An overview of transcriptional regulation in response to toxicological insult

The Fundamental Role of the p53 Pathway in Tumor Metabolism and Its Implication in Tumor Therapy

(2012) L. Shen et al.   CLINICAL CANCER RESEARCH

In Vitro - In Vivo Correlation of Gene Expression Alterations Induced by Liver Carcinogens

(2012) T. Heise et al.   CURRENT MEDICINAL CHEMISTRY

Oxidant stress, mitochondria, and cell death mechanisms in drug-induced liver injury: Lessons learned from acetaminophen hepatotoxicity

(2012) Hartmut Jaeschke et al.   DRUG METABOLISM REVIEWS

Antioxidant-induced INrf2 (Keap1) tyrosine 85 phosphorylation controls the nuclear export and degradation of the INrf2–Cul3–Rbx1 complex to allow normal Nrf2 activation and repression

(2012) James W. Kaspar et al.   JOURNAL OF CELL SCIENCE

Abbott boosts investment in NRF2 activators for reducing oxidative stress

(2012) Sarah Crunkhorn   NATURE REVIEWS DRUG DISCOVERY

Genome-Wide Progesterone Receptor Binding: Cell Type-Specific and Shared Mechanisms in T47D Breast Cancer Cells and Primary Leiomyoma Cells

(2012) Ping Yin et al.   PLoS One

The p53 network: cellular and systemic DNA damage responses in aging and cancer

(2012) H. Christian Reinhardt et al.   TRENDS IN GENETICS

Gadd45 proteins: Relevance to aging, longevity and age-related pathologies

(2011) Alexey A. Moskalev et al.   AGEING RESEARCH REVIEWS

Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model

(2011) Paul Jennings et al.   ARCHIVES OF TOXICOLOGY

The cytoprotective role of the Keap1–Nrf2 pathway

(2011) Liam Baird et al.   ARCHIVES OF TOXICOLOGY

Novel insights into the regulation of antioxidant-response-elementmediated gene expression by electrophiles: induction of the transcriptional repressor BACH1 by Nrf2

(2011) Henna-Kaisa Jyrkkänen et al.   BIOCHEMICAL JOURNAL

Inflammation: a role for NR4A orphan nuclear receptors?

(2011) Jason P. McMorrow et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Modulation of RXR function through ligand design

(2011) Efrén Pérez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation

(2011) Tamas Varga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A review of the mammalian unfolded protein response

(2011) Anirikh Chakrabarti et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq

(2011) J. Schodel et al.   BLOOD

Liver X Receptors in Atherosclerosis and Inflammation

(2011) Seung-Soon Im et al.   CIRCULATION RESEARCH

Dioxin toxicity, aryl hydrocarbon receptor signaling, and apoptosis—Persistent pollutants affect programmed cell death

(2011) Martin Chopra et al.   CRITICAL REVIEWS IN TOXICOLOGY

Inhibiting signal transducer and activator of transcription 3: rationality and rationale design of inhibitors

(2011) Arun K Mankan et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Essential role for DNA-PK-mediated phosphorylation of NR4A nuclear orphan receptors in DNA double-strand break repair

(2011) M. Malewicz et al.   GENES & DEVELOPMENT

Activation of liver X receptor increases acetaminophen clearance and prevents its toxicity in mice

(2011) Simrat P.S. Saini et al.   HEPATOLOGY

Liver receptor homolog-1 is critical for adequate up-regulation of Cyp7a1 gene transcription and bile salt synthesis during bile salt sequestration

(2011) Carolien Out et al.   HEPATOLOGY

Non-canonical NF-κB signaling activation and regulation: principles and perspectives

(2011) Bahram Razani et al.   IMMUNOLOGICAL REVIEWS

Role of cAMP-responsive Element-binding Protein (CREB)-regulated Transcription Coactivator 3 (CRTC3) in the Initiation of Mitochondrial Biogenesis and Stress Response in Liver Cells

(2011) Tin Aung Than et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Orphan Receptor NR4A2 Modulates Fatty Acid Oxidation Pathways in Colorectal Cancer

(2011) Vijaykumar R. Holla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-widein SilicoIdentification of New Conserved and Functional Retinoic Acid Receptor Response Elements (Direct Repeats Separated by 5 bp)

(2011) Sébastien Lalevée et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Hypoxia-Inducible Factor-1  in Acetaminophen Hepatotoxicity

(2011) E. M. Sparkenbaugh et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Dual Regulation of the Transcriptional Activity of Nrf1 by  -TrCP- and Hrd1-Dependent Degradation Mechanisms

(2011) Y. Tsuchiya et al.   MOLECULAR AND CELLULAR BIOLOGY

Coordination of mitochondrial biogenesis by thyroid hormone

(2011) Joachim M. Weitzel et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The progesterone receptor regulates implantation, decidualization, and glandular development via a complex paracrine signaling network

(2011) Margeaux Wetendorf et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Tissue-specific function of farnesoid X receptor in liver and intestine

(2011) Yan Zhu et al.   PHARMACOLOGICAL RESEARCH

Comparative Gene Expression Profiles Induced by PPARγ and PPARα/γ Agonists in Human Hepatocytes

(2011) Alexandra Rogue et al.   PLoS One

Persistent organic pollutants have dose and CAG repeat length dependent effects on androgen receptor activity in vitro

(2011) Christel Björk et al.   REPRODUCTIVE TOXICOLOGY

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

(2011) M. H. Smith et al.   SCIENCE

The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation

(2011) P. Walter et al.   SCIENCE

Genomic Profiling Uncovers a Molecular Pattern for Toxicological Characterization of Mutagens and Promutagens In Vitro

(2011) Kathleen Boehme et al.   TOXICOLOGICAL SCIENCES

Exactly the Same but Different: Promiscuity and Diversity in the Molecular Mechanisms of Action of the Aryl Hydrocarbon (Dioxin) Receptor

(2011) Michael S. Denison et al.   TOXICOLOGICAL SCIENCES

Acetaminophen hepatotoxicity and HIF-1α induction in acetaminophen toxicity in mice occurs without hypoxia

(2011) Shubhra Chaudhuri et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

In vitro characterization of the immunotoxic potential of several perfluorinated compounds (PFCs)

(2011) Emanuela Corsini et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes

(2011) Alice Limonciel et al.   TOXICOLOGY IN VITRO

Short interfering RNA against STAT1 attenuates cisplatin-induced ototoxicity in the rat by suppressing inflammation

(2011) T Kaur et al.   Cell Death & Disease

Biomarkers of Immunotoxicity for Environmental and Public Health Research

(2011) Paurene Duramad et al.   International Journal of Environmental Research and Public Health

Systems Analysis of Protein Modification and Cellular Responses Induced by Electrophile Stress

(2010) Aaron T. Jacobs et al.   ACCOUNTS OF CHEMICAL RESEARCH

NR4A Orphan Nuclear Receptors

(2010) Yue Zhao et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Functional and physiological genomics of estrogen-related receptors (ERRs) in health and disease

(2010) Geneviève Deblois et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The molecular physiology of nuclear retinoic acid receptors. From health to disease

(2010) Vanessa Duong et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Liver X receptors as regulators of macrophage inflammatory and metabolic pathways

(2010) Noelia A-González et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Role of metallothionein in cadmium traffic and toxicity in kidneys and other mammalian organs

(2010) Ivan Sabolić et al.   BIOMETALS

HIF-1 prevents the overproduction of mitochondrial ROS after cytokine stimulation through induction of PDK-1

(2010) Keita Kirito et al.   CELL CYCLE

Crosstalk of reactive oxygen species and NF-κB signaling

(2010) Michael J Morgan et al.   CELL RESEARCH

Endocrine Disrupting Chemicals Targeting Estrogen Receptor Signaling: Identification and Mechanisms of Action

(2010) Erin K. Shanle et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Regulation of specific target genes and biological responses by estrogen receptor subtype agonists

(2010) Dale C Leitman et al.   CURRENT OPINION IN PHARMACOLOGY

HNF4α—role in drug metabolism and potential drug target?

(2010) Wendy W Hwang-Verslues et al.   CURRENT OPINION IN PHARMACOLOGY

Nuclear Orphan Receptor TAK1/TR4-Deficient Mice Are Protected Against Obesity-Linked Inflammation, Hepatic Steatosis, and Insulin Resistance

(2010) H. S. Kang et al.   DIABETES

Cytochrome P450 3A4 mRNA Is a More Reliable Marker than CYP3A4 Activity for Detecting Pregnane X Receptor-Activated Induction of Drug-Metabolizing Enzymes

(2010) O. A. Fahmi et al.   DRUG METABOLISM AND DISPOSITION

The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation

(2010) Jiangbin Ye et al.   EMBO JOURNAL

Nuclear receptor-mediated regulation of carboxylesterase expression and activity

(2010) Jeff L Staudinger et al.   Expert Opinion on Drug Metabolism & Toxicology

Regulation of the members of the mammalian heat shock factor family

(2010) Johanna K. Björk et al.   FEBS Journal

Hepatotoxicity of di-(2-ethylhexyl)phthalate is attributed to calcium aggravation, ROS-mediated mitochondrial depolarization, and ERK/NF-κB pathway activation

(2010) Jyotirmoy Ghosh et al.   FREE RADICAL BIOLOGY AND MEDICINE

STAT6 Transcription Factor Is a Facilitator of the Nuclear Receptor PPARγ-Regulated Gene Expression in Macrophages and Dendritic Cells

(2010) Attila Szanto et al.   IMMUNITY

Diminished Carcinogen Detoxification Is a Novel Mechanism for Hypoxia-inducible Factor 1-mediated Genetic Instability

(2010) Marten A. Schults et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Estrogen Signaling via Estrogen Receptor β

(2010) Chunyan Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interaction between Oxidative Stress Sensor Nrf2 and Xenobiotic-activated Aryl Hydrocarbon Receptor in the Regulation of the Human Phase II Detoxifying UDP-glucuronosyltransferase 1A10

(2010) Sandra Kalthoff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

(2010) Sonya G. Fonseca et al.   JOURNAL OF CLINICAL INVESTIGATION

Transcriptional Regulation of Renal Cytoprotective Genes by Nrf2 and Its Potential Use as a Therapeutic Target to Mitigate Cisplatin-Induced Nephrotoxicity

(2010) L. M. Aleksunes et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Evolution of promiscuous nuclear hormone receptors: LXR, FXR, VDR, PXR, and CAR

(2010) Matthew D. Krasowski et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Transcription Factor Nrf1 Mediates the Proteasome Recovery Pathway after Proteasome Inhibition in Mammalian Cells

(2010) Senthil K. Radhakrishnan et al.   MOLECULAR CELL

A Novel Bile Acid-Activated Vitamin D Receptor Signaling in Human Hepatocytes

(2010) Shuxin Han et al.   MOLECULAR ENDOCRINOLOGY

Aryl Hydrocarbon Receptor Is a Transcriptional Activator of the Human Breast Cancer Resistance Protein (BCRP/ABCG2)

(2010) K. P. Tan et al.   MOLECULAR PHARMACOLOGY

Multiple roles of the cell cycle inhibitor p21CDKN1A in the DNA damage response

(2010) Ornella Cazzalini et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Genome-Wide Analysis of Binding Sites and Direct Target Genes of the Orphan Nuclear Receptor NR2F1/COUP-TFI

(2010) Celina Montemayor et al.   PLoS One

Environmental toxicants and the developing immune system: A missing link in the global battle against infectious disease?

(2010) Bethany Winans et al.   REPRODUCTIVE TOXICOLOGY

ATM Activation by Oxidative Stress

(2010) Z. Guo et al.   SCIENCE

Cytochrome P4501A1 Is Required for Vascular Dysfunction and Hypertension Induced by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin

(2010) Phillip G. Kopf et al.   TOXICOLOGICAL SCIENCES

Increased Susceptibility of Nrf2-Null Mice to 1-Bromopropane–Induced Hepatotoxicity

(2010) Fang Liu et al.   TOXICOLOGICAL SCIENCES

Cadmium down-regulation of kidney Sp1 binding to mouse SGLT1 and SGLT2 gene promoters: Possible reaction of cadmium with the zinc finger domain of Sp1

(2010) Rajendra K. Kothinti et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

In vitro evaluation of the toxicity induced by nickel soluble and particulate forms in human airway epithelial cells

(2010) Efrat Forti et al.   TOXICOLOGY IN VITRO

Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity

(2010) Anja Wilmes et al.   TOXICOLOGY IN VITRO

Gene expression profiling of murine hepatic steatosis induced by tamoxifen

(2010) Min-Ho Lee et al.   TOXICOLOGY LETTERS

Mitochondria, reactive oxygen species and cadmium toxicity in the kidney

(2010) Glenda Gobe et al.   TOXICOLOGY LETTERS

The critical DNA damage by benzo(a)pyrene in lung tissues of smokers and approaches to preventing its formation

(2010) Kroum Alexandrov et al.   TOXICOLOGY LETTERS

Peroxisome Proliferator-Activated Receptor Alpha Target Genes

(2010) Maryam Rakhshandehroo et al.   PPAR Research

Environmental pollutants and the thyroid

(2009) Elizabeth N. Pearce et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

STAT3 deletion sensitizes cells to oxidative stress

(2009) Seán P. Barry et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Recognition by the Thyroid Hormone Receptor of Canonical DNA Response Elements

(2009) Ana Carolina Migliorini Figueira et al.   BIOCHEMISTRY

Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice

(2009) Melinda S. Yates et al.   CARCINOGENESIS

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer

(2009) Qianben Wang et al.   CELL

Modes of p53 Regulation

(2009) Jan-Philipp Kruse et al.   CELL

Differential Effects of Hypoxic Stress in Alveolar Epithelial Cells and Microvascular Endothelial Cells

(2009) Sara Signorelli et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Characterisation of Cadmium Chloride Induced Molecular and Functional Alterations in Airway Epithelial Cells

(2009) Efrat Forti et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Role of NF-κB in the Regulation of Cytochrome P450 Enzymes

(2009) Beshay Zordoky et al.   CURRENT DRUG METABOLISM

Involvement of Vitamin D Receptor in the Intestinal Induction of Human ABCB1

(2009) S. Tachibana et al.   DRUG METABOLISM AND DISPOSITION

IKK/NF-κB and STAT3 pathways: central signalling hubs in inflammation-mediated tumour promotion and metastasis

(2009) Julia Bollrath et al.   EMBO REPORTS

Stromal Progesterone Receptors Mediate Induction of Indian Hedgehog (IHH) in Uterine Epithelium and Its Downstream Targets in Uterine Stroma

(2009) Liz Simon et al.   ENDOCRINOLOGY

Negative feedback maintenance of heme homeostasis by its receptor, Rev-erb 

(2009) N. Wu et al.   GENES & DEVELOPMENT

Molecular cell biology of androgen receptor signalling

(2009) Nigel C. Bennett et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A Role for HSP70 in Protecting against Indomethacin-induced Gastric Lesions

(2009) Shintaro Suemasu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HSF1-mediated BAG3 Expression Attenuates Apoptosis in 4-Hydroxynonenal-treated Colon Cancer Cells via Stabilization of Anti-apoptotic Bcl-2 Proteins

(2009) Aaron T. Jacobs et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of Retinoic Acid Receptor-related Orphan Receptor α and γ Activity by 7-Oxygenated Sterol Ligands

(2009) Yongjun Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Peroxisome Proliferator-Activated Receptor  /  (PPAR / ) but Not PPAR  Serves as a Plasma Free Fatty Acid Sensor in Liver

(2009) L. M. Sanderson et al.   MOLECULAR AND CELLULAR BIOLOGY

Nuclear receptors CAR and PXR: Molecular, functional, and biomedical aspects

(2009) Alessandra di Masi et al.   MOLECULAR ASPECTS OF MEDICINE

Control of ovulation in mice by progesterone receptor-regulated gene networks

(2009) J. Kim et al.   MOLECULAR HUMAN REPRODUCTION

Identification of an Endogenous Ligand Bound to a Native Orphan Nuclear Receptor

(2009) Xiaohui Yuan et al.   PLoS One

TR4 nuclear receptor functions as a fatty acid sensor to modulate CD36 expression and foam cell formation

(2009) S. Xie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repression of DNA-binding dependent glucocorticoid receptor-mediated gene expression

(2009) K. A. Muzikar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The human glucocorticoid receptor: Molecular basis of biologic function

(2009) Nicolas C. Nicolaides et al.   STEROIDS

Identification of Chemical Compounds that Induce HIF-1α Activity

(2009) Menghang Xia et al.   TOXICOLOGICAL SCIENCES

Crosstalk between activated forms of the aryl hydrocarbon receptor and glucocorticoid receptor

(2009) Shao-Hung Wang et al.   TOXICOLOGY

Identification of potential mechanisms of toxicity after di-(2-ethylhexyl)-phthalate (DEHP) adult exposure in the liver using a systems biology approach

(2009) Alexandre Eveillard et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Role of Nrf1 in antioxidant response element-mediated gene expression and beyond

(2009) Madhurima Biswas et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nrf2 signaling and cell survival

(2009) Suryakant K. Niture et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inter-laboratory comparison of human renal proximal tubule (HK-2) transcriptome alterations due to Cyclosporine A exposure and medium exhaustion

(2009) Paul Jennings et al.   TOXICOLOGY IN VITRO

Mono-(2-ethylhexyl) phthalate induces NR4A subfamily and GIOT-1 gene expression, and suppresses CYP19 expression in human granulosa-like tumor cell line KGN

(2009) Shuji Ohno et al.   TOXICOLOGY LETTERS

ATF4-dependent transcription mediates signaling of amino acid limitation

(2009) Michael S. Kilberg et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Bone Morphogenetic Protein 7 (BMP7): A Critical Role in Kidney Development and a Putative Modulator of Kidney Injury

(2008) Patrick Archdeacon et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

Transcriptional induction of the human asparagine synthetase gene during the unfolded protein response does not require the ATF6 and IRE1/XBP1 arms of the pathway

(2008) Altin Gjymishka et al.   BIOCHEMICAL JOURNAL

Biology of hypoxia-inducible factor-2α in development and disease

(2008) S A Patel et al.   CELL DEATH AND DIFFERENTIATION

Roles of p53, Myc and HIF-1 in Regulating Glycolysis — the Seventh Hallmark of Cancer

(2008) S. J. Yeung et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Screening of 397 Chemicals and Development of a Quantitative Structure−Activity Relationship Model for Androgen Receptor Antagonism

(2008) Anne Marie Vinggaard et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Dexamethasone Induction of Murine CYP2B Genes Requires the Glucocorticoid Receptor

(2008) E. Audet-Walsh et al.   DRUG METABOLISM AND DISPOSITION

Interplay of Pregnane X receptor with Other Nuclear Receptors on Gene Regulation

(2008) Yun-Ping Lim et al.   Drug Metabolism and Pharmacokinetics

IL-8 and p53 are inversely regulated through JNK, p38 and NF-κB p65 in HepG2 cells during an inflammatory response

(2008) M. K. Rasmussen et al.   INFLAMMATION RESEARCH

Nrf1 and Nrf2 Play Distinct Roles in Activation of Antioxidant Response Element-dependent Genes

(2008) Makiko Ohtsuji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Orphan Nuclear Receptor, RORα, Regulates Gene Expression That Controls Lipid Metabolism

(2008) Patrick Lau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of the Per/Arnt/Sim Domains in Ligand-dependent Transformation of the Aryl Hydrocarbon Receptor

(2008) Anatoly Soshilov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATF3 Protects against Renal Ischemia-Reperfusion Injury

(2008) T. Yoshida et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

A Review of the Immunotoxicity of the Pesticide 3,4-Dichloropropionanalide

(2008) Keith D. Salazar et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS

WNT/β-catenin signaling in nephron progenitors and their epithelial progeny

(2008) Kai M. Schmidt-Ott et al.   KIDNEY INTERNATIONAL

Glucocorticoid Receptor Phosphorylation Differentially Affects Target Gene Expression

(2008) Weiwei Chen et al.   MOLECULAR ENDOCRINOLOGY

Minireview: The PGC-1 Coactivator Networks: Chromatin-Remodeling and Mitochondrial Energy Metabolism

(2008) Jiandie D. Lin   MOLECULAR ENDOCRINOLOGY

The carcinoGENOMICS project: Critical selection of model compounds for the development of omics-based in vitro carcinogenicity screening assays

(2008) M VINKEN et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Integration of metabolism and inflammation by lipid-activated nuclear receptors

(2008) Steven J. Bensinger et al.   NATURE

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS

Dibutyltin Disrupts Glucocorticoid Receptor Function and Impairs Glucocorticoid-Induced Suppression of Cytokine Production

(2008) Christel Gumy et al.   PLoS One

The orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II is a critical regulator of adipogenesis

(2008) Z. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Review of the expression of peroxisome proliferator-activated receptors alpha (PPARα), beta (PPARβ), and gamma (PPARγ) in rodent and human development

(2008) Barbara D. Abbott   REPRODUCTIVE TOXICOLOGY

The role and mechanism of progesterone receptor activation of extra-nuclear signaling pathways in regulating gene transcription and cell cycle progression

(2008) V BOONYARATANAKORNKIT et al.   STEROIDS

Cadmium-Induced Differential Toxicogenomic Response in Resistant and Sensitive Mouse Strains Undergoing Neurulation

(2008) Joshua F. Robinson et al.   TOXICOLOGICAL SCIENCES

Induction of drug metabolism: Species differences and toxicological relevance

(2008) Mark J. Graham et al.   TOXICOLOGY

Screening and detection of the in vitro agonistic activity of xenobiotics on the retinoic acid receptor

(2008) Ryo Kamata et al.   TOXICOLOGY IN VITRO

Application of toxicogenomics to study mechanisms of genotoxicity and carcinogenicity

(2008) Heidrun Ellinger-Ziegelbauer et al.   TOXICOLOGY LETTERS

Identification of COUP-TFII Orphan Nuclear Receptor as a Retinoic Acid–Activated Receptor

(2008) Schoen W Kruse et al.   PLOS BIOLOGY

The Nrf2–Keap1 defence pathway: Role in protection against drug-induced toxicity

(2007) Ian M. Copple et al.   TOXICOLOGY