Towards Improvements for Penetrating the Blood–Brain Barrier—Recent Progress from a Material and Pharmaceutical Perspective

Magnetic graphene oxide inlaid with silver nanoparticles as antibacterial and drug delivery composite

(2018) Mohammad Kooti et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Nanosystems in nose-to-brain drug delivery: A review of non-clinical brain targeting studies

(2018) Patrícia C. Pires et al.   JOURNAL OF CONTROLLED RELEASE

Chemically Surface Tunable Solubility Parameter for Controllable Drug Delivery—An Example and Perspective from Hollow PAA-Coated Magnetite Nanoparticles with R6G Model Drug

(2018) Quanguo He et al.   Materials

Sodium Acetate Orientated Hollow/Mesoporous Magnetite Nanoparticles: Facile Synthesis, Characterization and Formation Mechanism

(2018) Quanguo He et al.   Applied Sciences-Basel

Gut reactions: How the blood–brain barrier connects the microbiome and the brain

(2017) Aric F Logsdon et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Nanomedicine formulations for the delivery of antiviral drugs: a promising solution for the treatment of viral infections

(2017) David Lembo et al.   Expert Opinion on Drug Delivery

Carotid Artery Stenting and Blood–Brain Barrier Permeability in Subjects with Chronic Carotid Artery Stenosis

(2017) Arkadiusz Szarmach et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Magnetic Nanoparticles in the Central Nervous System: Targeting Principles, Applications and Safety Issues

(2017) Federico D’Agata et al.   MOLECULES

A New Noncanonical Anionic Peptide That Translocates a Cellular Blood–Brain Barrier Model

(2017) Sara Neves-Coelho et al.   MOLECULES

Resveratrol and Grape Extract-loaded Solid Lipid Nanoparticles for the Treatment of Alzheimer’s Disease

(2017) Joana Loureiro et al.   MOLECULES

L-Borneol induces transient opening of the blood–brain barrier and enhances the therapeutic effect of cisplatin

(2017) Yi Yin et al.   NEUROREPORT

Core Concept: Circumventing the blood–brain barrier

(2017) Helen H. Shen   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoparticle-Based Therapeutics for Brain Injury

(2017) Vimala N. Bharadwaj et al.   Advanced Healthcare Materials

Time-sequenced drug delivery approaches towards effective chemotherapeutic treatment of glioma

(2017) Menghuan Li et al.   Materials Horizons

ANG1005: Results of a phase I study in patients with recurrent malignant glioma.

(2017) J. Drappatz et al.   JOURNAL OF CLINICAL ONCOLOGY

Revisiting nanoparticle technology for blood–brain barrier transport: Unfolding at the endothelial gate improves the fate of transferrin receptor-targeted liposomes

(2016) Kasper Bendix Johnsen et al.   JOURNAL OF CONTROLLED RELEASE

Strategies to Inhibit ABCB1- and ABCG2-Mediated Efflux Transport of Erlotinib at the Blood–Brain Barrier: A PET Study on Nonhuman Primates

(2016) Nicolas Tournier et al.   JOURNAL OF NUCLEAR MEDICINE

Innovative Technologies in Nanomedicines: From Passive Targeting to Active Targeting/From Controlled Pharmacokinetics to Controlled Intracellular Pharmacokinetics

(2016) Yusuke Sato et al.   MACROMOLECULAR BIOSCIENCE

Particle tracking in drug and gene delivery research: State-of-the-art applications and methods

(2015) Benjamin S. Schuster et al.   ADVANCED DRUG DELIVERY REVIEWS

Blood-brain barrier: An impediment to neuropharmaceuticals

(2015) JT Henderson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Intranasal delivery: circumventing the iron curtain to treat neurological disorders

(2015) Yongjun Jiang et al.   Expert Opinion on Drug Delivery

Focused ultrasound-mediated drug delivery through the blood–brain barrier

(2015) Alison Burgess et al.   Expert Review of Neurotherapeutics

Blood–brain barrier transport studies, aggregation, and molecular dynamics simulation of multiwalled carbon nanotube functionalized with fluorescein isothiocyanate

(2015) Sergey Shityakov et al.   International Journal of Nanomedicine

Antibody-drug conjugates as drug carrier systems for bioactive agents

(2015) Muhammad Sajid Hamid Akash et al.   International Journal of Polymeric Materials and Polymeric Biomaterials

LSR/angulin-1 is a tricellular tight junction protein involved in blood–brain barrier formation

(2015) Fabien Sohet et al.   JOURNAL OF CELL BIOLOGY

Approaching Complete Inhibition of P-Glycoprotein at the Human Blood–Brain Barrier: An (R)-[11C]Verapamil PET Study

