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Title
Macrophage subsets and microglia in multiple sclerosis
Authors
Keywords
Macrophage, Microglia, Polarization, Neuroinflammation, CNS repair, Multiple sclerosis
Journal
ACTA NEUROPATHOLOGICA
Volume 128, Issue 2, Pages 191-213
Publisher
Springer Nature
Online
2014-06-21
DOI
10.1007/s00401-014-1310-2
References
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Note: Only part of the references are listed.- Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain
- (2014) Monica R.P. Elmore et al. NEURON
- Neuro-Anatomical Evidence Indicating Indirect Modulation of Macrophages by Vagal Efferents in the Intestine but Not in the Spleen
- (2014) Cathy Cailotto et al. PLoS One
- Network-Based Multiple Sclerosis Pathway Analysis with GWAS Data from 15,000 Cases and 30,000 Controls
- (2013) Sergio E. Baranzini et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Interleukin-4- and Interleukin-13-Mediated Alternatively Activated Macrophages: Roles in Homeostasis and Disease
- (2013) Steven J. Van Dyken et al. Annual Review of Immunology
- IFN-γ-dependent activation of the brain’s choroid plexus for CNS immune surveillance and repair
- (2013) Gilad Kunis et al. BRAIN
- Meningeal and choroid plexus cells—Novel drug targets for CNS disorders
- (2013) Mike Dragunow BRAIN RESEARCH
- Nr4a1-Dependent Ly6Clow Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal
- (2013) Leo M. Carlin et al. CELL
- Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus
- (2013) Ravid Shechter et al. IMMUNITY
- Monocyte/macrophages and their role in HIV neuropathogenesis
- (2013) Tricia H. Burdo et al. IMMUNOLOGICAL REVIEWS
- Macrophages in inflammatory multiple sclerosis lesions have an intermediate activation status
- (2013) Daphne YS Vogel et al. Journal of Neuroinflammation
- Macrophage biology in development, homeostasis and disease
- (2013) Thomas A. Wynn et al. NATURE
- Origin of monocytes and macrophages in a committed progenitor
- (2013) Jan Hettinger et al. NATURE IMMUNOLOGY
- A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation
- (2013) Tobias Goldmann et al. NATURE NEUROSCIENCE
- Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways
- (2013) Katrin Kierdorf et al. NATURE NEUROSCIENCE
- Identification of a unique TGF-β–dependent molecular and functional signature in microglia
- (2013) Oleg Butovsky et al. NATURE NEUROSCIENCE
- M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination
- (2013) Veronique E Miron et al. NATURE NEUROSCIENCE
- Review: Microglia in protein aggregation disorders: friend or foe?
- (2013) S. M. Gentleman NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Feasibility of the Use of Combinatorial Chemokine Arrays to Study Blood and CSF in Multiple Sclerosis
- (2013) Keith R. Edwards et al. PLoS One
- Microglia: Scapegoat, Saboteur, or Something Else?
- (2013) A. Aguzzi et al. SCIENCE
- Myelin alters the inflammatory phenotype of macrophages by activating PPARs
- (2013) Jeroen FJ Bogie et al. Acta Neuropathologica Communications
- Reflex Principles of Immunological Homeostasis
- (2012) Ulf Andersson et al. Annual Review of Immunology
- Meningeal and cortical grey matter pathology in multiple sclerosis
- (2012) Bogdan F Gh Popescu et al. BMC Neurology
- Neuroinflammation after traumatic brain injury: Opportunities for therapeutic intervention
- (2012) Alok Kumar et al. BRAIN BEHAVIOR AND IMMUNITY
- Lesional Accumulation of CD163+ Macrophages/microglia in Rat Traumatic Brain Injury
- (2012) Zhiren Zhang et al. BRAIN RESEARCH
- Regional Neural Activation Defines a Gateway for Autoreactive T Cells to Cross the Blood-Brain Barrier
- (2012) Yasunobu Arima et al. CELL
- Transmigration of macrophages across the choroid plexus epithelium in response to the feline immunodeficiency virus
- (2012) Rick B. Meeker et al. CELL AND TISSUE RESEARCH
- Rejuvenation of Regeneration in the Aging Central Nervous System
- (2012) Julia M. Ruckh et al. Cell Stem Cell
- Secreted protein lipocalin-2 promotes microglial M1 polarization
- (2012) Eunha Jang et al. FASEB JOURNAL
- Comparison of polarization properties of human adult microglia and blood-derived macrophages
- (2012) Bryce A. Durafourt et al. GLIA
- Lipocalin 2 is a novel immune mediator of experimental autoimmune encephalomyelitis pathogenesis and is modulated in multiple sclerosis
- (2012) Jennifer L. Berard et al. GLIA
- Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis
- (2012) Simon Yona et al. IMMUNITY
- Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS
- (2012) Oleg Butovsky et al. JOURNAL OF CLINICAL INVESTIGATION
- Innate immunity in the central nervous system
- (2012) Richard M. Ransohoff et al. JOURNAL OF CLINICAL INVESTIGATION
- Janus-like opposing roles of CD47 in autoimmune brain inflammation in humans and mice
- (2012) May H. Han et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Activation of Invariant NKT Cells in Early Phase of Experimental Autoimmune Encephalomyelitis Results in Differentiation of Ly6Chi Inflammatory Monocyte to M2 Macrophages and Improved Outcome
- (2012) L. Denney et al. JOURNAL OF IMMUNOLOGY
- Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation
- (2012) Jack van Horssen et al. Journal of Neuroinflammation
- Harnessing monocyte-derived macrophages to control central nervous system pathologies: no longer ‘if’ but ‘how’
- (2012) Ravid Shechter et al. JOURNAL OF PATHOLOGY
- T cells become licensed in the lung to enter the central nervous system
- (2012) Francesca Odoardi et al. NATURE
- Primary oligodendrocyte death does not elicit anti-CNS immunity
- (2012) Giuseppe Locatelli et al. NATURE NEUROSCIENCE
- B cells and antibodies in multiple sclerosis pathogenesis and therapy
- (2012) Markus Krumbholz et al. Nature Reviews Neurology
- Will the real multiple sclerosis please stand up?
- (2012) Peter K. Stys et al. NATURE REVIEWS NEUROSCIENCE
- Myelin-Derived Lipids Modulate Macrophage Activity by Liver X Receptor Activation
- (2012) Jeroen F. J. Bogie et al. PLoS One
- Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation
- (2012) H. Qin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- C3-dependent mechanism of microglial priming relevant to multiple sclerosis
- (2012) V. Ramaglia et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells
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- (2011) Emily M. Johansson et al. JOURNAL OF NEUROSCIENCE RESEARCH
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- (2011) Kerstin Berer et al. NATURE
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- (2011) Laura Codarri et al. NATURE IMMUNOLOGY
- The encephalitogenicity of TH17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF
- (2011) Mohamed El-Behi et al. NATURE IMMUNOLOGY
- A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis
- (2011) Ivana Nikić et al. NATURE MEDICINE
- Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool
- (2011) Bahareh Ajami et al. NATURE NEUROSCIENCE
- Inflammatory Cortical Demyelination in Early Multiple Sclerosis
- (2011) Claudia F. Lucchinetti et al. NEW ENGLAND JOURNAL OF MEDICINE
- Multiple Sclerosis is Not a Disease of the Immune System
- (2011) Angelique P. Corthals QUARTERLY REVIEW OF BIOLOGY
- Macrophages recruited via CCR2 produce insulin-like growth factor-1 to repair acute skeletal muscle injury
- (2010) Haiyan Lu et al. FASEB JOURNAL
- Microglia: Proliferation and activation driven by the P2X7 receptor
- (2010) Mastura Monif et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
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- (2010) Marloes van Zwam et al. JOURNAL OF NEUROIMMUNOLOGY
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- (2010) Holly R. Chinnery et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- The myeloid cells of the central nervous system parenchyma
- (2010) Richard M. Ransohoff et al. NATURE
- CD169+ macrophages present lipid antigens to mediate early activation of iNKT cells in lymph nodes
- (2010) Patricia Barral et al. NATURE IMMUNOLOGY
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- (2010) Eugene D Ponomarev et al. NATURE MEDICINE
- Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease
- (2010) Martin Fuhrmann et al. NATURE NEUROSCIENCE
- Selective Chemokine Receptor Usage by Central Nervous System Myeloid Cells in CCR2-Red Fluorescent Protein Knock-In Mice
- (2010) Noah Saederup et al. PLoS One
- Choroid plexus: biology and pathology
- (2009) Hartwig Wolburg et al. ACTA NEUROPATHOLOGICA
- Microglia: biology and pathology
- (2009) Manuel B. Graeber et al. ACTA NEUROPATHOLOGICA
- Multiple sclerosis: Distribution of inflammatory cells in newly forming lesions
- (2009) Andrew P. D. Henderson et al. ANNALS OF NEUROLOGY
- Blood Monocytes: Development, Heterogeneity, and Relationship with Dendritic Cells
- (2009) Cedric Auffray et al. Annual Review of Immunology
- Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease
- (2009) I. L. King et al. BLOOD
- Comparison of gene expression profiles between human and mouse monocyte subsets
- (2009) M. A. Ingersoll et al. BLOOD
- CCR2+Ly-6Chi monocytes are crucial for the effector phase of autoimmunity in the central nervous system
- (2009) Alexander Mildner et al. BRAIN
- Impact of human myelin on the maturation and function of human monocyte-derived dendritic cells
- (2009) Viktoria Gredler et al. CLINICAL IMMUNOLOGY
- Apoptotic Cells Promote Their Own Clearance and Immune Tolerance through Activation of the Nuclear Receptor LXR
- (2009) Noelia A-Gonzalez et al. IMMUNITY
- The surface-exposed chaperone, Hsp60, is an agonist of the microglial TREM2 receptor
- (2009) Luisa Stefano et al. JOURNAL OF NEUROCHEMISTRY
- Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions
- (2009) Ingo Bartholomäus et al. NATURE
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- (2009) Philip L De Jager et al. NATURE GENETICS
- C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE
- (2009) Andrea Reboldi et al. NATURE IMMUNOLOGY
- Gaining entry to an uninflamed brain
- (2009) Robert C Axtell et al. NATURE IMMUNOLOGY
- Structure and function of the blood–brain barrier
- (2009) N. Joan Abbott et al. NEUROBIOLOGY OF DISEASE
- Restoring immune suppression in the multiple sclerosis brain
- (2009) Nathalie Koning et al. PROGRESS IN NEUROBIOLOGY
- Identification of Splenic Reservoir Monocytes and Their Deployment to Inflammatory Sites
- (2009) F. K. Swirski et al. SCIENCE
- Infiltrating Blood-Derived Macrophages Are Vital Cells Playing an Anti-inflammatory Role in Recovery from Spinal Cord Injury in Mice
- (2009) Ravid Shechter et al. PLOS MEDICINE
- Localizing central nervous system immune surveillance: Meningeal antigen-presenting cells activate T cells during experimental autoimmune encephalomyelitis
- (2008) Pia Kivisäkk et al. ANNALS OF NEUROLOGY
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- (2008) Laura Piccio et al. BRAIN
- Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors
- (2008) Cynthia Hong et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Distinct and Nonredundant In Vivo Functions of IFNAR on Myeloid Cells Limit Autoimmunity in the Central Nervous System
- (2008) Marco Prinz et al. IMMUNITY
- ICAM-5—A novel two-facetted adhesion molecule in the mammalian brain
- (2008) Carl G. Gahmberg et al. IMMUNOLOGY LETTERS
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- (2008) Daniel R. Getts et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2008) Marloes van Zwam et al. JOURNAL OF MOLECULAR MEDICINE-JMM
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- (2008) Marco Vercellino et al. JOURNAL OF NEUROIMMUNOLOGY
- Abundant extracellular myelin in the meninges of patients with multiple sclerosis
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- Monocyte chemoattractant protein-1 in the choroid plexus: A potential link between vascular pro-inflammatory mediators and the CNS during peripheral tissue inflammation
- (2008) K. Mitchell et al. NEUROSCIENCE
- CD73 is required for efficient entry of lymphocytes into the central nervous system during experimental autoimmune encephalomyelitis
- (2008) J. H. Mills et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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