Fingolimod modulates microglial activation to augment markers of remyelination

Fingolimod (FTY720) Enhances Remyelination Following Demyelination of Organotypic Cerebellar Slices

(2010) Veronique E. Miron et al.   AMERICAN JOURNAL OF PATHOLOGY

Overcoming remyelination failure in multiple sclerosis and other myelin disorders

(2010) Stephen P.J. Fancy et al.   EXPERIMENTAL NEUROLOGY

Quantitative determination of BAF312, a S1P-R modulator, in human urine by LC–MS/MS: Prevention and recovery of lost analyte due to container surface adsorption

(2010) Wenkui Li et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Neuroprotection, regeneration and immunomodulation: broadening the therapeutic repertoire in multiple sclerosis

(2010) Orhan Aktas et al.   TRENDS IN NEUROSCIENCES

Promotion of central nervous system remyelination by induced differentiation of oligodendrocyte precursor cells

(2009) Sha Mi et al.   ANNALS OF NEUROLOGY

Sphingosine 1-Phosphate Receptor Signaling

(2009) Hugh Rosen et al.   Annual Review of Biochemistry

The immunomodulatory sphingosine 1-phosphate analog FTY720 reduces lesion size and improves neurological outcome in a mouse model of cerebral ischemia

(2009) Bozena Czech et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Anin vitromodel for de- and remyelination using lysophosphatidyl choline in rodent whole brain spheroid cultures

(2009) E. J. F. Vereyken et al.   GLIA

Lysophosphatidylcholine induces glial cell activation: Role of rho kinase

(2009) Abdullah Md. Sheikh et al.   GLIA

FTY720 ameliorates MOG-induced experimental autoimmune encephalomyelitis by suppressing both cellular and humoral immune responses

(2009) Dimitrios Papadopoulos et al.   JOURNAL OF NEUROSCIENCE RESEARCH

What Is the Optimal Value of the g-Ratio for Myelinated Fibers in the Rat CNS? A Theoretical Approach

(2009) Taylor Chomiak et al.   PLoS One

Cyclical and Dose-Dependent Responses of Adult Human Mature Oligodendrocytes to Fingolimod

(2008) Veronique E. Miron et al.   AMERICAN JOURNAL OF PATHOLOGY

FTY720 Rescue Therapy in the Dark Agouti Rat Model of Experimental Autoimmune Encephalomyelitis: Expression of Central Nervous System Genes and Reversal of Blood-Brain-Barrier Damage

(2008) Carolyn A. Foster et al.   BRAIN PATHOLOGY

Central nervous system effects of current and emerging multiple sclerosis-directed immuno-therapies

(2008) Jack P. Antel et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Myelinated, synapsing cultures of murine spinal cord - validation as anin vitromodel of the central nervous system

(2008) C. E. Thomson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

FTY720 modulates human oligodendrocyte progenitor process extension and survival

(2007) Veronique E. Miron et al.   ANNALS OF NEUROLOGY

Early attenuation of lesional interleukin-16 up-regulation by dexamethasone and FTY720 in experimental traumatic brain injury

(2007) Z. Zhang et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY