Review: Using physiologically based models to predict population responses to phytochemicals by wild vertebrate herbivores

Multivariate Climate Change Can Favor Large Herbivore Body Size in Food Webs

(2018) Lauren M. Smith-Ramesh et al.   AMERICAN NATURALIST

Synthesizing multiple data types for biological conservation using integrated population models

(2018) Elise F. Zipkin et al.   BIOLOGICAL CONSERVATION

Understanding the GUT microbiome-liver axis in xenobiotic biotransformation

(2018) Julia Yue Cui   Drug Metabolism and Pharmacokinetics

Assessment of Animal-Based Methods Used for Estimating and Monitoring Rangeland Herbivore Diet Composition

(2018) Sarah Garnick et al.   Rangeland Ecology & Management

Fish reproductive-energy output increases disproportionately with body size

(2018) Diego R. Barneche et al.   SCIENCE

An Improved Single-Channel Method to Retrieve Land Surface Temperature from the Landsat-8 Thermal Band

(2018) Jordi Cristóbal et al.   Remote Sensing

The complexity of interacting nutritional drivers behind food selection, a review of northern cervids

(2018) Annika M. Felton et al.   Ecosphere

FibroChip, a Functional DNA Microarray to Monitor Cellulolytic and Hemicellulolytic Activities of Rumen Microbiota

(2018) Sophie Comtet-Marre et al.   Frontiers in Microbiology

Beyond drug-drug interactions: effects of transporter inhibition on endobiotics, nutrients and toxins

(2017) Eve-Irene Lepist et al.   Expert Opinion on Drug Metabolism & Toxicology

Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics

(2017) María Santos et al.   GENETICS IN MEDICINE

Study protocol on the role of intestinal microbiota in colorectal cancer treatment: a pathway to personalized medicine 2.0

(2017) R. Aarnoutse et al.   INTERNATIONAL JOURNAL OF COLORECTAL DISEASE

Ninety-nine de novo assembled genomes from the moose (Alces alces) rumen microbiome provide new insights into microbial plant biomass degradation

(2017) Olov Svartström et al.   ISME Journal

Transcriptional responses of detoxification genes to four plant allelochemicals in Aphis gossypii

(2017) Fen Li et al.   JOURNAL OF ECONOMIC ENTOMOLOGY

Genetic monitoring of an endangered species recovery: demographic and genetic trends for reintroduced pygmy rabbits (Brachylagus idahoensis)

(2017) Stephanie M. DeMay et al.   JOURNAL OF MAMMALOGY

Ambient temperature-mediated changes in hepatic gene expression of a mammalian herbivore (Neotoma lepida )

(2017) Patrice Kurnath Connors et al.   MOLECULAR ECOLOGY

Gut microbiome interactions with drug metabolism, efficacy, and toxicity

(2017) Ian D. Wilson et al.   Translational Research

Moose selecting for specific nutritional composition of birch places limits on food acceptability

(2017) Hilde K. Wam et al.   Ecology and Evolution

Arctic greening from warming promotes declines in caribou populations

(2017) Per Fauchald et al.   Science Advances

SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules

(2017) Antoine Daina et al.   Scientific Reports

Using energy budgets to combine ecology and toxicology in a mammalian sentinel species

(2017) Jean-Pierre W. Desforges et al.   Scientific Reports

The effect of insecticide synergist treatment on genome-wide gene expression in a polyphagous pest

(2017) Simon Snoeck et al.   Scientific Reports

Forecasting disturbance effects on wildlife: tolerance does not mitigate effects of increased recreation on wildlands

(2016) B. P. Pauli et al.   ANIMAL CONSERVATION

Evodia alkaloids suppress gluconeogenesis and lipogenesis by activating the constitutive androstane receptor

(2016) Lushan Yu et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Predicting Drug Extraction in the Human Gut Wall: Assessing Contributions from Drug Metabolizing Enzymes and Transporter Proteins using Preclinical Models

