Role of omics techniques in the toxicity testing of nanoparticles

The timeline of corona formation around silica nanocarriers highlights the role of the protein interactome

(2017) Cédric Pisani et al.   Nanoscale

Changes in DNA Methylation in Mouse Lungs after a Single Intra-Tracheal Administration of Nanomaterials

(2017) Ali M. Tabish et al.   PLoS One

Epigenetic modulation upon exposure of lung fibroblasts to TiO2 and ZnO nanoparticles: alterations in DNA methylation

(2016) Deepti Dileep Deobagkar et al.   International Journal of Nanomedicine

Cytotoxic and Proinflammatory Effects of Metal-Based Nanoparticles on THP-1 Monocytes Characterized by Combined Proteomics Approaches

(2016) Nataliya K. Tarasova et al.   JOURNAL OF PROTEOME RESEARCH

Molecular responses of alveolar epithelial A549 cells to chronic exposure to titanium dioxide nanoparticles: A proteomic view

(2016) Lucie Armand et al.   Journal of Proteomics

A combined proteomic and targeted analysis unravels new toxic mechanisms for zinc oxide nanoparticles in macrophages

(2016) Catherine Aude-Garcia et al.   Journal of Proteomics

Toxicogenomics analysis of mouse lung responses following exposure to titanium dioxide nanomaterials reveal their disease potential at high doses

(2016) Luna Rahman et al.   MUTAGENESIS

Characterization of in vitro genotoxic, cytotoxic and transcriptomic responses following exposures to amorphous silica of different sizes

(2016) Nathalie Decan et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Different responses of Caco-2 and MCF-7 cells to silver nanoparticles are based on highly similar mechanisms of action

(2016) Meike van der Zande et al.   Nanotoxicology

A combined proteomics and metabolomics approach to assess the effects of gold nanoparticlesin vitro

(2016) Sabrina Gioria et al.   Nanotoxicology

Metabolomics of silver nanoparticles toxicity in HaCaT cells: structure–activity relationships and role of ionic silver and oxidative stress

(2016) Joana Carrola et al.   Nanotoxicology

Integrative functional transcriptomic analyses implicate specific molecular pathways in pulmonary toxicity from exposure to aluminum oxide nanoparticles

(2016) Xiaobo Li et al.   Nanotoxicology

NMR-based metabolomics to determine acute inhalation effects of nano- and fine-sized ZnO particles in the rat lung

(2016) Sheng-Han Lee et al.   Nanotoxicology

Influence of agglomeration and specific lung lining lipid/protein interaction on short-term inhalation toxicity

(2016) Wendel Wohlleben et al.   Nanotoxicology

Protein adsorption is required for stealth effect of poly(ethylene glycol)- and poly(phosphoester)-coated nanocarriers

(2016) Susanne Schöttler et al.   Nature Nanotechnology

Integrative analysis of genes and miRNA alterations in human embryonic stem cells-derived neural cells after exposure to silver nanoparticles

(2016) Jung-Hwa Oh et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

GC-MS metabolomics analysis of mesenchymal stem cells treated with copper oxide nanoparticles

(2016) Antonio Murgia et al.   TOXICOLOGY MECHANISMS AND METHODS

GC-MS metabolomics analysis of mesenchymal stem cells treated with copper oxide nanoparticles

(2016) Antonio Murgia et al.   TOXICOLOGY MECHANISMS AND METHODS

The impact of species and cell type on the nanosafety profile of iron oxide nanoparticles in neural cells

(2016) Freya Joris et al.   JOURNAL OF NANOBIOTECHNOLOGY

Quantitative Profiling of Protein S-Glutathionylation Reveals Redox-Dependent Regulation of Macrophage Function during Nanoparticle-Induced Oxidative Stress

(2015) Jicheng Duan et al.   ACS Nano

Translating extracellular microRNA into clinical biomarkers for drug-induced toxicity: from high-throughput profiling to validation

(2015) Wenjun Wang et al.   Biomarkers in Medicine

Altered protein expression profile associated with phenotypic changes in lung fibroblasts co-cultured with gold nanoparticle-treated small airway epithelial cells

(2015) Cheng-Teng Ng et al.   BIOMATERIALS

Silver nanoparticle-induced hemoglobin decrease involves alteration of histone 3 methylation status

(2015) Yi Qian et al.   BIOMATERIALS

Gold nanoparticles with different charge and moiety induce differential cell response on mesenchymal stem cell osteogenesis

(2015) Jia'En Jasmine Li et al.   BIOMATERIALS

High-throughput, quantitative assessment of the effects of low-dose silica nanoparticles on lung cells: grasping complex toxicity with a great depth of field

(2015) Cédric Pisani et al.   BMC GENOMICS

Toxicogenomic responses of human liver HepG2 cells to silver nanoparticles

(2015) Saura C. Sahu et al.   JOURNAL OF APPLIED TOXICOLOGY

Comparison of pulmonary inflammatory responses following intratracheal instillation and inhalation of nanoparticles

(2015) Yasuo Morimoto et al.   Nanotoxicology

Extensive temporal transcriptome and microRNA analyses identify molecular mechanisms underlying mitochondrial dysfunction induced by multi-walled carbon nanotubes in human lung cells

(2015) Penny Nymark et al.   Nanotoxicology

In vivoepigenetic effects induced by engineered nanomaterials: A case study of copper oxide and laser printer-emitted engineered nanoparticles

(2015) Xiaoyan Lu et al.   Nanotoxicology

Copper oxide nanoparticle toxicity profiling using untargeted metabolomics

(2015) Matthew S. P. Boyles et al.   Particle and Fibre Toxicology

An acetyl-L-carnitine switch on mitochondrial dysfunction and rescue in the metabolomics study on aluminum oxide nanoparticles

(2015) Xiaobo Li et al.   Particle and Fibre Toxicology

Effects of silver nanoparticles and ions on a co-culture model for the gastrointestinal epithelium

(2015) Anastasia Georgantzopoulou et al.   Particle and Fibre Toxicology

Meta-analysis of transcriptomic responses as a means to identify pulmonary disease outcomes for engineered nanomaterials

(2015) Jake Nikota et al.   Particle and Fibre Toxicology

Proteomics Analysis Reveals Distinct Corona Composition on Magnetic Nanoparticles with Different Surface Coatings: Implications for Interactions with Primary Human Macrophages

(2015) Carmen Vogt et al.   PLoS One

Changes in Caco-2 cells transcriptome profiles upon exposure to gold nanoparticles

(2015) Edyta Bajak et al.   TOXICOLOGY LETTERS

Cytotoxicity, genotoxicity and alteration of cellular antioxidant enzymes in silver nanoparticles exposed CHO cells

(2015) Kumud Kant Awasthi et al.   RSC Advances

Effects of an 11-nm DMSA-coated iron nanoparticle on the gene expression profile of two human cell lines, THP-1 and HepG2

(2015) Ling Zhang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Web Resources for Mass Spectrometry-based Proteomics

(2015) Tao Chen et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Comprehensive Evaluation of microRNA Expression Profiling Reveals the Neural Signaling Specific Cytotoxicity of Superparamagnetic Iron Oxide Nanoparticles (SPIONs) through N-Methyl-D-Aspartate Receptor

(2015) Bo Sun et al.   PLoS One

Comparative Proteomic Analysis of the Molecular Responses of Mouse Macrophages to Titanium Dioxide and Copper Oxide Nanoparticles Unravels Some Toxic Mechanisms for Copper Oxide Nanoparticles in Macrophages

(2015) Sarah Triboulet et al.   PLoS One

Insights into the Cellular Response Triggered by Silver Nanoparticles Using Quantitative Proteomics

(2014) Thiago Verano-Braga et al.   ACS Nano

PEGylation of ORMOSIL nanoparticles differently modulates the in vitro toxicity toward human lung cells

(2014) Francesca Moret et al.   ARCHIVES OF TOXICOLOGY

Toxicity evaluation of manufactured CeO2 nanoparticles before and after alteration: combined physicochemical and whole-genome expression analysis in Caco-2 cells

(2014) Matthieu Fisichella et al.   BMC GENOMICS

Transcriptional profiling identifies physicochemical properties of nanomaterials that are determinants of the in vivo pulmonary response

(2014) Sabina Halappanavar et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Multiple evidence strands suggest that there may be as few as 19 000 human protein-coding genes

(2014) Iakes Ezkurdia et al.   HUMAN MOLECULAR GENETICS

Effects of 2,3-Dimercaptosuccinic Acid-Coated Fe3O4 Nanoparticles on Genes in Two Mouse Cell Lines

(2014) Yingxun Liu et al.   Journal of Biomedical Nanotechnology

Toxicity of Silver Nanoparticles to Human Dermal Fibroblasts on MicroRNA Level

(2014) Yan Huang et al.   Journal of Biomedical Nanotechnology

Genotoxicity of titanium dioxide nanoparticles

(2014) Tao Chen et al.   JOURNAL OF FOOD AND DRUG ANALYSIS

Nano-sized titanium dioxide-induced splenic toxicity: A biological pathway explored using microarray technology

(2014) Lei Sheng et al.   JOURNAL OF HAZARDOUS MATERIALS

Phagocytosis of nano-sized titanium dioxide triggers changes in protein acetylation

(2014) Jukka Sund et al.   Journal of Proteomics

Toxic responses in rat embryonic cells to silver nanoparticles and released silver ions as analyzed via gene expression profiles and transmission electron microscopy

(2014) Liming Xu et al.   Nanotoxicology

Adenosine monophosphate is elevated in the bronchoalveolar lavage fluid of mice with acute respiratory toxicity induced by nanoparticles with high surface hydrophobicity

(2014) Lea Ann Dailey et al.   Nanotoxicology

Proteomic Analysis of Cellular Response Induced by Multi-Walled Carbon Nanotubes Exposure in A549 Cells

(2014) Li Ju et al.   PLoS One

High Content Analysis Provides Mechanistic Insights on the Pathways of Toxicity Induced by Amine-Modified Polystyrene Nanoparticles

(2014) Sergio Anguissola et al.   PLoS One

SILAC-Based Quantitative Proteomic Analysis of Human Lung Cell Response to Copper Oxide Nanoparticles

(2014) Mariola J. Edelmann et al.   PLoS One

Changes in protein expression in rat bronchoalveolar lavage fluid after exposure to zinc oxide nanoparticles: an iTRAQ proteomic approach

(2014) Yu-Min Juang et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Carboxylated Short Single-Walled Carbon Nanotubes But Not Plain and Multi-Walled Short Carbon Nanotubes Show in vitro Genotoxicity

(2014) Maria Mrakovcic et al.   TOXICOLOGICAL SCIENCES

Use of whole genome expression analysis in the toxicity screening of nanoparticles

(2014) Eleonore Fröhlich et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A proteomic approach to investigate AuNPs effects in Balb/3T3 cells

(2014) Sabrina Gioria et al.   TOXICOLOGY LETTERS

Integrated mRNA and micro RNA profiling reveals epigenetic mechanism of differential sensitivity of Jurkat T cells to AgNPs and Ag ions

(2014) Hyun-Jeong Eom et al.   TOXICOLOGY LETTERS

Metabolomic analysis on the toxicological effects of TiO2nanoparticles in mouse fibroblast cells: from the perspective of perturbations in amino acid metabolism

(2014) Yang Bo et al.   TOXICOLOGY MECHANISMS AND METHODS

Systems toxicology

(2014) Thomas HArtung   ALTEX-Alternatives to Animal Experimentation

Metabolomics in toxicology and preclinical research

(2014) Tzutzuy Ramirez   ALTEX-Alternatives to Animal Experimentation

Altered Gene Transcription in Human Cells Treated with Ludox® Silica Nanoparticles

(2014) Caterina Fede et al.   International Journal of Environmental Research and Public Health

Nano-sized and micro-sized polystyrene particles affect phagocyte function

(2013) B. Prietl et al.   CELL BIOLOGY AND TOXICOLOGY

Protein Analysis by Shotgun/Bottom-up Proteomics

(2013) Yaoyang Zhang et al.   CHEMICAL REVIEWS

Cellular Targets and Mechanisms in the Cytotoxic Action of Non-biodegradable Engineered Nanoparticles

(2013) Eleonore Fröhlich   CURRENT DRUG METABOLISM

MicroRNA Expression in Response to Controlled Exposure to Diesel Exhaust: Attenuation by the Antioxidant N -Acetylcysteine in a Randomized Crossover Study

(2013) Masatsugu Yamamoto et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Cytotoxicity and Genotoxicity of Copper Oxide Nanoparticles in Human Skin Keratinocytes Cells

(2013) Saud Alarifi et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Molecular Responses of Mouse Macrophages to Copper and Copper Oxide Nanoparticles Inferred from Proteomic Analyses

(2013) Sarah Triboulet et al.   MOLECULAR & CELLULAR PROTEOMICS

Understanding the metabolic fate and assessing the biosafety of MnO nanoparticles by metabonomic analysis

(2013) Jinquan Li et al.   NANOTECHNOLOGY

Serum protein identification and quantification of the corona of 5, 15 and 80 nm gold nanoparticles

(2013) Martin Schäffler et al.   NANOTECHNOLOGY

Iron oxide nanoparticle toxicity testing using high-throughput analysis and high-content imaging

(2013) Georgina Harris et al.   Nanotoxicology

Three human cell types respond to multi-walled carbon nanotubes and titanium dioxide nanobelts with cell-specific transcriptomic and proteomic expression patterns

(2013) Susan C. Tilton et al.   Nanotoxicology

Surface coatings of ZnO nanoparticles mitigate differentially a host of transcriptional, protein and signalling responses in primary human olfactory cells

(2013) Megan J Osmond-McLeod et al.   Particle and Fibre Toxicology

Effect of Labeling with Iron Oxide Particles or Nanodiamonds on the Functionality of Adipose-Derived Mesenchymal Stem Cells

(2013) Sinead P. Blaber et al.   PLoS One

Silver Nanoparticle Protein Corona Composition in Cell Culture Media

(2013) Jonathan H. Shannahan et al.   PLoS One

Elucidation of Toxicity Pathways in Lung Epithelial Cells Induced by Silicon Dioxide Nanoparticles

(2013) Odu Okoturo-Evans et al.   PLoS One

Gene Expression Profiling of Immune-Competent Human Cells Exposed to Engineered Zinc Oxide or Titanium Dioxide Nanoparticles

(2013) Soile Tuomela et al.   PLoS One

Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation

(2013) Mainul Husain et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Dose-dependent genotoxicity of copper oxide nanoparticles stimulated by reactive oxygen species in human lung epithelial cells

(2013) Mohammad Javed Akhtar et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Gene expression profiling of kidneys from Sprague–Dawley rats following 12-week inhalation exposure to silver nanoparticles

(2013) Mi Sook Dong et al.   TOXICOLOGY MECHANISMS AND METHODS

Nanoparticle vaccines

(2013) Liang Zhao et al.   VACCINE

Emerging Techniques in Proteomics for Probing Nano–Bio Interactions

(2012) Zon W. Lai et al.   ACS Nano

The effects of sub-lethal concentrations of silver nanoparticles on inflammatory and stress genes in human macrophages using cDNA microarray analysis

(2012) Dae-Hyoun Lim et al.   BIOMATERIALS

Cancer Genetics and Epigenetics: Two Sides of the Same Coin?

(2012) Jueng Soo You et al.   CANCER CELL

Silver nanoparticle-induced mutations and oxidative stress in mouse lymphoma cells

(2012) Nan Mei et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles

(2012) Eleonore Fröhlich   International Journal of Nanomedicine

Metabolic profiling reveals disorder of carbohydrate metabolism in mouse fibroblast cells induced by titanium dioxide nanoparticles

(2012) Chengyu Jin et al.   JOURNAL OF APPLIED TOXICOLOGY

Proteomic Analysis of Molecular Biocompatibility of Gold Nanoparticles to Human Dermal Fibroblasts-Fetal

(2012) Yinghua Qu et al.   Journal of Biomedical Nanotechnology

Metal nanoparticle-induced micronuclei and oxidative DNA damage in mice

(2012) Ming-Fen Song et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Ovarian dysfunction and gene-expressed characteristics of female mice caused by long-term exposure to titanium dioxide nanoparticles

(2012) Guodong Gao et al.   JOURNAL OF HAZARDOUS MATERIALS

Proteomic analysis of hepatotoxicity induced by titanium nanoparticles in mouse liver

(2012) Yu-Mi Jeon et al.   Journal of the Korean Society for Applied Biological Chemistry

Effects of zinc oxide nanoparticles on gene expression profile in human keratinocytes

(2012) Seung Ho Lee et al.   Molecular & Cellular Toxicology

Characterization of carbon nanotube protein corona by using quantitative proteomics

(2012) Xiaoning Cai et al.   Nanomedicine-Nanotechnology Biology and Medicine

Combination of small size and carboxyl functionalisation causes cytotoxicity of short carbon nanotubes

(2012) Eleonore Fröhlich et al.   Nanotoxicology

Gene Expression in Liver Injury Caused by Long-term Exposure to Titanium Dioxide Nanoparticles in Mice

(2012) Yaling Cui et al.   TOXICOLOGICAL SCIENCES

Global Gene Expression Profiling of Human Lung Epithelial Cells After Exposure to Nanosilver

(2012) Rasmus Foldbjerg et al.   TOXICOLOGICAL SCIENCES

Mechanistic Toxicity Evaluation of Uncoated and PEGylated Single-Walled Carbon Nanotubes in Neuronal PC12 Cells

(2011) Yongbin Zhang et al.   ACS Nano

Molecular Responses of Human Lung Epithelial Cells to the Toxicity of Copper Oxide Nanoparticles Inferred from Whole Genome Expression Analysis

(2011) Nobutaka Hanagata et al.   ACS Nano

Identification of the Nanogold Particle-Induced Endoplasmic Reticulum Stress by Omic Techniques and Systems Biology Analysis

(2011) Yen-Yin Tsai et al.   ACS Nano

Toxicity Evaluations of Superparamagnetic Iron Oxide Nanoparticles: Cell “Vision” versus Physicochemical Properties of Nanoparticles

(2011) Morteza Mahmoudi et al.   ACS Nano

Characterization of Translocation of Silver Nanoparticles and Effects on Whole-Genome Gene Expression Using an In Vitro Intestinal Epithelium Coculture Model

(2011) Hans Bouwmeester et al.   ACS Nano

Toxicoproteomic identification of TiO2nanoparticle-induced protein expression changes in mouse brain

(2011) Yu-Mi Jeon et al.   Animal Cells and Systems

Integrated pathway-level analysis of transcriptomics and metabolomics data with IMPaLA

(2011) Atanas Kamburov et al.   BIOINFORMATICS

Genomic instability of gold nanoparticle treated human lung fibroblast cells

(2011) Jasmine J. Li et al.   BIOMATERIALS

Evaluation of Toxicity and Gene Expression Changes Triggered by Oxide Nanoparticles

(2011) Pooja Dua et al.   BULLETIN OF THE KOREAN CHEMICAL SOCIETY

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Gene expression profiling of nephrotoxicity from copper nanoparticles in rats after repeated oral administration

(2011) MingYang Liao et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Genomic Analysis of Cytotoxicity Response to Nanosilver in Human Dermal Fibroblasts

(2011) Jingwu Ma et al.   Journal of Biomedical Nanotechnology

Proteomic analysis of early response lymph node proteins in mice treated with titanium dioxide nanoparticles

(2011) Yuan Gao et al.   Journal of Proteomics

Physical−Chemical Aspects of Protein Corona: Relevance toin Vitroandin VivoBiological Impacts of Nanoparticles

(2011) Marco P. Monopoli et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Responses of human cells to ZnO nanoparticles: a gene transcription study

(2011) Philip J. Moos et al.   Metallomics

The effects of TiO2 nanoparticles on the protein expression in mouse lung

(2011) Yu-Mi Jeon et al.   Molecular & Cellular Toxicology

No time to lose—high throughput screening to assess nanomaterial safety

(2011) R. Damoiseaux et al.   Nanoscale

Differential toxicity of copper (II) oxide nanoparticles of similar hydrodynamic diameter on human differentiated intestinal Caco-2 cell monolayers is correlated in part to copper release and shape

(2011) Jean-Pascal Piret et al.   Nanotoxicology

Maternal inhalation of surface-coated nanosized titanium dioxide (UV-Titan) in C57BL/6 mice: effects in prenatally exposed offspring on hepatic DNA damage and gene expression

(2011) Petra Jackson et al.   Nanotoxicology

Cytotoxity of nanoparticles is influenced by size, proliferation and embryonic origin of the cells used for testing

(2011) Eleonore Fröhlich et al.   Nanotoxicology

Effects of copper nanoparticle exposure on host defense in a murine pulmonary infection model

(2011) Jong Sung Kim et al.   Particle and Fibre Toxicology

Proteome profiling reveals potential toxicity and detoxification pathways following exposure of BEAS-2B cells to engineered nanoparticle titanium dioxide

(2011) Yue Ge et al.   PROTEOMICS

Cytotoxicity of single-walled carbon nanotubes on human hepatoma HepG2 cells: An iTRAQ-coupled 2D LC–MS/MS proteome analysis

(2011) Jifeng Yuan et al.   TOXICOLOGY IN VITRO

Toxicity of Silver Nanoparticles as Assessed by Global Gene Expression Analysis

(2011) Liming Xu et al.   Materials Express

Use of a Rapid Cytotoxicity Screening Approach To Engineer a Safer Zinc Oxide Nanoparticle through Iron Doping

(2010) Saji George et al.   ACS Nano

SiO2 nanoparticles induce global genomic hypomethylation in HaCaT cells

(2010) Chunmei Gong et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tungsten carbide cobalt nanoparticles exert hypoxia-like effects on the gene expression level in human keratinocytes

(2010) Wibke Busch et al.   BMC GENOMICS

Small noncoding RNAs: Biogenesis, function, and emerging significance in toxicology

(2010) Supratim Choudhuri   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Agglomeration, sedimentation, and cellular toxicity of alumina nanoparticles in cell culture medium

(2010) Dokyung Yoon et al.   JOURNAL OF NANOPARTICLE RESEARCH

Proteomic profiling of the differentially expressed proteins by TiO2 nanoparticles in mouse kidney

(2010) Yu-Mi Jeon et al.   Molecular & Cellular Toxicology

Stable nanoparticle aggregates/agglomerates of different sizes and the effect of their size on hemolytic cytotoxicity

(2010) Justin M. Zook et al.   Nanotoxicology

SiO2 nanoparticles induce cytotoxicity and protein expression alteration in HaCaT cells

(2010) Xifei Yang et al.   Particle and Fibre Toxicology

A comparison of acute and long-term effects of industrial multiwalled carbon nanotubes on human lung and immune cells in vitro

(2010) Tina Thurnherr et al.   TOXICOLOGY LETTERS

In Vitro Toxicity of Silver Nanoparticles at Noncytotoxic Doses to HepG2 Human Hepatoma Cells

(2009) Koji Kawata et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Cytotoxicity of nanoparticles independent from oxidative stress

(2009) Eleonore Fröhlich et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Gene expression profiles in rat lung after inhalation exposure to C60 fullerene particles

(2009) Katsuhide Fujita et al.   TOXICOLOGY

Proteomics-based safety evaluation of multi-walled carbon nanotubes

(2009) Hisao Haniu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Effects of ultrafine TiO2 particles on gene expression profile in human keratinocytes without illumination: Involvement of extracellular matrix and cell adhesion

(2009) Katsuhide Fujita et al.   TOXICOLOGY LETTERS

Comparison of gene expression profiles in mice liver following intravenous injection of 4 and 100nm-sized PEG-coated gold nanoparticles

(2009) Wan-Seob Cho et al.   TOXICOLOGY LETTERS

Assessing nanotoxicity in cells in vitro

(2009) Jedd M. Hillegass et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

DNA hypomethylation in cancer cells

(2009) Melanie Ehrlich   Epigenomics

High-Content Screening as a Universal Tool for Fingerprinting of Cytotoxicity of Nanoparticles

(2008) Edward Jan et al.   ACS Nano

Alternative Modes of Binding of Recombinant Human Histone Deacetylase 8 to Colloidal Gold Nanoparticles

(2008) Nitesh Sule et al.   Journal of Biomedical Nanotechnology

Macrophage Responses to Silica Nanoparticles are Highly Conserved Across Particle Sizes

(2008) Katrina M. Waters et al.   TOXICOLOGICAL SCIENCES

Limitations and relative utility of screening assays to assess engineered nanoparticle toxicity in a human cell line

(2008) N.A. Monteiro-Riviere et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY