Type 2 diabetes impairs odour detection, olfactory memory and olfactory neuroplasticity; effects partly reversed by the DPP-4 inhibitor Linagliptin
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Title
Type 2 diabetes impairs odour detection, olfactory memory and olfactory neuroplasticity; effects partly reversed by the DPP-4 inhibitor Linagliptin
Authors
Keywords
Diabetes, DPP-4 inhibitors, Goto-Kakizaki rats, Olfaction, Neuroplasticity, Piriform cortex
Journal
Acta Neuropathologica Communications
Volume 6, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-02-23
DOI
10.1186/s40478-018-0517-1
References
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Note: Only part of the references are listed.- Differential Expression of Interneuron Populations and Correlation with Amyloid-β Deposition in the Olfactory Cortex of an AβPP/PS1 Transgenic Mouse Model of Alzheimer's Disease
- (2018) Daniel Saiz-Sanchez et al. JOURNAL OF ALZHEIMERS DISEASE
- Pentamethylquercetin Protects Against Diabetes-Related Cognitive Deficits in Diabetic Goto-Kakizaki Rats
- (2018) Xian-Hui Li et al. JOURNAL OF ALZHEIMERS DISEASE
- Evidence for Cortical Neuronal Loss in Male Type 2 Diabetic Goto-Kakizaki Rats
- (2018) Shafaat Hussain et al. JOURNAL OF ALZHEIMERS DISEASE
- Olfactory and gustatory functions in patients with non-complicated type 1 diabetes mellitus
- (2017) Aytug Altundag et al. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
- Prevalence and Correlates of Olfactory Dysfunction in Old Age: A Population-Based Study
- (2017) Janina Seubert et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Olfactory dysfunction in neurodegenerative diseases: is there a common pathological substrate?
- (2017) Richard L Doty LANCET NEUROLOGY
- Brain GLP-1/IGF-1 Signaling and Autophagy Mediate Exendin-4 Protection Against Apoptosis in Type 2 Diabetic Rats
- (2017) Emanuel Candeias et al. MOLECULAR NEUROBIOLOGY
- Early ciliary and prominin-1 dysfunctions precede neurogenesis impairment in a mouse model of type 2 diabetes
- (2017) Tomás P. Bachor et al. NEUROBIOLOGY OF DISEASE
- Type 2 diabetes alters hippocampal gamma oscillations: A potential mechanism behind impaired cognition
- (2017) Grazyna Lietzau et al. PSYCHONEUROENDOCRINOLOGY
- SGLT2-inhibitor and DPP-4 inhibitor improve brain function via attenuating mitochondrial dysfunction, insulin resistance, inflammation, and apoptosis in HFD-induced obese rats
- (2017) Piangkwan Sa-nguanmoo et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Linagliptin treatment improves cerebrovascular function and remodeling and restores reduced cerebral perfusion in Type 2 diabetes
- (2016) Trevor Hardigan et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Gliptin-mediated neuroprotection against stroke requires chronic pretreatment and is independent of glucagon-like peptide-1 receptor
- (2016) V. Darsalia et al. DIABETES OBESITY & METABOLISM
- Interneurons in the human olfactory system in Alzheimer's disease
- (2016) Daniel Saiz-Sanchez et al. EXPERIMENTAL NEUROLOGY
- Impairment of synaptic development in the hippocampus of diabetic Goto-Kakizaki rats
- (2016) Yuki Matsunaga et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Diabetes Impairs Wnt3 Protein-induced Neurogenesis in Olfactory Bulbs via Glutamate Transporter 1 Inhibition
- (2016) Tamami Wakabayashi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Linagliptin, a Dipeptidyl Peptidase-4 Inhibitor, Mitigates Cognitive Deficits and Pathology in the 3xTg-AD Mouse Model of Alzheimer’s Disease
- (2016) Jayasankar Kosaraju et al. MOLECULAR NEUROBIOLOGY
- Olfactory memory in the old and very old: relations to episodic and semantic memory and APOE genotype
- (2016) Maria Larsson et al. NEUROBIOLOGY OF AGING
- Type 2 diabetes-induced neuronal pathology in the piriform cortex of the rat is reversed by the GLP-1 receptor agonist exendin-4
- (2016) Grazyna Lietzau et al. Oncotarget
- High Fructose Diet inducing diabetes rapidly impacts olfactory epithelium and behavior in mice
- (2016) Sébastien Rivière et al. Scientific Reports
- Fus1 KO Mouse As a Model of Oxidative Stress-Mediated Sporadic Alzheimer's Disease: Circadian Disruption and Long-Term Spatial and Olfactory Memory Impairments
- (2016) Guillermo Coronas-Samano et al. Frontiers in Aging Neuroscience
- Biomarkers for Early Diagnostic of Mild Cognitive Impairment in Type-2 Diabetes Patients: A Multicentre, Retrospective, Nested Case–Control Study
- (2016) Zhi-Peng Xu et al. EBioMedicine
- Assessment of Olfactory Function in MAPT-Associated Neurodegenerative Disease Reveals Odor-Identification Irreproducibility as a Non-Disease-Specific, General Characteristic of Olfactory Dysfunction
- (2016) Katerina Markopoulou et al. PLoS One
- Long-Lasting Metabolic Imbalance Related to Obesity Alters Olfactory Tissue Homeostasis and Impairs Olfactory-Driven Behaviors
- (2015) Marie-Christine Lacroix et al. CHEMICAL SENSES
- DPP-4 Inhibitor Linagliptin Attenuates Aβ-induced Cytotoxicity through Activation of AMPK in Neuronal Cells
- (2015) Edy Kornelius et al. CNS Neuroscience & Therapeutics
- Characterization and isolation of immature neurons of the adult mouse piriform cortex
- (2015) A. Rubio et al. Developmental Neurobiology
- Sitagliptin, a dipeptidyl peptidase-4 inhibitor, improves recognition memory, oxidative stress and hippocampal neurogenesis and upregulates key genes involved in cognitive decline
- (2015) V. A. Gault et al. DIABETES OBESITY & METABOLISM
- Olfactory dysfunction: its early temporal relationship and neural correlates in the pathogenesis of Alzheimer’s disease
- (2015) Mak Adam Daulatzai JOURNAL OF NEURAL TRANSMISSION
- Hippocampal insulin resistance and cognitive dysfunction
- (2015) Geert Jan Biessels et al. NATURE REVIEWS NEUROSCIENCE
- Loss of calbindin-D 28K is associated with the full range of tangle pathology within basal forebrain cholinergic neurons in Alzheimer's disease
- (2015) Saman S. Ahmadian et al. NEUROBIOLOGY OF AGING
- New neurons from old beliefs in the adult piriform cortex? A Commentary on: “Occurrence of new neurons in the piriform cortexâ€
- (2015) Juan Nacher et al. Frontiers in Neuroanatomy
- Potentials of incretin-based therapies in dementia and stroke in type 2 diabetes mellitus
- (2015) Onno N Groeneveld et al. Journal of Diabetes Investigation
- Connectivity of Pathology: The Olfactory System as a Model for Network-Driven Mechanisms of Alzheimer’s Disease Pathogenesis
- (2015) Katherine H. Franks et al. Frontiers in Aging Neuroscience
- Olfactory Dysfunction in Type 2 Diabetes Mellitus
- (2014) E. Gouveri et al. ANGIOLOGY
- Dipeptidyl peptidase-4 inhibition by Pterocarpus marsupium and Eugenia jambolana ameliorates streptozotocin induced Alzheimer's disease
- (2014) Jayasankar Kosaraju et al. BEHAVIOURAL BRAIN RESEARCH
- Interneurons, tau and amyloid-β in the piriform cortex in Alzheimer’s disease
- (2014) Daniel Saiz-Sanchez et al. Brain Structure & Function
- Crucial role of calbindin-D28k in the pathogenesis of Alzheimer’s disease mouse model
- (2014) S-Y Kook et al. CELL DEATH AND DIFFERENTIATION
- Relationship between olfactory dysfunction and cognitive impairment in elderly patients with type 2 diabetes mellitus
- (2014) Haruna Sanke et al. DIABETES RESEARCH AND CLINICAL PRACTICE
- A review of gliptins for 2014
- (2014) André J Scheen EXPERT OPINION ON PHARMACOTHERAPY
- Hyperlipidemic Diet Causes Loss of Olfactory Sensory Neurons, Reduces Olfactory Discrimination, and Disrupts Odor-Reversal Learning
- (2014) N. Thiebaud et al. JOURNAL OF NEUROSCIENCE
- Neuronal organization of olfactory bulb circuits
- (2014) Shin Nagayama et al. Frontiers in Neural Circuits
- The functional significance of newly born neurons integrated into olfactory bulb circuits
- (2014) Masayuki Sakamoto et al. Frontiers in Neuroscience
- Olfactory Assays for Mouse Models of Neurodegenerative Disease
- (2014) Andrew M. Lehmkuhl et al. Jove-Journal of Visualized Experiments
- Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety
- (2013) Carolyn F Deacon et al. EXPERT OPINION ON PHARMACOTHERAPY
- GalR3 activation promotes adult neural stem cell survival in response to a diabeticmilieu
- (2013) Shiva Mansouri et al. JOURNAL OF NEUROCHEMISTRY
- Saxagliptin: A dipeptidyl peptidase-4 inhibitor ameliorates streptozotocin induced Alzheimer's disease
- (2013) Jayasankar Kosaraju et al. NEUROPHARMACOLOGY
- Neurons and circuits for odor processing in the piriform cortex
- (2013) John M. Bekkers et al. TRENDS IN NEUROSCIENCES
- Diabetes drugs and neurological disorders: new views and therapeutic possibilities
- (2013) Cesare Patrone et al. Lancet Diabetes & Endocrinology
- Inhibitory Interneuron Deficit Links Altered Network Activity and Cognitive Dysfunction in Alzheimer Model
- (2012) Laure Verret et al. CELL
- The DPP-4 Inhibitor Linagliptin Counteracts Stroke in the Normal and Diabetic Mouse Brain: A Comparison With Glimepiride
- (2012) V. Darsalia et al. DIABETES
- Diabetes, hyperglycaemia, and acute ischaemic stroke
- (2012) Merel JA Luitse et al. LANCET NEUROLOGY
- Olfactory memory is impaired in a triple transgenic model of Alzheimer disease
- (2011) Tommaso Cassano et al. BEHAVIOURAL BRAIN RESEARCH
- Pituitary adenylate cyclase-activating polypeptide counteracts the impaired adult neural stem cell viability induced by palmitate
- (2011) Shiva Mansouri et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Properties of Doublecortin-(DCX)-Expressing Cells in the Piriform Cortex Compared to the Neurogenic Dentate Gyrus of Adult Mice
- (2011) Friederike Klempin et al. PLoS One
- Disruption of odour quality coding in piriform cortex mediates olfactory deficits in Alzheimer's disease
- (2010) W. Li et al. BRAIN
- Odor representations in mammalian cortical circuits
- (2010) Jeffry S Isaacson CURRENT OPINION IN NEUROBIOLOGY
- Accelerated Progression From Mild Cognitive Impairment to Dementia in People With Diabetes
- (2010) W. Xu et al. DIABETES
- Widespread deficits in adult neurogenesis precede plaque and tangle formation in the 3xTg mouse model of Alzheimer’s disease
- (2010) Laura K. Hamilton et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Diverse Patterns of Odor Representation by Neurons in the Anterior Piriform Cortex of Awake Mice
- (2010) C. Zhan et al. JOURNAL OF NEUROSCIENCE
- Central mechanisms of odour object perception
- (2010) Jay A. Gottfried NATURE REVIEWS NEUROSCIENCE
- Branching out: mechanisms of dendritic arborization
- (2010) Yuh-Nung Jan et al. NATURE REVIEWS NEUROSCIENCE
- Clinical significance of smell and taste disorders in patients with diabetes mellitus
- (2009) Asami Naka et al. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY
- Long-term inhibition of dipeptidyl peptidase-4 in Alzheimer’s prone mice
- (2009) Michele D’Amico et al. EXPERIMENTAL GERONTOLOGY
- Driving fast-spiking cells induces gamma rhythm and controls sensory responses
- (2009) Jessica A. Cardin et al. NATURE
- Diabetes, microvascular pathology and Alzheimer disease
- (2009) Raj N. Kalaria Nature Reviews Neurology
- Odor Representations in Olfactory Cortex: “Sparse” Coding, Global Inhibition, and Oscillations
- (2009) Cindy Poo et al. NEURON
- Impaired neurogenesis in adult type-2 diabetic rats
- (2008) Bradley T. Lang et al. BRAIN RESEARCH
- Cognitive Dysfunction and Diabetes Mellitus
- (2008) Christopher T. Kodl et al. ENDOCRINE REVIEWS
- Progressive impairment in olfactory working memory in a mouse model of Mild Cognitive Impairment
- (2008) Jared W. Young et al. NEUROBIOLOGY OF AGING
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