(2016) Sheila Annie Peters et al.   CLINICAL PHARMACOKINETICS

Coupling bio-logging with nutritional geometry to reveal novel insights into the foraging behaviour of a plunge-diving marine predator

(2016) Gabriel E Machovsky-Capuska et al.   NEW ZEALAND JOURNAL OF MARINE AND FRESHWATER RESEARCH

The influence of plant defensive chemicals, diet composition, and winter severity on the nutritional condition of a free-ranging, generalist herbivore

(2016) Grace L. Parikh et al.   OIKOS

Long-read sequence assembly of the gorilla genome

(2016) D. Gordon et al.   SCIENCE

Mechanistic description of population dynamics using dynamic energy budget theory incorporated into integral projection models

(2016) Isabel M. Smallegange et al.   Methods in Ecology and Evolution

Identifying Malaria Transmission Foci for Elimination Using Human Mobility Data

(2016) Nick W. Ruktanonchai et al.   PLoS Computational Biology

The Nutritional Balancing Act of a Large Herbivore: An Experiment with Captive Moose (Alces alces L)

(2016) Annika M. Felton et al.   PLoS One

The role of lipid and carbohydrate digestive enzyme inhibitors in the management of obesity: a review of current and emerging therapeutic agents

(2016) Sonia Tucci   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

From big data analysis to personalized medicine for all: challenges and opportunities

(2015) Akram Alyass et al.   BMC Medical Genomics

Modeling trade-offs between plant fiber and toxins: a framework for quantifying risks perceived by foraging herbivores

(2015) Meghan J. Camp et al.   ECOLOGY

Inoculation of tannin-degrading bacteria into novel hosts increases performance on tannin-rich diets

(2015) Kevin D. Kohl et al.   ENVIRONMENTAL MICROBIOLOGY

Natural Selection at the Brush-Border: Adaptations to Carbohydrate Diets in Humans and Other Mammals

(2015) Chiara Pontremoli et al.   Genome Biology and Evolution

Using in Vitro and in Vivo Models To Evaluate the Oral Bioavailability of Nutraceuticals

(2015) Yuwen Ting et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

New insights: animal-borne cameras and accelerometers reveal the secret lives of cryptic species

(2015) Graeme C. Hays   JOURNAL OF ANIMAL ECOLOGY

Monoterpenes as inhibitors of digestive enzymes and counter-adaptations in a specialist avian herbivore

(2015) Kevin D. Kohl et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

Analysis of Physicochemical Properties for Drugs of Natural Origin

(2015) David Camp et al.   JOURNAL OF NATURAL PRODUCTS

Use of a Physiologically Based Pharmacokinetic Model for Quantitative Prediction of Drug–Drug Interactions via CYP3A4 and Estimation of the Intestinal Availability of CYP3A4 Substrates

(2015) Yoko Mano et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

Organs-on-chips at the frontiers of drug discovery

(2015) Eric W. Esch et al.   NATURE REVIEWS DRUG DISCOVERY

NIH working group report-using genomic information to guide weight management: From universal to precision treatment

(2015) Molly S. Bray et al.   Obesity

A plant toxin mediated mechanism for the lag in snowshoe hare population recovery following cyclic declines

(2015) Donald L. DeAngelis et al.   OIKOS

Predictive genomics: A cancer hallmark network framework for predicting tumor clinical phenotypes using genome sequencing data

(2015) Edwin Wang et al.   SEMINARS IN CANCER BIOLOGY

Predation risk tradeoffs in prey: effects on energy and behaviour

(2015) Marwa Khater et al.   Theoretical Ecology

Differences and similarities in hepatic lipogenesis, gluconeogenesis and oxidative imbalance in mice fed diets rich in fructose or sucrose

(2015) Alini Schultz et al.   Food & Function

A toolbox for studying thermal heterogeneity across spatial scales: from unmanned aerial vehicle imagery to landscape metrics

