DNAM-1 control of natural killer cells functions through nectin and nectin-like proteins

Controlling Natural Killer Cell Responses: Integration of Signals for Activation and Inhibition

(2013) Eric O. Long et al.   Annual Review of Immunology

ATM-dependent spontaneous regression of early E -myc-induced murine B-cell leukemia depends on natural killer and T cells

(2013) J. L. Croxford et al.   BLOOD

Molecular mechanisms of natural killer cell activation in response to cellular stress

(2013) C J Chan et al.   CELL DEATH AND DIFFERENTIATION

Mouse TIGIT inhibits NK-cell cytotoxicity upon interaction with PVR

(2013) Noa Stanietsky et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulatory T cells control NK cells in an insulitic lesion by depriving them of IL-2

(2013) Jonathan Sitrin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The human immunodeficiency virus type 1 Vpr protein upregulates PVR via activation of the ATR-mediated DNA damage response pathway

(2013) L. Vassena et al.   JOURNAL OF GENERAL VIROLOGY

The CD226/CD155 Interaction Regulates the Proinflammatory (Th1/Th17)/Anti-Inflammatory (Th2) Balance in Humans

(2013) E. Lozano et al.   JOURNAL OF IMMUNOLOGY

Toll-Like Receptor Ligands Induce Expression of the Costimulatory Molecule CD155 on Antigen-Presenting Cells

(2013) Neha Kamran et al.   PLoS One

Recruitment of Grb2 and SHIP1 by the ITT-like motif of TIGIT suppresses granule polarization and cytotoxicity of NK cells

(2012) S Liu et al.   CELL DEATH AND DIFFERENTIATION

Receptors that interact with nectin and nectin-like proteins in the immunosurveillance and immunotherapy of cancer

(2012) Christopher J Chan et al.   CURRENT OPINION IN IMMUNOLOGY

CD226 Gly307Ser association with multiple autoimmune diseases: A meta-analysis

(2012) Zhi-Xin Qiu et al.   HUMAN IMMUNOLOGY

The TIGIT/CD226 Axis Regulates Human T Cell Function

(2012) E. Lozano et al.   JOURNAL OF IMMUNOLOGY

The Human Immunodeficiency Virus Type 1 Nef and Vpu Proteins Downregulate the Natural Killer Cell-Activating Ligand PVR

(2012) Giulia Matusali et al.   JOURNAL OF VIROLOGY

Association between the CD226 rs763361 polymorphism and susceptibility to autoimmune diseases: a meta-analysis

(2012) GG Song et al.   LUPUS

Complementary Phosphorylation Sites in the Adaptor Protein SLP-76 Promote Synergistic Activation of Natural Killer Cells

(2012) H. S. Kim et al.   Science Signaling

CD8 T cell defect of TNF-α and IL-2 in DNAM-1 deficient mice delays clearance in vivo of a persistent virus infection

(2012) Megan J. Welch et al.   VIROLOGY

Natural killer cells expressing the KIR2DS1-activating receptor efficiently kill T-cell blasts and dendritic cells: implications in haploidentical HSCT

(2011) S. Sivori et al.   BLOOD

DNAM-1 ligand expression on Ag-stimulated T lymphocytes is mediated by ROS-dependent activation of DNA-damage response: relevance for NK-T cell interaction

(2011) M. Ardolino et al.   BLOOD

Vstm3 is a member of the CD28 family and an important modulator of T-cell function

(2011) Steven D. Levin et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Decreased expression of DNAM-1 on NK cells from acute myeloid leukemia patients

(2011) Beatriz Sanchez-Correa et al.   IMMUNOLOGY AND CELL BIOLOGY

Intranodal Interaction with Dendritic Cells Dynamically Regulates Surface Expression of the Co-stimulatory Receptor CD226 Protein on Murine T Cells

(2011) Sebastian Seth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity

(2011) Emilie Mamessier et al.   JOURNAL OF CLINICAL INVESTIGATION

Cutting Edge: TIGIT Has T Cell-Intrinsic Inhibitory Functions

(2011) N. Joller et al.   JOURNAL OF IMMUNOLOGY

Ipilimumab plus Dacarbazine for Previously Untreated Metastatic Melanoma

(2011) Caroline Robert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mobilization of natural killer cells inhibits development of collagen-induced arthritis

(2011) J. W. Leavenworth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NKp46 and DNAM-1 NK-cell receptors drive the response to human cytomegalovirus-infected myeloid dendritic cells overcoming viral immune evasion strategies

(2010) G. Magri et al.   BLOOD

NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects

(2010) J. A. Olson et al.   BLOOD

Loss of DNAM-1 contributes to CD8+T-cell exhaustion in chronic HIV-1 infection

(2010) Marina Cella et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Synergistic Signals for Natural Cytotoxicity Are Required to Overcome Inhibition by c-Cbl Ubiquitin Ligase

(2010) Hun Sik Kim et al.   IMMUNITY

Human cytomegalovirus UL141 promotes efficient downregulation of the natural killer cell activating ligand CD112

(2010) V. Prod'homme et al.   JOURNAL OF GENERAL VIROLOGY

Non-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases

(2010) A. K. Maiti et al.   RHEUMATOLOGY

Association of the CD226 single nucleotide polymorphism with systemic lupus erythematosus in the Chinese Han population

(2010) Y. Du et al.   TISSUE ANTIGENS

Regulation of human NK-cell cytokine and chemokine production by target cell recognition

(2009) C. Fauriat et al.   BLOOD

Natural killer cells in human autoimmunity

(2009) Malin Flodström-Tullberg et al.   CURRENT OPINION IN IMMUNOLOGY

A novel molecular interaction for the adhesion of follicular CD4 T cells to follicular DC

(2009) Kent S. Boles et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Novel association of the CD226 (DNAM-1) Gly307Ser polymorphism in Wegener's granulomatosis and confirmation for multiple sclerosis in German patients

(2009) S Wieczorek et al.   GENES AND IMMUNITY

NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo

(2009) Tadepally Lakshmikanth et al.   JOURNAL OF CLINICAL INVESTIGATION

Primary Human Tumor Cells Expressing CD155 Impair Tumor Targeting by Down-Regulating DNAM-1 on NK Cells

(2009) M. Carlsten et al.   JOURNAL OF IMMUNOLOGY

DNAM-1/CD155 Interactions Promote Cytokine and NK Cell-Mediated Suppression of Poorly Immunogenic Melanoma Metastases

(2009) C. J. Chan et al.   JOURNAL OF IMMUNOLOGY

Tissue-Specific Homing and Expansion of Donor NK Cells in Allogeneic Bone Marrow Transplantation

(2009) J. A. Olson et al.   JOURNAL OF IMMUNOLOGY

The interaction of TIGIT with PVR and PVRL2 inhibits human NK cell cytotoxicity

(2009) N. Stanietsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple ITAM-coupled NK-cell receptors engage the Bcl10/Malt1 complex via Carma1 for NF- B and MAPK activation to selectively control cytokine production

(2008) O. Gross et al.   BLOOD

ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype

(2008) A. Soriani et al.   BLOOD

CD96 Interaction with CD155 via Its First Ig-like Domain Is Modulated by Alternative Splicing or Mutations in Distal Ig-like Domains

(2008) Dorothee Meyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Accelerated tumor growth in mice deficient in DNAM-1 receptor

(2008) Akiko Iguchi-Manaka et al.   JOURNAL OF EXPERIMENTAL MEDICINE

DNAM-1 promotes activation of cytotoxic lymphocytes by nonprofessional antigen-presenting cells and tumors

(2008) Susan Gilfillan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NK cells recognize and lyse Ewing sarcoma cells through NKG2D and DNAM-1 receptor dependent pathways

(2008) Dirk H.J. Verhoeven et al.   MOLECULAR IMMUNOLOGY

Natural killer cell recognition of missing self

(2008) Klas Kärre   NATURE IMMUNOLOGY

The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells

(2008) Xin Yu et al.   NATURE IMMUNOLOGY

Up on the tightrope: natural killer cell activation and inhibition

(2008) Lewis L Lanier   NATURE IMMUNOLOGY

Functions of natural killer cells

(2008) Eric Vivier et al.   NATURE IMMUNOLOGY