The role of autophagy in pulmonary hypertension: a double-edge sword

Quercetin induces autophagy via FOXO1-dependent pathways and autophagy suppression enhances quercetin-induced apoptosis in PASMCs in hypoxia

(2017) Yuanzhou He et al.   FREE RADICAL BIOLOGY AND MEDICINE

Acetylated cyclophilin A is a major mediator in hypoxia-induced autophagy and pulmonary vascular angiogenesis

(2017) Min Mao et al.   JOURNAL OF HYPERTENSION

Docetaxel Reverses Pulmonary Vascular Remodeling by Decreasing Autophagy and Resolves Right Ventricular Fibrosis

(2017) Yasmine F. Ibrahim et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Relationship Between the Right Ventricle and its Load in Pulmonary Hypertension

(2017) Anton Vonk Noordegraaf et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Emerging Mechanisms in Initiating and Terminating Autophagy

(2017) Manuela Antonioli et al.   TRENDS IN BIOCHEMICAL SCIENCES

Enhanced autophagy in pulmonary endothelial cells on exposure to HIV-Tat and morphine: Role in HIV-related pulmonary arterial hypertension

(2016) Pranjali Dalvi et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Mitophagy: a balance regulator of NLRP3 inflammasome activation

(2016) Min-Ji Kim et al.   BMB Reports

Inhibition of fatty acid synthase is protective in pulmonary hypertension

(2016) Neetu Singh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Classification of Pulmonary Hypertension

(2016) Ronald J. Oudiz   CARDIOLOGY CLINICS

Carfilzomib reverses pulmonary arterial hypertension

(2016) Xinhong Wang et al.   CARDIOVASCULAR RESEARCH

LC3/GABARAP family proteins: autophagy-(un)related functions

(2016) Marco B. E. Schaaf et al.   FASEB JOURNAL

Cancer stem cell metabolism: a potential target for cancer therapy

(2016) Abhijeet Deshmukh et al.   Molecular Cancer

Advances in Autophagy Regulatory Mechanisms

(2016) Laura Gallagher et al.   Cells

Endothelial Uncoupling Protein 2 Regulates Mitophagy and Pulmonary Hypertension During Intermittent Hypoxia

(2015) M. Haslip et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MTOR, PIK3C3, and autophagy: Signaling the beginning from the end

(2015) Michael J Munson et al.   Autophagy

Modulation of inflammation by autophagy: Consequences for human disease

(2015) Romana T. Netea-Maier et al.   Autophagy

Autophagy and oxidative stress in cardiovascular diseases

(2015) Yu Mei et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Adaptation and Remodelling of the Pulmonary Circulation in Pulmonary Hypertension

(2015) Mylène Vaillancourt et al.   CANADIAN JOURNAL OF CARDIOLOGY

Autophagy signal transduction by ATG proteins: from hierarchies to networks

(2015) Sebastian Wesselborg et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Molecular Mechanisms of Autophagy in the Cardiovascular System

(2015) D. Gatica et al.   CIRCULATION RESEARCH

Autophagy in Vascular Disease

(2015) G. R. Y. De Meyer et al.   CIRCULATION RESEARCH

Untangling Autophagy Measurements: All Fluxed Up

(2015) R. A. Gottlieb et al.   CIRCULATION RESEARCH

Mammalian target of rapamycin overexpression antagonizes chronic hypoxia-triggered pulmonary arterial hypertension via the autophagic pathway

(2015) LINGXIA LI et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Emerging strategies to effectively target autophagy in cancer

(2015) V W Rebecca et al.   ONCOGENE

High shear stress-induced pulmonary hypertension alleviated by endothelial progenitor cells independent of autophagy

(2015) Bi-Jun Xu et al.   World Journal of Pediatrics

Oxidative Stress, Redox Signaling, and Autophagy: Cell Death Versus Survival

(2014) Juliana Navarro-Yepes et al.   ANTIOXIDANTS & REDOX SIGNALING

Defining and measuring autophagosome flux—concept and reality

(2014) Ben Loos et al.   Autophagy

Impairment of autophagy in endothelial cells prevents shear-stress-induced increases in nitric oxide bioavailability

(2014) Leena P. Bharath et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Role of Endothelial Nitric Oxide Synthase and Collagen Metabolism in Right Ventricular Remodeling due to Pulmonary Hypertension

(2014) Suvd Nergui et al.   CIRCULATION JOURNAL

Basigin Mediates Pulmonary Hypertension by Promoting Inflammation and Vascular Smooth Muscle Cell Proliferation

(2014) Kimio Satoh et al.   CIRCULATION RESEARCH

Iloprost reverses established fibrosis in experimental right ventricular failure

(2014) Jose Gomez-Arroyo et al.   EUROPEAN RESPIRATORY JOURNAL

Increased Reactive Oxygen Species, Metabolic Maladaptation, and Autophagy Contribute to Pulmonary Arterial Hypertension–Induced Ventricular Hypertrophy and Diastolic Heart Failure

(2014) Dhawjbahadur K. Rawat et al.   HYPERTENSION

Apelin inhibits the proliferation and migration of rat PASMCsviathe activation of PI3K/Akt/mTOR signal and the inhibition of autophagy under hypoxia

(2014) Hongyu Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Autophagy as a modulator and target in prostate cancer

(2014) Jason M. Farrow et al.   Nature Reviews Urology

Mechanism of the Susceptibility of Remodeled Pulmonary Vessels to Drug‐Induced Cell Killing

(2014) Yasmine F. Ibrahim et al.   Journal of the American Heart Association

The Sugen 5416/Hypoxia Mouse Model of Pulmonary Hypertension Revisited: Long-Term Follow-Up

(2014) Sally H. Vitali et al.   Pulmonary Circulation

Adenosine Monophosphate–Activated Protein Kinase Is Required for Pulmonary Artery Smooth Muscle Cell Survival and the Development of Hypoxic Pulmonary Hypertension

(2013) Joyce Christina F. Ibe et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Cardiovascular autophagy

(2013) Sergio Lavandero et al.   Autophagy

Hypoxia-induced autophagy in endothelial cells: a double-edged sword in the progression of infantile haemangioma?

(2013) Gang Chen et al.   CARDIOVASCULAR RESEARCH

Mammalian Target of Rapamycin Complex 2 (mTORC2) Coordinates Pulmonary Artery Smooth Muscle Cell Metabolism, Proliferation, and Survival in Pulmonary Arterial Hypertension

(2013) Dmitry A. Goncharov et al.   CIRCULATION

Hungry for More

(2013) Dustin R. Fraidenburg et al.   CIRCULATION RESEARCH

Hypoxia-Inducible Factor-1α in Pulmonary Artery Smooth Muscle Cells Lowers Vascular Tone by Decreasing Myosin Light Chain Phosphorylation

(2013) Yu-Mee Kim et al.   CIRCULATION RESEARCH

Chloroquine Prevents Progression of Experimental Pulmonary Hypertension via Inhibition of Autophagy and Lysosomal Bone Morphogenetic Protein Type II Receptor Degradation

(2013) Lu Long et al.   CIRCULATION RESEARCH

Implications of autophagy for vascular smooth muscle cell function and plasticity

(2013) Joshua K. Salabei et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cross talk between NADPH oxidase and autophagy in pulmonary artery endothelial cells with intrauterine persistent pulmonary hypertension

(2012) Ru-Jeng Teng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Regulation and Functional Significance of Autophagy in Respiratory Cell Biology and Disease

(2012) Avignat S. Patel et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Beclin1: A role in membrane dynamics and beyond

(2012) Ellen Wirawan et al.   Autophagy

The Emerging Importance of Autophagy in Pulmonary Diseases

(2012) Kenji Mizumura et al.   CHEST

Autophagy mechanism of right ventricular remodeling in murine model of pulmonary artery constriction

(2011) Natia Qipshidze et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The monocrotaline model of pulmonary hypertension in perspective

(2011) Jose G. Gomez-Arroyo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis

(2011) Seon-Jin Lee et al.   Autophagy

Rodent models of pulmonary hypertension: harmonisation with the world health organisation’s categorisation of human PH

(2011) J. Ryan et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Autophagic Protein LC3B Confers Resistance against Hypoxia-induced Pulmonary Hypertension

(2010) Seon-Jin Lee et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Basic Science of Pulmonary Arterial Hypertension for Clinicians

(2010) Stephen L. Archer et al.   CIRCULATION

The Effects of Antiangiogenic Compound SU5416 in a Rat Model of Pulmonary Arterial Hypertension

(2010) Seiichiro Sakao et al.   RESPIRATION

Inflammation, Growth Factors, and Pulmonary Vascular Remodeling

(2009) Paul M. Hassoun et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY