Risk Assessment and Risk Minimization in Nanomedicine: A Need for Predictive, Alternative, and 3Rs Strategies

Physico-chemical properties of manufactured nanomaterials - Characterisation and relevant methods. An outlook based on the OECD Testing Programme

(2018) Kirsten Rasmussen et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Immunotoxicity, genotoxicity and epigenetic toxicity of nanomaterials: New strategies for toxicity testing?

(2017) Maria Dusinska et al.   FOOD AND CHEMICAL TOXICOLOGY

Current Knowledge on the Use of Computational Toxicology in Hazard Assessment of Metallic Engineered Nanomaterials

(2017) Guangchao Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Aligning nanotoxicology with the 3Rs: What is needed to realise the short, medium and long-term opportunities?

(2017) Natalie Burden et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Role of omics techniques in the toxicity testing of nanoparticles

(2017) Eleonore Fröhlich   JOURNAL OF NANOBIOTECHNOLOGY

Emerging metrology for high-throughput nanomaterial genotoxicology

(2016) Bryant C. Nelson et al.   MUTAGENESIS

Alternative Testing Strategies for Nanomaterials: State of the Science and Considerations for Risk Analysis

(2016) J. A. Shatkin et al.   RISK ANALYSIS

Recent advances, and unresolved issues, in the application of computational modelling to the prediction of the biological effects of nanomaterials

(2016) David A. Winkler   TOXICOLOGY AND APPLIED PHARMACOLOGY

Stem Cell Tracking with Nanoparticles for Regenerative Medicine Purposes: An Overview

(2016) Lisa Accomasso et al.   Stem Cells International

Integrated Testing Strategy (ITS) – Opportunities to better use existing data and guide future testing in toxicology

(2016) Joanna Jaworska   ALTEX-Alternatives to Animal Experimentation

High-content analysis for drug delivery and nanoparticle applications

(2015) David J. Brayden et al.   DRUG DISCOVERY TODAY

Towards an alternative testing strategy for nanomaterials used in nanomedicine: Lessons from NanoTEST

(2015) M. Dusinska et al.   Nanotoxicology

Defining Nano, Nanotechnology and Nanomedicine: Why Should It Matter?

(2015) Priya Satalkar et al.   SCIENCE AND ENGINEERING ETHICS

Handling Worker and Third-Party Exposures to Nanotherapeutics during Clinical Trials

(2015) Gurumurthy Ramachandran et al.   JOURNAL OF LAW MEDICINE & ETHICS

Nanomedicine First-in-Human Research: Challenges for Informed Consent

(2015) Nancy M. P. King   JOURNAL OF LAW MEDICINE & ETHICS

Concepts of Risk in Nanomedicine Research

(2015) Linda F. Hogle   JOURNAL OF LAW MEDICINE & ETHICS

Nanotherapeutics in the EU: an overview on current state and future directions

(2014) Ivan Pepic et al.   International Journal of Nanomedicine

ITS-NANO - Prioritising nanosafety research to develop a stakeholder driven intelligent testing strategy

(2014) Vicki Stone et al.   Particle and Fibre Toxicology

A Multi-Stakeholder Perspective on the Use of Alternative Test Strategies for Nanomaterial Safety Assessment

(2013) Andre E. Nel et al.   ACS Nano

Inflammatory findings on species extrapolations: humans are definitely no 70-kg mice

(2013) Marcel Leist et al.   ARCHIVES OF TOXICOLOGY

Implementation of alternative test strategies for the safety assessment of engineered nanomaterials

(2013) A. E. Nel   JOURNAL OF INTERNAL MEDICINE

Therapeutic nanoparticles in clinics and under clinical evaluation

(2013) Catherine A Schütz et al.   Nanomedicine

Biological impact assessment of nanomaterial used in nanomedicine. Introduction to the NanoTEST project

(2013) Lucienne Juillerat-Jeanneret et al.   Nanotoxicology

Toxicity evaluation of engineered nanoparticles for medical applications using pulmonary epithelial cells

(2013) Rina Guadagnini et al.   Nanotoxicology

Concern-driven integrated approaches to nanomaterial testing and assessment – report of the NanoSafety Cluster Working Group 10

(2013) Agnes G. Oomen et al.   Nanotoxicology

Nanomaterial Toxicity Testing in the 21st Century: Use of a Predictive Toxicological Approach and High-Throughput Screening

(2012) Andre Nel et al.   ACCOUNTS OF CHEMICAL RESEARCH

Use of Metal Oxide Nanoparticle Band Gap To Develop a Predictive Paradigm for Oxidative Stress and Acute Pulmonary Inflammation

(2012) Haiyuan Zhang et al.   ACS Nano

The big picture on nanomedicine: the state of investigational and approved nanomedicine products

(2012) Michael L. Etheridge et al.   Nanomedicine-Nanotechnology Biology and Medicine

A weight of evidence approach for hazard screening of engineered nanomaterials

(2012) Danail R. Hristozov et al.   Nanotoxicology

Theranostic Nanomedicine

(2011) Twan Lammers et al.   ACCOUNTS OF CHEMICAL RESEARCH

Nanomedicine(s) under the Microscope

(2011) Ruth Duncan et al.   MOLECULAR PHARMACEUTICS

Predicting Harms and Benefits in Translational Trials: Ethics, Evidence, and Uncertainty

(2011) Jonathan Kimmelman et al.   PLOS MEDICINE

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

The Coming Era of Nanomedicine

(2009) Fritz Allhoff   AMERICAN JOURNAL OF BIOETHICS

Nanomedicine and Society

(2009) M Ferrari et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology

(2009) G. Oberdörster   JOURNAL OF INTERNAL MEDICINE

Toxicology for the twenty-first century

(2009) Thomas Hartung   NATURE