Integrating liquid biopsies into the management of cancer

Distinct subclonal tumour responses to therapy revealed by circulating cell-free DNA

(2016) G. Gremel et al.   ANNALS OF ONCOLOGY

EGFR Mutation Analysis of Circulating Tumor DNA Using an Improved PNA-LNA PCR Clamp Method

(2016) Kana Watanabe et al.   Canadian Respiratory Journal

Glioblastoma: exosome and microRNA as novel diagnosis biomarkers

(2016) L Saadatpour et al.   CANCER GENE THERAPY

Pooled Analysis of the Prognostic Relevance of Circulating Tumor Cells in Primary Breast Cancer

(2016) W. J. Janni et al.   CLINICAL CANCER RESEARCH

Association Between Plasma Genotyping and Outcomes of Treatment With Osimertinib (AZD9291) in Advanced Non–Small-Cell Lung Cancer

(2016) Geoffrey R. Oxnard et al.   JOURNAL OF CLINICAL ONCOLOGY

Somatic genomic landscape of over 15,000 patients with advanced-stage cancer from clinical next-generation sequencing analysis of circulating tumor DNA.

(2016) Oliver A. Zill et al.   JOURNAL OF CLINICAL ONCOLOGY

A Highly Sensitive and Quantitative Test Platform for Detection of NSCLC EGFR Mutations in Urine and Plasma

(2016) Karen L. Reckamp et al.   Journal of Thoracic Oncology

HER2 expression identifies dynamic functional states within circulating breast cancer cells

(2016) Nicole Vincent Jordan et al.   NATURE

Integrated digital error suppression for improved detection of circulating tumor DNA

(2016) Aaron M Newman et al.   NATURE BIOTECHNOLOGY

70-Gene Signature as an Aid to Treatment Decisions in Early-Stage Breast Cancer

(2016) Fatima Cardoso et al.   NEW ENGLAND JOURNAL OF MEDICINE

BARHL2 Methylation Using Gastric Wash DNA or Gastric Juice Exosomal DNA is a Useful Marker For Early Detection of Gastric Cancer in an H. pylori-Independent Manner

(2016) Hiroyuki Yamamoto et al.   Clinical and Translational Gastroenterology

Prospective Validation of Rapid Plasma Genotyping for the Detection ofEGFRandKRASMutations in Advanced Lung Cancer

(2016) Adrian G. Sacher et al.   JAMA Oncology

Liquid biopsy and therapeutic response: Circulating tumor cell cultures for evaluation of anticancer treatment

(2016) B. L. Khoo et al.   Science Advances

21PD_PR * PERCEPTION OF LUNG CANCER (LC) RISK: IMPACT OF SMOKING STATUS AND NICOTINE DEPENDENCE

(2015) L. Greillier et al.   ANNALS OF ONCOLOGY

Digital PCR quantification ofMGMTmethylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer

(2015) L. Barault et al.   ANNALS OF ONCOLOGY

96O * DETERMINING THE PREVALENCE OF EGFR MUTATIONS IN ASIAN AND RUSSIAN PATIENTS (PTS) WITH ADVANCED NON-SMALL-CELL LUNG CANCER (ANSCLC) OF ADENOCARCINOMA (ADC) AND NON-ADC HISTOLOGY: IGNITE STUDY

(2015) B. Han et al.   ANNALS OF ONCOLOGY

Characterizing the patterns of clonal selection in circulating tumor DNA from patients with colorectal cancer refractory to anti-EGFR treatment

(2015) M. P. Morelli et al.   ANNALS OF ONCOLOGY

Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic colorectal cancer

(2015) J. Tie et al.   ANNALS OF ONCOLOGY

Tumor-Educated Platelets as Liquid Biopsy in Cancer Patients

(2015) Simon A. Joosse et al.   CANCER CELL

Epidermal growth factor receptor mutation status in cell-free DNA supernatant of bronchial washings and brushings

