Fus1 KO Mouse As a Model of Oxidative Stress-Mediated Sporadic Alzheimer's Disease: Circadian Disruption and Long-Term Spatial and Olfactory Memory Impairments

Calretinin Interneurons are Early Targets of Extracellular Amyloid-β Pathology in PS1/AβPP Alzheimer Mice Hippocampus

(2017) David Baglietto-Vargas et al.   JOURNAL OF ALZHEIMERS DISEASE

The Alzheimer's Disease Mitochondrial Cascade Hypothesis

(2017) Russell H. Swerdlow et al.   JOURNAL OF ALZHEIMERS DISEASE

Toward more predictive genetic mouse models of Alzheimer's disease

(2016) Kristen D. Onos et al.   BRAIN RESEARCH BULLETIN

Sex and Genotype Differences in Odor Detection in the 3×Tg-AD and 5XFAD Mouse Models of Alzheimer’s Disease at 6 Months of Age

(2016) Kyle M. Roddick et al.   CHEMICAL SENSES

The Road to Reproducibility in Animal Research

(2016) Robert L Jilka   JOURNAL OF BONE AND MINERAL RESEARCH

The Habituation/Cross-Habituation Test Revisited: Guidance from Sniffing and Video Tracking

(2016) G. Coronas-Samano et al.   NEURAL PLASTICITY

Oxidative stress and redox regulation on hippocampal-dependent cognitive functions

(2015) Ting-Ting Huang et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Persistent hyperactivity and distinctive strategy features in the Morris water maze in 3xTg-AD mice at advanced stages of disease.

(2015) Raquel Baeta-Corral et al.   BEHAVIORAL NEUROSCIENCE

The case for rejecting the amyloid cascade hypothesis

(2015) Karl Herrup   NATURE NEUROSCIENCE

Increased fragmentation of sleep–wake cycles in the 5XFAD mouse model of Alzheimer’s disease

(2015) M. Sethi et al.   NEUROSCIENCE

A review on Alzheimer's disease pathophysiology and its management: an update

(2015) Anil Kumar et al.   Pharmacological Reports

Cellular oxidative stress response mediates radiosensitivity in Fus1-deficient mice

(2015) E M Yazlovitskaya et al.   Cell Death & Disease

Mitochondria, calcium, and tumor suppressor Fus1: At the crossroad of cancer, inflammation, and autoimmunity

(2015) Roman Uzhachenko et al.   Oncotarget

Connectivity of Pathology: The Olfactory System as a Model for Network-Driven Mechanisms of Alzheimer’s Disease Pathogenesis

(2015) Katherine H. Franks et al.   Frontiers in Aging Neuroscience

Depressive-Like Behavior Is Paired to Monoaminergic Alteration in a Murine Model of Alzheimer's Disease

(2015) A. Romano et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Alzheimer neurodegeneration, autophagy, and Abeta secretion: The ins and outs (comment on DOI 10.1002/bies.201400002)

(2014) Ralph A. Nixon   BIOESSAYS

Deficits in odor-guided behaviors in the transgenic 3xTg-AD female mouse model of Alzheimer׳s disease

(2014) G. Coronas-Sámano et al.   BRAIN RESEARCH

Sex differences in aging, life span and spontaneous tumorigenesis in 129/Sv mice neonatally exposed to metformin

(2014) Vladimir N Anisimov et al.   CELL CYCLE

Burrowing and nest building behavior as indicators of well-being in mice

(2014) Paulin Jirkof   JOURNAL OF NEUROSCIENCE METHODS

Evaluation of a Piezoelectric System as an Alternative to Electroencephalogram/ Electromyogram Recordings in Mouse Sleep Studies

(2014) Géraldine M. Mang et al.   SLEEP

Sleep and olfactory cortical plasticity

(2014) Dylan C. Barnes et al.   Frontiers in Behavioral Neuroscience

Longitudinal analysis of the behavioral phenotype in a novel transgenic rat model of early stages of Alzheimer's disease

(2014) Pablo Galeano et al.   Frontiers in Behavioral Neuroscience

Inconsistencies and Controversies Surrounding the Amyloid Hypothesis of Alzheimer's Disease

(2014) Gary P Morris et al.   Acta Neuropathologica Communications

Fus1/Tusc2 Is a Novel Regulator of Mitochondrial Calcium Handling, Ca2+-Coupled Mitochondrial Processes, and Ca2+-Dependent NFAT and NF-κB Pathways in CD4+ T Cells

(2013) Roman Uzhachenko et al.   ANTIOXIDANTS & REDOX SIGNALING

Duration and Specificity of Olfactory Nonassociative Memory

(2013) K. G. Freedman et al.   CHEMICAL SENSES

Autophagy failure in Alzheimer's disease and the role of defective lysosomal acidification

(2013) Devin M. Wolfe et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Loss of Mitochondrial Protein Fus1 Augments Host Resistance to Acinetobacter baumannii Infection

(2013) M. Indriati Hood et al.   INFECTION AND IMMUNITY

Why does Brain Metabolism not Favor Burning of Fatty Acids to Provide Energy? - Reflections on Disadvantages of the Use of Free Fatty Acids as Fuel for Brain

(2013) Peter Schönfeld et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Reproducibility of research and preclinical validation: problems and solutions

(2013) Lajos Pusztai et al.   Nature Reviews Clinical Oncology

Therapeutics of Alzheimer's disease: Past, present and future

(2013) R. Anand et al.   NEUROPHARMACOLOGY

A novel radioprotective function for the mitochondrial tumor suppressor protein Fus1

(2013) E M Yazlovitskaya et al.   Cell Death & Disease

Mitochondrion-Derived Reactive Oxygen Species Lead to Enhanced Amyloid Beta Formation

(2012) Kristina Leuner et al.   ANTIOXIDANTS & REDOX SIGNALING

Imaging evolutionarily conserved neural networks: Preferential activation of the olfactory system by food-related odor

(2012) Praveen Kulkarni et al.   BEHAVIOURAL BRAIN RESEARCH

Effects of aging and genotype on circadian rhythms, sleep, and clock gene expression in APPxPS1 knock-in mice, a model for Alzheimer's disease

(2012) Marilyn J. Duncan et al.   EXPERIMENTAL NEUROLOGY

Tumour suppressor Fus1 provides a molecular link between inflammatory response and mitochondrial homeostasis

(2012) Roman Uzhachenko et al.   JOURNAL OF PATHOLOGY

A Non-transgenic Mouse Model (icv-STZ Mouse) of Alzheimer’s Disease: Similarities to and Differences from the Transgenic Model (3xTg-AD Mouse)

(2012) Yanxing Chen et al.   MOLECULAR NEUROBIOLOGY

Mechanism of Oxidative Stress in Neurodegeneration

(2012) Sonia Gandhi et al.   Oxidative Medicine and Cellular Longevity

Sporadic dementia of Alzheimer's type induced by streptozotocin promotes anxiogenic behavior in mice

(2011) Simone Pinton et al.   BEHAVIOURAL BRAIN RESEARCH

S-allyl cysteine attenuates oxidative stress associated cognitive impairment and neurodegeneration in mouse model of streptozotocin-induced experimental dementia of Alzheimer's type

(2011) Hayate Javed et al.   BRAIN RESEARCH

Oxidative stress in synapse development and function

(2011) Valerie J. Milton et al.   Developmental Neurobiology

Resolving controversies on the path to Alzheimer's therapeutics

(2011) Dennis J Selkoe   NATURE MEDICINE

Anti-Aβ Therapeutics in Alzheimer's Disease: The Need for a Paradigm Shift

(2011) Todd E. Golde et al.   NEURON

Morris Water Maze Test for Learning and Memory Deficits in Alzheimer's Disease Model Mice

(2011) Kelley Bromley-Brits et al.   Jove-Journal of Visualized Experiments

Reactive Oxygen Species in the Regulation of Synaptic Plasticity and Memory

(2010) Cynthia A. Massaad et al.   ANTIOXIDANTS & REDOX SIGNALING

Age and gene overexpression interact to abolish nesting behavior in Tg2576 amyloid precursor protein (APP) mice

(2010) Daniel W. Wesson et al.   BEHAVIOURAL BRAIN RESEARCH

Correlating familial Alzheimer’s disease gene mutations with clinical phenotype

(2010) Natalie S Ryan et al.   Biomarkers in Medicine

Cytoprotective roles for autophagy

(2010) Kevin Moreau et al.   CURRENT OPINION IN CELL BIOLOGY

Olfactory Impairment in Presymptomatic Alzheimer's Disease

(2009) Robert S. Wilson et al.   Annals of the New York Academy of Sciences

Acetyl-CoA carboxylases 1 and 2 show distinct expression patterns in rats and humans and alterations in obesity and diabetes

(2009) Sebastian Kreuz et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Calretinin: Modulator of neuronal excitability

(2009) Aaron James Camp et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mechanisms of FUS1/TUSC2 deficiency in mesothelioma and its tumorigenic transcriptional effects

(2009) Alla V Ivanova et al.   Molecular Cancer

A Chronic Iron-Deficient/High-Manganese Diet in Rodents Results in Increased Brain Oxidative Stress and Behavioral Deficits in the Morris Water Maze

(2009) Vanessa A. Fitsanakis et al.   NEUROTOXICITY RESEARCH

Noradrenergic neuromodulation in the olfactory bulb modulates odor habituation and spontaneous discrimination.

(2008) Delphine Guérin et al.   BEHAVIORAL NEUROSCIENCE

Assessment of a non-invasive high-throughput classifier for behaviours associated with sleep and wake in mice

(2008) Kevin D Donohue et al.   Biomedical Engineering Online

Genetic aspects of Alzheimer disease

(2008) Thomas D Bird   GENETICS IN MEDICINE

Valproic acid inhibits Aβ production, neuritic plaque formation, and behavioral deficits in Alzheimer's disease mouse models

(2008) Hong Qing et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neurobiology of a Simple Memory

(2008) Donald A. Wilson et al.   JOURNAL OF NEUROPHYSIOLOGY

Distinct neural mechanisms mediate olfactory memory formation at different timescales

(2008) A. M. McNamara et al.   LEARNING & MEMORY

Intra-amygdala injections of CREB antisense impair inhibitory avoidance memory: Role of norepinephrine and acetylcholine

(2008) C. E. Canal et al.   LEARNING & MEMORY

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(2008) G Irvine et al.   MOLECULAR MEDICINE

Animal models of anxiety: do I need multiple tests?

(2008) André Ramos   TRENDS IN PHARMACOLOGICAL SCIENCES

Noradrenaline provides long-term protection to dopaminergic neurons by reducing oxidative stress

(2003) Jean-Denis Troadec et al.   JOURNAL OF NEUROCHEMISTRY