Adaptation of iron requirement to hypoxic conditions at high altitude

Increased gastrin gene expression provides a physiological advantage to mice under hypoxic conditions

(2015) Marie Laval et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Erythropoietin's inhibiting impact on hepcidin expression occurs indirectly

(2015) Elena Gammella et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Iron, oxygen, and the pulmonary circulation

(2015) Matthew C. Frise et al.   JOURNAL OF APPLIED PHYSIOLOGY

Increased hepcidin levels in high-altitude pulmonary edema

(2015) Sandro Altamura et al.   JOURNAL OF APPLIED PHYSIOLOGY

Recent Advances in Iron Metabolism

(2015) PAOLO BURATTI et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Downregulation of duodenal SLC transporters and activation of proinflammatory signaling constitute the early response to high altitude in humans

(2014) Kacper A. Wojtal et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Crossroads of Iron with Hypoxia and Cellular Metabolism. Implications in the Pathobiology of Pulmonary Hypertension

(2014) Jeffrey C. Robinson et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Circulating factors are involved in hypoxia-induced hepcidin suppression

(2014) Giulia Ravasi et al.   BLOOD CELLS MOLECULES AND DISEASES

Novel antibodies directed against the human erythropoietin receptor: creating a basis for clinical implementation

(2014) Perry Maxwell et al.   BRITISH JOURNAL OF HAEMATOLOGY

Hypoxia-Inducible Factors Link Iron Homeostasis and Erythropoiesis

(2014) Yatrik M. Shah et al.   GASTROENTEROLOGY

Hypoxia induced downregulation of hepcidin is mediated by platelet derived growth factor BB

(2014) Thomas Sonnweber et al.   GUT

Investigating the real role of HIF-1 and HIF-2 in iron recycling by macrophages

(2014) J. R. R. Mathieu et al.   HAEMATOLOGICA

Identification of erythroferrone as an erythroid regulator of iron metabolism

(2014) Léon Kautz et al.   NATURE GENETICS

Effect of obesity and exercise on the expression of the novel myokines, Myonectin and Fibronectin type III domain containing 5

(2014) Jonathan M. Peterson et al.   PeerJ

Erythrocytosis: the HIF pathway in control

(2013) K. Franke et al.   BLOOD

The IRP1-HIF-2α Axis Coordinates Iron and Oxygen Sensing with Erythropoiesis and Iron Absorption

(2013) Sheila A. Anderson et al.   Cell Metabolism

Deletion of Iron Regulatory Protein 1 Causes Polycythemia and Pulmonary Hypertension in Mice through Translational Derepression of HIF2α

(2013) Manik C. Ghosh et al.   Cell Metabolism

Targeting the HIF pathway in inflammation and immunity

(2013) Carsten C Scholz et al.   CURRENT OPINION IN PHARMACOLOGY

Adaptation of iron transport and metabolism to acute high-altitude hypoxia in mountaineers

(2013) Oliver Goetze et al.   HEPATOLOGY

High altitude journeys and flights are associated with an increased risk of flares in inflammatory bowel disease patients

(2013) Stephan R. Vavricka et al.   Journal of Crohns & Colitis

Oxygen sensing and hypoxia signalling pathways in animals: the implications of physiology for cancer

(2013) Peter J. Ratcliffe   JOURNAL OF PHYSIOLOGY-LONDON

Out of Balance—Systemic Iron Homeostasis in Iron-Related Disorders

(2013) Andrea Steinbicker et al.   Nutrients

Pulmonary Artery Pressure Increases During Commercial Air Travel in Healthy Passengers

(2012) Thomas G. Smith et al.   AVIATION SPACE AND ENVIRONMENTAL MEDICINE

Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis

(2012) A. Laitala et al.   BLOOD

Disturbed eating at high altitude: influence of food preferences, acute mountain sickness and satiation hormones

(2012) Isabelle Aeberli et al.   EUROPEAN JOURNAL OF NUTRITION

The murine growth differentiation factor 15 is not essential for systemic iron homeostasis in phlebotomized mice

(2012) G. Casanovas et al.   HAEMATOLOGICA

Myonectin (CTRP15), a Novel Myokine That Links Skeletal Muscle to Systemic Lipid Homeostasis

(2012) Marcus M. Seldin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesis

(2012) Qingdu Liu et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of hepcidin expression at high altitude

(2011) N. P. Talbot et al.   BLOOD

Deletion of HIF-2  in the enterocytes decreases the severity of tissue iron loading in hepcidin knockout mice

(2011) M. Mastrogiannaki et al.   BLOOD

Hypoxia: Adapting to High Altitude by Mutating EPAS-1, the Gene Encoding HIF-2α

(2011) Martha C. Tissot van Patot et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Effects of Aerobic Exercise Training on C1q Tumor Necrosis Factor α-Related Protein Isoform 5 (Myonectin): Association with Insulin Resistance and Mitochondrial DNA Density in Women

(2011) Soo Lim et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project

(2010) A. Piperno et al.   BLOOD

Two to Tango: Regulation of Mammalian Iron Metabolism

(2010) Matthias W. Hentze et al.   CELL

Regulation of iron pathways in response to hypoxia

(2010) Nikolai L. Chepelev et al.   FREE RADICAL BIOLOGY AND MEDICINE

T1080 Unsedated Transnasal Esophago-Gastroduodenoscopy at 4559 M (14957 Ft) -Endoscopic Findings in Healthy Mountaineers After Rapid Ascent to High Altitude

(2010) Heiko Fruehauf et al.   GASTROENTEROLOGY

Erythropoietin: not just about erythropoiesis

(2010) Pietro Ghezzi et al.   LANCET

The Neuronal Control of Hypoxic Ventilation

(2009) Max Gassmann et al.   Annals of the New York Academy of Sciences

Intestinal Hypoxia-Inducible Transcription Factors Are Essential for Iron Absorption following Iron Deficiency

(2009) Yatrik M. Shah et al.   Cell Metabolism

Cumulative effects of consecutive running sessions on hemolysis, inflammation and hepcidin activity

(2009) Peter Peeling et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin

(2009) D. R. Ashby et al.   HAEMATOLOGICA

Effects of Iron Supplementation and Depletion on Hypoxic Pulmonary Hypertension

(2009) Thomas G. Smith et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Training Surface and Intensity

(2009) PETER PEELING et al.   MEDICINE AND SCIENCE IN SPORTS AND EXERCISE

Ventilatory responses to acute and chronic hypoxia are altered in female but not male Paskin-deficient mice

(2008) Jorge Soliz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Systemic Iron Homeostasis and the Iron-Responsive Element/Iron-Regulatory Protein (IRE/IRP) Regulatory Network

(2008) Martina U. Muckenthaler et al.   Annual Review of Nutrition

Athletic induced iron deficiency: new insights into the role of inflammation, cytokines and hormones

(2008) Peter Peeling et al.   EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY

2-Oxoglutarate-dependent oxygenases control hepcidin gene expression

(2008) Georgia G. Braliou et al.   JOURNAL OF HEPATOLOGY

The increase in pulmonary arterial pressure caused by hypoxia depends on iron status

(2008) Thomas G. Smith et al.   JOURNAL OF PHYSIOLOGY-LONDON