AMP-activated protein kinase suppresses urate crystal-induced inflammation and transduces colchicine effects in macrophages

Alcohol Quantity and Type on Risk of Recurrent Gout Attacks: An Internet-based Case-crossover Study

(2014) Tuhina Neogi et al.   AMERICAN JOURNAL OF MEDICINE

Uric acid-dependent inhibition of AMP kinase induces hepatic glucose production in diabetes and starvation: evolutionary implications of the uricase loss in hominids

(2014) Christina Cicerchi et al.   FASEB JOURNAL

Identification of 5′ AMP-activated Kinase as a Target of Reactive Aldehydes during Chronic Ingestion of High Concentrations of Ethanol

(2014) Colin T. Shearn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adenosine 5'-Monophosphate-Activated Protein Kinase Promotes Macrophage Polarization to an Anti-Inflammatory Functional Phenotype

(2014) D. Sag et al.   JOURNAL OF IMMUNOLOGY

Prophylaxis for acute gout flares after initiation of urate-lowering therapy

(2014) A. Latourte et al.   RHEUMATOLOGY

Brief Report: Granulocyte-Macrophage Colony-Stimulating Factor Drives Monosodium Urate Monohydrate Crystal-Induced Inflammatory Macrophage Differentiation and NLRP3 Inflammasome Up-Regulation in an In Vivo Mouse Model

(2014) Odette M. Shaw et al.   Arthritis & Rheumatology

Modulatory mechanisms controlling the NLRP3 inflammasome in inflammation: recent developments

(2013) Moritz Haneklaus et al.   CURRENT OPINION IN IMMUNOLOGY

AMPK, insulin resistance, and the metabolic syndrome

(2013) Neil B. Ruderman et al.   JOURNAL OF CLINICAL INVESTIGATION

Metabolism of inflammation limited by AMPK and pseudo-starvation

(2013) Luke A. J. O'Neill et al.   NATURE

AMPK: mediating the metabolic effects of salicylate-based drugs?

(2013) Gregory R. Steinberg et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Comorbidities of Gout and Hyperuricemia in the US General Population: NHANES 2007-2008

(2012) Yanyan Zhu et al.   AMERICAN JOURNAL OF MEDICINE

Purine-rich foods intake and recurrent gout attacks

(2012) Yuqing Zhang et al.   ANNALS OF THE RHEUMATIC DISEASES

TLR-induced NF-κB activation regulates NLRP3 expression in murine macrophages

(2012) Yu Qiao et al.   FEBS LETTERS

AMPK regulates macrophage polarization in adipose tissue inflammation and NASH

(2012) Shih-Yen Weng et al.   JOURNAL OF HEPATOLOGY

Fueling the flame: bioenergy couples metabolism and inflammation

(2012) T. F. Liu et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A role for the NLRP3 inflammasome in metabolic diseases—did Warburg miss inflammation?

(2012) Haitao Wen et al.   NATURE IMMUNOLOGY

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

GM-CSF Priming Drives Bone Marrow-Derived Macrophages to a Pro-Inflammatory Pattern and Downmodulates PGE2 in Response to TLR2 Ligands

(2012) Carlos Arterio Sorgi et al.   PLoS One

Counteracting Roles of AMP Deaminase and AMP Kinase in the Development of Fatty Liver

(2012) Miguel A. Lanaspa et al.   PLoS One

The Ancient Drug Salicylate Directly Activates AMP-Activated Protein Kinase

(2012) S. A. Hawley et al.   SCIENCE

Enhanced interleukin-1β production of PBMCs from patients with gout after stimulation with Toll-like receptor-2 ligands and urate crystals

(2012) Eleni E Mylona et al.   ARTHRITIS RESEARCH & THERAPY

Prevalence of Contraindications and Prescription of Pharmacologic Therapies for Gout

(2011) Robert T. Keenan et al.   AMERICAN JOURNAL OF MEDICINE

Chondrocyte AMP-activated protein kinase activity suppresses matrix degradation responses to proinflammatory cytokines interleukin-1β and tumor necrosis factor α

(2011) Robert Terkeltaub et al.   ARTHRITIS AND RHEUMATISM

Insulin resistance due to nutrient excess

(2011) Asish K. Saha et al.   CELL CYCLE

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

(2011) Antero Salminen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Cardiac and metabolic changes in long-term high fructose-fat fed rats with severe obesity and extensive intramyocardial lipid accumulation

(2010) Lene N. Axelsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

High versus low dosing of oral colchicine for early acute gout flare: Twenty-four-hour outcome of the first multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-comparison colchicine study

(2010) Robert A. Terkeltaub et al.   ARTHRITIS AND RHEUMATISM

Engagement of fatty acids with toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis

(2010) Leo A. B. Joosten et al.   ARTHRITIS AND RHEUMATISM

Interleukin-1β activation during acute joint inflammation: A limited role for the NLRP3 inflammasome in vivo

(2010) Leo A.B. Joosten et al.   JOINT BONE SPINE

Macrophage α1 AMP-activated Protein Kinase (α1AMPK) Antagonizes Fatty Acid-induced Inflammation through SIRT1

(2010) Zhenggang Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK controls the speed of microtubule polymerization and directional cell migration through CLIP-170 phosphorylation

(2010) Atsushi Nakano et al.   NATURE CELL BIOLOGY

Mechanisms of inflammation in gout

(2010) Nathalie Busso et al.   ARTHRITIS RESEARCH & THERAPY

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

AMP-activated protein kinase in skeletal muscle: From structure and localization to its role as a master regulator of cellular metabolism

(2008) C. A. Witczak et al.   CELLULAR AND MOLECULAR LIFE SCIENCES