(2015) Emile Faye et al.   Methods in Ecology and Evolution

The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice

(2014) Samantha M. Solon-Biet et al.   Cell Metabolism

Gut microbes of mammalian herbivores facilitate intake of plant toxins

(2014) Kevin D. Kohl et al.   ECOLOGY LETTERS

Plant protein and secondary metabolites influence diet selection in a mammalian specialist herbivore

(2014) Amy C. Ulappa et al.   JOURNAL OF MAMMALOGY

Detection of an endogenous urinary biomarker associated with CYP2D6 activity using global metabolomics

(2014) Jessica Tay-Sontheimer et al.   PHARMACOGENOMICS

Loss of animal seed dispersal increases extinction risk in a tropical tree species due to pervasive negative density dependence across life stages

(2014) T. T. Caughlin et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Impacts of Human Disturbance on CapercaillieTetrao urogallusDistribution and Demography in Scottish Woodland

(2014) Robert Moss et al.   WILDLIFE BIOLOGY

Combining the ‘bottom up’ and ‘top down’ approaches in pharmacokinetic modelling: fitting PBPK models to observed clinical data

(2013) Nikolaos Tsamandouras et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Seasonal differences in the relative importance of specific phenolics and twig morphology result in contrasting patterns of foraging by a generalist herbivore

(2013) C. Stolter et al.   CANADIAN JOURNAL OF ZOOLOGY

Dynamic energy budgets in population ecotoxicology: Applications and outlook

(2013) Tjalling Jager et al.   ECOLOGICAL MODELLING

Phytochemistry predicts habitat selection by an avian herbivore at multiple spatial scales

(2013) Graham G. Frye et al.   ECOLOGY

The importance of long-distance seed dispersal for the demography and distribution of a canopy tree species

(2013) T. Trevor Caughlin et al.   ECOLOGY

Building integral projection models: a user's guide

(2013) Mark Rees et al.   JOURNAL OF ANIMAL ECOLOGY

A Pharm-Ecological Perspective of Terrestrial and Aquatic Plant-Herbivore Interactions

(2013) Jennifer Sorensen Forbey et al.   JOURNAL OF CHEMICAL ECOLOGY

Whole-body protein turnover reveals the cost of detoxification of secondary metabolites in a vertebrate browser

(2013) Jessie Au et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism

(2013) Gijs den Besten et al.   JOURNAL OF LIPID RESEARCH

Translating nutritional ecology from the laboratory to the field: milestones in linking plant chemistry to population regulation in mammalian browsers

(2013) Jane L. DeGabriel et al.   OIKOS

30 Days in the Life: Daily Nutrient Balancing in a Wild Chacma Baboon

(2013) Caley A. Johnson et al.   PLoS One

Draft genome sequence of the Tibetan antelope

(2013) Ri-Li Ge et al.   Nature Communications

Geometric analysis of macronutrient selection in breeds of the domestic dog, Canis lupus familiaris

(2012) Adrian K. Hewson-Hughes et al.   BEHAVIORAL ECOLOGY

Mechanisms for Eliminating Monoterpenes of Sagebrush by Specialist and Generalist Rabbits

(2012) Lisa A. Shipley et al.   JOURNAL OF CHEMICAL ECOLOGY

Temperature-dependent toxicity in mammals with implications for herbivores: a review

(2012) M. Denise Dearing   JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY

Whole-genome sequencing of giant pandas provides insights into demographic history and local adaptation

(2012) Shancen Zhao et al.   NATURE GENETICS

Use of faecal pellet size to differentiate age classes in female Svalbard reindeerRangifer tarandus platyrhynchus

(2012) C-Jae C. Morden et al.   WILDLIFE BIOLOGY

Representing the acquisition and use of energy by individuals in agent-based models of animal populations

(2012) Richard M. Sibly et al.   Methods in Ecology and Evolution

Nutritional geometry: gorillas prioritize non-protein energy while consuming surplus protein

(2011) J. M. Rothman et al.   Biology Letters

Inhibition of Snowshoe Hare Succinate Dehydrogenase Activity as a Mechanism of Deterrence for Papyriferic Acid in Birch

(2011) Jennifer Sorensen Forbey et al.   JOURNAL OF CHEMICAL ECOLOGY

Geometric analysis of macronutrient selection in the adult domestic cat, Felis catus

(2011) A. K. Hewson-Hughes et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Modeling the dynamics of woody plant–herbivore interactions with age-dependent toxicity

(2011) Rongsong Liu et al.   JOURNAL OF MATHEMATICAL BIOLOGY

Testing the diet-breadth trade-off hypothesis: differential regulation of novel plant secondary compounds by a specialist and a generalist herbivore

(2011) A-M. Torregrossa et al.   OECOLOGIA

Modeling Effects of Environmental Change on Wolf Population Dynamics, Trait Evolution, and Life History

(2011) T. Coulson et al.   SCIENCE

The impact of tannins on protein, dry matter, and energy digestion in moose (Alces alces)

(2010) D. E. Spalinger et al.   CANADIAN JOURNAL OF ZOOLOGY

Applications of Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation During Regulatory Review

(2010) P Zhao et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Palatability mapping: a koala's eye view of spatial variation in habitat quality

(2010) Ben D. Moore et al.   ECOLOGY

Exploitation of dietary tannins to improve rumen metabolism and ruminant nutrition

(2010) Amlan K Patra et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Quercetin: A potential drug to reverse multidrug resistance

(2010) Chen Chen et al.   LIFE SCIENCES

Integrating the costs of plant toxins and predation risk in foraging decisions of a mammalian herbivore

(2010) Sahar N. Kirmani et al.   OECOLOGIA

Dietary flavonoids in cancer therapy and prevention: Substrates and inhibitors of cytochrome P450 CYP1 enzymes

(2010) Vasilis P. Androutsopoulos et al.   PHARMACOLOGY & THERAPEUTICS

Effect of Enhanced Nutrition on Mule Deer Population Rate of Change

(2010) Chad J. Bishop et al.   WILDLIFE MONOGRAPHS

Protein content of diets dictates the daily energy intake of a free-ranging primate

(2009) Annika M. Felton et al.   BEHAVIORAL ECOLOGY

The effects of plant defensive chemistry on nutrient availability predict reproductive success in a mammal

(2009) Jane L. DeGabriel et al.   ECOLOGY

Herbivore metabolism and stoichiometry each constrain herbivory at different organizational scales across ecosystems

(2009) Helmut Hillebrand et al.   ECOLOGY LETTERS

Plant Toxicity, Adaptive Herbivory, and Plant Community Dynamics

(2009) Zhilan Feng et al.   ECOSYSTEMS

Nutritional toxicology of mammals: regulated intake of plant secondary compounds

(2009) Ann-Marie Torregrossa et al.   FUNCTIONAL ECOLOGY

Nutrition integrates environmental responses of ungulates

(2009) Katherine L. Parker et al.   FUNCTIONAL ECOLOGY

Nutrition, ecology and nutritional ecology: toward an integrated framework

(2009) David Raubenheimer et al.   FUNCTIONAL ECOLOGY

Revisiting the dietary niche: When is a mammalian herbivore a specialist?

(2009) L. A. Shipley et al.   INTEGRATIVE AND COMPARATIVE BIOLOGY

Declines in moose population density at Isle Royle National Park, MI, USA and accompanied changes in landscape patterns

(2009) Nathan R. De Jager et al.   LANDSCAPE ECOLOGY

An overview of the relations between polymorphisms in drug metabolising enzymes and drug transporters and survival after cancer drug treatment

(2008) Corine Ekhart et al.   CANCER TREATMENT REVIEWS

Protein-leverage in Mice: The Geometry of Macronutrient Balancing and Consequences for Fat Deposition

(2008) Allan Sørensen et al.   Obesity

A simple, integrative assay to quantify nutritional quality of browses for herbivores

(2008) Jane L. DeGabriel et al.   OECOLOGIA

Ability of whole-genome SNP arrays to capture ‘must have’ pharmacogenomic variants

(2008) Eric J Peters et al.   PHARMACOGENOMICS