A Potential Target of Tanshinone IIA for Acute Promyelocytic Leukemia Revealed by Inverse Docking and Drug Repurposing

Identification of a Potential Anticancer Target of Danshensu by Inverse Docking

(2014) Shao-Jun Chen et al.   Asian Pacific Journal of Cancer Prevention

Comparative Reverse Screening Approach to Identify Potential Anti-neoplastic Targets of Saffron Functional Components and Binding Mode

(2013) Biplab Bhattacharjee et al.   Asian Pacific Journal of Cancer Prevention

Tanshinone II-A Inhibits Angiogenesis through Down Regulation of COX-2 in Human Colorectal Cancer

(2013) Li-Hong Zhou et al.   Asian Pacific Journal of Cancer Prevention

Identification of Proapoptopic, Anti-Inflammatory, Anti-Proliferative, Anti-Invasive and Anti-Angiogenic Targets of Essential Oils in Cardamom by Dual Reverse Virtual Screening and Binding Pose Analysis

(2013) Biplab Bhattacharjee et al.   Asian Pacific Journal of Cancer Prevention

Computational Drug Repositioning: From Data to Therapeutics

(2013) M R Hurle et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Tanshinone IIA inhibits breast cancer stem cells growth in vitro and in vivo through attenuation of IL-6/STAT3/NF-kB signaling pathways

(2013) Caiyu Lin et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Proteomic analysis reveals tanshinone IIA enhances apoptosis of advanced cervix carcinoma CaSki cells through mitochondria intrinsic and endoplasmic reticulum stress pathways

(2013) Tai-Long Pan et al.   PROTEOMICS

Tanshinone II-A: new perspectives for old remedies

(2012) Suowen Xu et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

A System-Level Investigation into the Mechanisms of Chinese Traditional Medicine: Compound Danshen Formula for Cardiovascular Disease Treatment

(2012) Xiuxiu Li et al.   PLoS One

Cardiovascular actions and therapeutic potential of tanshinone IIA

(2011) Si Gao et al.   ATHEROSCLEROSIS

Computational tools for polypharmacology and repurposing

(2011) Janosch Achenbach et al.   Future Medicinal Chemistry

Biosynthesis, total syntheses, and antitumor activity of tanshinones and their analogs as potential therapeutic agents

(2011) Yizhou Dong et al.   NATURAL PRODUCT REPORTS

DRAR-CPI: a server for identifying drug repositioning potential and adverse drug reactions via the chemical–protein interactome

(2011) Heng Luo et al.   NUCLEIC ACIDS RESEARCH

Chemical-protein interactome and its application in off-target identification

(2011) Lun Yang et al.   Interdisciplinary Sciences-Computational Life Sciences

PharmMapper server: a web server for potential drug target identification using pharmacophore mapping approach

(2010) Xiaofeng Liu et al.   NUCLEIC ACIDS RESEARCH

Identifying Unexpected Therapeutic Targets via Chemical-Protein Interactome

(2010) Lun Yang et al.   PLoS One

Inhibitory effects of tanshinone II-A on invasion and metastasis of human colon carcinoma cells

(2009) Yun-feng Shan et al.   ACTA PHARMACOLOGICA SINICA

SePreSA: a server for the prediction of populations susceptible to serious adverse drug reactions implementing the methodology of a chemical–protein interactome

(2009) Lun Yang et al.   NUCLEIC ACIDS RESEARCH

Hidden abnormalities and novel classification of t(15;17) acute promyelocytic leukemia (APL) based on genomic alterations

(2008) T. Akagi et al.   BLOOD

Dissection of mechanisms of Chinese medicinal formula Realgar-Indigo naturalis as an effective treatment for promyelocytic leukemia

(2008) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA