Adenosine Monophosphate–Activated Protein Kinase Is Required for Pulmonary Artery Smooth Muscle Cell Survival and the Development of Hypoxic Pulmonary Hypertension

Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cell Proliferation Is Controlled by Forkhead Box M1

(2011) Aarti Raghavan et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

AMPK and autophagy get connected

(2011) D Grahame Hardie   EMBO JOURNAL

MCL1 meets its end during mitotic arrest

(2011) Scott E Millman et al.   EMBO REPORTS

mTOR is required for pulmonary arterial vascular smooth muscle cell proliferation under chronic hypoxia

(2011) Vera P. Krymskaya et al.   FASEB JOURNAL

Adenosine monophosphate-activated kinase α1 promotes endothelial barrier repair

(2011) Judy Creighton et al.   FASEB JOURNAL

AMP-activated protein kinase--an energy sensor that regulates all aspects of cell function

(2011) D. G. Hardie   GENES & DEVELOPMENT

Calpain mediates pulmonary vascular remodeling in rodent models of pulmonary hypertension, and its inhibition attenuates pathologic features of disease

(2011) Wanli Ma et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypoxia Triggers AMPK Activation through Reactive Oxygen Species-Mediated Activation of Calcium Release-Activated Calcium Channels

(2011) P. T. Mungai et al.   MOLECULAR AND CELLULAR BIOLOGY

Hypoxia Leads to Na,K-ATPase Downregulation via Ca2+ Release-Activated Ca2+ Channels and AMPK Activation

(2011) G. A. Gusarova et al.   MOLECULAR AND CELLULAR BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Survival advantage of AMPK activation to androgen-independent prostate cancer cells during energy stress

(2010) Rishi Raj Chhipa et al.   CELLULAR SIGNALLING

AMPK-independent induction of autophagy by cytosolic Ca2+ increase

(2010) Antje Grotemeier et al.   CELLULAR SIGNALLING

MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner

(2010) Marc Germain et al.   EMBO JOURNAL

Activation of AMP-activated Protein Kinase α1 Alleviates Endothelial Cell Apoptosis by Increasing the Expression of Anti-apoptotic Proteins Bcl-2 and Survivin

(2010) Chao Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Pharmacological Activator of AMP-Activated Protein Kinase Protects Hypoxic Neurons in a Concentration-Dependent Manner

(2010) Xiaolu Zhang et al.   NEUROCHEMICAL RESEARCH

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

GX15-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy

(2010) N Heidari et al.   Cell Death & Disease

Ion Channel Regulation by AMPK

(2009) A. Mark Evans et al.   Annals of the New York Academy of Sciences

AMP-activated protein kinase-dependent and -independent mechanisms underlying in vitro antiglioma action of compound C

(2009) Ljubica Vucicevic et al.   BIOCHEMICAL PHARMACOLOGY

Protective role of the antidiabetic drug metformin against chronic experimental pulmonary hypertension

(2009) C Agard et al.   BRITISH JOURNAL OF PHARMACOLOGY

AMP-activated protein kinase confers protection against TNF-α-induced cardiac cell death

(2009) Girish Kewalramani et al.   CARDIOVASCULAR RESEARCH

ACCF/AHA 2009 Expert Consensus Document on Pulmonary Hypertension

(2009) et al.   CIRCULATION

Hypoxic activation of AMPK is dependent on mitochondrial ROS but independent of an increase in AMP/ATP ratio

(2009) Brooke M. Emerling et al.   FREE RADICAL BIOLOGY AND MEDICINE

AMPK: Lessons from transgenic and knockout animals

(2009) Benoit Viollet   Frontiers in Bioscience-Landmark

The role of AMP-activated protein kinase in the cardiovascular system

(2009) Daisuke Nagata et al.   HYPERTENSION RESEARCH

Persistent eNOS activation secondary to caveolin-1 deficiency induces pulmonary hypertension in mice and humans through PKG nitration

(2009) You-Yang Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

 1-AMP-Activated Protein Kinase Regulates Hypoxia-Induced Na,K-ATPase Endocytosis via Direct Phosphorylation of Protein Kinase C 

(2009) G. A. Gusarova et al.   MOLECULAR AND CELLULAR BIOLOGY

AMP-activated protein kinase promotes human prostate cancer cell growth and survival

(2009) H. U. Park et al.   MOLECULAR CANCER THERAPEUTICS

When apoptosis meets autophagy: deciding cell fate after trauma and sepsis

(2009) Ya-Ching Hsieh et al.   TRENDS IN MOLECULAR MEDICINE

AMP-activated protein kinase in skeletal muscle: From structure and localization to its role as a master regulator of cellular metabolism

(2008) C. A. Witczak et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

AMP-activated Protein Kinase Phosphorylates and Desensitizes Smooth Muscle Myosin Light Chain Kinase

(2008) Sandrine Horman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMP-activated Protein Kinase Inhibits Transforming Growth Factor-β-induced Smad3-dependent Transcription and Myofibroblast Transdifferentiation

(2008) Rangnath Mishra et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

How to Live Long and Prosper: Autophagy, Mitochondria, and Aging

(2008) Wei-Lien Yen et al.   PHYSIOLOGY

The BCL-2 protein family: opposing activities that mediate cell death

(2007) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY