Technologies for label-free separation of circulating tumor cells: from historical foundations to recent developments

Continual collection and re-separation of circulating tumor cells from blood using multi-stage multi-orifice flow fractionation

(2013) Hui-Sung Moon et al.   Biomicrofluidics

Antibody-independent isolation of circulating tumor cells by continuous-flow dielectrophoresis

(2013) Sangjo Shim et al.   Biomicrofluidics

Highly selective biomechanical separation of cancer cells from leukocytes using microfluidic ratchets and hydrodynamic concentrator

(2013) Bill K. Lin et al.   Biomicrofluidics

Label-free isolation of circulating tumor cells in microfluidic devices: Current research and perspectives

(2013) Igor Cima et al.   Biomicrofluidics

Rapid isolation of cancer cells using microfluidic deterministic lateral displacement structure

(2013) Zongbin Liu et al.   Biomicrofluidics

Complex Tumor Genomes Inferred from Single Circulating Tumor Cells by Array-CGH and Next-Generation Sequencing

(2013) E. Heitzer et al.   CANCER RESEARCH

High-purity and label-free isolation of circulating tumor cells (CTCs) in a microfluidic platform by using optically-induced-dielectrophoretic (ODEP) force

(2013) Song-Bin Huang et al.   LAB ON A CHIP

Enrichment, detection and clinical significance of circulating tumor cells

(2013) Sunil K. Arya et al.   LAB ON A CHIP

Microfluidic flow fractionation device for label-free isolation of circulating tumor cells (CTCs) from breast cancer patients

(2012) Kyung-A Hyun et al.   BIOSENSORS & BIOELECTRONICS

Evaluation of Circulating Tumor Cells and Circulating Tumor DNA in Non-Small Cell Lung Cancer: Association with Clinical Endpoints in a Phase II Clinical Trial of Pertuzumab and Erlotinib

(2012) E. A. Punnoose et al.   CLINICAL CANCER RESEARCH

Circulating Tumor Cells: Liquid Biopsy of Cancer

(2012) C. Alix-Panabieres et al.   CLINICAL CHEMISTRY

Correlations between the dielectric properties and exterior morphology of cells revealed by dielectrophoretic field-flow fractionation

(2012) Peter R. C. Gascoyne et al.   ELECTROPHORESIS

Microfluidics and Circulating Tumor Cells

(2012) Yi Dong et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

The Emerging Role of Circulating Tumor Cell Detection in Genitourinary Cancer

(2012) Alexander C. Small et al.   JOURNAL OF UROLOGY

Sorting cells by size, shape and deformability

(2012) Jason P. Beech et al.   LAB ON A CHIP

Cell separation based on size and deformability using microfluidic funnel ratchets

(2012) Sarah M. McFaul et al.   LAB ON A CHIP

Microsieve lab-chip device for rapid enumeration and fluorescence in situ hybridization of circulating tumor cells

(2012) Li Shi Lim et al.   LAB ON A CHIP

Double spiral microchannel for label-free tumor cell separation and enrichment

(2012) Jiashu Sun et al.   LAB ON A CHIP

Microfluidic micropipette aspiration for measuring the deformability of single cells

(2012) Quan Guo et al.   LAB ON A CHIP

Microfluidic approaches for cancer cell detection, characterization, and separation

(2012) Jian Chen et al.   LAB ON A CHIP

Microfluidic: An innovative tool for efficient cell sorting

(2012) Julien Autebert et al.   METHODS

High-definition imaging of circulating tumor cells and associated cellular events in non-small cell lung cancer patients: a longitudinal analysis

(2012) Jorge Nieva et al.   PHYSICAL BIOLOGY

Fluid biopsy in patients with metastatic prostate, pancreatic and breast cancers

(2012) Dena Marrinucci et al.   PHYSICAL BIOLOGY

Deterministic separation of cancer cells from blood at 10 mL/min

(2012) Kevin Loutherback et al.   AIP Advances

High-throughput size-based rare cell enrichment using microscale vortices

(2011) Soojung Claire Hur et al.   Biomicrofluidics

Mechanical Stiffness Grades Metastatic Potential in Patient Tumor Cells and in Cancer Cell Lines

(2011) V. Swaminathan et al.   CANCER RESEARCH

Circulating Tumor Cells in Breast Cancer: Detection Systems, Molecular Characterization, and Future Challenges

(2011) E. S. Lianidou et al.   CLINICAL CHEMISTRY

Interdigitated comb-like electrodes for continuous separation of malignant cells from blood using dielectrophoresis

(2011) Anas Alazzam et al.   ELECTROPHORESIS

Circulating tumor cells: advances in detection methods, biological issues, and clinical relevance

(2011) Yun-Fan Sun et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Circulating tumor cells: approaches to isolation and characterization

(2011) Min Yu et al.   JOURNAL OF CELL BIOLOGY

Continuous separation of breast cancer cells from blood samples using multi-orifice flow fractionation (MOFF) and dielectrophoresis (DEP)

(2011) Hui-Sung Moon et al.   LAB ON A CHIP

Chromatographic behaviour of single cells in a microchannel with dynamic geometry

(2011) Thomas Gerhardt et al.   LAB ON A CHIP

Pinched flow coupled shear-modulated inertial microfluidics for high-throughput rare blood cell separation

(2011) Ali Asgar S. Bhagat et al.   LAB ON A CHIP

Circulating tumor cell detection in advanced non-small cell lung cancer patients by multi-marker QPCR analysis

(2011) L.A. Devriese et al.   LUNG CANCER

Circulating Tumor Cells from Patients with Advanced Prostate and Breast Cancer Display Both Epithelial and Mesenchymal Markers

(2011) A. J. Armstrong et al.   MOLECULAR CANCER RESEARCH

FISH-based determination of HER2 status in circulating tumor cells isolated with the microfluidic CEE™ platform

(2011) Julie Ann Mayer et al.   Cancer Genetics

Label-free cell separation and sorting in microfluidic systems

(2010) Daniel R. Gossett et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Microsystems for the Capture of Low-Abundance Cells

(2010) Udara Dharmasiri et al.   Annual Review of Analytical Chemistry

3D microfilter device for viable circulating tumor cell (CTC) enrichment from blood

(2010) Siyang Zheng et al.   BIOMEDICAL MICRODEVICES

Versatile label free biochip for the detection of circulating tumor cells from peripheral blood in cancer patients

(2010) Swee Jin Tan et al.   BIOSENSORS & BIOELECTRONICS

Rare cell capture in microfluidic devices

(2010) Erica D. Pratt et al.   CHEMICAL ENGINEERING SCIENCE

Portable Filter-Based Microdevice for Detection and Characterization of Circulating Tumor Cells

(2010) H. K. Lin et al.   CLINICAL CANCER RESEARCH

Preoperative Circulating Tumor Cell Detection Using the Isolation by Size of Epithelial Tumor Cell Method for Patients with Lung Cancer Is a New Prognostic Biomarker

(2010) V. Hofman et al.   CLINICAL CANCER RESEARCH

Application of a Filtration- and Isolation-by-Size Technique for the Detection of Circulating Tumor Cells in Cutaneous Melanoma

(2010) Vincenzo De Giorgi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Deformability considerations in filtration of biological cells

(2010) Jason S. Kuo et al.   LAB ON A CHIP

Microfluidics for cell separation

(2010) Ali Asgar S. Bhagat et al.   MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING

Molecular mechanisms of metastasis in breast cancer—clinical applications

(2010) Michal Mego et al.   Nature Reviews Clinical Oncology

Cytomorphology of Circulating Colorectal Tumor Cells: A Small Case Series

(2010) Dena Marrinucci et al.   Journal of Oncology

Efficient microfluidic particle separation arrays

(2009) David W. Inglis   APPLIED PHYSICS LETTERS

Fluorescence In situ Hybridization Analysis of Circulating Tumor Cells in Metastatic Prostate Cancer

(2009) M. A. Leversha et al.   CLINICAL CANCER RESEARCH

Isolation of rare cells from cell mixtures by dielectrophoresis

(2009) Peter R. C. Gascoyne et al.   ELECTROPHORESIS

Inertial microfluidics

(2009) Dino Di Carlo   LAB ON A CHIP

Circulating Tumor Cell Analysis: Technical and Statistical Considerations for Application to the Clinic

(2009) Alison L. Allan et al.   Journal of Oncology

Significance of Circulating Tumor Cells Detected by the CellSearch System in Patients with Metastatic Breast Colorectal and Prostate Cancer

(2009) M. Craig Miller et al.   Journal of Oncology

Surface Viscoelasticity of Individual Gram-Negative Bacterial Cells Measured Using Atomic Force Microscopy

(2008) V. Vadillo-Rodriguez et al.   JOURNAL OF BACTERIOLOGY

Continuous particle separation in spiral microchannels using dean flows and differential migration

(2008) Ali Asgar S. Bhagat et al.   LAB ON A CHIP

Prominin 1 marks intestinal stem cells that are susceptible to neoplastic transformation

(2008) Liqin Zhu et al.   NATURE