(2015) Martin Bauer et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Effects of the microbubble shell physicochemical properties on ultrasound-mediated drug delivery to the brain

(2015) Shih-Ying Wu et al.   JOURNAL OF CONTROLLED RELEASE

Remote control of the permeability of the blood–brain barrier by magnetic heating of nanoparticles: A proof of concept for brain drug delivery

(2015) Seyed Nasrollah Tabatabaei et al.   JOURNAL OF CONTROLLED RELEASE

Therapeutic strategies to improve drug delivery across the blood-brain barrier

(2015) Tej D. Azad et al.   Neurosurgical Focus

Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio

(2015) Tianzhi Yang et al.   PHARMACEUTICAL RESEARCH

Enhancement in blood-tumor barrier permeability and delivery of liposomal doxorubicin using focused ultrasound and microbubbles: evaluation during tumor progression in a rat glioma model

(2015) Muna Aryal et al.   PHYSICS IN MEDICINE AND BIOLOGY

Vascular endothelial growth factor antagonism restores epithelial barrier dysfunction via affecting zonula occludens proteins

(2015) HASAN YUKSEL et al.   Experimental and Therapeutic Medicine

Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism

(2015) Iben Lundgaard et al.   Nature Communications

Preparation of Silica Nanoparticles Loaded with Nootropics and TheirIn VivoPermeation through Blood-Brain Barrier

(2015) Josef Jampilek et al.   Biomed Research International

Focused ultrasound-mediated drug delivery through the blood–brain barrier

(2015) Alison Burgess et al.   Expert Review of Neurotherapeutics

Antibody-drug conjugates as drug carrier systems for bioactive agents

(2015) Muhammad Sajid Hamid Akash et al.   International Journal of Polymeric Materials and Polymeric Biomaterials

Enhancement of Blood–Brain Barrier Permeability and Delivery of Antisense Oligonucleotides or Plasmid DNA to the Brain by the Combination of Bubble Liposomes and High-Intensity Focused Ultrasound

(2015) Yoichi Negishi et al.   Pharmaceutics

Ultrasound-mediated blood–brain barrier disruption for targeted drug delivery in the central nervous system

(2014) Muna Aryal et al.   ADVANCED DRUG DELIVERY REVIEWS

Recent Advances in Delivery Through the Blood-Brain Barrier

(2014) Jessica Larsen et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Microemulsion-based drug delivery system for transnasal delivery of Carbamazepine: preliminary brain-targeting study

(2014) Rashmin Bharatbhai Patel et al.   DRUG DELIVERY

Blood–brain barrier models and their relevance for a successful development of CNS drug delivery systems: A review

(2014) Joana Bicker et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Cell-Based in Vitro Blood–Brain Barrier Model Can Rapidly Evaluate Nanoparticles’ Brain Permeability in Association with Particle Size and Surface Modification

(2014) Sanshiro Hanada et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Superparamagnetic iron oxide nanoparticles conjugated with epidermal growth factor (SPION–EGF) for targeting brain tumors

(2014) Shevtsov et al.   International Journal of Nanomedicine

Intra-arterial delivery of AAV vectors to the mouse brain after mannitol mediated blood brain barrier disruption

(2014) Conor P. Foley et al.   JOURNAL OF CONTROLLED RELEASE

Breaching the Blood-Brain Barrier for Drug Delivery

(2014) Robert D. Bell et al.   NEURON

Drug Delivery Systems, CNS Protection, and the Blood Brain Barrier

(2014) Ravi Kant Upadhyay   Biomed Research International

Smuggling Drugs into the Brain: An Overview of Ligands Targeting Transcytosis for Drug Delivery across the Blood–Brain Barrier

(2014) Julia Georgieva et al.   Pharmaceutics

Cell-Penetrating Peptide-Mediated Therapeutic Molecule Delivery into the Central Nervous System

(2013) Li-Li Zou et al.   Current Neuropharmacology

The mechanism of the opening of the blood–brain barrier by borneol: A pharmacodynamics and pharmacokinetics combination study

(2013) Bin Yu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Blood–brain barrier structure and function and the challenges for CNS drug delivery

(2013) N. Joan Abbott   JOURNAL OF INHERITED METABOLIC DISEASE

The Blood-Brain Barrier

(2013) Felix Dyrna et al.   Journal of Neuroimmune Pharmacology

Mannitol enhances therapeutic effects of intra-arterial transplantation of mesenchymal stem cells into the brain after traumatic brain injury

(2013) Yu Okuma et al.   NEUROSCIENCE LETTERS

The Use of Borneol as an Enhancer for Targeting Aprotinin-Conjugated PEG-PLGA Nanoparticles to the Brain

(2013) Lin Zhang et al.   PHARMACEUTICAL RESEARCH

Receptor-Mediated Delivery of Magnetic Nanoparticles across the Blood–Brain Barrier

(2012) Ruirui Qiao et al.   ACS Nano

Overview of P-glycoprotein inhibitors: a rational outlook

(2012) Kale Mohana Raghava Srivalli et al.   Brazilian Journal of Pharmaceutical Sciences

Penetratin-functionalized PEG–PLA nanoparticles for brain drug delivery

(2012) Huimin Xia et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Enhanced brain delivery of liposomal methylprednisolone improved therapeutic efficacy in a model of neuroinflammation

(2012) Pieter J. Gaillard et al.   JOURNAL OF CONTROLLED RELEASE

Magnetic targeting of nanoparticles across the intact blood–brain barrier

(2012) Seong Deok Kong et al.   JOURNAL OF CONTROLLED RELEASE

PLGA-based nanoparticles: An overview of biomedical applications

(2012) Fabienne Danhier et al.   JOURNAL OF CONTROLLED RELEASE

Aerosols implicated as a prime driver of twentieth-century North Atlantic climate variability

(2012) Ben B. B. Booth et al.   NATURE

PEGylation and polyPEGylation of nanodiamond

(2012) Xiaoyong Zhang et al.   POLYMER

Liposomes: From a Clinically Established Drug Delivery System to a Nanoparticle Platform for Theranostic Nanomedicine

(2011) Wafa’ T. Al-Jamal et al.   ACCOUNTS OF CHEMICAL RESEARCH

Claudin-1 induced sealing of blood–brain barrier tight junctions ameliorates chronic experimental autoimmune encephalomyelitis

(2011) Friederike Pfeiffer et al.   ACTA NEUROPATHOLOGICA

Formulation design, preparation and physicochemical characterizations of solid lipid nanoparticles containing a hydrophobic drug: Effects of process variables

(2011) Surajit Das et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Pharmacokinetics of natural borneol after oral administration in mice brain and its effect on excitation ratio

(2011) Wei-rong Li et al.   EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS

Toward Eradicating HIV Reservoirs in the Brain: Inhibiting P-Glycoprotein at the Blood–Brain Barrier with Prodrug Abacavir Dimers

(2011) Hilda A. Namanja et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient Chemotherapy of Rat Glioblastoma Using Doxorubicin-Loaded PLGA Nanoparticles with Different Stabilizers

(2011) Stefanie Wohlfart et al.   PLoS One

PEGlated magnetic polymeric liposome anchored with TAT for delivery of drugs across the blood-spinal cord barrier

(2010) Hanjie Wang et al.   BIOMATERIALS

Lactoferrin-modified procationic liposomes as a novel drug carrier for brain delivery

(2010) Huali Chen et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Low-frequency sonophoresis: application to the transdermal delivery of macromolecules and hydrophilic drugs

(2010) Baris E Polat et al.   Expert Opinion on Drug Delivery

The distribution and expression of claudin-5 and occludin at the rat blood–optic nerve barrier after borneol treatment

(2010) Di Jin et al.   MOLECULAR BIOLOGY REPORTS

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Magnetic resonance monitoring of focused ultrasound/magnetic nanoparticle targeting delivery of therapeutic agents to the brain

(2010) H.-L. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging

(2009) Omid Veiseh et al.   ADVANCED DRUG DELIVERY REVIEWS

Biodegradable polymeric nanoparticles based drug delivery systems

(2009) Avnesh Kumari et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Structure and function of the blood–brain barrier

(2009) N. Joan Abbott et al.   NEUROBIOLOGY OF DISEASE

Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancer

(2009) Yogeshkumar Malam et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Recent Advances in Blood–Brain Barrier Disruption as a CNS Delivery Strategy

(2008) Marc-André Bellavance et al.   AAPS Journal

Prodrug Approaches for CNS Delivery

(2008) Jarkko Rautio et al.   AAPS Journal

Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease

(2008) Barnabas Wilson et al.   BRAIN RESEARCH

Protein components of the blood–brain barrier (BBB) in the mediobasal hypothalamus

(2008) Ebba Norsted et al.   JOURNAL OF CHEMICAL NEUROANATOMY

Preparation and brain delivery property of biodegradable polymersomes conjugated with OX26

(2008) Zhiqing Pang et al.   JOURNAL OF CONTROLLED RELEASE

Blood-Brain Barrier Disruption Induced by Focused Ultrasound and Circulating Preformed Microbubbles Appears to Be Characterized by the Mechanical Index

(2008) Nathan McDannold et al.   ULTRASOUND IN MEDICINE AND BIOLOGY