blimp1)

Toll/interleukin-1 receptor (TIR) domain-mediated cellular signaling pathways

(2015) Kannan Badri Narayanan et al.   APOPTOSIS

Porphyromonas gingivalis Lipopolysaccharide Weakly Activates M1 and M2 Polarized Mouse Macrophages but Induces Inflammatory Cytokines

(2014) James A. Holden et al.   INFECTION AND IMMUNITY

Relevance of the Myeloid Differentiation Factor 88 (MyD88) on RANKL, OPG, and Nod Expressions Induced by TLR and IL-1R Signaling in Bone Marrow Stromal Cells

(2014) Fábio Renato Manzolli Leite et al.   INFLAMMATION

RBP-J imposes a requirement for ITAM-mediated costimulation of osteoclastogenesis

(2014) Susan Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Distinct Lipid A Moieties Contribute to Pathogen-Induced Site-Specific Vascular Inflammation

(2014) Connie Slocum et al.   PLoS Pathogens

Porphyromonas gingivalis LPS inhibits osteoblastic differentiation and promotes pro-inflammatory cytokine production in human periodontal ligament stem cells

(2013) Hirohito Kato et al.   ARCHIVES OF ORAL BIOLOGY

Mutational Analysis Identifies Residues Crucial for Homodimerization of Myeloid Differentiation Factor 88 (MyD88) and for Its Function in Immune Cells

(2013) Maria Loiarro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Basis of Requirement of Receptor Activator of Nuclear Factor κB Signaling for Interleukin 1-mediated Osteoclastogenesis

(2012) Joel Jules et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Porphyromonas gingivalis-derived lipopolysaccharide-mediated activation of MAPK signaling regulates inflammatory response and differentiation in human periodontal ligament fibroblasts

(2012) Taegun Seo et al.   JOURNAL OF MICROBIOLOGY

Feedback inhibition of osteoclastogenesis during inflammation by IL-10, M-CSF receptor shedding, and induction of IRF8

(2011) Lionel B. Ivashkiv et al.   Annals of the New York Academy of Sciences

TLR2-dependent Modulation of Osteoclastogenesis byPorphyromonas gingivalisthrough Differential Induction of NFATc1 and NF-κB

(2011) Ping Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Akt Induces Osteoclast Differentiation through Regulating the GSK3 /NFATc1 Signaling Cascade

(2011) J. B. Moon et al.   JOURNAL OF IMMUNOLOGY

Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors

(2011) Baohong Zhao et al.   ARTHRITIS RESEARCH & THERAPY

Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis

(2011) Tobias Braun et al.   ARTHRITIS RESEARCH & THERAPY

IL-1 plays an important role in the bone metabolism under physiological conditions

(2010) Y.-M. Lee et al.   INTERNATIONAL IMMUNOLOGY

The Blimp1–Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis

(2010) Yoshiteru Miyauchi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Blimp1-mediated repression of negative regulators is required for osteoclast differentiation

(2010) K. Nishikawa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress

(2009) Luke A. J. O'Neill   IMMUNOLOGICAL REVIEWS

Molecular Mechanism of the Bifunctional Role of Lipopolysaccharide in Osteoclastogenesis

(2009) Jianzhong Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IL-10 Suppresses Calcium-Mediated Costimulation of Receptor Activator NF- B Signaling during Human Osteoclast Differentiation by Inhibiting TREM-2 Expression

(2009) K.-H. Park-Min et al.   JOURNAL OF IMMUNOLOGY

Inhibition of RANK Expression and Osteoclastogenesis by TLRs and IFN-  in Human Osteoclast Precursors

(2009) J.-D. Ji et al.   JOURNAL OF IMMUNOLOGY

Impaired osteoclastogenesis by staphylococcal lipoteichoic acid through Toll-like receptor 2 with partial involvement of MyD88

(2009) Jihyun Yang et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Interferon regulatory factor-8 regulates bone metabolism by suppressing osteoclastogenesis

(2009) Baohong Zhao et al.   NATURE MEDICINE

The role of Toll-like receptors in rheumatoid arthritis

(2009) Qi-Quan Huang et al.   Current Rheumatology Reports

Calcium Imaging of Cortical Neurons using Fura-2 AM

(2009) Odmara L Barreto-Chang et al.   Jove-Journal of Visualized Experiments

Regulation and Functions of Blimp-1 in T and B Lymphocytes

(2008) Gislâine Martins et al.   Annual Review of Immunology

Induction of osteoclast-associated receptor, a key osteoclast costimulation molecule, in rheumatoid arthritis

(2008) Sonja Herman et al.   ARTHRITIS AND RHEUMATISM

Taking a Toll on the bones: Regulation of bone metabolism by innate immune regulators

(2008) Zvi Bar-Shavit   AUTOIMMUNITY

TLR-4, IL-1R and TNF-R signaling to NF-κB: variations on a common theme

(2008) L. Verstrepen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Osteoimmunology: Interactions of the Bone and Immune System

(2008) Joseph Lorenzo et al.   ENDOCRINE REVIEWS

Lipopolysaccharide (LPS) of Porphyromonas gingivalis induces IL-1β, TNF-α and IL-6 production by THP-1 cells in a way different from that of Escherichia coli LPS

(2008) Diya Zhang et al.   Innate Immunity

Inflammation and Bone Loss in Periodontal Disease

(2008) David L. Cochran   JOURNAL OF PERIODONTOLOGY