(2015) Akihiko Kawahara et al.   CANCER CYTOPATHOLOGY

Establishment and Characterization of a Cell Line from Human Circulating Colon Cancer Cells

(2015) L. Cayrefourcq et al.   CANCER RESEARCH

Emergence of Multiple EGFR Extracellular Mutations during Cetuximab Treatment in Colorectal Cancer

(2015) S. Arena et al.   CLINICAL CANCER RESEARCH

Detection and Dynamic Changes of EGFR Mutations from Circulating Tumor DNA as a Predictor of Survival Outcomes in NSCLC Patients Treated with First-line Intercalated Erlotinib and Chemotherapy

(2015) T. Mok et al.   CLINICAL CANCER RESEARCH

Brain Tumor Mutations Detected in Cerebral Spinal Fluid

(2015) W. Pan et al.   CLINICAL CHEMISTRY

Analysis of circulating tumour DNA to monitor disease burden following colorectal cancer surgery

(2015) Thomas Reinert et al.   GUT

miRNA contents of cerebrospinal fluid extracellular vesicles in glioblastoma patients

(2015) Johnny C. Akers et al.   JOURNAL OF NEURO-ONCOLOGY

Circulating tumour DNA and CT monitoring in patients with untreated diffuse large B-cell lymphoma: a correlative biomarker study

(2015) Mark Roschewski et al.   LANCET ONCOLOGY

EGFR mutation detection in ctDNA from NSCLC patient plasma: A cross-platform comparison of leading technologies to support the clinical development of AZD9291

(2015) Kenneth S. Thress et al.   LUNG CANCER

Frequent expression of PD-L1 on circulating breast cancer cells

(2015) Martine Mazel et al.   Molecular Oncology

Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients

(2015) Giulia Siravegna et al.   NATURE MEDICINE

Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord

(2015) Yuxuan Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients

(2015) Peiyong Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas

(2015) Yuxuan Wang et al.   Science Translational Medicine

Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer

(2015) Isaac Garcia-Murillas et al.   Science Translational Medicine

Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer

(2015) Gaia Schiavon et al.   Science Translational Medicine

Accessing Genetic Information with Liquid Biopsies

(2015) Xuyu Cai et al.   TRENDS IN GENETICS

Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma

(2015) Leticia De Mattos-Arruda et al.   Nature Communications

Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer

(2015) Muhammed Murtaza et al.   Nature Communications

Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer

(2015) M. Russo et al.   Cancer Discovery

Tumor Heterogeneity and Lesion-Specific Response to Targeted Therapy in Colorectal Cancer

(2015) M. Russo et al.   Cancer Discovery

Characterization of DNA Methylation in Circulating Tumor Cells

(2015) Constantin Pixberg et al.   Genes

Association ofEGFRL858R Mutation in Circulating Free DNA With Survival in the EURTAC Trial

(2015) Niki Karachaliou et al.   JAMA Oncology

Exosome and Exosomal MicroRNA: Trafficking, Sorting, and Function

(2015) Jian Zhang et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Circulating microRNA Biomarkers as Liquid Biopsy for Cancer Patients: Pros and Cons of Current Assays

(2015) Shigeshi Ono et al.   Journal of Clinical Medicine

Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA

(2015) Richard B. Lanman et al.   PLoS One

Insights into therapeutic resistance from whole-genome analyses of circulating tumor DNA

(2015) Luis A. Diaz et al.   Oncotarget

Clinical utility of circulating tumor DNA for molecular assessment in pancreatic cancer

(2015) Erina Takai et al.   Scientific Reports

Towards standardisation of cell-free DNA measurement in plasma: controls for extraction efficiency, fragment size bias and quantification

(2014) Alison S. Devonshire et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle

(2014) L. De Mattos-Arruda et al.   ANNALS OF ONCOLOGY

Plasma circulating tumor DNA as an alternative to metastatic biopsies for mutational analysis in breast cancer

