Macrophage Polarization in Chronic Inflammatory Diseases: Killers or Builders?

Adipogenic miR-27a in adipose tissue upregulates macrophage activation via inhibiting PPARγ of insulin resistance induced by high-fat diet-associated obesity

(2017) Fan Yao et al.   EXPERIMENTAL CELL RESEARCH

IL-6 Regulates M2 Polarization and Local Proliferation of Adipose Tissue Macrophages in Obesity

(2017) Julia Braune et al.   JOURNAL OF IMMUNOLOGY

Macrophages as Key Drivers of Cancer Progression and Metastasis

(2017) Sebastian R. Nielsen et al.   MEDIATORS OF INFLAMMATION

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Macrophage inducible C-type lectin (Mincle) recognizes glycosylated surface (S)-layer of the periodontal pathogen Tannerella forsythia

(2017) Sreedevi Chinthamani et al.   PLoS One

Targeting tumor associated macrophages: The new challenge for nanomedicine

(2017) Fernando Torres Andón et al.   SEMINARS IN IMMUNOLOGY

Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis

(2017) Ismail Sergin et al.   Nature Communications

CD206+ M2-like macrophages regulate systemic glucose metabolism by inhibiting proliferation of adipocyte progenitors

(2017) Allah Nawaz et al.   Nature Communications

The regulation of immune cells by Lactobacilli: a potential therapeutic target for anti-atherosclerosis therapy

(2017) Ya-Hui Ding et al.   Oncotarget

Promising landscape for regulating macrophage polarization: epigenetic viewpoint

(2017) Dexi Zhou et al.   Oncotarget

Redirecting tumor-associated macrophages to become tumoricidal effectors as a novel strategy for cancer therapy

(2017) Xiang Zheng et al.   Oncotarget

CD163+CD204+ tumor-associated macrophages contribute to T cell regulation via interleukin-10 and PD-L1 production in oral squamous cell carcinoma

(2017) Keigo Kubota et al.   Scientific Reports

Epigenetic Regulation of Monocyte and Macrophage Function

(2016) Marten A. Hoeksema et al.   ANTIOXIDANTS & REDOX SIGNALING

Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients

(2016) Niels Halama et al.   CANCER CELL

The Multifaceted Role of Perivascular Macrophages in Tumors

(2016) Claire E. Lewis et al.   CANCER CELL

HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance

(2016) Akiko Takikawa et al.   DIABETES

Monocytes and macrophages in tissue repair: Implications for immunoregenerative biomaterial design

(2016) Molly E Ogle et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

CD45 Phosphatase Inhibits STAT3 Transcription Factor Activity in Myeloid Cells and Promotes Tumor-Associated Macrophage Differentiation

(2016) Vinit Kumar et al.   IMMUNITY

Macrophages in Tissue Repair, Regeneration, and Fibrosis

(2016) Thomas A. Wynn et al.   IMMUNITY

MiR-130b promotes obesity associated adipose tissue inflammation and insulin resistance in diabetes mice through alleviating M2 macrophage polarization via repression of PPAR-γ

(2016) Min Zhang et al.   IMMUNOLOGY LETTERS

Accumulation of CD11c+CD163+Adipose Tissue Macrophages through Upregulation of Intracellular 11β-HSD1 in Human Obesity

(2016) Shotaro Nakajima et al.   JOURNAL OF IMMUNOLOGY

Bisphosphonates for cancer treatment: Mechanisms of action and lessons from clinical trials

(2016) Heleen H. Van Acker et al.   PHARMACOLOGY & THERAPEUTICS

M1- and M2-Type Macrophage Responses Are Predictive of Adverse Outcomes in Human Atherosclerosis

(2016) Monica de Gaetano et al.   Frontiers in Immunology

Hepatocellular carcinoma is accelerated by NASH involving M2 macrophage polarization mediated by hif-1αinduced IL-10

(2016) Aditya Ambade et al.   OncoImmunology

Unprimed, M1 and M2 Macrophages Differentially Interact with Porphyromonas gingivalis

(2016) Roselind S. Lam et al.   PLoS One

Factors regulating capillary remodeling in a reversible model of inflammatory corneal angiogenesis

(2016) Anthony Mukwaya et al.   Scientific Reports

Macrophages and Therapeutic Resistance in Cancer

(2015) Brian Ruffell et al.   CANCER CELL

Macrophage polarization in pathology

(2015) Antonio Sica et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Pleiotropic Benefits of Metformin: Macrophage Targeting Its Anti-inflammatory Mechanisms: Figure 1

(2015) Yuichi Hattori et al.   DIABETES

Macrophage dynamics are regulated by local macrophage proliferation and monocyte recruitment in injured pancreas

(2015) Naomi Van Gassen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Targeting of tumour-infiltrating macrophages via CCL2/CCR2 signalling as a therapeutic strategy against hepatocellular carcinoma

(2015) Xiaoguang Li et al.   GUT

Most Tissue-Resident Macrophages Except Microglia Are Derived from Fetal Hematopoietic Stem Cells

(2015) Jianpeng Sheng et al.   IMMUNITY

Macrophage polarization: the link between inflammation and related diseases

(2015) Samina Bashir et al.   INFLAMMATION RESEARCH

Epigenetic modifiers reduce inflammation and modulate macrophage phenotype during endotoxemia-induced acute lung injury

(2015) J. Thangavel et al.   JOURNAL OF CELL SCIENCE

Increased drug resistance in breast cancer by tumor-associated macrophages through IL-10/STAT3/bcl-2 signaling pathway

(2015) Cuixia Yang et al.   MEDICAL ONCOLOGY

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Concise Review: New Insights Into the Role of Macrophages in β-Cell Proliferation

(2015) Xiangwei Xiao et al.   Stem Cells Translational Medicine

Osteoimmunology: Major and Costimulatory Pathway Expression Associated with Chronic Inflammatory Induced Bone Loss

(2015) Tania N. Crotti et al.   Journal of Immunology Research

Ontogeny and Polarization of Macrophages in Inflammation: Blood Monocytes Versus Tissue Macrophages

(2015) Adwitia Dey et al.   Frontiers in Immunology

Heme oxygenase-1 and anti-inflammatory M2 macrophages

(2014) Yuji Naito et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Targeting Tumor-Associated Macrophages with Anti-CSF-1R Antibody Reveals a Strategy for Cancer Therapy

(2014) Carola H. Ries et al.   CANCER CELL

Macrophage Phenotypes and Their Modulation in Atherosclerosis

(2014) Federica De Paoli et al.   CIRCULATION JOURNAL

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Embryonic and Adult-Derived Resident Cardiac Macrophages Are Maintained through Distinct Mechanisms at Steady State and during Inflammation

(2014) Slava Epelman et al.   IMMUNITY

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Macrophage phenotypes in atherosclerosis

(2014) Sophie Colin et al.   IMMUNOLOGICAL REVIEWS

Transplantation of mesenchymal stem cells recruits trophic macrophages to induce pancreatic beta cell regeneration in diabetic mice

(2014) Xiaocang Cao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease

(2014) Un Jung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Polarization of Primary Human Monocytes by IFN-  Induces Chromatin Changes and Recruits RNA Pol II to the TNF-  Promoter

(2014) S. Garrett et al.   JOURNAL OF IMMUNOLOGY

Importance of TLR2 in Early Innate Immune Response to Acute Pulmonary Infection with Porphyromonas gingivalis in Mice

(2014) G. Hajishengallis et al.   JOURNAL OF IMMUNOLOGY

Regulation of Alternative Macrophage Activation by Galectin-3

(2014) A. C. MacKinnon et al.   JOURNAL OF IMMUNOLOGY

Macrophage Depletion AbatesPorphyromonas gingivalis–Induced Alveolar Bone Resorption in Mice

(2014) Roselind S. Lam et al.   JOURNAL OF IMMUNOLOGY

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

(2014) Elisa Gomez Perdiguero et al.   NATURE

Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis

(2014) Laura Bonapace et al.   NATURE

Macrophage subsets in atherosclerosis

(2014) Giulia Chinetti-Gbaguidi et al.   Nature Reviews Cardiology

Neutrophil Mobilization by Surface-Glycan Altered Th17-Skewing Bacteria Mitigates Periodontal Pathogen Persistence and Associated Alveolar Bone Loss

(2014) Rajendra P. Settem et al.   PLoS One

M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7

(2014) Xiangwei Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Real-Time Intravital Imaging Establishes Tumor-Associated Macrophages as the Extraskeletal Target of Bisphosphonate Action in Cancer

(2014) Simon Junankar et al.   Cancer Discovery

Periodontitis-activated monocytes/macrophages cause aortic inflammation

(2014) Shin-ichi Miyajima et al.   Scientific Reports

Role of tumor associated macrophages in tumor angiogenesis and lymphangiogenesis

(2014) Vladimir Riabov et al.   Frontiers in Physiology

Molecular Mechanisms That Influence the Macrophage M1–M2 Polarization Balance

(2014) Nan Wang et al.   Frontiers in Immunology

Metabolic Reprograming in Macrophage Polarization

(2014) Silvia Galván-Peña et al.   Frontiers in Immunology

Tumor-Associated Macrophages as Major Players in the Tumor Microenvironment

(2014) Theerawut Chanmee et al.   Cancers

Orchestration of Angiogenesis by Immune Cells

(2014) Antonino Bruno et al.   Frontiers in Oncology

Phenotypic Transitions of Macrophages Orchestrate Tissue Repair

(2013) Margaret L. Novak et al.   AMERICAN JOURNAL OF PATHOLOGY

Role of Macrophage Targeting in the Antitumor Activity of Trabectedin

(2013) Giovanni Germano et al.   CANCER CELL

Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity

(2013) Andrea Casazza et al.   CANCER CELL

CSF1R Signaling Blockade Stanches Tumor-Infiltrating Myeloid Cells and Improves the Efficacy of Radiotherapy in Prostate Cancer

(2013) J. Xu et al.   CANCER RESEARCH

A Phase I Study of an Agonist CD40 Monoclonal Antibody (CP-870,893) in Combination with Gemcitabine in Patients with Advanced Pancreatic Ductal Adenocarcinoma

(2013) G. L. Beatty et al.   CLINICAL CANCER RESEARCH

Do thiazolidinediones still have a role in treatment of type 2 diabetes mellitus?

(2013) A. Consoli et al.   DIABETES OBESITY & METABOLISM

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

Accumulation of M1-like macrophages in type 2 diabetic islets is followed by a systemic shift in macrophage polarization

(2013) H. Cucak et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Different responses to oxidized low-density lipoproteins in human polarized macrophages

(2013) Kuniaki Hirose et al.   Lipids in Health and Disease

A surface-exposed neuraminidase affects complement resistance and virulence of the oral spirochaeteTreponema denticola

(2013) Kurni Kurniyati et al.   MOLECULAR MICROBIOLOGY

Tissue-resident macrophages

(2013) Luke C Davies et al.   NATURE IMMUNOLOGY

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

CSF-1R inhibition alters macrophage polarization and blocks glioma progression

(2013) Stephanie M Pyonteck et al.   NATURE MEDICINE

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

(2013) Tony Jourdan et al.   NATURE MEDICINE

Adipose tissue inflammation in glucose metabolism

(2013) H. L. Kammoun et al.   REVIEWS IN ENDOCRINE & METABOLIC DISORDERS

Expression of M2-Polarized Macrophages is Associated with Poor Prognosis for Advanced Epithelial Ovarian Cancer

(2013) Chunyan Lan et al.   TECHNOLOGY IN CANCER RESEARCH & TREATMENT

The Role of Osteoimmunology in Periodontal Disease

(2013) Rayyan A. Kayal   Biomed Research International

Trabectedin

(2013) Paola Allavena et al.   OncoImmunology

Recruitment of monocytes/macrophages by tissue factor-mediated coagulation is essential for metastatic cell survival and premetastatic niche establishment in mice

(2012) A. M. Gil-Bernabe et al.   BLOOD

Saturated Fatty Acid and TLR Signaling Link β Cell Dysfunction and Islet Inflammation

(2012) Kosei Eguchi et al.   Cell Metabolism

A Novel Regulator of Macrophage Activation

(2012) Guoqing Zhuang et al.   CIRCULATION

TGF  Receptor Signaling Is Essential for Inflammation-Induced but Not  -Cell Workload-Induced  -Cell Proliferation

(2012) X. Xiao et al.   DIABETES

TIMP3 Overexpression in Macrophages Protects From Insulin Resistance, Adipose Inflammation, and Nonalcoholic Fatty Liver Disease in Mice

(2012) R. Menghini et al.   DIABETES

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

(2012) Simon Yona et al.   IMMUNITY

Identifying Functional MicroRNAs in Macrophages with Polarized Phenotypes

(2012) Joel W. Graff et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage-Specific TLR2 Signaling Mediates Pathogen-Induced TNF-Dependent Inflammatory Oral Bone Loss

(2012) G. Papadopoulos et al.   JOURNAL OF IMMUNOLOGY

Smooth muscle cells in human atherosclerosis: Proteomic profiling reveals differences in expression of Annexin A1 and mitochondrial proteins in carotid disease

(2012) Leena E. Viiri et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Tumor angiogenesis and lymphangiogenesis: Tumor/endothelial crosstalk and cellular/microenvironmental signaling mechanisms

(2012) Fausto Gueths Gomes et al.   LIFE SCIENCES

Alternatively Activated Macrophages in Types 1 and 2 Diabetes

(2012) Arlett Espinoza-Jiménez et al.   MEDIATORS OF INFLAMMATION

Treponema denticola chymotrypsin-like proteinase (CTLP) integrates spirochaetes within oral microbial communities

(2012) V. Cogoni et al.   MICROBIOLOGY-SGM

The keystone-pathogen hypothesis

(2012) George Hajishengallis et al.   NATURE REVIEWS MICROBIOLOGY

Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages

(2012) X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insights into the role of macrophage migration inhibitory factor in obesity and insulin resistance

(2012) Orla M. Finucane et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

JNK Expression by Macrophages Promotes Obesity-Induced Insulin Resistance and Inflammation

(2012) M. S. Han et al.   SCIENCE

Differential macrophage programming in the tumor microenvironment

(2012) Brian Ruffell et al.   TRENDS IN IMMUNOLOGY

Re-polarization of tumor-associated macrophages to pro-inflammatory M1 macrophages by microRNA-155

(2012) Xing Cai et al.   Journal of Molecular Cell Biology

Functional Role of Monocytes and Macrophages for the Inflammatory Response in Acute Liver Injury

(2012) Henning W. Zimmermann et al.   Frontiers in Physiology

Macrophage-Mediated Lymphangiogenesis: The Emerging Role of Macrophages as Lymphatic Endothelial Progenitors

(2012) Sophia Ran et al.   Cancers

Natural Innate and Adaptive Immunity to Cancer

(2011) Matthew D. Vesely et al.   Annual Review of Immunology

Targeting the ANG2/TIE2 Axis Inhibits Tumor Growth and Metastasis by Impairing Angiogenesis and Disabling Rebounds of Proangiogenic Myeloid Cells

(2011) Roberta Mazzieri et al.   CANCER CELL

Macrophages in the Pathogenesis of Atherosclerosis

(2011) Kathryn J. Moore et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Phenotypic modulation of macrophages in response to plaque lipids

(2011) Samantha Adamson et al.   CURRENT OPINION IN LIPIDOLOGY

Increased Macrophage Migration Into Adipose Tissue in Obese Mice

(2011) D. Y. Oh et al.   DIABETES

Epigenetic control of macrophage polarization

(2011) Osamu Takeuch et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

5-(4-Hydroxy-2,3,5-trimethylbenzylidene) thiazolidine-2,4-dione attenuates atherosclerosis possibly by reducing monocyte recruitment to the lesion

(2011) Jae-Hoon Choi et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Inflammation and wound healing: the role of the macrophage

(2011) Timothy J. Koh et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Oxidized phospholipid-induced inflammation is mediated by Toll-like receptor 2

(2011) Alexandra Kadl et al.   FREE RADICAL BIOLOGY AND MEDICINE

Histone deacetylase 3 is an epigenomic brake in macrophage alternative activation

(2011) S. E. Mullican et al.   GENES & DEVELOPMENT

Free Lipid A Isolated from Porphyromonas gingivalis Lipopolysaccharide Is Contaminated with Phosphorylated Dihydroceramide Lipids: Recovery in Diseased Dental Samples

(2011) Frank C. Nichols et al.   INFECTION AND IMMUNITY

Tumor-associated macrophages correlate with response to epidermal growth factor receptor-tyrosine kinase inhibitors in advanced non-small cell lung cancer

(2011) Fu-Tsai Chung et al.   INTERNATIONAL JOURNAL OF CANCER

Exenatide Exerts a Potent Antiinflammatory Effect

(2011) Ajay Chaudhuri et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Hematopoietic AMPK β1 reduces mouse adipose tissue macrophage inflammation and insulin resistance in obesity

(2011) Sandra Galic et al.   JOURNAL OF CLINICAL INVESTIGATION

Infection, Inflammation, and Bone Regeneration: a Paradoxical Relationship

(2011) M.V. Thomas et al.   JOURNAL OF DENTAL RESEARCH

Soluble vascular endothelial growth factor receptor-3 suppresses lymphangiogenesis and lymphatic metastasis in bladder cancer

(2011) Hanseul Yang et al.   Molecular Cancer

Atherosclerosis: current pathogenesis and therapeutic options

(2011) Christian Weber et al.   NATURE MEDICINE

Tumor-Associated Macrophages Recruit CCR6+ Regulatory T Cells and Promote the Development of Colorectal Cancer via Enhancing CCL20 Production in Mice

(2011) Jinlin Liu et al.   PLoS One

CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans

(2011) G. L. Beatty et al.   SCIENCE

Histone deacetylases as regulators of inflammation and immunity

(2011) Melanie R. Shakespear et al.   TRENDS IN IMMUNOLOGY

Role of IL-1β in type 2 diabetes

(2011) Charles A Dinarello et al.   Current Opinion in Endocrinology Diabetes and Obesity

Tumor-Associated Macrophages as Incessant Builders and Destroyers of the Cancer Stroma

(2011) Manuela Liguori et al.   Cancers

Macrophages, Inflammation, and Insulin Resistance

(2010) Jerrold M. Olefsky et al.   Annual Review of Physiology

Oxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: A crucial role for Krüppel-like factor 2

(2010) L.J.H. van Tits et al.   ATHEROSCLEROSIS

Macrophage Diversity Enhances Tumor Progression and Metastasis

(2010) Bin-Zhi Qian et al.   CELL

Atherogenic Lipids and Lipoproteins Trigger CD36-TLR2-Dependent Apoptosis in Macrophages Undergoing Endoplasmic Reticulum Stress

(2010) Tracie A. Seimon et al.   Cell Metabolism

Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

(2010) Alexandra Kadl et al.   CIRCULATION RESEARCH

The Interleukin 13 (IL-13) Pathway in Human Macrophages Is Modulated by MicroRNA-155 via Direct Targeting of Interleukin 13 Receptor α1 (IL13Rα1)

(2010) Rocio T. Martinez-Nunez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Macrophages heterogeneity in atherosclerosis - implications for therapy

(2010) Heather M. Wilson   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Potential of the Tannerella forsythia S-layer to Delay the Immune Response

(2010) G. Sekot et al.   JOURNAL OF DENTAL RESEARCH

Pivotal Advance: Avian colony-stimulating factor 1 (CSF-1 ), interleukin-34 (IL-34 ), and CSF-1 receptor genes and gene products

(2010) Valerie Garceau et al.   JOURNAL OF LEUKOCYTE BIOLOGY

NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals

(2010) Peter Duewell et al.   NATURE

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Tumor-Associated Macrophages and Survival in Classic Hodgkin's Lymphoma

(2010) Christian Steidl et al.   NEW ENGLAND JOURNAL OF MEDICINE

Development of Monocytes, Macrophages, and Dendritic Cells

(2010) F. Geissmann et al.   SCIENCE

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Circulating Monocytes Expressing CD31

(2009) Sun-Jin Kim et al.   AMERICAN JOURNAL OF PATHOLOGY

Tumor-associated macrophages: Effectors of angiogenesis and tumor progression

(2009) Seth B. Coffelt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Tie2-expressing monocytes (TEMs): Novel targets and vehicles of anticancer therapy?

(2009) Michele De Palma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Hematopoietic Cell-Specific Deletion of Toll-like Receptor 4 Ameliorates Hepatic and Adipose Tissue Insulin Resistance in High-Fat-Fed Mice

(2009) Maziyar Saberi et al.   Cell Metabolism

Regulation of JNK and p38 MAPK in the immune system: Signal integration, propagation and termination

(2009) Gonghua Huang et al.   CYTOKINE

Regulatory Mechanisms for Adipose Tissue M1 and M2 Macrophages in Diet-Induced Obese Mice

(2009) S. Fujisaka et al.   DIABETES

The RgpA-Kgp Proteinase-Adhesin Complexes of Porphyromonas gingivalis Inactivate the Th2 Cytokines Interleukin-4 and Interleukin-5

(2009) V. Tam et al.   INFECTION AND IMMUNITY

Macrophage-derived human resistin exacerbates adipose tissue inflammation and insulin resistance in mice

(2009) Mohammed Qatanani et al.   JOURNAL OF CLINICAL INVESTIGATION

Differential Role for c-Rel and C/EBP /  in TLR-Mediated Induction of Proinflammatory Cytokines

(2009) Y.-C. Lu et al.   JOURNAL OF IMMUNOLOGY

Function of C/EBPδ in a regulatory circuit that discriminates between transient and persistent TLR4-induced signals

(2009) Vladimir Litvak et al.   NATURE IMMUNOLOGY

In Vivo Analysis of Dendritic Cell Development and Homeostasis

(2009) K. Liu et al.   SCIENCE

Alternative Activation of Macrophages: An Immunologic Functional Perspective

(2008) Fernando O. Martinez et al.   Annual Review of Immunology

Macrophage-Derived SPARC Bridges Tumor Cell-Extracellular Matrix Interactions toward Metastasis

(2008) Sabina Sangaletti et al.   CANCER RESEARCH

Alternative M2 Activation of Kupffer Cells by PPARδ Ameliorates Obesity-Induced Insulin Resistance

(2008) Justin I. Odegaard et al.   Cell Metabolism

PPARδ/β: The Lobbyist Switching Macrophage Allegiance in Favor of Metabolism

(2008) Béatrice Desvergne   Cell Metabolism

Sphingosine-1-Phosphate Induces an Antiinflammatory Phenotype in Macrophages

(2008) Jeniter E. Hughes et al.   CIRCULATION RESEARCH

Macrophages Generate Reactive Oxygen Species in Response to Minimally Oxidized Low-Density Lipoprotein

(2008) Yun Soo Bae et al.   CIRCULATION RESEARCH

Exendin-4 Protects  -Cells From Interleukin-1 -Induced Apoptosis by Interfering With the c-Jun NH2-Terminal Kinase Pathway

(2008) M. Ferdaoussi et al.   DIABETES

Increased density of tumor-associated macrophages is associated with decreased survival in advanced thyroid cancer

(2008) M. Ryder et al.   ENDOCRINE-RELATED CANCER

The Adipocyte as an Endocrine Cell

(2008) Nils Halberg et al.   ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA

Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells

(2008) Ilaria Marigo et al.   IMMUNOLOGICAL REVIEWS

Role of CC Chemokine Receptor 2 in Bone Marrow Cells in the Recruitment of Macrophages into Obese Adipose Tissue

(2008) Ayaka Ito et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages

(2008) Jose Rafael Sierra et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE

Stromal Gene Signatures in Large-B-Cell Lymphomas

(2008) G. Lenz et al.   NEW ENGLAND JOURNAL OF MEDICINE

Mechanisms of macrophage activation in obesity-induced insulin resistance

(2008) Justin I Odegaard et al.   Nature clinical practice. Endocrinology & metabolism