Impact of the CTLA-4/CD28 axis on the processes of joint inflammation in rheumatoid arthritis

Pathogen-induced human TH17 cells produce IFN-γ or IL-10 and are regulated by IL-1β

(2012) Christina E. Zielinski et al.   NATURE

Regulation and Functions of the IL-10 Family of Cytokines in Inflammation and Disease

(2011) Wenjun Ouyang et al.   Annual Review of Immunology

Blockade of CTLA-4 Decreases the Generation of Multifunctional Memory CD4+ T Cells In Vivo

(2011) M. Rudolph et al.   JOURNAL OF IMMUNOLOGY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Trans-Endocytosis of CD80 and CD86: A Molecular Basis for the Cell-Extrinsic Function of CTLA-4

(2011) O. S. Qureshi et al.   SCIENCE

Association of the CD28/CTLA4/ICOS polymorphisms with susceptibility to rheumatoid arthritis

(2010) Young Ock Kim et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

CTLA-4 (CD152) inhibits T cell function by activating the ubiquitin ligase Itch

(2010) Holger Hoff et al.   MOLECULAR IMMUNOLOGY

CTLA-4 (CD152) controls homeostasis and suppressive capacity of regulatory T cells in mice

(2009) Paula Kolar et al.   ARTHRITIS AND RHEUMATISM

Surface CD152 (CTLA-4) Expression and Signaling Dictates Longevity of CD28null T Cells

(2009) H. Hoff et al.   JOURNAL OF IMMUNOLOGY

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

(2009) Soumya Raychaudhuri et al.   NATURE GENETICS

Mode of action of abatacept in rheumatoid arthritis patients having failed tumour necrosis factor blockade: a histological, gene expression and dynamic magnetic resonance imaging pilot study

(2008) M H Buch et al.   ANNALS OF THE RHEUMATIC DISEASES