Role of NK cells in immunotherapy and virotherapy of solid tumors

Redistribution, Hyperproliferation, Activation of Natural Killer Cells and CD8 T Cells, and Cytokine Production During First-in-Human Clinical Trial of Recombinant Human Interleukin-15 in Patients With Cancer

(2015) Kevin C. Conlon et al.   JOURNAL OF CLINICAL ONCOLOGY

CD160 is essential for NK-mediated IFN-γ production

(2015) Tony C. Tu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The brave new world of innate lymphoid cells

(2015) Gérard Eberl et al.   NATURE IMMUNOLOGY

Advantages and applications of CAR-expressing natural killer cells

(2015) Wolfgang Glienke et al.   Frontiers in Pharmacology

Impact of multiplicity of functional KIR-HLA compound genotypes on hepatocellular carcinoma

(2015) Naoki Tanimine et al.   OncoImmunology

CXCL10-induced migration of adoptively transferred human natural killer cells toward solid tumors causes regression of tumor growth in vivo

(2014) Erik Wennerberg et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Metalloprotease-Mediated Tumor Cell Shedding of B7-H6, the Ligand of the Natural Killer Cell-Activating Receptor NKp30

(2014) E. Schlecker et al.   CANCER RESEARCH

Safety and Efficacy of VCN-01, an Oncolytic Adenovirus Combining Fiber HSG-Binding Domain Replacement with RGD and Hyaluronidase Expression

(2014) A. Rodriguez-Garcia et al.   CLINICAL CANCER RESEARCH

TLR activation of tumor-associated macrophages from ovarian cancer patients triggers cytolytic activity of NK cells

(2014) Francesca Bellora et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Effect of tumor cells and tumor microenvironment on NK-cell function

(2014) Massimo Vitale et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Cytokine therapy reverses NK cell anergy in MHC-deficient tumors

(2014) Michele Ardolino et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage Migration Inhibitory Factor Contributes to the Immune Escape of Ovarian Cancer by Down-Regulating NKG2D

(2014) M. Krockenberger et al.   JOURNAL OF IMMUNOLOGY

CD56brightPerforinlow Noncytotoxic Human NK Cells Are Abundant in Both Healthy and Neoplastic Solid Tissues and Recirculate to Secondary Lymphoid Organs via Afferent Lymph

(2014) P. Carrega et al.   JOURNAL OF IMMUNOLOGY

Maraba MG1 Virus Enhances Natural Killer Cell Function via Conventional Dendritic Cells to Reduce Postoperative Metastatic Disease

(2014) Jiqing Zhang et al.   MOLECULAR THERAPY

Glioma virus therapies between bench and bedside

(2014) J. K. Kaufmann et al.   NEURO-ONCOLOGY

Modulation of CD112 by the alphaherpesvirus gD protein suppresses DNAM-1–dependent NK cell-mediated lysis of infected cells

(2014) Korneel Grauwet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of human natural killer cells and other innate lymphoid cells

(2014) Elisa Montaldo et al.   SEMINARS IN IMMUNOLOGY

Clinical utility of natural killer cells in cancer therapy and transplantation

(2014) David A. Knorr et al.   SEMINARS IN IMMUNOLOGY

Oncolytic herpes simplex virus-based strategies: toward a breakthrough in glioblastoma therapy

(2014) Jianfang Ning et al.   Frontiers in Microbiology

Oncolytic Viruses and Their Application to Cancer Immunotherapy

(2014) E. A. Chiocca et al.   Cancer Immunology Research

Baseline and Dynamic Expression of Activating NK Cell Receptors in the Control of Chronic Viral Infections: The Paradigm of HIV-1 and HCV

(2014) Francesco Marras et al.   Frontiers in Immunology

The DNA Damage Response: A Common Pathway in the Regulation of NKG2D and DNAM-1 Ligand Expression in Normal, Infected, and Cancer Cells

(2014) Cristina Cerboni et al.   Frontiers in Immunology

Trial Watch:

(2014) Jonathan Pol et al.   OncoImmunology

Oncolytic Viruses as Anticancer Vaccines

(2014) Norman Woller et al.   Frontiers in Oncology

Regulation of Ligands for the NKG2D Activating Receptor

(2013) David H. Raulet et al.   Annual Review of Immunology

Identification of a cellular ligand for the natural cytotoxicity receptor NKp44

(2013) F. Baychelier et al.   BLOOD

Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies

(2013) H. E. Kohrt et al.   BLOOD

Soluble ligands for NK cell receptors promote evasion of chronic lymphocytic leukemia cells from NK cell anti-tumor activity

(2013) K. S. Reiners et al.   BLOOD

NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs

(2013) V. Beziat et al.   BLOOD

Advantages and clinical applications of natural killer cells in cancer immunotherapy

(2013) Erik Ames et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Mature Cytotoxic CD56bright/CD16+ Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma

(2013) M. Messaoudene et al.   CANCER RESEARCH

Immune Infiltrates Are Prognostic Factors in Localized Gastrointestinal Stromal Tumors

(2013) S. Rusakiewicz et al.   CANCER RESEARCH

Characteristics and Clinical Impacts of the Immune Environments in Colorectal and Renal Cell Carcinoma Lung Metastases: Influence of Tumor Origin

(2013) R. Remark et al.   CLINICAL CANCER RESEARCH

Hypoxia downregulates the expression of activating receptors involved in NK-cell-mediated target cell killing without affecting ADCC

(2013) Mirna Balsamo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The interaction between CD300a and phosphatidylserine inhibits tumor cell killing by NK cells

(2013) Dikla Lankry et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Adaptive reconfiguration of the human NK-cell compartment in response to cytomegalovirus: A different perspective of the host-pathogen interaction

(2013) Aura Muntasell et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Soluble ligands for the NKG2D receptor are released during HIV-1 infection and impair NKG2D expression and cytotoxicity of NK cells

(2013) Giulia Matusali et al.   FASEB JOURNAL

Efficacy of oncolytic adenovirus expressing suicide genes and interleukin-12 in preclinical model of prostate cancer

(2013) S O Freytag et al.   GENE THERAPY

Sorafenib perpetuates cellular anticancer effector functions by modulating the crosstalk between macrophages and natural killer cells

(2013) Martin Franz Sprinzl et al.   HEPATOLOGY

Innate immune responses in hepatitis C virus-exposed healthcare workers who do not develop acute infection

(2013) Jens Martin Werner et al.   HEPATOLOGY

DNAM-1 control of natural killer cells functions through nectin and nectin-like proteins

(2013) Lucas Ferrari de Andrade et al.   IMMUNOLOGY AND CELL BIOLOGY

Natural killer cell deficiency

(2013) Jordan S. Orange   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2

(2013) Jonathan Sitrin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hepatitis C Virus-Infected Cells Downregulate NKp30 and Inhibit Ex Vivo NK Cell Functions

(2013) K. A. Holder et al.   JOURNAL OF IMMUNOLOGY

Neuroblastoma-Derived TGF- 1 Modulates the Chemokine Receptor Repertoire of Human Resting NK Cells

(2013) R. Castriconi et al.   JOURNAL OF IMMUNOLOGY

Colorectal carcinoma-derived fibroblasts modulate natural killer cell phenotype and antitumor cytotoxicity

(2013) Tuanjie Li et al.   MEDICAL ONCOLOGY

New viruses for cancer therapy: meeting clinical needs

(2013) Tanner S. Miest et al.   NATURE REVIEWS MICROBIOLOGY

Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia

(2013) Stephan A. Grupp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Myxoma Virus Infection Promotes NK Lysis of Malignant Gliomas In Vitro and In Vivo

(2013) Henry Ogbomo et al.   PLoS One

Natural killer cells in HIV controller patients express an activated effector phenotype and do not up-regulate NKp44 on IL-2 stimulation

(2013) F. Marras et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CD19-Targeted T Cells Rapidly Induce Molecular Remissions in Adults with Chemotherapy-Refractory Acute Lymphoblastic Leukemia

(2013) R. J. Brentjens et al.   Science Translational Medicine

Novel immune modulators used in hematology: impact on NK cells

(2013) Stephanie Krieg et al.   Frontiers in Immunology

Impact of HCMV Infection on NK Cell Development and Function after HSCT

(2013) Mariella Della Chiesa et al.   Frontiers in Immunology

Cellular and molecular basis of haploidentical hematopoietic stem cell transplantation in the successful treatment of high-risk leukemias: role of alloreactive NK cells

(2013) Franco Locatelli et al.   Frontiers in Immunology

The Critical Role of the Tumor Microenvironment in Shaping Natural Killer Cell-Mediated Anti-Tumor Immunity

(2013) Joanna Baginska et al.   Frontiers in Immunology

Arming NK cells with enhanced antitumor activity

(2013) Pranav Oberoi et al.   OncoImmunology

Phase I/IIa study of intratumoral/intracerebral or intravenous/intracerebral administration of Parvovirus H-1 (ParvOryx) in patients with progressive primary or recurrent glioblastoma multiforme: ParvOryx01 protocol

(2012) Karsten Geletneky et al.   BMC CANCER

The role of natural killer cells in combinatorial anti-cancer therapy using Sindbis viral vectors and irinotecan

(2012) T Granot et al.   CANCER GENE THERAPY

Antitumoral activity of parvovirus-mediated IL-2 and MCP-3/CCL7 delivery into human pancreatic cancer: implication of leucocyte recruitment

(2012) Sebastian Dempe et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Expression of IL-15 in NK cells results in rapid enrichment and selective cytotoxicity of gene-modified effectors that carry a tumor-specific antigen receptor

(2012) Christiane Sahm et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Oncolytic Virus and Anti-4-1BB Combination Therapy Elicits Strong Antitumor Immunity against Established Cancer

(2012) L. B. John et al.   CANCER RESEARCH

Melanoma Cells Inhibit Natural Killer Cell Function by Modulating the Expression of Activating Receptors and Cytolytic Activity

(2012) G. Pietra et al.   CANCER RESEARCH

Melanoma cells become resistant to NK-cell-mediated killing when exposed to NK-cell numbers compatible with NK-cell infiltration in the tumor

(2012) Mirna Balsamo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Sustained effector function of IL-12/15/18–preactivated NK cells against established tumors

(2012) Jing Ni et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Extracellular matrix constituents interfere with Newcastle disease virus spread in solid tissue and diminish its potential oncolytic activity

(2012) B. Yaacov et al.   JOURNAL OF GENERAL VIROLOGY

A First in Human Phase 1 Study of CG0070, a GM-CSF Expressing Oncolytic Adenovirus, for the Treatment of Nonmuscle Invasive Bladder Cancer

(2012) James M. Burke et al.   JOURNAL OF UROLOGY

The Histone Deacetylase Inhibitor Valproic Acid Lessens NK Cell Action against Oncolytic Virus-Infected Glioblastoma Cells by Inhibition of STAT5/T-BET Signaling and Generation of Gamma Interferon

(2012) Christopher A. Alvarez-Breckenridge et al.   JOURNAL OF VIROLOGY

Kaposi's Sarcoma-Associated Herpesvirus ORF54/dUTPase Downregulates a Ligand for the NK Activating Receptor NKp44

(2012) Alexis Spain Madrid et al.   JOURNAL OF VIROLOGY

Evasion from NK cell-mediated immune responses by HIV-1

(2012) Stephanie Jost et al.   MICROBES AND INFECTION

ORFV: A Novel Oncolytic and Immune Stimulating Parapoxvirus Therapeutic

(2012) Julia L Rintoul et al.   MOLECULAR THERAPY

Harnessing Oncolytic Virus-mediated Antitumor Immunity in an Infected Cell Vaccine

(2012) Chantal G Lemay et al.   MOLECULAR THERAPY

An Oncolytic Adenovirus Enhanced for Toll-like Receptor 9 Stimulation Increases Antitumor Immune Responses and Tumor Clearance

(2012) Vincenzo Cerullo et al.   MOLECULAR THERAPY

Phase II Trial of Intravenous Administration of Reolysin® (Reovirus Serotype-3-dearing Strain) in Patients with Metastatic Melanoma

(2012) Evanthia Galanis et al.   MOLECULAR THERAPY

NK cells impede glioblastoma virotherapy through NKp30 and NKp46 natural cytotoxicity receptors

(2012) Christopher A Alvarez-Breckenridge et al.   NATURE MEDICINE

Human Herpesvirus 8 (HHV8) Sequentially Shapes the NK Cell Repertoire during the Course of Asymptomatic Infection and Kaposi Sarcoma

(2012) Stéphanie Dupuy et al.   PLoS Pathogens

Trial Watch

(2012) Erika Vacchelli et al.   OncoImmunology

Natural Innate and Adaptive Immunity to Cancer

(2011) Matthew D. Vesely et al.   Annual Review of Immunology

IPH2101, a novel anti-inhibitory KIR antibody, and lenalidomide combine to enhance the natural killer cell versus multiple myeloma effect

(2011) D. M. Benson et al.   BLOOD

Hepatocellular carcinoma-associated fibroblasts trigger NK cell dysfunction via PGE2 and IDO

(2011) Tuanjie Li et al.   CANCER LETTERS

Profound Coordinated Alterations of Intratumoral NK Cell Phenotype and Function in Lung Carcinoma

(2011) S. Platonova et al.   CANCER RESEARCH

Adoptive Transfer of Autologous Natural Killer Cells Leads to High Levels of Circulating Natural Killer Cells but Does Not Mediate Tumor Regression

(2011) M. R. Parkhurst et al.   CLINICAL CANCER RESEARCH

Anti-EGFR Antibody Cetuximab Enhances the Cytolytic Activity of Natural Killer Cells toward Osteosarcoma

(2011) J. H. W. Pahl et al.   CLINICAL CANCER RESEARCH

Natural Killer Cells are Scarce in Colorectal Carcinoma Tissue Despite High Levels of Chemokines and Cytokines

(2011) N. Halama et al.   CLINICAL CANCER RESEARCH

Activating NK cell receptor expression/function (NKp30, NKp46, DNAM-1) during chronic viraemic HCV infection is associated with the outcome of combined treatment

(2011) Federica Bozzano et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Oncolytic adenovirus co-expressing IL-12 and IL-18 improves tumor-specific immunity via differentiation of T cells expressing IL-12Rβ2 or IL-18Rα

(2011) I-K Choi et al.   GENE THERAPY

Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity

(2011) Emilie Mamessier et al.   JOURNAL OF CLINICAL INVESTIGATION

Proliferating Cell Nuclear Antigen Is a Novel Inhibitory Ligand for the Natural Cytotoxicity Receptor NKp44

(2011) B. Rosental et al.   JOURNAL OF IMMUNOLOGY

Regulation of Immune Responses by Prostaglandin E2

(2011) P. Kalinski   JOURNAL OF IMMUNOLOGY

Natural Killer Cells and Solid Tumors

(2011) Ana Stojanovic et al.   Journal of Innate Immunity

Oncolytic Specificity of Newcastle Disease Virus Is Mediated by Selectivity for Apoptosis-Resistant Cells

(2011) M. Mansour et al.   JOURNAL OF VIROLOGY

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors

(2011) Nicolas F Delahaye et al.   NATURE MEDICINE

Chimeric Antigen Receptor–Modified T Cells in Chronic Lymphoid Leukemia

(2011) David L. Porter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Activation of Cytotoxic and Regulatory Functions of NK Cells by Sindbis Viral Vectors

(2011) Tomer Granot et al.   PLoS One

Expansion of a unique CD57+NKG2Chi natural killer cell subset during acute human cytomegalovirus infection

(2011) S. Lopez-Verges et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate or Adaptive Immunity? The Example of Natural Killer Cells

(2011) E. Vivier et al.   SCIENCE

Origin, phenotype and function of human natural killer cells in pregnancy

(2011) Paola Vacca et al.   TRENDS IN IMMUNOLOGY

Unconventional Repertoire Profile Is Imprinted during Acute Chikungunya Infection for Natural Killer Cells Polarization toward Cytotoxicity

(2011) Caroline Petitdemange et al.   PLoS Pathogens

Modulation of NKp30- and NKp46-Mediated Natural Killer Cell Responses by Poxviral Hemagglutinin

(2011) Mostafa Jarahian et al.   PLoS Pathogens

Dissecting CD56dim human NK cells

(2010) L. Moretta   BLOOD

CD62L expression identifies a unique subset of polyfunctional CD56dim NK cells

(2010) K. Juelke et al.   BLOOD

NKp46 and DNAM-1 NK-cell receptors drive the response to human cytomegalovirus-infected myeloid dendritic cells overcoming viral immune evasion strategies

(2010) G. Magri et al.   BLOOD

Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education

(2010) N. K. Bjorkstrom et al.   BLOOD

CD57 defines a functionally distinct population of mature NK cells in the human CD56dimCD16+ NK-cell subset

(2010) S. Lopez-Verges et al.   BLOOD

A phase I trial of adoptive transfer of allogeneic natural killer cells in patients with advanced non-small cell lung cancer

(2010) Eleni G. Iliopoulou et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Modulation of natural killer cell activity by viruses

(2010) Vanda Juranić Lisnić et al.   CURRENT OPINION IN MICROBIOLOGY

Impact of tumor microenvironment on oncolytic viral therapy

(2010) Jeffrey Wojton et al.   CYTOKINE & GROWTH FACTOR REVIEWS

A phase II study of allogeneic natural killer cell therapy to treat patients with recurrent ovarian and breast cancer

(2010) Melissa A. Geller et al.   CYTOTHERAPY

Activation of Natural Killer Cells During Acute Infection With Hepatitis C Virus

(2010) Barbara Amadei et al.   GASTROENTEROLOGY

Increased natural killer cell cytotoxicity and NKp30 expression protects against hepatitis C virus infection in high-risk individuals and inhibits replication in vitro

(2010) Lucy Golden-Mason et al.   HEPATOLOGY

Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus

(2010) Niklas K. Björkström et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human cytomegalovirus UL141 promotes efficient downregulation of the natural killer cell activating ligand CD112

(2010) V. Prod'homme et al.   JOURNAL OF GENERAL VIROLOGY

Tumor Immunoediting by NKp46

(2010) M. Elboim et al.   JOURNAL OF IMMUNOLOGY

MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells

(2010) Jennifer AA Gubbels et al.   Molecular Cancer

Hyaluronidase Expression by an Oncolytic Adenovirus Enhances Its Intratumoral Spread and Suppresses Tumor Growth

(2010) Sonia Guedan et al.   MOLECULAR THERAPY

Vesicular Stomatitis Virus-induced Immune Suppressor Cells Generate Antagonism Between Intratumoral Oncolytic Virus and Cyclophosphamide

(2010) Candice Willmon et al.   MOLECULAR THERAPY

Revisiting human natural killer cell subset function revealed cytolytic CD56dimCD16+ NK cells as rapid producers of abundant IFN-  on activation

(2010) A. De Maria et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New views on natural killer cell-based immunotherapy for melanoma treatment

(2010) Shannon Burke et al.   TRENDS IN IMMUNOLOGY

HIV escape from natural killer cytotoxicity: nef inhibits NKp44L expression on CD4+ T cells

(2009) Hugues Fausther-Bovendo et al.   AIDS

Preclinical characterization of 1-7F9, a novel human anti-KIR receptor therapeutic antibody that augments natural killer-mediated killing of tumor cells

(2009) F. Romagne et al.   BLOOD

HIV-1 Vpr up-regulates expression of ligands for the activating NKG2D receptor and promotes NK cell-mediated killing

(2009) J. Richard et al.   BLOOD

A phase 2, randomized study of SB-485232, rhIL-18, in patients with previously untreated metastatic melanoma

(2009) Ahmad A. Tarhini et al.   CANCER

Functions of γC cytokines in immune homeostasis: Current and potential clinical applications

(2009) Willem W. Overwijk et al.   CLINICAL IMMUNOLOGY

Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor

(2009) Bastian Hoechst et al.   HEPATOLOGY

The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans

(2009) Cameron S. Brandt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Hepatitis C virions subvert natural killer cell activation to generate a cytokine environment permissive for infection

(2009) Stefania Crotta et al.   JOURNAL OF HEPATOLOGY

Reciprocal Human Dendritic Cell-Natural Killer Cell Interactions Induce Antitumor Activity Following Tumor Cell Infection by Oncolytic Reovirus

(2009) R. J. Prestwich et al.   JOURNAL OF IMMUNOLOGY

Sustained and NK/CD4+ T Cell-Dependent Efficient Prevention of Lung Metastasis Induced by Dendritic Cells Harboring Recombinant Sendai Virus

(2009) A. Komaru et al.   JOURNAL OF IMMUNOLOGY

NKp44 Receptor Mediates Interaction of the Envelope Glycoproteins from the West Nile and Dengue Viruses with NK Cells

(2009) O. Hershkovitz et al.   JOURNAL OF IMMUNOLOGY

Natural Cytotoxicity Receptors NKp30, NKp44 and NKp46 Bind to Different Heparan Sulfate/Heparin Sequences

(2009) Marie-Lyn Hecht et al.   JOURNAL OF PROTEOME RESEARCH

Activation of Natural Killer Cells by Newcastle Disease Virus Hemagglutinin-Neuraminidase

(2009) M. Jarahian et al.   JOURNAL OF VIROLOGY

Melanoma-associated fibroblasts modulate NK cell phenotype and antitumor cytotoxicity

(2009) M. Balsamo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Herpes Simplex Virus Infection Downmodulates NKG2D Ligand Expression

(2009) D. Schepis et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

IFN-α-mediated increase in cytolytic activity of maturing NK cell upon exposure to HSV-infected myelomonocytes

(2008) Paola Costa et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Natural killer cell function is intact after direct exposure to infectious hepatitis C virions

(2008) Joo Chun Yoon et al.   HEPATOLOGY

Treg Depletion–enhanced IL-2 Treatment Facilitates Therapy of Established Tumors Using Systemically Delivered Oncolytic Virus

(2008) Timothy Kottke et al.   MOLECULAR THERAPY

Use of Biological Therapy to Enhance Both Virotherapy and Adoptive T-Cell Therapy for Cancer

(2008) Timothy Kottke et al.   MOLECULAR THERAPY

Phase Ib Trial of Mutant Herpes Simplex Virus G207 Inoculated Pre-and Post-tumor Resection for Recurrent GBM

(2008) James M Markert et al.   MOLECULAR THERAPY

Natural killer cell–directed therapies: moving from unexpected results to successful strategies

(2008) Magali Terme et al.   NATURE IMMUNOLOGY

The tumor microenvironment and its role in promoting tumor growth

(2008) T L Whiteside   ONCOGENE

Directed Evolution Generates a Novel Oncolytic Virus for the Treatment of Colon Cancer

(2008) Irene Kuhn et al.   PLoS One

Exponential Enhancement of Oncolytic Vesicular Stomatitis Virus Potency by Vector-mediated Suppression of Inflammatory Responses In Vivo

(2007) Jennifer Altomonte et al.   MOLECULAR THERAPY