(2014) F. Rothé et al.   ANNALS OF ONCOLOGY

Detection of EGFR mutations in plasma and biopsies from non-small cell lung cancer patients by allele-specific PCR assays

(2014) Britta Weber et al.   BMC CANCER

Circulating Tumor DNA Is Effective for the Detection of EGFR Mutation in Non-Small Cell Lung Cancer: A Meta-analysis

(2014) M. Qiu et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Organoid Cultures Derived from Patients with Advanced Prostate Cancer

(2014) Dong Gao et al.   CELL

Double-stranded DNA in exosomes: a novel biomarker in cancer detection

(2014) Basant Kumar Thakur et al.   CELL RESEARCH

Detection of Cancer DNA in Plasma of Patients with Early-Stage Breast Cancer

(2014) J. A. Beaver et al.   CLINICAL CANCER RESEARCH

Quantitative Cell-Free Circulating BRAFV600E Mutation Analysis by Use of Droplet Digital PCR in the Follow-up of Patients with Melanoma Being Treated with BRAF Inhibitors

(2014) M. F. Sanmamed et al.   CLINICAL CHEMISTRY

Expression Profiling of Exosomal miRNAs Derived from Human Esophageal Cancer Cells by Solexa High-Throughput Sequencing

(2014) Juan Liao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Identification of Double-stranded Genomic DNA Spanning All Chromosomes with MutatedKRASandp53DNA in the Serum Exosomes of Patients with Pancreatic Cancer

(2014) Christoph Kahlert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Liquid Biopsies: Genotyping Circulating Tumor DNA

(2014) Luis A. Diaz et al.   JOURNAL OF CLINICAL ONCOLOGY

Proteomic analyses of CSF aimed at biomarker development for pediatric brain tumors

(2014) Nardin Samuel et al.   JOURNAL OF NEURO-ONCOLOGY

Multi-marker analysis of circulating cell-free DNA toward personalized medicine for colorectal cancer

(2014) Florent Mouliere et al.   Molecular Oncology

Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer

(2014) Cassandra L Hodgkinson et al.   NATURE MEDICINE

An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage

(2014) Aaron M Newman et al.   NATURE MEDICINE

Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA

(2014) Alain R Thierry et al.   NATURE MEDICINE

Clinical relevance of circulating cell-free microRNAs in cancer

(2014) Heidi Schwarzenbach et al.   Nature Reviews Clinical Oncology

Molecular analysis of circulating tumour cells—biology and biomarkers

(2014) Matthew G. Krebs et al.   Nature Reviews Clinical Oncology

Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility

(2014) M. Yu et al.   SCIENCE

Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer

(2014) S. Misale et al.   Science Translational Medicine

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

(2014) C. Bettegowda et al.   Science Translational Medicine

Circulating Cell-Free DNA from Colorectal Cancer Patients May Reveal High KRAS or BRAF Mutation Load

(2014) Florent Mouliere et al.   Translational Oncology

Blood-Based Analyses of Cancer: Circulating Tumor Cells and Circulating Tumor DNA

(2014) D. A. Haber et al.   Cancer Discovery

AZD9291, an Irreversible EGFR TKI, Overcomes T790M-Mediated Resistance to EGFR Inhibitors in Lung Cancer

(2014) D. A. E. Cross et al.   Cancer Discovery

Diagnostic value of circulating free DNA for the detection of EGFR mutation status in NSCLC: a systematic review and meta-analysis

(2014) Jie Luo et al.   Scientific Reports

Circulating cell-free DNA as a promising biomarker in patients with gastric cancer: diagnostic validity and significant reduction of cfDNA after surgical resection

(2014) Kyongchol Kim et al.   Annals of Surgical Treatment and Research

Stability of miRNA in human urine supports its biomarker potential

(2013) Christine Mall et al.   Biomarkers in Medicine

First-line gefitinib in Caucasian EGFR mutation-positive NSCLC patients: a phase-IV, open-label, single-arm study

(2013) J-Y Douillard et al.   BRITISH JOURNAL OF CANCER

Early detection of nasopharyngeal carcinoma by plasma Epstein-Barr virus DNA analysis in a surveillance program

(2013) K. C. Allen Chan et al.   CANCER

Circulating cell free DNA: Preanalytical considerations

(2013) Safia El Messaoudi et al.   CLINICA CHIMICA ACTA

Methylation of the hTERT Promoter: A Novel Cancer Biomarker for Leptomeningeal Metastasis Detection in Cerebrospinal Fluids

(2013) S. Bougel et al.   CLINICAL CANCER RESEARCH

Multiplex Picodroplet Digital PCR to Detect KRAS Mutations in Circulating DNA from the Plasma of Colorectal Cancer Patients

(2013) V. Taly et al.   CLINICAL CHEMISTRY

Downregulation of cell-free miR-198 as a diagnostic biomarker for lung adenocarcinoma-associated malignant pleural effusion

(2013) Hye-Suk Han et al.   INTERNATIONAL JOURNAL OF CANCER

Establishment of tumor-specific copy number alterations from plasma DNA of patients with cancer

(2013) Ellen Heitzer et al.   INTERNATIONAL JOURNAL OF CANCER

Phase III Study of Afatinib or Cisplatin Plus Pemetrexed in Patients With Metastatic Lung Adenocarcinoma WithEGFRMutations

(2013) Lecia V. Sequist et al.   JOURNAL OF CLINICAL ONCOLOGY

Does T790M Disappear? Successful Gefitinib Rechallenge After T790M Disappearance in a Patient With EGFR-Mutant Non–Small-Cell Lung Cancer

(2013) Akito Hata et al.   Journal of Thoracic Oncology

Quantitation of cell-free DNA and RNA in plasma during tumor progression in rats

(2013) Dolores C García-Olmo et al.   Molecular Cancer

Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA

(2013) Muhammed Murtaza et al.   NATURE

Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay

(2013) Irène Baccelli et al.   NATURE BIOTECHNOLOGY

Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer

(2013) Sarah-Jane Dawson et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immunosuppressive networks and checkpoints controlling antitumor immunity and their blockade in the development of cancer immunotherapeutics and vaccines

(2013) A Q Butt et al.   ONCOGENE

Cerebrospinal Fluid Secretion by the Choroid Plexus

(2013) Helle H. Damkier et al.   PHYSIOLOGICAL REVIEWS

Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing

(2013) K. C. A. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition

(2013) M. Yu et al.   SCIENCE

The Identification and Characterization of Breast Cancer CTCs Competent for Brain Metastasis

(2013) L. Zhang et al.   Science Translational Medicine

Amplification of the MET Receptor Drives Resistance to Anti-EGFR Therapies in Colorectal Cancer

(2013) Alberto Bardelli et al.   Cancer Discovery

Biologic Challenges in the Detection of Circulating Tumor Cells

(2012) S. A. Joosse et al.   CANCER RESEARCH

Ultrasensitive Measurement of Hotspot Mutations in Tumor DNA in Blood Using Error-Suppressed Multiplexed Deep Sequencing

(2012) A. Narayan et al.   CANCER RESEARCH

Quantitative Cell-Free DNA, KRAS, and BRAF Mutations in Plasma from Patients with Metastatic Colorectal Cancer during Treatment with Cetuximab and Irinotecan

(2012) K.-L. G. Spindler et al.   CLINICAL CANCER RESEARCH

Detection of Tumor PIK3CA Status in Metastatic Breast Cancer Using Peripheral Blood

(2012) M. J. Higgins et al.   CLINICAL CANCER RESEARCH

Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing

(2012) K. C. A. Chan et al.   CLINICAL CHEMISTRY

Circulating Tumor Cells: Liquid Biopsy of Cancer

(2012) C. Alix-Panabieres et al.   CLINICAL CHEMISTRY

Medulloblastoma

(2012) Katja von Hoff et al.   Current Treatment Options in Neurology

Detection of promoter methylation of tumor suppressor genes in serum DNA of breast cancer cases and benign breast disease controls

(2012) Susan R. Sturgeon et al.   Epigenetics

Quantitative Measurement of Cell-Free Plasma DNA and Applications for Detecting Tumor Genetic Variation and Promoter Methylation in a Clinical Setting

(2012) Sunil K. Kadam et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Application of a Highly Sensitive Detection System for Epidermal Growth Factor Receptor Mutations in Plasma DNA

(2012) Tomomi Nakamura et al.   Journal of Thoracic Oncology

Successful rechallenge in two patients with BRAF-V600-mutant melanoma who experienced previous progression during treatment with a selective BRAF inhibitor

(2012) Amélie Clémentine Seghers et al.   MELANOMA RESEARCH

The Majority of MicroRNAs Detectable in Serum and Saliva Is Concentrated in Exosomes

(2012) Alessia Gallo et al.   PLoS One

Single Cell Profiling of Circulating Tumor Cells: Transcriptional Heterogeneity and Diversity from Breast Cancer Cell Lines

(2012) Ashley A. Powell et al.   PLoS One

Cell-Free MicroRNA Expression Profiles in Malignant Effusion Associated with Patient Survival in Non-Small Cell Lung Cancer

(2012) Tingting Wang et al.   PLoS One

High Resolution Size Analysis of Fetal DNA in the Urine of Pregnant Women by Paired-End Massively Parallel Sequencing

(2012) Nancy B. Y. Tsui et al.   PLoS One

Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA

(2012) T. Forshew et al.   Science Translational Medicine

Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing

(2012) R. J. Leary et al.   Science Translational Medicine

Differences in the quantity of DNA found in the urine and saliva of smokers versus nonsmokers: implications for the timing of epigenetic events

(2012) Melissa Simkin et al.   Epigenomics

High-Throughput Droplet Digital PCR System for Absolute Quantitation of DNA Copy Number

(2011) Benjamin J. Hindson et al.   ANALYTICAL CHEMISTRY

Circulating Tumor Cells and Circulating Tumor DNA

(2011) Catherine Alix-Panabières et al.   Annual Review of Medicine

Identification of microRNAs in the cerebrospinal fluid as marker for primary diffuse large B-cell lymphoma of the central nervous system

(2011) A. Baraniskin et al.   BLOOD

Circulating Tumor Cells in Breast Cancer: Detection Systems, Molecular Characterization, and Future Challenges

(2011) E. S. Lianidou et al.   CLINICAL CHEMISTRY

Circulating tumor cells: approaches to isolation and characterization

(2011) Min Yu et al.   JOURNAL OF CELL BIOLOGY

Evaluation and Prognostic Significance of Circulating Tumor Cells in Patients With Non–Small-Cell Lung Cancer

(2011) Matthew G. Krebs et al.   JOURNAL OF CLINICAL ONCOLOGY

Multiplex Amplification Coupled with COLD-PCR and High Resolution Melting Enables Identification of Low-Abundance Mutations in Cancer Samples with Low DNA Content

(2011) Coren A. Milbury et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study

(2011) Caicun Zhou et al.   LANCET ONCOLOGY

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

Characterization of extracellular circulating microRNA

(2011) Andrey Turchinovich et al.   NUCLEIC ACIDS RESEARCH

Detection and quantification of rare mutations with massively parallel sequencing

(2011) I. Kinde et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating tumour cells demonstrate an altered response to hypoxia and an aggressive phenotype

(2010) K Ameri et al.   BRITISH JOURNAL OF CANCER

Differential methylation of cell-free circulating DNA among patients with pancreatic cancer versus chronic pancreatitis

(2010) Thomas Liggett et al.   CANCER

Circulating Tumor Cells in the Management of Breast Cancer

(2010) Govardhanan Nagaiah et al.   Clinical Breast Cancer

Portable Filter-Based Microdevice for Detection and Characterization of Circulating Tumor Cells

(2010) H. K. Lin et al.   CLINICAL CANCER RESEARCH

Use of cancer-specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors

(2010) David J. McBride et al.   GENES CHROMOSOMES & CANCER

Detection of Low-Level KRAS Mutations Using PNA-Mediated Asymmetric PCR Clamping and Melting Curve Analysis with Unlabeled Probes

(2010) Ji Eun Oh et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Exosomes: Extracellular organelles important in intercellular communication

(2010) Suresh Mathivanan et al.   Journal of Proteomics

Overdiagnosis in Cancer

(2010) H. G. Welch et al.   JNCI-Journal of the National Cancer Institute

Isolation and Characterization of Circulating Tumor Cells from Patients with Localized and Metastatic Prostate Cancer

(2010) S. L. Stott et al.   Science Translational Medicine

Development of Personalized Tumor Biomarkers Using Massively Parallel Sequencing

(2010) R. J. Leary et al.   Science Translational Medicine

Maternal Plasma DNA Sequencing Reveals the Genome-Wide Genetic and Mutational Profile of the Fetus

(2010) Y. M. D. Lo et al.   Science Translational Medicine

Circulating tumour cells: their utility in cancer management and predicting outcomes

(2010) Matthew G. Krebs et al.   Therapeutic Advances in Medical Oncology

Transrenal Nucleic Acids: From Proof of Principle to Clinical Tests

(2009) Hovsep S. Melkonyan et al.   Annals of the New York Academy of Sciences

Correlation of HER2 status between primary tumors and corresponding circulating tumor cells in advanced breast cancer patients

(2009) Marta Pestrin et al.   BREAST CANCER RESEARCH AND TREATMENT

PCR-Based Methods for Detecting Single-Locus DNA Methylation Biomarkers in Cancer Diagnostics, Prognostics, and Response to Treatment

(2009) L. S. Kristensen et al.   CLINICAL CHEMISTRY

Exosomal MicroRNA: A Diagnostic Marker for Lung Cancer

(2009) Guilherme Rabinowits et al.   Clinical Lung Cancer

Exosomes – vesicular carriers for intercellular communication

(2009) Mikael Simons et al.   CURRENT OPINION IN CELL BIOLOGY

CpG Island Hypermethylation of Cell-Free Circulating Serum DNA in Patients With Testicular Cancer

(2009) Jörg Ellinger et al.   JOURNAL OF UROLOGY

Novel mutant-selective EGFR kinase inhibitors against EGFR T790M

(2009) Wenjun Zhou et al.   NATURE

Sensitive digital quantification of DNA methylation in clinical samples

(2009) Meng Li et al.   NATURE BIOTECHNOLOGY

Gene-Expression Signatures in Breast Cancer

(2009) Christos Sotiriou et al.   NEW ENGLAND JOURNAL OF MEDICINE

Shedding microvesicles: artefacts no more

(2009) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Quantitative and qualitative characterization of plasma DNA identifies primary and recurrent colorectal cancer

(2008) M. Frattini et al.   CANCER LETTERS

Circulating Tumor Cells Predict Survival Benefit from Treatment in Metastatic Castration-Resistant Prostate Cancer

(2008) J. S. de Bono et al.   CLINICAL CANCER RESEARCH

Analysis of Mutations in DNA Isolated From Plasma and Stool of Colorectal Cancer Patients

(2008) Frank Diehl et al.   GASTROENTEROLOGY

MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer

(2008) Douglas D. Taylor et al.   GYNECOLOGIC ONCOLOGY

Relationship of Circulating Tumor Cells to Tumor Response, Progression-Free Survival, and Overall Survival in Patients With Metastatic Colorectal Cancer

(2008) Steven J. Cohen et al.   JOURNAL OF CLINICAL ONCOLOGY

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

Circulating mutant DNA to assess tumor dynamics

(2008) Frank Diehl et al.   NATURE MEDICINE

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA