Proposal of an in silico profiler for categorisation of repeat dose toxicity data of hair dyes

Adverse outcome pathways: hype or hope?

(2013) Mathieu Vinken et al.   ARCHIVES OF TOXICOLOGY

Hepatotoxicity: A scheme for generating chemical categories for read-across, structural alerts and insights into mechanism(s) of action

(2013) M. Hewitt et al.   CRITICAL REVIEWS IN TOXICOLOGY

Transition between Acute and Chronic Hepatotoxicity in Mice Is Associated with Impaired Energy Metabolism and Induction of Mitochondrial Heme Oxygenase-1

(2013) Aniket Nikam et al.   PLoS One

The definition of the toxicologically relevant applicability domain for the SNAr reaction for substituted pyridines and pyrimidines

(2013) S.J. Enoch et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Experimental verification, and domain definition, of structural alerts for protein binding: epoxides, lactones, nitroso, nitros, aldehydes and ketones

(2013) M.D. Nelms et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Experimental verification of structural alerts for the protein binding of cyclic compounds acting as Michael acceptors

(2013) N. Rodriguez-Sanchez et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Hazard Evaluation Support System (HESS) for predicting repeated dose toxicity using toxicological categories

(2013) Y. Sakuratani et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

The adverse outcome pathway concept: A pragmatic tool in toxicology

(2013) Mathieu Vinken   TOXICOLOGY

The role of chemistry in developing understanding of adverse outcome pathways and their application in risk assessment

(2013) Steve Gutsell et al.   Toxicology Research

Development of Mechanism-Based Structural Alerts for Respiratory Sensitization Hazard Identification

(2012) S. J. Enoch et al.   CHEMICAL RESEARCH IN TOXICOLOGY

The definition of the applicability domain relevant to skin sensitization for the aromatic nucleophilic substitution mechanism

(2012) S.J. Enoch et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Categorization of nitrobenzenes for repeated dose toxicity based on adverse outcome pathways

(2012) Y. Sakuratani et al.   SAR AND QSAR IN ENVIRONMENTAL RESEARCH

Prediction of Liver Injury Induced by Chemicals in Human With a Multiparametric Assay on Isolated Mouse Liver Mitochondria

(2012) Mathieu Porceddu et al.   TOXICOLOGICAL SCIENCES

The Development of Structure-Activity Relationships for Mitochondrial Dysfunction: Uncoupling of Oxidative Phosphorylation

(2012) Russell T. Naven et al.   TOXICOLOGICAL SCIENCES

A review of the electrophilic reaction chemistry involved in covalent protein binding relevant to toxicity

(2011) S. J. Enoch et al.   CRITICAL REVIEWS IN TOXICOLOGY

Central role of mitochondria in drug-induced liver injury

(2011) Dominique Pessayre et al.   DRUG METABOLISM REVIEWS

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Chemical Mechanisms for Skin Sensitization by Aromatic Compounds with Hydroxy and Amino Groups

(2009) Aynur O. Aptula et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Quantitative and Mechanistic Read Across for Predicting the Skin Sensitization Potential of Alkenes Acting via Michael Addition

(2008) Steven James Enoch et al.   CHEMICAL RESEARCH IN TOXICOLOGY