Smuggling Drugs into the Brain: An Overview of Ligands Targeting Transcytosis for Drug Delivery across the Blood–Brain Barrier
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Smuggling Drugs into the Brain: An Overview of Ligands Targeting Transcytosis for Drug Delivery across the Blood–Brain Barrier
Authors
Keywords
-
Journal
Pharmaceutics
Volume 6, Issue 4, Pages 557-583
Publisher
MDPI AG
Online
2014-11-17
DOI
10.3390/pharmaceutics6040557
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Apical-to-Basolateral Transport of Amyloid-β Peptides through Blood-Brain Barrier Cells is Mediated by the Receptor for Advanced Glycation End-Products and is Restricted by P-Glycoprotein
- (2017) Pietra Candela et al. JOURNAL OF ALZHEIMERS DISEASE
- Glutathione PEGylated liposomes: pharmacokinetics and delivery of cargo across the blood–brain barrier in rats
- (2014) Jaap Rip et al. JOURNAL OF DRUG TARGETING
- Abstract B76: A phase II study of ANG1005, a novel, brain-penetrant taxane derivative, in breast cancer patients with brain metastases.
- (2014) N. U. Lin et al. MOLECULAR CANCER THERAPEUTICS
- Mfsd2a is critical for the formation and function of the blood–brain barrier
- (2014) Ayal Ben-Zvi et al. NATURE
- Increased Brain Penetration and Potency of a Therapeutic Antibody Using a Monovalent Molecular Shuttle
- (2014) Jens Niewoehner et al. NEURON
- Pharmacokinetics, Brain Delivery, and Efficacy in Brain Tumor-Bearing Mice of Glutathione Pegylated Liposomal Doxorubicin (2B3-101)
- (2014) Pieter J. Gaillard et al. PLoS One
- Nanoparticles of 2-deoxy-d-glucose functionalized poly(ethylene glycol)-co-poly(trimethylene carbonate) for dual-targeted drug delivery in glioma treatment
- (2013) Xinyi Jiang et al. BIOMATERIALS
- Glucose-Coated Gold Nanoparticles Transfer across Human Brain Endothelium and Enter Astrocytes In Vitro
- (2013) Radka Gromnicova et al. PLoS One
- Peptide-Mediated Blood-Brain Barrier Transport of Polymersomes
- (2012) Julia V. Georgieva et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Investigation of glucose-modified liposomes using polyethylene glycols with different chain lengths as the linkers for brain targeting
- (2012) Fulan Xie et al. International Journal of Nanomedicine
- A Monoclonal Antibody-GDNF Fusion Protein Is Not Neuroprotective and Is Associated with Proliferative Pancreatic Lesions in Parkinsonian Monkeys
- (2012) Sachiko Ohshima-Hosoyama et al. PLoS One
- In Vivo Labeling of Brain Capillary Endothelial Cells after Intravenous Injection of Monoclonal Antibodies Targeting the Transferrin Receptor
- (2011) S. Paris-Robidas et al. MOLECULAR PHARMACOLOGY
- Investigation on mechanisms of glycopeptide nanoparticles for drug delivery across the blood–brain barrier
- (2011) Giovanni Tosi et al. Nanomedicine
- Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes
- (2011) Lydia Alvarez-Erviti et al. NATURE BIOTECHNOLOGY
- Engaging neuroscience to advance translational research in brain barrier biology
- (2011) Edward A. Neuwelt et al. NATURE REVIEWS NEUROSCIENCE
- Boosting Brain Uptake of a Therapeutic Antibody by Reducing Its Affinity for a Transcytosis Target
- (2011) Y. J. Yu et al. Science Translational Medicine
- Leptin-derived peptide, a targeting ligand for mouse brain-derived endothelial cells via macropinocytosis
- (2010) Mina Tamaru et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Selective targeting of a TNFR decoy receptor pharmaceutical to the primate brain as a receptor-specific IgG fusion protein
- (2010) Ruben J. Boado et al. JOURNAL OF BIOTECHNOLOGY
- Comparison of five different targeting ligands to enhance accumulation of liposomes into the brain
- (2010) Inge van Rooy et al. JOURNAL OF CONTROLLED RELEASE
- Human serum albumin nanoparticles modified with apolipoprotein A-I cross the blood-brain barrier and enter the rodent brain
- (2010) Anja Zensi et al. JOURNAL OF DRUG TARGETING
- Biopharmaceutical drug targeting to the brain
- (2010) William M. Pardridge JOURNAL OF DRUG TARGETING
- In vitroandin vivoinvestigation of glucose-mediated brain-targeting liposomes
- (2010) Yao Qin et al. JOURNAL OF DRUG TARGETING
- Surface Characteristics of Nanoparticles Determine Their Intracellular Fate in and Processing by Human Blood–Brain Barrier Endothelial Cells In Vitro
- (2010) Julia V Georgieva et al. MOLECULAR THERAPY
- Delivery of amphotericin B nanosuspensions to the brain and determination of activity against Balamuthia mandrillaris amebas
- (2010) Andreas Lemke et al. Nanomedicine-Nanotechnology Biology and Medicine
- Pericytes regulate the blood–brain barrier
- (2010) Annika Armulik et al. NATURE
- Pericytes are required for blood–brain barrier integrity during embryogenesis
- (2010) Richard Daneman et al. NATURE
- Multifunctional Nanocarriers for diagnostics, drug delivery and targeted treatment across blood-brain barrier: perspectives on tracking and neuroimaging
- (2010) Sonu Bhaskar et al. Particle and Fibre Toxicology
- Nano-interventions for neurodegenerative disorders
- (2010) Clara Fernandes et al. PHARMACOLOGICAL RESEARCH
- Exploring the caves: cavins, caveolins and caveolae
- (2010) Carsten G. Hansen et al. TRENDS IN CELL BIOLOGY
- Albumin nanoparticles targeted with Apo E enter the CNS by transcytosis and are delivered to neurones
- (2009) Anja Zensi et al. JOURNAL OF CONTROLLED RELEASE
- Nanoparticles as drug delivery agents specific for CNS: in vivo biodistribution
- (2009) Anna Valeria Vergoni et al. Nanomedicine-Nanotechnology Biology and Medicine
- Macropinocytosis in Shiga toxin 1 uptake by human intestinal epithelial cells and transcellular transcytosis
- (2008) Irina Malyukova et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- TAT-conjugated nanoparticles for the CNS delivery of anti-HIV drugs
- (2008) Kavitha S. Rao et al. BIOMATERIALS
- Antitumour activity of ANG1005, a conjugate between paclitaxel and the new brain delivery vector Angiopep-2
- (2008) A Régina et al. BRITISH JOURNAL OF PHARMACOLOGY
- Endothelial transcytosis in health and disease
- (2008) Maya Simionescu et al. CELL AND TISSUE RESEARCH
- Physiological Pathway for Low-Density Lipoproteins across the Blood-Brain Barrier: Transcytosis through Brain Capillary Endothelial Cells In Vitro
- (2008) Pietra Candela et al. ENDOTHELIUM-JOURNAL OF ENDOTHELIAL CELL RESEARCH
- Targeted delivery of tacrine into the brain with polysorbate 80-coated poly(n-butylcyanoacrylate) nanoparticles
- (2008) B WILSON et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Transferrin- and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood–brain barrier (BBB)
- (2008) Karsten Ulbrich et al. EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS
- Preparation and brain delivery property of biodegradable polymersomes conjugated with OX26
- (2008) Zhiqing Pang et al. JOURNAL OF CONTROLLED RELEASE
- Involvement of the low-density lipoprotein receptor-related protein in the transcytosis of the brain delivery vector Angiopep-2
- (2008) Michel Demeule et al. JOURNAL OF NEUROCHEMISTRY
- Yersinia pseudotuberculosis induces transcytosis of nanoparticles across human intestinal villus epithelium via invasin-dependent macropinocytosis
- (2008) Eva G E Ragnarsson et al. LABORATORY INVESTIGATION
- The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders
- (2008) Berislav V. Zlokovic NEURON
- A Unique Carrier for Delivery of Therapeutic Compounds beyond the Blood-Brain Barrier
- (2008) Delara Karkan et al. PLoS One
- Biologically active core/shell nanoparticles self-assembled from cholesterol-terminated PEG–TAT for drug delivery across the blood–brain barrier
- (2007) Lihong Liu et al. BIOMATERIALS
- Restricted transport of anti-transferrin receptor antibody (OX26) through the blood-brain barrier in the rat
- (2003) Torben Moos et al. JOURNAL OF NEUROCHEMISTRY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started