Insulin resistance due to nutrient excess

Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy

(2016) Sean M. Armour et al.   Aging-US

Novel roles for JNK1 in metabolism

(2016) Bengt F. Belgardt et al.   Aging-US

P66SHC and Ageing: ROS and TOR?

(2016) Giovambattista Pani   Aging-US

The evolution of insulin resistance in muscle of the glucose infused rat

(2011) Amanda E. Brandon et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Transcriptional Control of Cellular Metabolism by mTOR Signaling

(2011) J. L. Yecies et al.   CANCER RESEARCH

Calorie restriction: Decelerating mTOR-driven aging from cells to organisms (including humans)

(2011) Mikhail V Blagosklonny   CELL CYCLE

Adrenergic Regulation of AMP-activated Protein Kinase in Brown Adipose Tissuein Vivo

(2011) Thomas Pulinilkunnil et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

Dietary Leucine - An Environmental Modifier of Insulin Resistance Acting on Multiple Levels of Metabolism

(2011) Yazmin Macotela et al.   PLoS One

mTOR couples cellular nutrient sensing to organismal metabolic homeostasis

(2011) Jessica J. Howell et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Central Nervous System Nutrient Signaling: The Regulation of Energy Balance and the Future of Dietary Therapies

(2010) M.A. Stefater et al.   Annual Review of Nutrition

Comparing and contrasting the roles of AMPK and SIRT1 in metabolic tissues

(2010) Marcella Fulco et al.   CELL CYCLE

Activation of AMP-Activated Protein Kinase Inhibits Oxidized LDL-Triggered Endoplasmic Reticulum Stress In Vivo

(2010) Y. Dong et al.   DIABETES

Downregulation of AMPK Accompanies Leucine- and Glucose-Induced Increases in Protein Synthesis and Insulin Resistance in Rat Skeletal Muscle

(2010) A. K. Saha et al.   DIABETES

The PP1-R6 protein phosphatase holoenzyme is involved in the glucose-induced dephosphorylation and inactivation of AMP-activated protein kinase, a key regulator of insulin secretion, in MIN6 β cells

(2010) Luisa Garcia-Haro et al.   FASEB JOURNAL

Structure of the Human mTOR Complex I and Its Implications for Rapamycin Inhibition

(2010) Calvin K. Yip et al.   MOLECULAR CELL

Regulation of the mTOR Complex 1 Pathway by Nutrients, Growth Factors, and Stress

(2010) Shomit Sengupta et al.   MOLECULAR CELL

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Concurrent regulation of AMP-activated protein kinase and SIRT1 in mammalian cells

(2008) Gabriela Suchankova et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SirT1 Gain of Function Increases Energy Efficiency and Prevents Diabetes in Mice

(2008) Alexander S. Banks et al.   Cell Metabolism

SIRT1 Modulation of the Acetylation Status, Cytosolic Localization, and Activity of LKB1

(2008) Fan Lan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SIRT1 Regulates Hepatocyte Lipid Metabolism through Activating AMP-activated Protein Kinase

(2008) Xiuyun Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY