Non-canonical NF-κB signaling activation and regulation: principles and perspectives

Dendritic Cells Require the NF- B2 Pathway for Cross-Presentation of Soluble Antigens

(2014) E. F. Lind et al.   JOURNAL OF IMMUNOLOGY

Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response

(2011) S. Gardam et al.   BLOOD

In TNF-stimulated Cells, RIPK1 Promotes Cell Survival by Stabilizing TRAF2 and cIAP1, which Limits Induction of Non-canonical NF-κB and Activation of Caspase-8

(2011) Ian E. Gentle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TNF -induced noncanonical NF- B activation is attenuated by RIP1 through stabilization of TRAF2

(2011) J.-Y. Kim et al.   JOURNAL OF CELL SCIENCE

Cleavage of NIK by the API2-MALT1 Fusion Oncoprotein Leads to Noncanonical NF- B Activation

(2011) S. Rosebeck et al.   SCIENCE

Classical and/or alternative NF- B pathway activation in multiple myeloma

(2010) Y. N. Demchenko et al.   BLOOD

Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor- B-inducing kinase while activating both canonical and alternative nuclear factor- B pathways

(2010) L. V. Pham et al.   BLOOD

Allosteric Regulation of the Ubiquitin:NIK and Ubiquitin:TRAF3 E3 Ligases by the Lymphotoxin-β Receptor

(2010) Hideki Sanjo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNAs modulate the noncanonical transcription factor NF-κB pathway by regulating expression of the kinase IKKα during macrophage differentiation

(2010) Tao Li et al.   NATURE IMMUNOLOGY

Negative Feedback in Noncanonical NF- B Signaling Modulates NIK Stability Through IKK -Mediated Phosphorylation

(2010) B. Razani et al.   Science Signaling

Mutations of multiple genes cause deregulation of NF-κB in diffuse large B-cell lymphoma

(2009) Mara Compagno et al.   NATURE

Frequent inactivation of A20 in B-cell lymphomas

(2009) Motohiro Kato et al.   NATURE

Autoregulatory feedback loops terminating the NF-κB response

(2009) Florian Renner et al.   TRENDS IN BIOCHEMICAL SCIENCES

TRAF2 and TRAF3 Signal Adapters Act Cooperatively to Control the Maturation and Survival Signals Delivered to B Cells by the BAFF Receptor

(2008) Sandra Gardam et al.   IMMUNITY

The Tumor Necrosis Factor Family Receptors RANK and CD40 Cooperatively Establish the Thymic Medullary Microenvironment and Self-Tolerance

(2008) Taishin Akiyama et al.   IMMUNITY

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1–TRAF2 complex to sensitize tumor cells to TNFα

(2008) James E. Vince et al.   JOURNAL OF CELL BIOLOGY

cIAP1 and cIAP2 Facilitate Cancer Cell Survival by Functioning as E3 Ligases that Promote RIP1 Ubiquitination

(2008) Mathieu J.M. Bertrand et al.   MOLECULAR CELL

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-κB signaling

(2008) Sivakumar Vallabhapurapu et al.   NATURE IMMUNOLOGY

Noncanonical NF-κB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK

(2008) Brian J Zarnegar et al.   NATURE IMMUNOLOGY

NIK overexpression amplifies, whereas ablation of its TRAF3-binding domain replaces BAFF:BAFF-R-mediated survival signals in B cells

(2008) Y. Sasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of canonical NF- B activation through the NIK-IKK complex pathway

(2008) B. Zarnegar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA