Engagement of fatty acids with toll-like receptor 2 drives interleukin-1β production via the ASC/caspase 1 pathway in monosodium urate monohydrate crystal-induced gouty arthritis

Update on gout: new therapeutic strategies and options

(2010) Robert Terkeltaub   Nature Reviews Rheumatology

The interleukin 1 inhibitor rilonacept in treatment of chronic gouty arthritis: results of a placebo-controlled, monosequence crossover, non-randomised, single-blind pilot study

(2009) R Terkeltaub et al.   ANNALS OF THE RHEUMATIC DISEASES

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Immunological and Inflammatory Functions of the Interleukin-1 Family

(2009) Charles A. Dinarello   Annual Review of Immunology

Inflammatory arthritis in caspase 1 gene–deficient mice: Contribution of proteinase 3 to caspase 1–independent production of bioactive interleukin-1β

(2009) Leo A. B. Joosten et al.   ARTHRITIS AND RHEUMATISM

Fungal Zymosan and Mannan Activate the Cryopyrin Inflammasome

(2009) Mohamed Lamkanfi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inflammatory Role of ASC in Antigen-Induced Arthritis Is Independent of Caspase-1, NALP-3, and IPAF

(2009) L. Kolly et al.   JOURNAL OF IMMUNOLOGY

Bypassing Pathogen‐Induced Inflammasome Activation for the Regulation of Interleukin‐1β Production by the Fungal PathogenCandida albicans

(2009) Frank L. van de Veerdonk et al.   JOURNAL OF INFECTIOUS DISEASES

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

Alcohol Functionally Upregulates Toll-Like Receptor 2 in Airway Epithelial Cells

(2008) Kristina L. Bailey et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Alcohol and lipid metabolism

(2008) Margaret Sozio et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Crystals of monosodium urate monohydrate enhance lipopolysaccharide-induced release of interleukin 1  by mononuclear cells through a caspase 1-mediated process

(2008) E J Giamarellos-Bourboulis et al.   ANNALS OF THE RHEUMATIC DISEASES

Stimulation of TLR2 and TLR4 differentially skews the balance of T cells in a mouse model of arthritis

(2008) Shahla Abdollahi-Roodsaz et al.   JOURNAL OF CLINICAL INVESTIGATION

Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants

(2008) Stephanie C. Eisenbarth et al.   NATURE

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

(2008) Annett Halle et al.   NATURE IMMUNOLOGY

Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis

(2008) Leo A. B. Joosten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA